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A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
Yuan, Meng, Wu, Nicholas C., Zhu, Xueyong, Lee, Chang-Chun D., So, Ray T. Y., Lv, Huibin, Mok, Chris K. P., Wilson, Ian A.
Published in Science (American Association for the Advancement of Science) (08.05.2020)
Published in Science (American Association for the Advancement of Science) (08.05.2020)
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Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies
Yuan, Meng, Liu, Hejun, Wu, Nicholas C., Wilson, Ian A.
Published in Biochemical and biophysical research communications (29.01.2021)
Published in Biochemical and biophysical research communications (29.01.2021)
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Structural basis of a shared antibody response to SARS-CoV-2
Yuan, Meng, Liu, Hejun, Wu, Nicholas C., Lee, Chang-Chun D., Zhu, Xueyong, Zhao, Fangzhu, Huang, Deli, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Rogers, Thomas F., Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R., Wilson, Ian A.
Published in Science (American Association for the Advancement of Science) (28.08.2020)
Published in Science (American Association for the Advancement of Science) (28.08.2020)
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A TLR7-nanoparticle adjuvant promotes a broad immune response against heterologous strains of influenza and SARS-CoV-2
Yin, Qian, Luo, Wei, Mallajosyula, Vamsee, Bo, Yang, Guo, Jing, Xie, Jinghang, Sun, Meng, Verma, Rohit, Li, Chunfeng, Constantz, Christian M., Wagar, Lisa E., Li, Jing, Sola, Elsa, Gupta, Neha, Wang, Chunlin, Kask, Oliver, Chen, Xin, Yuan, Xue, Wu, Nicholas C., Rao, Jianghong, Chien, Yueh-hsiu, Cheng, Jianjun, Pulendran, Bali, Davis, Mark M.
Published in Nature materials (01.03.2023)
Published in Nature materials (01.03.2023)
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Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
Rogers, Thomas F., Zhao, Fangzhu, Huang, Deli, Beutler, Nathan, Burns, Alison, He, Wan-ting, Limbo, Oliver, Smith, Chloe, Song, Ge, Woehl, Jordan, Yang, Linlin, Abbott, Robert K., Callaghan, Sean, Garcia, Elijah, Hurtado, Jonathan, Parren, Mara, Peng, Linghang, Ramirez, Sydney, Ricketts, James, Ricciardi, Michael J., Rawlings, Stephen A., Wu, Nicholas C., Yuan, Meng, Smith, Davey M., Nemazee, David, Teijaro, John R., Voss, James E., Wilson, Ian A., Andrabi, Raiees, Briney, Bryan, Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R.
Published in Science (American Association for the Advancement of Science) (21.08.2020)
Published in Science (American Association for the Advancement of Science) (21.08.2020)
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A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine
Wu, Nicholas C., Zost, Seth J., Thompson, Andrew J., Oyen, David, Nycholat, Corwin M., McBride, Ryan, Paulson, James C., Hensley, Scott E., Wilson, Ian A.
Published in PLoS pathogens (23.10.2017)
Published in PLoS pathogens (23.10.2017)
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Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants
Yuan, Meng, Huang, Deli, Lee, Chang-Chun D., Wu, Nicholas C., Jackson, Abigail M., Zhu, Xueyong, Liu, Hejun, Peng, Linghang, van Gils, Marit J., Sanders, Rogier W., Burton, Dennis R., Reincke, S. Momsen, Prüss, Harald, Kreye, Jakob, Nemazee, David, Ward, Andrew B., Wilson, Ian A.
Published in Science (American Association for the Advancement of Science) (13.08.2021)
Published in Science (American Association for the Advancement of Science) (13.08.2021)
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Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling
York, Autumn G., Williams, Kevin J., Argus, Joseph P., Zhou, Quan D., Brar, Gurpreet, Vergnes, Laurent, Gray, Elizabeth E., Zhen, Anjie, Wu, Nicholas C., Yamada, Douglas H., Cunningham, Cameron R., Tarling, Elizabeth J., Wilks, Moses Q., Casero, David, Gray, David H., Yu, Amy K., Wang, Eric S., Brooks, David G., Sun, Ren, Kitchen, Scott G., Wu, Ting-Ting, Reue, Karen, Stetson, Daniel B., Bensinger, Steven J.
Published in Cell (17.12.2015)
Published in Cell (17.12.2015)
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Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants
Lee, Juhye M., Huddleston, John, Doud, Michael B., Hooper, Kathryn A., Wu, Nicholas C., Bedford, Trevor, Bloom, Jesse D.
Published in Proceedings of the National Academy of Sciences - PNAS (28.08.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (28.08.2018)
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Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution
Liang, Weiwen, Tan, Timothy J. C., Wang, Yiquan, Lv, Huibin, Sun, Yuanxin, Bruzzone, Roberto, Mok, Chris K. P., Wu, Nicholas C.
Published in PLoS pathogens (26.09.2022)
Published in PLoS pathogens (26.09.2022)
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Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity
Liu, Hejun, Wu, Nicholas C., Yuan, Meng, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., van Schooten, Jelle, Zhu, Xueyong, Lee, Chang-Chun D., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
Published in Immunity (Cambridge, Mass.) (15.12.2020)
Published in Immunity (Cambridge, Mass.) (15.12.2020)
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Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections
Lv, Huibin, Wu, Nicholas C., Tsang, Owen Tak-Yin, Yuan, Meng, Perera, Ranawaka A.P.M., Leung, Wai Shing, So, Ray T.Y., Chan, Jacky Man Chun, Yip, Garrick K., Chik, Thomas Shiu Hong, Wang, Yiquan, Choi, Chris Yau Chung, Lin, Yihan, Ng, Wilson W., Zhao, Jincun, Poon, Leo L.M., Peiris, J.S. Malik, Wilson, Ian A., Mok, Chris K.P.
Published in Cell reports (Cambridge) (02.06.2020)
Published in Cell reports (Cambridge) (02.06.2020)
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Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020
Perera, Ranawaka APM, Mok, Chris KP, Tsang, Owen TY, Lv, Huibin, Ko, Ronald LW, Wu, Nicholas C, Yuan, Meng, Leung, Wai Shing, Chan, Jacky MC, Chik, Thomas SH, Choi, Chris YC, Leung, Kathy, Chan, Kin Ho, Chan, Karl CK, Li, Ka-Chi, Wu, Joseph T, Wilson, Ian A, Monto, Arnold S, Poon, Leo LM, Peiris, Malik
Published in Euro surveillance : bulletin européen sur les maladies transmissibles (23.04.2020)
Published in Euro surveillance : bulletin européen sur les maladies transmissibles (23.04.2020)
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An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain
Wu, Nicholas C., Yuan, Meng, Liu, Hejun, Lee, Chang-Chun D., Zhu, Xueyong, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
Published in Cell reports (Cambridge) (20.10.2020)
Published in Cell reports (Cambridge) (20.10.2020)
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Adaptation in protein fitness landscapes is facilitated by indirect paths
Wu, Nicholas C, Dai, Lei, Olson, C Anders, Lloyd-Smith, James O, Sun, Ren
Published in eLife (08.07.2016)
Published in eLife (08.07.2016)
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Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in VH1-69 Antibody Orientation on the HA Stem
Lang, Shanshan, Xie, Jia, Zhu, Xueyong, Wu, Nicholas C., Lerner, Richard A., Wilson, Ian A.
Published in Cell reports (Cambridge) (01.09.2017)
Published in Cell reports (Cambridge) (01.09.2017)
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