Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma
Flaherty, Keith T, Robert, Caroline, Hersey, Peter, Nathan, Paul, Garbe, Claus, Milhem, Mohammed, Demidov, Lev V, Hassel, Jessica C, Rutkowski, Piotr, Mohr, Peter, Dummer, Reinhard, Trefzer, Uwe, Larkin, James M.G, Utikal, Jochen, Dreno, Brigitte, Nyakas, Marta, Middleton, Mark R, Becker, Jürgen C, Casey, Michelle, Sherman, Laurie J, Wu, Frank S, Ouellet, Daniele, Martin, Anne-Marie, Patel, Kiran, Schadendorf, Dirk
Published in The New England journal of medicine (12.07.2012)
Published in The New England journal of medicine (12.07.2012)
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Journal Article
DREAMM-8: A Phase III Study of the Efficacy and Safety of Belantamab Mafodotin with Pomalidomide and Dexamethasone (B-Pd) Vs Pomalidomide Plus Bortezomib and Dexamethasone (PVd) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)
Trudel, Suzanne, Davis, Randy, Lewis, Nicole M., Bakshi, Kalpana K., Chopra, Bikramjit, Montes de Oca, Rocio, Ferron-Brady, Geraldine, Eliason, Laurie, Kremer, Brandon E., Gupta, Ira, Wu, Frank S.
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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MEK114653: A randomized, multicenter, phase II study to assess efficacy and safety of trametinib (T) compared with docetaxel (D) in KRAS -mutant advanced non–small cell lung cancer (NSCLC)
Blumenschein, George R., Smit, Egbert F., Planchard, David, Kim, Dong-Wan, Cadranel, Jacques, De Pas, Tommaso, Dunphy, Frank, Udud, Katalin, Ahn, Myung-Ju, Hanna, Nasser H., Kim, Joo-Hang, Mazieres, Julien, Kim, Sang-We, Baas, Paul, Rappold, Erica, Redhu, Suman, Bellew, Kevin M., Streit, Michael R. W., Wu, Frank S., Janne, Pasi A.
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Tumor-specific circulating cell-free DNA (cfDNA) to predict clinical outcome in BRAF V600 mutation-positive melanoma patients (pts) treated with the MEK inhibitor trametinib (T) or chemotherapy (C)
Schadendorf, Dirk, Flaherty, Keith, Hersey, Peter, Nathan, Paul D., Garbe, Claus, Milhem, Mohammed M., Demidov, Lev V., Hassel, Jessica Cecile, Rutkowski, Piotr, Mohr, Peter, Dummer, Reinhard, Trefzer, Uwe, Larkin, James M. G., Utikal, Jochen, Casey, Michelle, Santiago-Walker, Ademi, Sherman, Laurie Jill, Martin, Anne-Marie, Wu, Frank S., Robert, Caroline
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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METRIC phase III study: Efficacy of trametinib (T), a potent and selective MEK inhibitor (MEKi), in progression-free survival (PFS) and overall survival (OS), compared with chemotherapy (C) in patients (pts) with BRAF V600E/K mutant advanced or metastatic melanoma (MM)
Robert, Caroline, Flaherty, Keith T., Hersey, Peter, Nathan, Paul D., Garbe, Claus, Milhem, Mohammed M., Demidov, Lev V., Hassel, Jessica C., Rutkowski, Piotr, Mohr, Peter, Dummer, Reinhard, Trefzer, Uwe, Larkin, James M. G., Utikal, Jochen, Casey, Michelle, Sherman, Laurie Jill, Crist, Wendy A., Wu, Frank S., Patel, Kiran, Schadendorf, Dirk
Published in Journal of clinical oncology (20.06.2012)
Published in Journal of clinical oncology (20.06.2012)
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Journal Article
METRIC phase III study: Efficacy of trametinib (T), a potent and selective MEK inhibitor (MEKi), in progression-free survival (PFS) and overall survival (OS) compared with chemotherapy (C) in patients (pts) with BRAF V600/k mutant advanced or metastatic melanoma (MM)
Robert, Caroline, Flaherty, Keith T., Hersey, Peter, Nathan, Paul D., Garbe, Claus, Milhem, Mohammed M., Demidov, Lev V., Hassel, Jessica C., Rutkowski, Piotr, Mohr, Peter, Dummer, Reinhard, Trefzer, Uwe, Larkin, James M. G., Utikal, Jochen, Casey, Michelle, Sherman, Laurie Jill, Crist, Wendy A., Wu, Frank S., Patel, Kiran, Schadendorf, Dirk
Published in Journal of clinical oncology (20.05.2012)
Published in Journal of clinical oncology (20.05.2012)
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Journal Article
Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma
FLAHERTY, Keith T, ROBERT, Caroline, DUMMER, Reinhard, TREFZER, Uwe, LARKIN, James M. G, UTIKAL, Jochen, DRENO, Brigitte, NYAKAS, Marta, MIDDLETON, Mark R, BECKER, Jürgen C, CASEY, Michelle, SHERMAN, Laurie J, HERSEY, Peter, WU, Frank S, OUELLET, Daniele, MARTIN, Anne-Marie, PATEL, Kiran, SCHADENDORF, Dirk, NATHAN, Paul, GARBE, Claus, MILHEM, Mohammed, DEMIDOV, Lev V, HASSEL, Jessica C, RUTKOWSKI, Piotr, MOHR, Peter
Published in The New England journal of medicine (2012)
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Published in The New England journal of medicine (2012)
Journal Article