A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin‐induced apoptosis in castration‐resistant prostate cancer
Ye, Pei‐Chen, Leu, Wohn‐Jenn, Yeh, Tsung‐Yu, Hsu, Yu‐Tung, Lin, Yi‐Chin, Wei, Zi‐Yuan, Chen, Yi‐Chin, Chiang, Yi‐Chang, Hsu, Jui‐Ling, Chan, She‐Hung, Hsu, Lih‐Ching, Chern, Ji‐Wang, Yu, Chao‐Wu, Guh, Jih‐Hwa
Published in The Prostate (01.05.2024)
Published in The Prostate (01.05.2024)
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Discovery of novel anaplastic lymphoma kinase (ALK) and histone deacetylase (HDAC) dual inhibitors exhibiting antiproliferative activity against non-small cell lung cancer
Wang, Kang-Li, Yeh, Tsung-Yu, Hsu, Pei-Chen, Wong, Tzu-Hsuan, Liu, Jia-Rong, Chern, Ji-Wang, Lin, Miao-Hsia, Yu, Chao-Wu
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2024)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2024)
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Efficient Microwave-Assisted Pd-Catalyzed Hydroxylation of Aryl Chlorides in the Presence of Carbonate
Yu, Chao-Wu, Chen, Grace S, Huang, Chen-Wei, Chern, Ji-Wang
Published in Organic letters (20.07.2012)
Published in Organic letters (20.07.2012)
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A highly HDAC6-selective inhibitor acts as a fluorescent probe
Ho, Yi-Hsun, Wang, Kuang-Jui, Hung, Pei-Yun, Cheng, Yi-Sheng, Liu, Jia-Rong, Fung, Sheang-Tze, Liang, Pi-Hui, Chern, Ji-Wang, Yu, Chao-Wu
Published in Organic & biomolecular chemistry (31.10.2018)
Published in Organic & biomolecular chemistry (31.10.2018)
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Journal Article
Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome
Pan, Zhijian, Yu, Chao-Wu, Zhao, Chen, Shao, Min, Yang, Xuanjun, Liang, Xiaonan, Li, Haitao, Lu, Yucong, Ye, Qingqing, Chern, Ji-Wang, Lu, Jiahong, Zhou, Hefeng, Lee, Simon Ming-Yuen
Published in Toxicology and applied pharmacology (01.12.2023)
Published in Toxicology and applied pharmacology (01.12.2023)
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Quinazolin-2,4-dione-Based Hydroxamic Acids as Selective Histone Deacetylase‑6 Inhibitors for Treatment of Non-Small Cell Lung Cancer
Yu, Chao-Wu, Hung, Pei-Yun, Yang, Hui-Ting, Ho, Yi-Hsun, Lai, Hsing-Yi, Cheng, Yi-Sheng, Chern, Ji-Wang
Published in Journal of medicinal chemistry (24.01.2019)
Published in Journal of medicinal chemistry (24.01.2019)
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Discovery of HDAC6, HDAC8, and 6/8 Inhibitors and Development of Cell-Based Drug Screening Models for the Treatment of TGF-β-Induced Idiopathic Pulmonary Fibrosis
Yu, Wei-Chieh, Yeh, Tsung-Yu, Ye, Chih-Hung, Chong, Patrick Chun Theng, Ho, Yi-Hsun, So, Dorothy Kazuno, Yap, Kah Yi, Peng, Guan-Ru, Shao, Chi-Hsuan, Jagtap, Ajit Dhananjay, Chern, Ji-Wang, Lin, Chen-Si, Lin, Shau-Ping, Lin, Shuei-Liong, Yu, Shu-Han, Yu, Chao-Wu
Published in Journal of medicinal chemistry (10.08.2023)
Published in Journal of medicinal chemistry (10.08.2023)
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J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice
Pan, Zhijian, Shao, Min, Zhao, Chen, Yang, Xuanjun, Li, Haitao, Cui, Guozhen, Liang, Xiaonan, Yu, Chao-Wu, Ye, Qingqing, Gao, Cheng, Di, Lijun, Chern, Ji-Wang, Zhou, Hefeng, Lee, Simon Ming-Yuen
Published in European journal of pharmaceutical sciences (01.03.2024)
Published in European journal of pharmaceutical sciences (01.03.2024)
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Effect of stabilizing treatment on microstructure and stress rupture properties of phosphorus microalloyed Inconel 706 alloy
Zhang, Sha, Wu, Yu-chao, Li, Yu, Dai, Zhong-pei, Jia, Dan, Xu, Yan-fei, Zeng, Guang-sheng, Guo, Zhi-ming, Liu, Jian
Published in Journal of iron and steel research, international (01.08.2023)
Published in Journal of iron and steel research, international (01.08.2023)
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Convergence-Enhanced Subspace Channel Estimation for MIMO-OFDM Systems with Virtual Carriers
Zhang, Biling, Yu, Jung-Lang, Yuan, Yipu, Wu, Chao-Yu
Published in Circuits, systems, and signal processing (01.06.2017)
Published in Circuits, systems, and signal processing (01.06.2017)
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Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity
Peng, Cheng, Li, Yu-Hsuan, Yu, Chao-Wu, Cheng, Ze-Hua, Liu, Jia-Rong, Hsu, Jui-Ling, Hsin, Ling-Wei, Huang, Chen-Tsung, Juan, Hsueh-Fen, Chern, Ji-Wang, Cheng, Yi-Sheng
Published in Bioorganic chemistry (01.05.2021)
Published in Bioorganic chemistry (01.05.2021)
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A newly designed molecule J2326 for Alzheimer's disease disaggregates amyloid fibrils and induces neurite outgrowth
Chang, Pei-Teh, Talekar, Rahul Subhash, Kung, Fan-Lu, Chern, Ting-Rong, Huang, Chen-Wei, Ye, Qing-qing, Yang, Min-Yan, Yu, Chao-Wu, Lai, Shin-Yu, Deore, Ravindra Ramesh, Lin, Jung-Hsin, Chen, Chien-Shu, Chen, Grace Shiahuy, Chern, Ji-Wang
Published in Neuropharmacology (01.05.2015)
Published in Neuropharmacology (01.05.2015)
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