Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies
Wright, Galen E B, Black, Hailey Findlay, Collins, Jennifer A, Gall-Duncan, Terence, Caron, Nicholas S, Pearson, Christopher E, Hayden, Michael R
Published in Lancet neurology (01.11.2020)
Published in Lancet neurology (01.11.2020)
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Journal Article
Transcriptome-wide association study uncovers the role of essential genes in anthracycline-induced cardiotoxicity
Scott, Erika N., Wright, Galen E. B., Drögemöller, Britt I., Hasbullah, Jafar S., Gunaretnam, Erandika P., Miao, Fudan, Bhavsar, Amit P., Shen, Fei, Schneider, Bryan P., Carleton, Bruce C., Ross, Colin J. D.
Published in Npj genomic medicine (21.05.2021)
Published in Npj genomic medicine (21.05.2021)
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Journal Article
Elucidation of CYP2D6 Genetic Diversity in a Unique African Population: Implications for the Future Application of Pharmacogenetics in the Xhosa Population
Wright, Galen E. B., Niehaus, Dana J. H., Drögemöller, Britt I., Koen, Liezl, Gaedigk, Andrea, Warnich, Louise
Published in Annals of human genetics (01.07.2010)
Published in Annals of human genetics (01.07.2010)
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Journal Article
Frequency of the loss of CAA interruption in the HTT CAG tract and implications for Huntington disease in the reduced penetrance range
Findlay Black, Hailey, Wright, Galen E. B., Collins, Jennifer A., Caron, Nicholas, Kay, Chris, Xia, Qingwen, Arning, Larissa, Bijlsma, Emilia K., Squitieri, Ferdinando, Nguyen, Huu Phuc, Hayden, Michael R.
Published in Genetics in medicine (01.12.2020)
Published in Genetics in medicine (01.12.2020)
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Journal Article
A multi-centre, tolerability study of a cannabidiol-enriched Cannabis Herbal Extract for chronic headaches in adolescents: The CAN-CHA protocol
Chhabra, Manik, Lewis, Evan C, Balshaw, Robert, Stewart, Breanne, Zaslawski, Zina, Lowthian, Trinity, Alidina, Zahra, Chesick-Gordis, Melila, Xie, Wenli, Drögemöller, Britt I, Wright, Galen E B, Birnie, Kathryn A, Boerner, Katelynn E, Tsang, Vivian W L, Irwin, Samantha Lee, Pohl, Daniela, Weil, Alexander G, Sell, Erick, Penz, Erika, Robson-MacKay, Amy, Mbabaali, Sophia, Blackman, Stephanie, Gordon, Shanlea, Alcorn, Jane, Huntsman, Richard J, Oberlander, Tim F, Finley, G Allen, Kelly, Lauren E
Published in PloS one (20.09.2024)
Published in PloS one (20.09.2024)
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Journal Article
A systematic comparison of pharmacogene star allele calling bioinformatics algorithms: a focus on CYP2D6 genotyping
Twesigomwe, David, Wright, Galen E. B., Drögemöller, Britt I., da Rocha, Jorge, Lombard, Zané, Hazelhurst, Scott
Published in Npj genomic medicine (03.08.2020)
Published in Npj genomic medicine (03.08.2020)
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Journal Article
Association of MB-COMT polymorphisms with schizophrenia-susceptibility and symptom severity in an African cohort
Wright, Galen E.B., Niehaus, Dana J.H., van der Merwe, Lize, Koen, Liezl, Korkie, Lundi J., Kinnear, Craig J., Drögemöller, Britt I., Warnich, Louise
Published in Progress in neuro-psychopharmacology & biological psychiatry (01.10.2012)
Published in Progress in neuro-psychopharmacology & biological psychiatry (01.10.2012)
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Journal Article
CYP2D6 as a treatment decision aid for ER-positive non-metastatic breast cancer patients: a systematic review with accompanying clinical practice guidelines
Drögemöller, Britt I., Wright, Galen E. B., Shih, Joanne, Monzon, Jose G., Gelmon, Karen A., Ross, Colin J. D., Amstutz, Ursula, Carleton, Bruce C.
Published in Breast cancer research and treatment (01.02.2019)
Published in Breast cancer research and treatment (01.02.2019)
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Journal Article
The molecular epidemiology of Huntington disease is related to intermediate allele frequency and haplotype in the general population
Kay, Chris, Collins, Jennifer A., Wright, Galen E.B., Baine, Fiona, Miedzybrodzka, Zosia, Aminkeng, Folefac, Semaka, Alicia J., McDonald, Cassandra, Davidson, Mark, Madore, Steven J., Gordon, Erynn S., Gerry, Norman P., Cornejo‐Olivas, Mario, Squitieri, Ferdinando, Tishkoff, Sarah, Greenberg, Jacquie L., Krause, Amanda, Hayden, Michael R.
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01.04.2018)
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01.04.2018)
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Journal Article
Integrative Neuroinformatics for Precision Prognostication and Personalized Therapeutics in Moderate and Severe Traumatic Brain Injury
Zeiler, Frederick A, Iturria-Medina, Yasser, Thelin, Eric P, Gomez, Alwyn, Shankar, Jai J, Ko, Ji Hyun, Figley, Chase R, Wright, Galen E B, Anderson, Chris M
Published in Frontiers in neurology (07.09.2021)
Published in Frontiers in neurology (07.09.2021)
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Journal Article
A cross-sectional study of the relationship between CYP2D6 and CYP2C19 variations and depression symptoms, for women taking SSRIs during pregnancy
Hippman, Catriona, Slomp, Caitlin, Morris, Emily, Batallones, Rolan, Inglis, Angela, Carrion, Prescilla, Brain, Ursula, Higginson, Michelle, Wright, Galen E. B., Balneaves, Lynda G., Ryan, Deirdre, Nislow, Corey, Ross, Colin J. D., Gaedigk, Andrea, Oberlander, Tim F., Austin, Jehannine
Published in Archives of women's mental health (01.04.2022)
Published in Archives of women's mental health (01.04.2022)
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Journal Article
Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis
Kowalec, Kaarina, Wright, Galen E. B., Drögemöller, Britt I., Aminkeng, Folefac, Bhavsar, Amit P., Kingwell, Elaine, Yoshida, Eric M., Traboulsee, Anthony, Marrie, Ruth Ann, Kremenchutzky, Marcelo, Campbell, Trudy L., Duquette, Pierre, Chalasani, Naga, Wadelius, Mia, Hallberg, Pär, Xia, Zongqi, De Jager, Philip L., Denny, Joshua C., Davis, Mary F., Ross, Colin J. D., Tremlett, Helen, Carleton, Bruce C.
Published in Nature genetics (01.08.2018)
Published in Nature genetics (01.08.2018)
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Journal Article
Further Investigation of the Role of ACYP2 and WFS1 Pharmacogenomic Variants in the Development of Cisplatin-Induced Ototoxicity in Testicular Cancer Patients
Drögemöller, Britt I, Brooks, Beth, Critchley, Carol, Monzon, José G, Wright, Galen E B, Liu, Geoffrey, Renouf, Daniel J, Kollmannsberger, Christian K, Bedard, Philippe L, Hayden, Michael R, Gelmon, Karen A, Carleton, Bruce C, Ross, Colin J D
Published in Clinical cancer research (15.04.2018)
Published in Clinical cancer research (15.04.2018)
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Journal Article
Association Between SLC16A5 Genetic Variation and Cisplatin-Induced Ototoxic Effects in Adult Patients With Testicular Cancer
Drögemöller, Britt I, Monzon, Jose G, Bhavsar, Amit P, Borrie, Adrienne E, Brooks, Beth, Wright, Galen E B, Liu, Geoffrey, Renouf, Daniel J, Kollmannsberger, Christian K, Bedard, Philippe L, Aminkeng, Folefac, Amstutz, Ursula, Hildebrand, Claudette A, Gunaretnam, Erandika P, Critchley, Carol, Chen, Zhuo, Brunham, Liam R, Hayden, Michael R, Ross, Colin J D, Gelmon, Karen A, Carleton, Bruce C
Published in JAMA oncology (01.11.2017)
Published in JAMA oncology (01.11.2017)
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Journal Article
CYP2B66 and CYP2B618 Predict Long-Term Efavirenz Exposure Measured in Hair Samples in HIV-Positive South African Women
Röhrich, Carola R, Drögemöller, Britt I, Ikediobi, Ogechi, van der Merwe, Lize, Grobbelaar, Nelis, Wright, Galen E B, McGregor, Nathaniel, Warnich, Louise
Published in AIDS research and human retroviruses (01.06.2016)
Published in AIDS research and human retroviruses (01.06.2016)
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Journal Article
Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study
Dodgen, Tyren M, Hochfeld, Warren E, Fickl, Heidi, Asfaha, Sahle M, Durandt, Chrisna, Rheeder, Paul, Drögemöller, Britt I, Wright, Galen E B, Warnich, Louise, Labuschagne, Christiaan D J, van Schalkwyk, Antoinette, Gaedigk, Andrea, Pepper, Michael S
Published in BMC genetics (29.01.2013)
Published in BMC genetics (29.01.2013)
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Journal Article
Ethical and legal implications of whole genome and whole exome sequencing in African populations
Wright, Galen E B, Koornhof, Pieter G J, Adeyemo, Adebowale A, Tiffin, Nicki
Published in BMC medical ethics (28.05.2013)
Published in BMC medical ethics (28.05.2013)
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