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Published in Lancet neurology (01.03.2015)
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Published in Nature neuroscience (01.08.2016)
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Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia
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Published in Cell reports (Cambridge) (15.01.2019)
Published in Cell reports (Cambridge) (15.01.2019)
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Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies
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Published in Biomolecules (06.01.2016)
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Imamura, Keiko, Izumi, Yuishin, Watanabe, Akira, Tsukita, Kayoko, Woltjen, Knut, Yamamoto, Takuya, Hotta, Akitsu, Kondo, Takayuki, Kitaoka, Shiho, Ohta, Akira, Tanaka, Akito, Watanabe, Dai, Morita, Mitsuya, Takuma, Hiroshi, Tamaoka, Akira, Kunath, Tilo, Wray, Selina, Furuya, Hirokazu, Era, Takumi, Makioka, Kouki, Okamoto, Koichi, Fujisawa, Takao, Nishitoh, Hideki, Homma, Kengo, Ichijo, Hidenori, Julien, Jean-Pierre, Obata, Nanako, Hosokawa, Masato, Akiyama, Haruhiko, Kaneko, Satoshi, Ayaki, Takashi, Ito, Hidefumi, Kaji, Ryuji, Takahashi, Ryosuke, Yamanaka, Shinya, Inoue, Haruhisa
Published in Science translational medicine (24.05.2017)
Published in Science translational medicine (24.05.2017)
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Familial Alzheimer’s Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis
Arber, Charles, Lovejoy, Christopher, Harris, Lachlan, Willumsen, Nanet, Alatza, Argyro, Casey, Jackie M., Lines, Georgie, Kerins, Caoimhe, Mueller, Anika K., Zetterberg, Henrik, Hardy, John, Ryan, Natalie S., Fox, Nick C., Lashley, Tammaryn, Wray, Selina
Published in Cell reports (Cambridge) (12.01.2021)
Published in Cell reports (Cambridge) (12.01.2021)
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G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo
Simone, Roberto, Balendra, Rubika, Moens, Thomas G, Preza, Elisavet, Wilson, Katherine M, Heslegrave, Amanda, Woodling, Nathan S, Niccoli, Teresa, Gilbert‐Jaramillo, Javier, Abdelkarim, Samir, Clayton, Emma L, Clarke, Mica, Konrad, Marie‐Therese, Nicoll, Andrew J, Mitchell, Jamie S, Calvo, Andrea, Chio, Adriano, Houlden, Henry, Polke, James M, Ismail, Mohamed A, Stephens, Chad E, Vo, Tam, Farahat, Abdelbasset A, Wilson, W David, Boykin, David W, Zetterberg, Henrik, Partridge, Linda, Wray, Selina, Parkinson, Gary, Neidle, Stephen, Patani, Rickie, Fratta, Pietro, Isaacs, Adrian M
Published in EMBO molecular medicine (01.01.2018)
Published in EMBO molecular medicine (01.01.2018)
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Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages
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Published in Scientific reports (21.08.2017)
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Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration
Esteras, Noemí, Rohrer, Jonathan D, Hardy, John, Wray, Selina, Abramov, Andrey Y
Published in Redox biology (01.08.2017)
Published in Redox biology (01.08.2017)
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Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS
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Published in Cell reports (Cambridge) (30.05.2017)
Published in Cell reports (Cambridge) (30.05.2017)
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MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
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Published in Human molecular genetics (15.09.2012)
Published in Human molecular genetics (15.09.2012)
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Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease
Rajani, Rikesh M, Ellingford, Robert, Hellmuth, Mariam, Harris, Samuel S, Taso, Orjona S, Graykowski, David, Lam, Francesca Kar Wey, Arber, Charles, Fertan, Emre, Danial, John S H, Swire, Matthew, Lloyd, Marcus, Giovannucci, Tatiana A, Bourdenx, Mathieu, Klenerman, David, Vassar, Robert, Wray, Selina, Sala Frigerio, Carlo, Busche, Marc Aurel
Published in PLoS biology (01.07.2024)
Published in PLoS biology (01.07.2024)
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Miller, Sean J., Wray, Selina, Sattler, Rita, Zhang, Can
Published in Frontiers in neuroscience (30.06.2022)
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Genetically engineered MAPT 10+16 mutation causes pathophysiological excitability of human iPSC-derived neurons related to 4R tau-induced dementia
Kopach, Olga, Esteras, Noemí, Wray, Selina, Abramov, Andrey Y., Rusakov, Dmitri A.
Published in Cell death & disease (17.07.2021)
Published in Cell death & disease (17.07.2021)
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Hanger, Diane P., Byers, Helen L., Wray, Selina, Leung, Kit-Yi, Saxton, Malcolm J., Seereeram, Anjan, Reynolds, C. Hugh, Ward, Malcolm A., Anderton, Brian H.
Published in The Journal of biological chemistry (10.08.2007)
Published in The Journal of biological chemistry (10.08.2007)
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Gabriele, Rebecca M C, Abel, Emily, Fox, Nick C, Wray, Selina, Arber, Charles
Published in Frontiers in neuroscience (14.03.2022)
Published in Frontiers in neuroscience (14.03.2022)
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Pathogenic VCP Mutations Induce Mitochondrial Uncoupling and Reduced ATP Levels
Bartolome, Fernando, Wu, Hsiu-Chuan, Burchell, Victoria S., Preza, Elisavet, Wray, Selina, Mahoney, Colin J., Fox, Nick C., Calvo, Andrea, Canosa, Antonio, Moglia, Cristina, Mandrioli, Jessica, Chiò, Adriano, Orrell, Richard W., Houlden, Henry, Hardy, John, Abramov, Andrey Y., Plun-Favreau, Helene
Published in Neuron (Cambridge, Mass.) (10.04.2013)
Published in Neuron (Cambridge, Mass.) (10.04.2013)
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iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease
Arber, Charles, Angelova, Plamena R, Wiethoff, Sarah, Tsuchiya, Yugo, Mazzacuva, Francesca, Preza, Elisavet, Bhatia, Kailash P, Mills, Kevin, Gout, Ivan, Abramov, Andrey Y, Hardy, John, Duce, James A, Houlden, Henry, Wray, Selina
Published in PloS one (01.09.2017)
Published in PloS one (01.09.2017)
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