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Site-specific glycan analysis of the SARS-CoV-2 spike
Watanabe, Yasunori, Allen, Joel D, Wrapp, Daniel, McLellan, Jason S, Crispin, Max
Published in Science (American Association for the Advancement of Science) (17.07.2020)
Published in Science (American Association for the Advancement of Science) (17.07.2020)
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Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies
Wrapp, Daniel, De Vlieger, Dorien, Corbett, Kizzmekia S., Torres, Gretel M., Wang, Nianshuang, Van Breedam, Wander, Roose, Kenny, van Schie, Loes, Hoffmann, Markus, Pöhlmann, Stefan, Graham, Barney S., Callewaert, Nico, Schepens, Bert, Saelens, Xavier, McLellan, Jason S.
Published in Cell (28.05.2020)
Published in Cell (28.05.2020)
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Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
Kirchdoerfer, Robert N., Wang, Nianshuang, Pallesen, Jesper, Wrapp, Daniel, Turner, Hannah L., Cottrell, Christopher A., Corbett, Kizzmekia S., Graham, Barney S., McLellan, Jason S., Ward, Andrew B.
Published in Scientific reports (24.10.2018)
Published in Scientific reports (24.10.2018)
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Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
Hsieh, Ching-Lin, Goldsmith, Jory A., Schaub, Jeffrey M., DiVenere, Andrea M., Kuo, Hung-Che, Javanmardi, Kamyab, Le, Kevin C., Wrapp, Daniel, Lee, Alison G., Liu, Yutong, Chou, Chia-Wei, Byrne, Patrick O., Hjorth, Christy K., Johnson, Nicole V., Ludes-Meyers, John, Nguyen, Annalee W., Park, Juyeon, Wang, Nianshuang, Amengor, Dzifa, Lavinder, Jason J., Ippolito, Gregory C., Maynard, Jennifer A., Finkelstein, Ilya J., McLellan, Jason S.
Published in Science (American Association for the Advancement of Science) (18.09.2020)
Published in Science (American Association for the Advancement of Science) (18.09.2020)
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Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
Pallesen, Jesper, Wang, Nianshuang, Corbett, Kizzmekia S., Wrapp, Daniel, Kirchdoerfer, Robert N., Turner, Hannah L., Cottrell, Christopher A., Becker, Michelle M., Wang, Lingshu, Shi, Wei, Kong, Wing-Pui, Andres, Erica L., Kettenbach, Arminja N., Denison, Mark R., Chappell, James D., Graham, Barney S., Ward, Andrew B., McLellan, Jason S.
Published in Proceedings of the National Academy of Sciences - PNAS (29.08.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (29.08.2017)
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Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
Rappazzo, C. Garrett, Tse, Longping V., Kaku, Chengzi I., Wrapp, Daniel, Sakharkar, Mrunal, Huang, Deli, Deveau, Laura M., Yockachonis, Thomas J., Herbert, Andrew S., Battles, Michael B., O’Brien, Cecilia M., Brown, Michael E., Geoghegan, James C., Belk, Jonathan, Peng, Linghang, Yang, Linlin, Hou, Yixuan, Scobey, Trevor D., Burton, Dennis R., Nemazee, David, Dye, John M., Voss, James E., Gunn, Bronwyn M., McLellan, Jason S., Baric, Ralph S., Gralinski, Lisa E., Walker, Laura M.
Published in Science (American Association for the Advancement of Science) (19.02.2021)
Published in Science (American Association for the Advancement of Science) (19.02.2021)
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Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape
Ku, Zhiqiang, Xie, Xuping, Davidson, Edgar, Ye, Xiaohua, Su, Hang, Menachery, Vineet D., Li, Yize, Yuan, Zihao, Zhang, Xianwen, Muruato, Antonio E., i Escuer, Ariadna Grinyo, Tyrell, Breanna, Doolan, Kyle, Doranz, Benjamin J., Wrapp, Daniel, Bates, Paul F., McLellan, Jason S., Weiss, Susan R., Zhang, Ningyan, Shi, Pei-Yong, An, Zhiqiang
Published in Nature communications (20.01.2021)
Published in Nature communications (20.01.2021)
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A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants
Zhu, Qing, McLellan, Jason S, Kallewaard, Nicole L, Ulbrandt, Nancy D, Palaszynski, Susan, Zhang, Jing, Moldt, Brian, Khan, Anis, Svabek, Catherine, McAuliffe, Josephine M, Wrapp, Daniel, Patel, Nita K, Cook, Kimberly E, Richter, Bettina W M, Ryan, Patricia C, Yuan, Andy Q, Suzich, JoAnn A
Published in Science translational medicine (03.05.2017)
Published in Science translational medicine (03.05.2017)
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Local computational methods to improve the interpretability and analysis of cryo-EM maps
Kaur, Satinder, Gomez-Blanco, Josue, Khalifa, Ahmad A. Z., Adinarayanan, Swathi, Sanchez-Garcia, Ruben, Wrapp, Daniel, McLellan, Jason S., Bui, Khanh Huy, Vargas, Javier
Published in Nature communications (23.02.2021)
Published in Nature communications (23.02.2021)
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Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies
Wrapp, Daniel, De Vlieger, Dorien, Corbett, Kizzmekia S., Torres, Gretel M., Wang, Nianshuang, Van Breedam, Wander, Roose, Kenny, van Schie, Loes, Hoffmann, Markus, Pöhlmann, Stefan, Graham, Barney S., Callewaert, Nico, Schepens, Bert, Saelens, Xavier, McLellan, Jason S.
Published in Cell (11.06.2020)
Published in Cell (11.06.2020)
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Prolonged evolution of the human B cell response to SARS-CoV-2 infection
Sakharkar, Mrunal, Rappazzo, C Garrett, Wieland-Alter, Wendy F, Hsieh, Ching-Lin, Wrapp, Daniel, Esterman, Emma S, Kaku, Chengzi I, Wec, Anna Z, Geoghegan, James C, McLellan, Jason S, Connor, Ruth I, Wright, Peter F, Walker, Laura M
Published in Science immunology (23.02.2021)
Published in Science immunology (23.02.2021)
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A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus
Jenks, Jennifer A., Amin, Sharmi, Sponholtz, Madeline R., Kumar, Amit, Wrapp, Daniel, Venkatayogi, Sravani, Tu, Joshua J., Karthigeyan, Krithika, Valencia, Sarah M., Connors, Megan, Harnois, Melissa J., Hora, Bhavna, Rochat, Eric, McLellan, Jason S., Wiehe, Kevin, Permar, Sallie R.
Published in PLoS pathogens (20.01.2023)
Published in PLoS pathogens (20.01.2023)
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Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state
Rossey, Iebe, Gilman, Morgan S. A., Kabeche, Stephanie C., Sedeyn, Koen, Wrapp, Daniel, Kanekiyo, Masaru, Chen, Man, Mas, Vicente, Spitaels, Jan, Melero, José A., Graham, Barney S., Schepens, Bert, McLellan, Jason S., Saelens, Xavier
Published in Nature communications (13.02.2017)
Published in Nature communications (13.02.2017)
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Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera
Hutchinson, Geoffrey B., Abiona, Olubukola M., Ziwawo, Cynthia T., Werner, Anne P., Ellis, Daniel, Tsybovsky, Yaroslav, Leist, Sarah R., Palandjian, Charis, West, Ande, Fritch, Ethan J., Wang, Nianshuang, Wrapp, Daniel, Boyoglu-Barnum, Seyhan, Ueda, George, Baker, David, Kanekiyo, Masaru, McLellan, Jason S., Baric, Ralph S., King, Neil P., Graham, Barney S., Corbett-Helaire, Kizzmekia S.
Published in Nature communications (04.10.2023)
Published in Nature communications (04.10.2023)
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A Combination of Receptor-Binding Domain and N-Terminal Domain Neutralizing Antibodies Limits the Generation of SARS-CoV-2 Spike Neutralization-Escape Mutants
Haslwanter, Denise, Dieterle, M. Eugenia, Wec, Anna Z., O’Brien, Cecilia M., Sakharkar, Mrunal, Florez, Catalina, Tong, Karen, Rappazzo, C. Garrett, Lasso, Gorka, Vergnolle, Olivia, Wirchnianski, Ariel S., Bortz, Robert H., Laudermilch, Ethan, Fels, J. Maximilian, Mengotto, Amanda, Malonis, Ryan J., Georgiev, George I., Quiroz, Jose A., Wrapp, Daniel, Wang, Nianshuang, Dye, Kathryn E., Barnhill, Jason, Dye, John M., McLellan, Jason S., Daily, Johanna P., Lai, Jonathan R., Herbert, Andrew S., Walker, Laura M., Chandran, Kartik, Jangra, Rohit K.
Published in mBio (26.10.2021)
Published in mBio (26.10.2021)
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Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step
Ye, Xiaohua, Su, Hang, Wrapp, Daniel, Freed, Daniel C., Li, Fengsheng, Yuan, Zihao, Tang, Aimin, Li, Leike, Ku, Zhiqiang, Xiong, Wei, Jaijyan, Dabbu, Zhu, Hua, Wang, Dai, McLellan, Jason S., Zhang, Ningyan, Fu, Tong-Ming, An, Zhiqiang
Published in PLoS pathogens (03.08.2020)
Published in PLoS pathogens (03.08.2020)
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Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition
Kramer, Kevin J., Johnson, Nicole V., Shiakolas, Andrea R., Suryadevara, Naveenchandra, Periasamy, Sivakumar, Raju, Nagarajan, Williams, Jazmean K., Wrapp, Daniel, Zost, Seth J., Walker, Lauren M., Wall, Steven C., Holt, Clinton M., Hsieh, Ching-Lin, Sutton, Rachel E., Paulo, Ariana, Nargi, Rachel S., Davidson, Edgar, Doranz, Benjamin J., Crowe, James E., Bukreyev, Alexander, Carnahan, Robert H., McLellan, Jason S., Georgiev, Ivelin S.
Published in Cell reports (Cambridge) (05.10.2021)
Published in Cell reports (Cambridge) (05.10.2021)
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