Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies
Hing, Z A, Fung, H Y J, Ranganathan, P, Mitchell, S, El-Gamal, D, Woyach, J A, Williams, K, Goettl, V M, Smith, J, Yu, X, Meng, X, Sun, Q, Cagatay, T, Lehman, A M, Lucas, D M, Baloglu, E, Shacham, S, Kauffman, M G, Byrd, J C, Chook, Y M, Garzon, R, Lapalombella, R
Published in Leukemia (01.12.2016)
Published in Leukemia (01.12.2016)
Get full text
Journal Article
Management of chronic lymphocytic leukemia (CLL) in the elderly: a position paper from an international Society of Geriatric Oncology (SIOG) Task Force
Stauder, R., Eichhorst, B., Hamaker, M.E., Kaplanov, K., Morrison, V.A., Österborg, A., Poddubnaya, I., Woyach, J.A., Shanafelt, T., Smolej, L., Ysebaert, L., Goede, V.
Published in Annals of oncology (01.02.2017)
Published in Annals of oncology (01.02.2017)
Get full text
Journal Article
Risk factors for tumor lysis syndrome in patients with chronic lymphocytic leukemia treated with the cyclin-dependent kinase inhibitor, flavopiridol
BLUM, K. A, RUPPERT, A. S, JOHNSON, A. J, GREVER, M. R, BYRD, J. C, WOYACH, J. A, JONES, J. A, ANDRITSOS, L, FLYNN, J. M, ROVIN, B, VILLALONA-CALERO, M, JI, J, PHELPS, M
Published in Leukemia (01.09.2011)
Published in Leukemia (01.09.2011)
Get full text
Journal Article
A phase I II study of rituximab and etanercept in patients with chronic lymphocytic leukemia and small lymphocytic lymphoma
WOYACH, J. A, LIN, T. S, LUCAS, M. S, HEEREMA, N, MORAN, M. E, CHENEY, C, LUCAS, D. M, WEI, L, CALIGIURI, M. A, BYRD, J. C
Published in Leukemia (01.05.2009)
Published in Leukemia (01.05.2009)
Get full text
Journal Article
PLCG2 C2 domain mutations co-occur with BTK and PLCG2 resistance mutations in chronic lymphocytic leukemia undergoing ibrutinib treatment
Jones, D, Woyach, J A, Zhao, W, Caruthers, S, Tu, H, Coleman, J, Byrd, J C, Johnson, A J, Lozanski, G
Published in Leukemia (01.07.2017)
Published in Leukemia (01.07.2017)
Get full text
Journal Article
Incidence and description of autoimmune cytopenias during treatment with ibrutinib for chronic lymphocytic leukemia
Rogers, K A, Ruppert, A S, Bingman, A, Andritsos, L A, Awan, F T, Blum, K A, Flynn, J M, Jaglowski, S M, Lozanski, G, Maddocks, K J, Byrd, J C, Woyach, J A, Jones, J A
Published in Leukemia (01.02.2016)
Published in Leukemia (01.02.2016)
Get full text
Journal Article
Application of a sequential multiple assignment randomized trial (SMART) design in older patients with chronic lymphocytic leukemia
Ruppert, A.S., Yin, J., Davidian, M., Tsiatis, A.A., Byrd, J.C., Woyach, J.A., Mandrekar, S.J.
Published in Annals of oncology (01.04.2019)
Published in Annals of oncology (01.04.2019)
Get full text
Journal Article
Characterization of Mechanisms of Resistance in Previously Treated Chronic Lymphocytic Leukemia (CLL) From a Head‐to‐Head Trial of Acalabrutinib Versus Ibrutinib
Woyach, J. A., Jones, D., Jurczak, W., Robak, T., Illés, A., Kater, A. P., Ghia, P., Byrd, J. C., Seymour, J. F., Long, S., Mohamed, N., Jesus, G., Lai, R., Bruin, G., Butturini, A., Rule, S., Munugalavadla, V.
Published in Hematological oncology (01.06.2023)
Published in Hematological oncology (01.06.2023)
Get full text
Journal Article
GENOMIC EVOLUTION AND RESISTANCE TO PIRTOBRUTINIB IN COVALENT BTK‐INHIBITOR PRE‐TREATED CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS: RESULTS FROM THE PHASE I/II BRUIN STUDY
Patel, K., Brown, J. R., Desikan, S. P., Nguyen, B., Won, H., Tantawy, S. I., McNeely, S. C., Marella, N., Ebata, K., Woyach, J. A., Tam, C. S., Eyre, T. A., Cheah, C. Y., Shah, N. N., Ghia, P., Jurczak, W., Balbas, M., Nair, B., Abada, P., Wang, C., Wang, D., Mato, A. R., Gandhi, V., Wierda, W. G.
Published in Hematological oncology (01.06.2023)
Published in Hematological oncology (01.06.2023)
Get full text
Journal Article
Outcome of patients with relapsed or refractory chronic lymphocytic leukemia treated with flavopiridol: impact of genetic features
Woyach, J A, Lozanski, G, Ruppert, A S, Lozanski, A, Blum, K A, Jones, J A, Flynn, J M, Johnson, A J, Grever, M R, Heerema, N A, Byrd, J C
Published in Leukemia (01.06.2012)
Published in Leukemia (01.06.2012)
Get full text
Journal Article
PB1863: BRUIN CLL‐322: A PHASE 3 OPEN‐LABEL, RANDOMIZED STUDY OF FIXED DURATION PIRTOBRUTINIB+VENETOCLAX AND RITUXIMAB VS VENETOCLAX AND RITUXIMAB IN PREVIOUSLY TREATED CLL/SLL (TRIAL IN PROGRESS)
Mato, A. R., Wierda, W. G., Pagel, J. M., Davids, M. S., Zinzani, P. L., Lu, Y., Liu, H., Shahda, S., Leow, C. C., Tam, C. S., Woyach, J. A., Eyre, T. A.
Published in HemaSphere (23.06.2022)
Published in HemaSphere (23.06.2022)
Get full text
Journal Article
P666: ACALABRUTINIB ± OBINUTUZUMAB VS OBINUTUZUMAB + CHLORAMBUCIL IN TREATMENT‐NAIVE CHRONIC LYMPHOCYTIC LEUKEMIA: 5‐YEAR FOLLOW‐UP OF ELEVATE‐TN
Sharman, J. P., Egyed, M., Jurczak, W., Skarbnik, A., Patel, K., Flinn, I. W., Kamdar, M., Munir, T., Walewska, R., Fogliatto, L. M., Herishanu, Y., Banerji, V., Follows, G., Walker, P., Karlsson, K., Ghia, P., Janssens, A., Cymbalista, F., Ferrant, E., Wierda, W. G., Munugalavadla, V., Yu, T., Wang, M. H., Woyach, J. A.
Published in HemaSphere (01.06.2022)
Published in HemaSphere (01.06.2022)
Get full text
Journal Article
P1101: PIRTOBRUTINIB, A HIGHLY SELECTIVE, NON‐COVALENT (REVERSIBLE) BTK INHIBITOR IN PREVIOUSLY TREATED MANTLE CELL LYMPHOMA: UPDATED RESULTS FROM THE PHASE 1/2 BRUIN STUDY
Eyre, T. A., Wang, M. L., Shah, N. N., Alencar, A. J., Gerson, J. N., Patel, M. R., Fakhri, B., Vandenberghe, E., Jurczak, W., Tan, X. N., Lewis, K. L., Fenske, T., Wang, Y., Coombs, C. C., Flinn, I., Lewis, D., Le Gouill, S., Gandhi, M., Chay, C., Palomba, M. L., Woyach, J. A., Pagel, J. M., Lamanna, N., Sharman, J. P., Andorsky, D. J., Cohen, J. B., Barve, M. A., Ghia, P., Yin, M., Zinzani, P. L., Ujjani, C., Koh, Y., Izutsu, K., Lech‐Maranda, E., Kherani, J., Tam, C., Sundaram, S., Nair, B., Tsai, D. E., Balbas, M., Mato, A. R., Cheah, C. Y.
Published in HemaSphere (23.06.2022)
Published in HemaSphere (23.06.2022)
Get full text
Journal Article
S147: PIRTOBRUTINIB, A HIGHLY SELECTIVE, NON‐COVALENT (REVERSIBLE) BTK INHIBITOR IN PREVIOUSLY TREATED CLL/SLL: UPDATED RESULTS FROM THE PHASE 1/2 BRUIN STUDY
Mato, A. R., Pagel, J. M., Coombs, C. C., Shah, N. N., Lamanna, N., Munir, T., Lech‐Maranda, E., Eyre, T. A., Woyach, J. A., Wierda, W. G., Cheah, C. Y., Cohen, J. B., Roeker, L. E., Patel, M. R., Fakhri, B., Barve, M. A., Tam, C., Lewis, D., Gerson, J. N., Alencar, A. J., Ujjani, C., Flinn, I., Sundaram, S., Ma, S., Jagadeesh, D., Rhodes, J., Taylor, J., Abdel‐Wahab, O., Ghia, P., Schuster, S. J., Wang, D., Nair, B., Zhu, E., Tsai, D. E., Davids, M. S., Brown, J. R., Jurczak, W.
Published in HemaSphere (01.06.2022)
Published in HemaSphere (01.06.2022)
Get full text
Journal Article
GENOMIC EVOLUTION AND RESISTANCE TO PIRTOBRUTINIB IN COVALENT BTK-INHIBITOR PRE-TREATED CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS: RESULTS FROM THE PHASE I/II BRUIN STUDY
Brown, JR, Woyach, JA, Patel, K, Eyre, TA, Cheah, Cy, Ghia, P, Jurczak, W, Abada, P, Wierda, WG, Presenter, GFPN
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Get full text
Journal Article
Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL
Woyach, Jennifer A, Ruppert, Amy S, Heerema, Nyla A, Zhao, Weiqiang, Booth, Allison M, Ding, Wei, Bartlett, Nancy L, Brander, Danielle M, Barr, Paul M, Rogers, Kerry A, Parikh, Sameer A, Coutre, Steven, Hurria, Arti, Brown, Jennifer R, Lozanski, Gerard, Blachly, James S, Ozer, Hatice G, Major-Elechi, Brittny, Fruth, Briant, Nattam, Sreenivasa, Larson, Richard A, Erba, Harry, Litzow, Mark, Owen, Carolyn, Kuzma, Charles, Abramson, Jeremy S, Little, Richard F, Smith, Scott E, Stone, Richard M, Mandrekar, Sumithra J, Byrd, John C
Published in The New England journal of medicine (27.12.2018)
Published in The New England journal of medicine (27.12.2018)
Get full text
Journal Article
Pirtobrutinib in Post-cBTKi CLL/SLL: ~30 Months Follow-up and Subgroup Analysis With/Without Prior BCL2i from the Phase 1/2 BRUIN Study
Woyach, Jennifer A., Brown, Jennifer R., Ghia, Paolo, Roeker, Lindsey E., Patel, Krish, Eyre, Toby A., Munir, Talha, Lech-Maranda, Ewa, Lamanna, Nicole, Tam, Constantine S., Seymour, John F., Tessoulin, Benoit, Shah, Nirav N., Ujjani, Chaitra S, Fakhri, Bita, Coombs, Catherine C., Flinn, Ian W., Patel, Manish, Nasta, Sunita D., Cohen, Jonathon B., Alencar, Alvaro J., Cheah, Chan Y., Ma, Shuo, Rhodes, Joanna M., Jagadeesh, Deepa, Zinzani, Pier Luigi, Osterborg, Anders, Izutsu, Koji, Tsai, Donald E., Abada, Paolo, Balbas, Minna, Li, Jian, Ruppert, Amy S., Jurczak, Wojciech, Wierda, William G.
Published in BLOOD (02.11.2023)
Published in BLOOD (02.11.2023)
Get full text
Journal Article
Conference Proceeding
Combination therapy with etanercept and rituximab in relapsed CLL/SLL
Woyach, J. A., Lucas, M. S., Heerema, N. A., Moran, M. E., Lucas, D. M., Young, D., Caligiuri, M. A., Lin, T. S., Byrd, J. C.
Published in Journal of clinical oncology (20.05.2008)
Published in Journal of clinical oncology (20.05.2008)
Get full text
Journal Article