An impedance-based approach using human iPSC-derived cardiomyocytes significantly improves in vitro prediction of in vivo cardiotox liabilities
Koci, Bryan, Luerman, Gregory, Duenbostell, Anika, Kettenhofen, Ralf, Bohlen, Heribert, Coyle, Luke, Knight, Brian, Ku, Warren, Volberg, Walter, Woska, Joseph R., Brown, Martha P.
Published in Toxicology and applied pharmacology (15.08.2017)
Published in Toxicology and applied pharmacology (15.08.2017)
Get full text
Journal Article
Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies
Ganesan, Rajkumar, Raymond, Ernest L, Mennerich, Detlev, Woska, Jr, Joseph R, Caviness, Gary, Grimaldi, Christine, Ahlberg, Jennifer, Perez, Rocio, Roberts, Simon, Yang, Danlin, Jerath, Kavita, Truncali, Kristopher, Frego, Lee, Sepulveda, Eliud, Gupta, Priyanka, Brown, Su-Ellen, Howell, Michael D, Canada, Keith A, Kroe-Barrett, Rachel, Fine, Jay S, Singh, Sanjaya, Mbow, M Lamine
Published in mAbs (03.10.2017)
Published in mAbs (03.10.2017)
Get full text
Journal Article
Signal Transduction and Intracellular Trafficking by the Interleukin 36 Receptor
Saha, Siddhartha S., Singh, Divyendu, Raymond, Ernest L., Ganesan, Rajkumar, Caviness, Gary, Grimaldi, Christine, Woska, Joseph R., Mennerich, Detlev, Brown, Su-Ellen, Mbow, M. Lamine, Kao, C. Cheng
Published in The Journal of biological chemistry (25.09.2015)
Published in The Journal of biological chemistry (25.09.2015)
Get full text
Journal Article
SNARE complex‐mediated degranulation in mast cells
Woska, Joseph R., Gillespie, Marc E.
Published in Journal of cellular and molecular medicine (01.04.2012)
Published in Journal of cellular and molecular medicine (01.04.2012)
Get full text
Journal Article
Retrospective analysis of model-based predictivity of human pharmacokinetics for anti-IL-36R monoclonal antibody MAB92 using a rat anti-mouse IL-36R monoclonal antibody and RNA expression data (FANTOM5)
Ahlberg, Jennifer, Giragossian, Craig, Li, Hua, Myzithras, Maria, Raymond, Ernie, Caviness, Gary, Grimaldi, Christine, Brown, Su-Ellen, Perez, Rocio, Yang, Danlin, Kroe-Barrett, Rachel, Joseph, David, Pamulapati, Chandrasena, Coble, Kelly, Ruus, Peter, Woska, Joseph R, Ganesan, Rajkumar, Hansel, Steven, Mbow, M Lamine
Published in mAbs (04.07.2019)
Published in mAbs (04.07.2019)
Get full text
Journal Article
Inhibition of pro-inflammatory cytokine production by the dual p38/JNK2 inhibitor BIRB796 correlates with the inhibition of p38 signaling
Gruenbaum, Lore M., Schwartz, Racheline, Woska, Joseph R., DeLeon, Rodney P., Peet, Gregory W., Warren, Thomas C., Capolino, Alison, Mara, Lisa, Morelock, Maurice M., Shrutkowski, Anthony, Jones, Jessi Wildeson, Pargellis, Christopher A.
Published in Biochemical pharmacology (01.02.2009)
Published in Biochemical pharmacology (01.02.2009)
Get full text
Journal Article
5-Aminomethylbenzimidazoles as potent ITK antagonists
RIETHER, Doris, ZINDELL, Renée, RAYMOND, Ernest L, KHINE, Hnin Hnin, O'SHEA, Kathy, WOSKA, Joseph R, JEANFAVRE, Deborah, SELLATI, Rosemarie, RALPH, Kerry L. M, AHLBERG, Jennifer, LABISSIERE, Gabriel, KASHEM, Mohammed A, KOWALSKI, Jennifer A, PULLEN, Steven S, TAKAHASHI, Hidenori, COOK, Brian N, BENTZIEN, Jörg, DE LOMBAERT, Stéphane, THOMSON, David, KUGLER, Stanley Z, SKOW, Donna, MARTIN, Leslie S
Published in Bioorganic & medicinal chemistry letters (15.03.2009)
Published in Bioorganic & medicinal chemistry letters (15.03.2009)
Get full text
Journal Article
Discovery of potent and selective PKC-θ inhibitors
Cywin, Charles L., Dahmann, Georg, Prokopowicz, Anthony S., Young, Erick R.R., Magolda, Ronald L., Cardozo, Mario G., Cogan, Derek A., DiSalvo, Darren, Ginn, John D., Kashem, Mohammed A., Wolak, John P., Homon, Carol A., Farrell, Thomas M., Grbic, Heather, Hu, Hanbo, Kaplita, Paul V., Liu, Lisa H., Spero, Denice M., Jeanfavre, Deborah D., O’Shea, Kathy M., White, Della M., Woska, Joseph R., Brown, Maryanne L.
Published in Bioorganic & medicinal chemistry letters (2007)
Published in Bioorganic & medicinal chemistry letters (2007)
Get full text
Journal Article
2-Aminobenzimidazoles as potent ITK antagonists: trans-stilbene-like moieties targeting the kinase specificity pocket
Lo, Ho Yin, Bentzien, Jörg, Fleck, Roman W, Pullen, Steven S, Khine, Hnin Hnin, Woska, Jr, Joseph R, Kugler, Stanley Z, Kashem, Mohammed A, Takahashi, Hidenori
Published in Bioorganic & medicinal chemistry (01.12.2008)
Published in Bioorganic & medicinal chemistry (01.12.2008)
Get full text
Journal Article
Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)
MORIARTY, Kevin J, TAKAHASHI, Hidenori, LEI QIAO, RYAN, Declan, DESJARLAIS, Renee, ROBINSON, Darius, WILSON, Matthew, BOBKO, Mark, COOK, Brian N, HO YIN LO, NEMOTO, Peter A, KASHEM, Mohammed A, PULLEN, Steven S, WOLAK, John P, WHITE, André, MAGOLDA, Ronald L, TOMCZUK, Bruce, HNIN HNIN KHINE, SALLATI, Rosemarie H, RAYMOND, Ernest L, WOSKA, Joseph R, JEANFAVRE, Deborah D, ROTH, Gregory P, WINTERS, Michael P
Published in Bioorganic & medicinal chemistry (15.10.2008)
Published in Bioorganic & medicinal chemistry (15.10.2008)
Get full text
Journal Article
5-Aminomethyl-1H-benzimidazoles as orally active inhibitors of inducible T-cell kinase (Itk)
Winters, Michael P, Robinson, Darius J, Khine, Hnin Hnin, Pullen, Steven S, Woska, Jr, Joseph R, Raymond, Ernest L, Sellati, Rosemarie, Cywin, Charles L, Snow, Roger J, Kashem, Mohammed A, Wolak, John P, King, Josephine, Kaplita, Paul V, Liu, Lisa H, Farrell, Thomas M, DesJarlais, Renee, Roth, Gregory P, Takahashi, Hidenori, Moriarty, Kevin J
Published in Bioorganic & medicinal chemistry (15.10.2008)
Published in Bioorganic & medicinal chemistry (15.10.2008)
Get full text
Journal Article
Cutting Edge: A Small Molecule Antagonist of LFA-1-Mediated Cell Adhesion
Kelly, Terence A, Jeanfavre, Deborah D, McNeil, Daniel W, Woska, Joseph R., Jr, Reilly, Patricia L, Mainolfi, Elizabeth A, Kishimoto, Karen M, Nabozny, Gerald H, Zinter, Rosemarie, Bormann, Barbara-Jean, Rothlein, Robert
Published in The Journal of immunology (1950) (15.11.1999)
Published in The Journal of immunology (1950) (15.11.1999)
Get full text
Journal Article
Second-Generation Lymphocyte Function-Associated Antigen-1 Inhibitors: 1H-Imidazo[1,2-α]imidazol-2-one Derivatives
Wu, Jiang-Ping, Emeigh, Jonathan, Gao, Donghong A, Goldberg, Daniel R, Kuzmich, Daniel, Miao, Clara, Potocki, Ian, Qian, Kevin C, Sorcek, Ronald J, Jeanfavre, Deborah D, Kishimoto, Kei, Mainolfi, Elizabeth A, Nabozny, Gerald, Peng, Charline, Reilly, Patricia, Rothlein, Robert, Sellati, Rosemarie H, Woska, Joseph R, Chen, Shirlynn, Gunn, Jocelyn A, O'Brien, Drane, Norris, Stephen H, Kelly, Terence A
Published in Journal of medicinal chemistry (21.10.2004)
Published in Journal of medicinal chemistry (21.10.2004)
Get full text
Journal Article
The determination and correlation of molecular and cellular equilibrium Kd and kinetic koff values for small molecule allosteric antagonists of LFA-1
CAUINESS, Gary O, LABADIA, Mark E, GIBLIN, Patricia A, WOSKA, Joseph R, LAST-BARNEY, Kathleen, JEANFAVRE, Deborah D, MORELOCK, Maurice M
Published in Biochemical pharmacology (30.06.2007)
Published in Biochemical pharmacology (30.06.2007)
Get full text
Journal Article
Broad immunocytochemical localization of the formylpeptide receptor in human organs, tissues, and cells
Becker, E L, Forouhar, F A, Grunnet, M L, Boulay, F, Tardif, M, Bormann, B J, Sodja, D, Ye, R D, Woska, Jr, J R, Murphy, P M
Published in Cell and tissue research (01.04.1998)
Published in Cell and tissue research (01.04.1998)
Get full text
Journal Article
Small molecule LFA-1 antagonists compete with an anti-LFA-1 monoclonal antibody for binding to the CD11a I domain: development of a flow-cytometry-based receptor occupancy assay
Woska, Joseph R., Last-Barney, Kathleen, Rothlein, Robert, Kroe, Rachel R., Reilly, Patricia L., Jeanfavre, Deborah D., Mainolfi, Elizabeth A., Kelly, Terence A., Caviness, Gary O., Fogal, Steven E., Panzenbeck, Maret J., Kishimoto, Takashi K., Giblin, Patricia A.
Published in Journal of immunological methods (01.06.2003)
Published in Journal of immunological methods (01.06.2003)
Get full text
Journal Article
Partners in Science: A Model Cooperative Program Introducing High School Teachers and Students to Leading-Edge Pharmaceutical Science
Woska, Joseph R., Collins, Danielle M., Canney, Brian J., Arcario, Erin L., Reily, Patricia L.
Published in Journal of science education and technology (01.12.2005)
Published in Journal of science education and technology (01.12.2005)
Get full text
Journal Article
The determination and correlation of molecular and cellular equilibrium Kd and kinetic k(off) values for small molecule allosteric antagonists of LFA-1
Caviness, Gary O, Labadia, Mark E, Giblin, Patricia A, Woska, Jr, Joseph R, Last-Barney, Kathleen, Jeanfavre, Deborah D, Morelock, Maurice M
Published in Biochemical pharmacology (30.06.2007)
Get full text
Published in Biochemical pharmacology (30.06.2007)
Journal Article