Studies on the Mechanism of Phosphatidylinositol 3-Kinase Inhibition by Wortmannin and Related Analogs
Norman, Bryan H, Shih, Chuan, Toth, John E, Ray, James E, Dodge, Jeffrey A, Johnson, Doug W, Rutherford, Pamela G, Schultz, Richard M, Worzalla, John F, Vlahos, Chris J
Published in Journal of medicinal chemistry (01.03.1996)
Published in Journal of medicinal chemistry (01.03.1996)
Get full text
Journal Article
Cell cycle modulation by a multitargeted antifolate, LY231514, increases the cytotoxicity and antitumor activity of gemcitabine in HT29 colon carcinoma
TONKINSON, J. L, WORZALLA, J. F, TENG, C.-H, MENDELSOHN, L. G
Published in Cancer research (Chicago, Ill.) (01.08.1999)
Get full text
Published in Cancer research (Chicago, Ill.) (01.08.1999)
Journal Article
Synthesis and biological activity of acyclic analogs of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid
Shih, Chuan, Gossett, Lynn S, Worzalla, John F, Rinzel, Sharon M, Grindey, Gerald B, Harrington, Philip M, Taylor, Edward C
Published in Journal of medicinal chemistry (01.03.1992)
Published in Journal of medicinal chemistry (01.03.1992)
Get full text
Journal Article
Sulfonimidamide Analogs of Oncolytic Sulfonylureas † ,1
Toth, John E, Grindey, Gerald B, Ehlhardt, William J, Ray, James E, Boder, George B, Bewley, Jesse R, Klingerman, Kim K, Gates, Susan B, Rinzel, Sharon M, Schultz, Richard M, Weir, Leonard C, Worzalla, John F
Published in Journal of medicinal chemistry (14.03.1997)
Published in Journal of medicinal chemistry (14.03.1997)
Get full text
Journal Article
Comparison of metabolism and toxicity to the structure of the anticancer agent sulofenur and related sulfonylureas
Ehlhardt, William J, Woodland, Joseph M, Worzalla, John F, Bewley, Jesse R, Grindey, Gerald B, Todd, Glen C, Toth, John E, Howbert, J. Jeffry
Published in Chemical research in toxicology (01.09.1992)
Published in Chemical research in toxicology (01.09.1992)
Get full text
Journal Article
Metabolism of hexamethylmelamine-ring-14C in rats and man
Worzalla, J F, Kaiman, B D, Johnson, B M, Ramirez, G, Bryan, G T
Published in Cancer research (Chicago, Ill.) (01.10.1974)
Get full text
Published in Cancer research (Chicago, Ill.) (01.10.1974)
Journal Article
N-demethylation of the antineoplastic agent hexamethylmelamine by rats and man
Worzalla, J F, Johnson, B M, Ramirez, G, Bryan, G T
Published in Cancer research (Chicago, Ill.) (01.11.1973)
Get full text
Published in Cancer research (Chicago, Ill.) (01.11.1973)
Journal Article
Sulfonimidamide analogs of oncolytic sulfonylureas
Toth, JE, Grindey, GB, Ehlhardt, WJ, Ray, JE, Boder, GB, Bewley, Klingerman, KK, Gates, SB, Rinzel, SM, Schultz, RM, Weir, LC, Worzalla, JF
Published in Journal of medicinal chemistry (14.03.1997)
Published in Journal of medicinal chemistry (14.03.1997)
Get full text
Journal Article
Synthesis and biological evaluation of novel cryptophycin analogs with modification in the β-alanine region
Shih, Chuan, Gossett, Lynn S., Gruber, Joseph M., Grossman, C.Sue, Andis, Sherri L., Schultz, Richard M., Worzalla, John F., Corbett, Tom H., Metz, James T.
Published in Bioorganic & medicinal chemistry letters (04.01.1999)
Published in Bioorganic & medicinal chemistry letters (04.01.1999)
Get full text
Journal Article
Whole-body disposition and polyglutamate distribution of the GAR formyltransferase inhibitors LY309887 and lometrexol in mice: effect of low-folate diet
Habeck, Lillian L, Chay, Sylvia H., Pohland, Raymond C., Worzalla, John F., Shih, Chuan, Mendelsohn, Laurane G.
Published in Cancer chemotherapy and pharmacology (09.12.1997)
Published in Cancer chemotherapy and pharmacology (09.12.1997)
Get full text
Journal Article
Characterization of folate receptor from normal and neoplastic murine tissue: influence of dietary folate on folate receptor expression
GATES, S. B, MENDELSOHN, L. G, SHACKELFORD, K. A, HABECK, L. L, KURSAR, J. D, GOSSETT, L. S, WORZALLA, J. F, SHIH, C, GRINDEY, G. B
Published in Clinical cancer research (01.07.1996)
Get full text
Published in Clinical cancer research (01.07.1996)
Journal Article
The synthesis and biological activity of a series of 2,4-diaminopyrido[2,3- D]pyrimidine based antifolates as antineoplastic and antiarthritic agents
Gossett, Lynn S., Habeck, Lillian L., Shackelford, Katherine A., Mendelsohn, Laurane G., Gates, Susan B., Worzalla, John F., Self, Tracy D., Theobald, Karla S., Andis, Sherri L., Schultz, Richard M., Shih, Chuan
Published in Bioorganic & medicinal chemistry letters (04.01.1999)
Published in Bioorganic & medicinal chemistry letters (04.01.1999)
Get full text
Journal Article
Synthesis and biological evaluation of a new series of dihydrofolate reductase inhibitors based on the 4-(2,6-diamino-5-pyrimidinyl)alkyl-L-glutamic acid structure
Gossett, Lynn S., Habeck, Lillian L., Gates, Susan B., Andis, Sherri L., Worzalla, John F., Schultz, Richard M., Mendelsonn, Laurane G., Kohler, William, Ratnam, Manohar, Grindey, Gerald B., Shih, Chuan
Published in Bioorganic & medicinal chemistry letters (20.02.1996)
Published in Bioorganic & medicinal chemistry letters (20.02.1996)
Get full text
Journal Article