LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth
Liu, Ling, Zeng, Wei, Wortinger, Mark A, Yan, S Betty, Cornwell, Paul, Peek, Victoria L, Stephens, Jennifer R, Tetreault, Jonathan W, Xia, Jinqi, Manro, Jason R, Credille, Kelly M, Ballard, Darryl W, Brown-Augsburger, Patricia, Wacheck, Volker, Chow, Chi-Kin, Huang, Lihua, Wang, Yong, Denning, Irene, Davies, Julian, Tang, Ying, Vaillancourt, Peter, Lu, Jirong
Published in Clinical cancer research (01.12.2014)
Published in Clinical cancer research (01.12.2014)
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Journal Article
Immunohistochemical application of a highly sensitive and specific murine monoclonal antibody recognising the extracellular domain of the human hepatocyte growth factor receptor (MET)
Gruver, Aaron M, Liu, Ling, Vaillancourt, Peter, Yan, Sau-Chi B, Cook, Joel D, Roseberry Baker, Jessica A, Felke, Erin M, Lacy, Megan E, Marchal, Christophe C, Szpurka, Hadrian, Holzer, Timothy R., Rhoads, Emily K, Zeng, Wei, Wortinger, Mark A, Lu, Jirong, Chow, Chi-kin, Denning, Irene J, Beuerlein, Gregory, Davies, Julian, Hanson, Jeff C, Credille, Kelly M, Wijayawardana, Sameera R, Schade, Andrew E
Published in Histopathology (01.12.2014)
Published in Histopathology (01.12.2014)
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Journal Article
Fas ligand‐induced murine pulmonary inflammation is reduced by a stable decoy receptor 3 analogue
Wortinger, Mark A., Foley, Joseph W., Larocque, Patrick, Witcher, Derrick R., Lahn, Michael, Jakubowski, Joseph A., Glasebrook, Andrew, Song, Ho Yeong
Published in Immunology (01.10.2003)
Published in Immunology (01.10.2003)
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Journal Article
Morphological adaptation and inhibition of cell division during stationary phase in Caulobacter crescentus
Wortinger, Mark A., Quardokus, Ellen M., Brun, Yves V.
Published in Molecular microbiology (01.08.1998)
Published in Molecular microbiology (01.08.1998)
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Journal Article
GITR 길항제 및 그의 사용 방법
CAIN PAUL FRANCIS, LEE STACEY LYNN, WORTINGER MARK ANDREW, VERDINO PETRA, LACERTE MELINDA ANN
Year of Publication 22.08.2023
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Year of Publication 22.08.2023
Patent
Abstract 5465: LY2875358, a bivalent MET antibody with anti-tumor activity through blocking HGF as well as inducing degradation of MET, differentiates from a one-armed 5D5 MET antibody
Zeng, Wei, Peek, Victoria, Wortinger, Mark, Tetreault, Jonathan, Xia, Jinqi, Stephens, Jennifer, Credille, Kelly, Ballard, Darryl, Brown-Augsburger, Trish, Lu, Jirong, Chow, Chi-Kin, Vaillancourt, Peter, Tang, Ying, Yan, Sau-Chi B., Liu, Ling
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Abstract 2734: c-Met antibody LY2875358 (LA480) shows differential antitumor effects in non-small cell lung cancer
Zeng, Wei, Yan, Lei, Peek, Victoria, Wortinger, Mark, Tetreault, Jonathan, Xia, Jinqi, Chow, Chi-Kin, Manro, Jason R., Stephens, Jennifer R., Weir, Spring N., Tang, Ying, Vaillancourt, Peter, Lu, Jirong, Yan, Betty S., Liu, Ling
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Abstract 2738: c-Met antibody LY2875358 (LA480) has pre-clinical enhanced efficacy with gastric cancer standard-of-care in vitro and in vivo
Wortinger, Mark A., Peek, Victoria, Zeng, Wei, Yan, Lei, Tetreault, Jonathan, Xia, Jinqi, Jirong, Lu, Chow, Chi-Kin, Manro, Jason R., Stephens, Jennifer R., Merzoug, Farhana, Vaillancourt, Peter, Yan, S. Betty, Liu, Ling
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Abstract 2430: Gastric cancer cell lines with c-Met gene amplification are sensitive to growth inhibition by the bivalent c-Met antibody LA480
Tetreault, Jonathan, Xia, Jinqi, Zeng, Wei, Wortinger, Mark, Cunningham, Jason, Feroze, Farhana Mohammed, Yu, Kun, Chow, Chi-Kin, Lu, Jirong, Denning, Irene, Vaillancourt, Peter, Davies, Julian, Liu, Ling
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Abstract 695: LA480, a c-Met antibody with neutralization and internalization properties, inhibits HGF-dependent and HGF-independent c-Met pathway activation and tumor growth
Wortinger, Mark A., Zeng, Wei, Yang, Wei Jennifer, Peek, Victoria, Yan, Lei, Lu, Jirong, Chow, Chi-Kin, Vaillancourt, Peter, Davies, Julian, Denning, Irene, Weir, Spring, Wooldridge, James, Liu, Ling
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Abstract 2583: LA480, a bivalent humanized c-Met monoclonal antibody, inhibits tumor growth without eliciting significant agonist activity
Zeng, Wei, Wortinger, Mark, Yang, Wei Jennifer, Peek, Victoria, Yan, Lei, Lu, Jirong, Chow, Chi-Kin, Vaillancourt, Peter, Davies, Julian, Denning, Irene, Weir, Spring, McClure, Don, Chintharlapalli, Sudhakar, Liu, Ling
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
C-MET ANTIBODIES
LU JIRONG, DAVIES JULIAN, ZENG WEI, VAILLANCOURT PETER EDWARD, LIU LING, WORTINGER MARK ANDREW
Year of Publication 30.06.2011
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Year of Publication 30.06.2011
Patent
GITR ANTAGONISTS AND METHODS OF USING THE SAME
WORTINGER, Mark Andrew, LACERTE, Melinda Ann, LEE, Stacey Lynn, VERDINO, Petra, CAIN, Paul Francis
Year of Publication 16.05.2024
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Year of Publication 16.05.2024
Patent
GITR antagonists and methods of using the same
Cain, Paul Francis, Verdino, Petra, Lacerte, Melinda Ann, Wortinger, Mark Andrew, Lee, Stacey Lynn
Year of Publication 02.01.2024
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Year of Publication 02.01.2024
Patent
GITR ANTAGONISTS AND METHODS OF USING THE SAME
WORTINGER, Mark Andrew, LACERTE, Melinda Ann, LEE, Stacey Lynn, VERDINO, Petra, CAIN, Paul Francis
Year of Publication 13.12.2023
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Year of Publication 13.12.2023
Patent
GITR ANTAGONISTS AND METHODS OF USING THE SAME
WORTINGER, Mark Andrew, LACERTE, Melinda Ann, LEE, Stacey Lynn, VERDINO, Petra, CAIN, Paul Francis
Year of Publication 20.07.2023
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Year of Publication 20.07.2023
Patent
GITR ANTAGONISTS AND METHODS OF USING THE SAME
WORTINGER, Mark Andrew, LACERTE, Melinda Ann, LEE, Stacey Lynn, VERDINO, Petra, CAIN, Paul Francis
Year of Publication 11.08.2022
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Year of Publication 11.08.2022
Patent
GITR ANTAGONISTS AND METHODS OF USING THE SAME
WORTINGER, Mark Andrew, LACERTE, Melinda Ann, LEE, Stacey Lynn, VERDINO, Petra, CAIN, Paul Francis
Year of Publication 11.08.2022
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Year of Publication 11.08.2022
Patent
GITR ANTAGONISTS AND METHODS OF USING THE SAME
LEE, STACEY LYNN, VERDINO, PETRA, LACERTE, MELINDA ANN, WORTINGER, MARK ANDREW, CAIN, PAUL FRANCIS
Year of Publication 11.08.2022
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Year of Publication 11.08.2022
Patent