The genetics revolution in rheumatology: large scale genomic arrays and genetic mapping
Eyre, Stephen, Orozco, Gisela, Worthington, Jane
Published in Nature reviews. Rheumatology (01.07.2017)
Published in Nature reviews. Rheumatology (01.07.2017)
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Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
Raychaudhuri, Soumya, Sandor, Cynthia, Stahl, Eli A, Freudenberg, Jan, Lee, Hye-Soon, Jia, Xiaoming, Alfredsson, Lars, Padyukov, Leonid, Klareskog, Lars, Worthington, Jane, Siminovitch, Katherine A, Bae, Sang-Cheol, Plenge, Robert M, Gregersen, Peter K, de Bakker, Paul I W
Published in Nature genetics (01.03.2012)
Published in Nature genetics (01.03.2012)
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Bayesian refinement of association signals for 14 loci in 3 common diseases
Maller, Julian B, McVean, Gilean, Byrnes, Jake, Vukcevic, Damjan, Palin, Kimmo, Su, Zhan, Howson, Joanna M M, Auton, Adam, Myers, Simon, Morris, Andrew, Pirinen, Matti, Brown, Matthew A, Burton, Paul R, Caulfield, Mark J, Compston, Alastair, Farrall, Martin, Hall, Alistair S, Hattersley, Andrew T, Hill, Adrian V S, Mathew, Christopher G, Pembrey, Marcus, Satsangi, Jack, Stratton, Michael R, Worthington, Jane, Craddock, Nick, Hurles, Matthew, Ouwehand, Willem, Parkes, Miles, Rahman, Nazneen, Duncanson, Audrey, Todd, John A, Kwiatkowski, Dominic P, Samani, Nilesh J, Gough, Stephen C L, McCarthy, Mark I, Deloukas, Panagiotis, Donnelly, Peter
Published in Nature genetics (01.12.2012)
Published in Nature genetics (01.12.2012)
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Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients
Viatte, Sebastien, Plant, Darren, Bowes, John, Lunt, Mark, Eyre, Stephen, Barton, Anne, Worthington, Jane
Published in Annals of the rheumatic diseases (01.12.2012)
Published in Annals of the rheumatic diseases (01.12.2012)
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Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes
Westra, Harm-Jan, Martínez-Bonet, Marta, Onengut-Gumuscu, Suna, Lee, Annette, Luo, Yang, Teslovich, Nikola, Worthington, Jane, Martin, Javier, Huizinga, Tom, Klareskog, Lars, Rantapaa-Dahlqvist, Solbritt, Chen, Wei-Min, Quinlan, Aaron, Todd, John A., Eyre, Steve, Nigrovic, Peter A., Gregersen, Peter K., Rich, Stephen S., Raychaudhuri, Soumya
Published in Nature genetics (01.10.2018)
Published in Nature genetics (01.10.2018)
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Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls
Fortune, Mary D, Guo, Hui, Burren, Oliver, Schofield, Ellen, Walker, Neil M, Ban, Maria, Sawcer, Stephen J, Bowes, John, Worthington, Jane, Barton, Anne, Eyre, Steve, Todd, John A, Wallace, Chris
Published in Nature genetics (01.07.2015)
Published in Nature genetics (01.07.2015)
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Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins
Webster, Amy P, Plant, Darren, Ecker, Simone, Zufferey, Flore, Bell, Jordana T, Feber, Andrew, Paul, Dirk S, Beck, Stephan, Barton, Anne, Williams, Frances M K, Worthington, Jane
Published in Genome medicine (04.09.2018)
Published in Genome medicine (04.09.2018)
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A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci
Liu, Ying, Helms, Cynthia, Liao, Wilson, Zaba, Lisa C, Duan, Shenghui, Gardner, Jennifer, Wise, Carol, Miner, Andrew, Malloy, M J, Pullinger, Clive R, Kane, John P, Saccone, Scott, Worthington, Jane, Bruce, Ian, Kwok, Pui-Yan, Menter, Alan, Krueger, James, Barton, Anne, Saccone, Nancy L, Bowcock, Anne M
Published in PLoS genetics (01.04.2008)
Published in PLoS genetics (01.04.2008)
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Chromatin interactions reveal novel gene targets for drug repositioning in rheumatic diseases
Martin, Paul, Ding, James, Duffus, Kate, Gaddi, Vasanthi Priyadarshini, McGovern, Amanda, Ray-Jones, Helen, Yarwood, Annie, Worthington, Jane, Barton, Anne, Orozco, Gisela
Published in Annals of the rheumatic diseases (01.08.2019)
Published in Annals of the rheumatic diseases (01.08.2019)
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Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity
Han, Buhm, Diogo, Dorothée, Eyre, Steve, Kallberg, Henrik, Zhernakova, Alexandra, Bowes, John, Padyukov, Leonid, Okada, Yukinori, González-Gay, Miguel A., Rantapää-Dahlqvist, Solbritt, Martin, Javier, Huizinga, Tom W.J., Plenge, Robert M., Worthington, Jane, Gregersen, Peter K., Klareskog, Lars, de Bakker, Paul I.W., Raychaudhuri, Soumya
Published in American journal of human genetics (03.04.2014)
Published in American journal of human genetics (03.04.2014)
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Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus
Orozco, Gisela, Eyre, Steve, Hinks, Anne, Bowes, John, Morgan, Ann W, Wilson, Anthony G, Wordsworth, Paul, Steer, Sophia, Hocking, Lynne, Thomson, Wendy, Worthington, Jane, Barton, Anne
Published in Annals of the rheumatic diseases (01.03.2011)
Published in Annals of the rheumatic diseases (01.03.2011)
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Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C
Martin, Paul, McGovern, Amanda, Massey, Jonathan, Schoenfelder, Stefan, Duffus, Kate, Yarwood, Annie, Barton, Anne, Worthington, Jane, Fraser, Peter, Eyre, Stephen, Orozco, Gisela
Published in PloS one (18.11.2016)
Published in PloS one (18.11.2016)
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Quantifying missing heritability at known GWAS loci
Gusev, Alexander, Bhatia, Gaurav, Zaitlen, Noah, Vilhjalmsson, Bjarni J, Diogo, Dorothée, Stahl, Eli A, Gregersen, Peter K, Worthington, Jane, Klareskog, Lars, Raychaudhuri, Soumya, Plenge, Robert M, Pasaniuc, Bogdan, Price, Alkes L
Published in PLoS genetics (01.12.2013)
Published in PLoS genetics (01.12.2013)
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A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases
Han, Buhm, Pouget, Jennie G, Slowikowski, Kamil, Stahl, Eli, Lee, Cue Hyunkyu, Diogo, Dorothee, Hu, Xinli, Park, Yu Rang, Kim, Eunji, Gregersen, Peter K, Dahlqvist, Solbritt Rantapää, Worthington, Jane, Martin, Javier, Eyre, Steve, Klareskog, Lars, Huizinga, Tom, Chen, Wei-Min, Onengut-Gumuscu, Suna, Rich, Stephen S, Wray, Naomi R, Raychaudhuri, Soumya
Published in Nature genetics (01.07.2016)
Published in Nature genetics (01.07.2016)
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Novel Rheumatoid Arthritis Susceptibility Locus at 22q12 Identified in an Extended UK Genome‐Wide Association Study
Orozco, Gisela, Viatte, Sebastien, Bowes, John, Martin, Paul, Wilson, Anthony G., Morgan, Ann W., Steer, Sophia, Wordsworth, Paul, Hocking, Lynne J., Barton, Anne, Worthington, Jane, Eyre, Stephen
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2014)
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Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking
Scott, Ian C, Seegobin, Seth D, Steer, Sophia, Tan, Rachael, Forabosco, Paola, Hinks, Anne, Eyre, Stephen, Morgan, Ann W, Wilson, Anthony G, Hocking, Lynne J, Wordsworth, Paul, Barton, Anne, Worthington, Jane, Cope, Andrew P, Lewis, Cathryn M
Published in PLoS genetics (01.09.2013)
Published in PLoS genetics (01.09.2013)
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Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility
Barton, Anne, Thomson, Wendy, Ke, Xiayi, Eyre, Steve, Hinks, Anne, Bowes, John, Gibbons, Laura, Plant, Darren, Wilson, Anthony G., Marinou, Ioanna, Morgan, Ann, Emery, Paul, Steer, Sophia, Hocking, Lynne, Reid, David M., Wordsworth, Paul, Harrison, Pille, Worthington, Jane
Published in Human molecular genetics (01.08.2008)
Published in Human molecular genetics (01.08.2008)
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