Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
Dong, Zhiwei, Shanmughapriya, Santhanam, Tomar, Dhanendra, Siddiqui, Naveed, Lynch, Solomon, Nemani, Neeharika, Breves, Sarah L., Zhang, Xueqian, Tripathi, Aparna, Palaniappan, Palaniappan, Riitano, Massimo F., Worth, Alison M., Seelam, Ajay, Carvalho, Edmund, Subbiah, Ramasamy, Jaña, Fabián, Soboloff, Jonathan, Peng, Yizhi, Cheung, Joseph Y., Joseph, Suresh K., Caplan, Jeffrey, Rajan, Sudarsan, Stathopulos, Peter B., Madesh, Muniswamy
Published in Molecular cell (16.03.2017)
Published in Molecular cell (16.03.2017)
Get full text
Journal Article
MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress
Nemani, Neeharika, Carvalho, Edmund, Tomar, Dhanendra, Dong, Zhiwei, Ketschek, Andrea, Breves, Sarah L., Jaña, Fabián, Worth, Alison M., Heffler, Julie, Palaniappan, Palaniappan, Tripathi, Aparna, Subbiah, Ramasamy, Riitano, Massimo F., Seelam, Ajay, Manfred, Thomas, Itoh, Kie, Meng, Shuxia, Sesaki, Hiromi, Craigen, William J., Rajan, Sudarsan, Shanmughapriya, Santhanam, Caplan, Jeffrey, Prosser, Benjamin L., Gill, Donald L., Stathopulos, Peter B., Gallo, Gianluca, Chan, David C., Mishra, Prashant, Madesh, Muniswamy
Published in Cell reports (Cambridge) (24.04.2018)
Published in Cell reports (Cambridge) (24.04.2018)
Get full text
Journal Article
Methylene Blue Counteracts H 2 S-Induced Cardiac Ion Channel Dysfunction and ATP Reduction
Cheung, Joseph Y, Wang, JuFang, Zhang, Xue-Qian, Song, Jianliang, Davidyock, John M, Prado, Fabian Jana, Shanmughapriya, Santhanam, Worth, Alison M, Madesh, Muniswamy, Judenherc-Haouzi, Annick, Haouzi, Philippe
Published in Cardiovascular toxicology (01.10.2018)
Published in Cardiovascular toxicology (01.10.2018)
Get full text
Journal Article
Methylene Blue Counteracts H2S-Induced Cardiac Ion Channel Dysfunction and ATP Reduction
Cheung, Joseph Y., Wang, JuFang, Zhang, Xue-Qian, Song, Jianliang, Davidyock, John M., Prado, Fabian Jana, Shanmughapriya, Santhanam, Worth, Alison M., Madesh, Muniswamy, Judenherc-Haouzi, Annick, Haouzi, Philippe
Published in Cardiovascular toxicology (01.10.2018)
Published in Cardiovascular toxicology (01.10.2018)
Get full text
Journal Article
1514 In vivo CAR-M: redirecting endogenous myeloid cells with mRNA for cancer immunotherapy
Varghese, Bindu, Mori, Simone, Pierini, Stefano, Bagashev, Asen, Ohtani, Yumi, Gabbasov, Rashid, Ross, Kayleigh, Huang, Shuo, Bona, Amanda, Merdiana, Sherly, Slovik, Kate, Worth, Alison, Nagar, Karan, Saporito, Robert, Shaw, Lauren, Ball, Michael, Qureshi, Rehman, Minutolo, Nicholas, Tosh, Kevin, Lee, Claudia, Lukacs, Christine, Guey, Lin, Klichinsky, Michael, Condamine, Thomas
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
Get full text
Journal Article
Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation
Tomar, Dhanendra, Jaña, Fabián, Dong, Zhiwei, Quinn, William J., Jadiya, Pooja, Breves, Sarah L., Daw, Cassidy C., Srikantan, Subramanya, Shanmughapriya, Santhanam, Nemani, Neeharika, Carvalho, Edmund, Tripathi, Aparna, Worth, Alison M., Zhang, Xueqian, Razmpour, Roshanak, Seelam, Ajay, Rhode, Stephen, Mehta, Anuj V., Murray, Michael, Slade, Daniel, Ramirez, Servio H., Mishra, Prashant, Gerhard, Glenn S., Caplan, Jeffrey, Norton, Luke, Sharma, Kumar, Rajan, Sudarsan, Balciunas, Darius, Wijesinghe, Dayanjan S., Ahima, Rexford S., Baur, Joseph A., Madesh, Muniswamy
Published in Cell reports (Cambridge) (26.03.2019)
Published in Cell reports (Cambridge) (26.03.2019)
Get full text
Journal Article
139 Chimeric antigen receptor macrophages (CAR-M) elicit a systemic anti-tumor immune response and synergize with PD1 blockade in immunocompetent mouse models of HER2+ solid tumors
Pierini, Stefano, Klichinsky, Michael, Gabbasov, Rashid, Worth, Alison, Ramos, Ilyssa, Blumenthal, Daniel, Gabitova, Linara, Abramson, Sascha, Condamine, Thomas, Ball, Michael, Ohtani, Yumi
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
Get full text
Journal Article
The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer
Mirji, Gauri, Worth, Alison, Bhat, Sajad Ahmad, El Sayed, Mohamed, Kannan, Toshitha, Goldman, Aaron R, Tang, Hsin-Yao, Liu, Qin, Auslander, Noam, Dang, Chi V, Abdel-Mohsen, Mohamed, Kossenkov, Andrew, Stanger, Ben Z, Shinde, Rahul S
Published in Science immunology (09.09.2022)
Published in Science immunology (09.09.2022)
Get more information
Journal Article
Alterations in bone metabolites with age in C57BL/6 mice model
Patel, Dhara, Lee, Tae Jin, Kumar, Sandeep, Vyavahare, Sagar, Worth, Alison, Hill, William D., Hamrick, Mark, Isales, Carlos M., Shinde, Rahul S., Fulzele, Sadanand
Published in Biogerontology (Dordrecht) (01.10.2022)
Published in Biogerontology (Dordrecht) (01.10.2022)
Get full text
Journal Article
Abstract 4053: A mesothelin targeting chimeric antigen receptor macrophage (CAR-M) for solid tumor immunotherapy: pre-clinical development of CT-1119
Anderson, Nicholas R., Shah, Brinda, Worth, Alison, Gabbasov, Rashid, Menchel, Brett, Ciccaglione, Kerri, Blumenthal, Daniel, Pierini, Stefano, DeLong, Sabrina Ceeraz, Abramson, Sascha, Condamine, Thomas, Klichinsky, Michael
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
Abstract 2112: Chimeric antigen receptor macrophages (CAR-M) sensitize solid tumors to anti-PD1 immunotherapy
Pierini, Stefano, Gabbasov, Rashid, Worth, Alison, Ramos, Ilyssa, Blumenthal, Daniel, Ohtani, Yumi, Gabitova, Linara, Ball, Michael, Abramson, Sascha, Condamine, Thomas, Klichinsky, Michael
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
Abstract C023: A microbiome-produced metabolite drives immunostimulatory macrophages and boosts response to immune checkpoint inhibitors in pancreatic cancer
Mirji, Gauri, Worth, Alison, Bhat, Sajad, Sayed, Mohamed, Kannan, Toshitha, Goldman, Aaron, Tang, Hsin-Yao, Liu, Qin, Auslander, Noam, Dang, Chi, Abdel-Mohsen, Mohamed, Kossenkov, Andrew, Stanger, Ben, Shinde, Rahul
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Get full text
Journal Article
1307 The microbiome-derived metabolite TMAO drives immune activation and boosts response to immune checkpoint blockade in pancreatic cancer
Mirji, Gauri, Worth, Alison, Bhat, Sajad, Mohamed El Sayed, Kannan, Toshitha, Goldman, Aaron, Hsin Yao Tang, Liu, Qin, Auslander, Noam, Dang, Chi, Abdel-Mohsen, Mohamed, Kossenkov, Andrew, Stanger, Ben, Shinde, Rahul
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
Get full text
Journal Article
Blockade of MCU-Mediated Ca 2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation
Tomar, Dhanendra, Jaña, Fabián, Dong, Zhiwei, Quinn, 3rd, William J, Jadiya, Pooja, Breves, Sarah L, Daw, Cassidy C, Srikantan, Subramanya, Shanmughapriya, Santhanam, Nemani, Neeharika, Carvalho, Edmund, Tripathi, Aparna, Worth, Alison M, Zhang, Xueqian, Razmpour, Roshanak, Seelam, Ajay, Rhode, Stephen, Mehta, Anuj V, Murray, Michael, Slade, Daniel, Ramirez, Servio H, Mishra, Prashant, Gerhard, Glenn S, Caplan, Jeffrey, Norton, Luke, Sharma, Kumar, Rajan, Sudarsan, Balciunas, Darius, Wijesinghe, Dayanjan S, Ahima, Rexford S, Baur, Joseph A, Madesh, Muniswamy
Published in Cell reports (Cambridge) (26.03.2019)
Get full text
Published in Cell reports (Cambridge) (26.03.2019)
Journal Article
MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca 2+ Stress
Nemani, Neeharika, Carvalho, Edmund, Tomar, Dhanendra, Dong, Zhiwei, Ketschek, Andrea, Breves, Sarah L, Jaña, Fabián, Worth, Alison M, Heffler, Julie, Palaniappan, Palaniappan, Tripathi, Aparna, Subbiah, Ramasamy, Riitano, Massimo F, Seelam, Ajay, Manfred, Thomas, Itoh, Kie, Meng, Shuxia, Sesaki, Hiromi, Craigen, William J, Rajan, Sudarsan, Shanmughapriya, Santhanam, Caplan, Jeffrey, Prosser, Benjamin L, Gill, Donald L, Stathopulos, Peter B, Gallo, Gianluca, Chan, David C, Mishra, Prashant, Madesh, Muniswamy
Published in Cell reports (Cambridge) (24.04.2018)
Get full text
Published in Cell reports (Cambridge) (24.04.2018)
Journal Article
Mitochondrial Ca 2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
Dong, Zhiwei, Shanmughapriya, Santhanam, Tomar, Dhanendra, Siddiqui, Naveed, Lynch, Solomon, Nemani, Neeharika, Breves, Sarah L, Zhang, Xueqian, Tripathi, Aparna, Palaniappan, Palaniappan, Riitano, Massimo F, Worth, Alison M, Seelam, Ajay, Carvalho, Edmund, Subbiah, Ramasamy, Jaña, Fabián, Soboloff, Jonathan, Peng, Yizhi, Cheung, Joseph Y, Joseph, Suresh K, Caplan, Jeffrey, Rajan, Sudarsan, Stathopulos, Peter B, Madesh, Muniswamy
Published in Molecular cell (16.03.2017)
Get full text
Published in Molecular cell (16.03.2017)
Journal Article