Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling
Hayakawa, Yoku, Sakitani, Kosuke, Konishi, Mitsuru, Asfaha, Samuel, Niikura, Ryota, Tomita, Hiroyuki, Renz, Bernhard W., Tailor, Yagnesh, Macchini, Marina, Middelhoff, Moritz, Jiang, Zhengyu, Tanaka, Takayuki, Dubeykovskaya, Zinaida A., Kim, Woosook, Chen, Xiaowei, Urbanska, Aleksandra M., Nagar, Karan, Westphalen, Christoph B., Quante, Michael, Lin, Chyuan-Sheng, Gershon, Michael D., Hara, Akira, Zhao, Chun-Mei, Chen, Duan, Worthley, Daniel L., Koike, Kazuhiko, Wang, Timothy C.
Published in Cancer cell (09.01.2017)
Published in Cancer cell (09.01.2017)
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Journal Article
Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche
Middelhoff, Moritz, Nienhüser, Henrik, Valenti, Giovanni, Maurer, H. Carlo, Hayakawa, Yoku, Takahashi, Ryota, Kim, Woosook, Jiang, Zhengyu, Malagola, Ermanno, Cuti, Krystle, Tailor, Yagnesh, Zamechek, Leah B., Renz, Bernhard W., Quante, Michael, Yan, Kelley S., Wang, Timothy C.
Published in Nature communications (08.01.2020)
Published in Nature communications (08.01.2020)
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Journal Article
PD-1 Signaling Promotes Tumor-Infiltrating Myeloid-Derived Suppressor Cells and Gastric Tumorigenesis in Mice
Kim, Woosook, Chu, Timothy H., Nienhüser, Henrik, Jiang, Zhengyu, Del Portillo, Armando, Remotti, Helen E., White, Ruth A., Hayakawa, Yoku, Tomita, Hiroyuki, Fox, James G., Drake, Charles G., Wang, Timothy C.
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2021)
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Journal Article
Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche
Hayakawa, Yoku, Ariyama, Hiroshi, Stancikova, Jitka, Sakitani, Kosuke, Asfaha, Samuel, Renz, Bernhard W., Dubeykovskaya, Zinaida A., Shibata, Wataru, Wang, Hongshan, Westphalen, Christoph B., Chen, Xiaowei, Takemoto, Yoshihiro, Kim, Woosook, Khurana, Shradha S., Tailor, Yagnesh, Nagar, Karan, Tomita, Hiroyuki, Hara, Akira, Sepulveda, Antonia R., Setlik, Wanda, Gershon, Michael D., Saha, Subhrajit, Ding, Lei, Shen, Zeli, Fox, James G., Friedman, Richard A., Konieczny, Stephen F., Worthley, Daniel L., Korinek, Vladimir, Wang, Timothy C.
Published in Cancer cell (14.12.2015)
Published in Cancer cell (14.12.2015)
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Journal Article
Mist1+ gastric isthmus stem cells are regulated by Wnt5a and expand in response to injury and inflammation in mice
Nienhüser, Henrik, Kim, Woosook, Malagola, Ermanno, Ruan, Tuo, Valenti, Giovanni, Middelhoff, Moritz, Bass, Adam, Der, Channing J, Hayakawa, Yoku, Wang, Timothy C
Published in Gut (01.04.2021)
Published in Gut (01.04.2021)
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Journal Article
RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation
Kim, Woosook, Barren, David A., San Martin, Rebeca, Chan, Keith S., Tran, Linda L., Yang, Feng, Ressler, Steven J., Rowley, David R.
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2014)
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Journal Article
Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis
Chang, Wenju, Wang, Hongshan, Kim, Woosook, Liu, Yang, Deng, Huan, Liu, Haibo, Jiang, Zhengyu, Niu, Zhengchuan, Sheng, Weiwei, Nápoles, Osmel Companioni, Sun, Yihong, Xu, Jianmin, Sepulveda, Antonia, Hayakawa, Yoku, Bass, Adam J., Wang, Timothy C.
Published in Cell stem cell (07.05.2020)
Published in Cell stem cell (07.05.2020)
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Journal Article
BHLHA15-Positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice
Hayakawa, Yoku, Tsuboi, Mayo, Asfaha, Samuel, Kinoshita, Hiroto, Niikura, Ryota, Konishi, Mitsuru, Hata, Masahiro, Oya, Yukiko, Kim, Woosook, Middelhoff, Moritz, Hikiba, Yohko, Higashijima, Naoko, Ihara, Sozaburo, Ushiku, Tetsuo, Fukayama, Masashi, Tailor, Yagnesh, Hirata, Yoshihiro, Guha, Chandan, Yan, Kelley S., Koike, Kazuhiko, Wang, Timothy C.
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2019)
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Journal Article
Hypergastrinemia Expands Gastric ECL Cells Through CCK2R+ Progenitor Cells via ERK Activation
Sheng, Weiwei, Malagola, Ermanno, Nienhüser, Henrik, Zhang, Zhengyu, Kim, Woosook, Zamechek, Leah, Sepulveda, Antonia, Hata, Masahiro, Hayakawa, Yoku, Zhao, Chun-Mei, Chen, Duan, Wang, Timothy C.
Published in Cellular and molecular gastroenterology and hepatology (01.01.2020)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2020)
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Journal Article
CXCR4-expressing Mist1 + progenitors in the gastric antrum contribute to gastric cancer development
Sakitani, Kosuke, Hayakawa, Yoku, Deng, Huan, Ariyama, Hiroshi, Kinoshita, Hiroto, Konishi, Mitsuru, Ono, Satoshi, Suzuki, Nobumi, Ihara, Sozaburo, Niu, Zhengchuan, Kim, Woosook, Tanaka, Takayuki, Liu, Haibo, Chen, Xiaowei, Tailor, Yagnesh, Fox, James G, Konieczny, Stephen F, Onodera, Hiroshi, Sepulveda, Antonia R, Asfaha, Samuel, Hirata, Yoshihiro, Worthley, Daniel L, Koike, Kazuhiko, Wang, Timothy C
Published in Oncotarget (19.12.2017)
Published in Oncotarget (19.12.2017)
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Journal Article
Abstract 6640: Stabilized recombinant trefoil factor 2 (TFF2-CTP) enhances anti-tumor activity of PD-1 blockade in mouse models of colorectal cancer
Kim, Woosook, Fu, Na, Duddempudi, Phaneendra, Dubeykovskaya, Zinaida, Almo, Steven, Guha, Chandan, Lederman, Seth, Wang, Timothy
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Isthmus progenitor cells contribute to homeostatic cellular turnover and support regeneration following intestinal injury
Malagola, Ermanno, Vasciaveo, Alessandro, Ochiai, Yosuke, Kim, Woosook, Zheng, Biyun, Zanella, Luca, Wang, Alexander L.E., Middelhoff, Moritz, Nienhüser, Henrik, Deng, Lu, Wu, Feijing, Waterbury, Quin T., Belin, Bryana, LaBella, Jonathan, Zamechek, Leah B., Wong, Melissa H., Li, Linheng, Guha, Chandan, Cheng, Chia-Wei, Yan, Kelley S., Califano, Andrea, Wang, Timothy C.
Published in Cell (06.06.2024)
Published in Cell (06.06.2024)
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Journal Article
Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis
Jiang, Zhengyu, Wu, Feijing, Laise, Pasquale, Takayuki, Tanaka, Na, Fu, Kim, Woosook, Kobayashi, Hiroki, Chang, Wenju, Takahashi, Ryota, Valenti, Giovanni, Sunagawa, Masaki, White, Ruth A, Macchini, Marina, Renz, Bernhard W, Middelhoff, Moritz, Hayakawa, Yoku, Dubeykovskaya, Zinaida A, Tan, Xiangtian, Chu, Timothy H, Nagar, Karan, Tailor, Yagnesh, Belin, Bryana R, Anand, Akanksha, Asfaha, Samuel, Finlayson, Michael O, Iuga, Alina C, Califano, Andrea, Wang, Timothy C
Published in Cell stem cell (03.08.2023)
Published in Cell stem cell (03.08.2023)
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Journal Article
Microbial-Dependent Recruitment of Immature Myeloid Cells Promotes Intestinal Regeneration
Jiang, Zhengyu, Waterbury, Quin T., Malagola, Ermanno, Fu, Na, Kim, Woosook, Ochiai, Yosuke, Wu, Feijing, Guha, Chandan, Shawber, Carrie J., Yan, Kelley S., Wang, Timothy C.
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
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Journal Article
Microbial-Dependent Recruitment of Immature Myeloid Cells Promotes Intestinal RegenerationSummary
Zhengyu Jiang, Quin T. Waterbury, Ermanno Malagola, Na Fu, Woosook Kim, Yosuke Ochiai, Feijing Wu, Chandan Guha, Carrie J. Shawber, Kelley S. Yan, Timothy C. Wang
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
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Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
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