Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche
Ye, Haobin, Adane, Biniam, Khan, Nabilah, Sullivan, Timothy, Minhajuddin, Mohammad, Gasparetto, Maura, Stevens, Brett, Pei, Shanshan, Balys, Marlene, Ashton, John M., Klemm, Dwight J., Woolthuis, Carolien M., Stranahan, Alec W., Park, Christopher Y., Jordan, Craig T.
Published in Cell stem cell (07.07.2016)
Published in Cell stem cell (07.07.2016)
Get full text
Journal Article
Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones
de Boer, Bauke, Prick, Janine, Pruis, Maurien G., Keane, Peter, Imperato, Maria Rosaria, Jaques, Jennifer, Brouwers-Vos, Annet Z., Hogeling, Shanna M., Woolthuis, Carolien M., Nijk, Marije T., Diepstra, Arjan, Wandinger, Sebastian, Versele, Matthias, Attar, Ricardo M., Cockerill, Peter N., Huls, Gerwin, Vellenga, Edo, Mulder, André B., Bonifer, Constanze, Schuringa, Jan Jacob
Published in Cancer cell (08.10.2018)
Published in Cancer cell (08.10.2018)
Get full text
Journal Article
Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
Spevak, Christina C., Elias, Harold K., Kannan, Lavanya, Ali, Mohamed A.E., Martin, Gaëlle H., Selvaraj, Shanmugapriya, Eng, William S., Ernlund, Amanda, Rajasekhar, Vinagolu K., Woolthuis, Carolien M., Zhao, Guangjie, Ha, Caryn J., Schneider, Robert J., Park, Christopher Y.
Published in Cell stem cell (07.05.2020)
Published in Cell stem cell (07.05.2020)
Get full text
Journal Article
CD97 is a critical regulator of acute myeloid leukemia stem cell function
Martin, Gaëlle H, Roy, Nainita, Chakraborty, Sohini, Desrichard, Alexis, Chung, Stephen S, Woolthuis, Carolien M, Hu, Wenhuo, Berezniuk, Iryna, Garrett-Bakelman, Francine E, Hamann, Jörg, Devlin, Sean M, Chan, Timothy A, Park, Christopher Y
Published in The Journal of experimental medicine (07.10.2019)
Published in The Journal of experimental medicine (07.10.2019)
Get full text
Journal Article
miR-99 regulates normal and malignant hematopoietic stem cell self-renewal
Khalaj, Mona, Woolthuis, Carolien M, Hu, Wenhuo, Durham, Benjamin H, Chu, S Haihua, Qamar, Sarah, Armstrong, Scott A, Park, Christopher Y
Published in The Journal of experimental medicine (07.08.2017)
Published in The Journal of experimental medicine (07.08.2017)
Get full text
Journal Article
Aging of hematopoietic stem cells: Intrinsic changes or micro-environmental effects?
Woolthuis, Carolien M, de Haan, Gerald, Huls, Gerwin
Published in Current opinion in immunology (01.08.2011)
Published in Current opinion in immunology (01.08.2011)
Get full text
Journal Article
CombiFlow: combinatorial AML-specific plasma membrane expression profiles allow longitudinal tracking of clones
Houtsma, Roos, van der Meer, Nisha K., Meijer, Kees, Morsink, Linde M., Hogeling, Shanna M., Woolthuis, Carolien M., Ammatuna, Emanuele, Nijk, Marije T., de Boer, Bauke, Huls, Gerwin, Mulder, André B., Schuringa, Jan Jacob
Published in Blood advances (12.04.2022)
Published in Blood advances (12.04.2022)
Get full text
Journal Article
Loss of quiescence and impaired function of CD34(+)/CD38(low) cells one year following autologous stem cell transplantation
Woolthuis, Carolien M, Brouwers-Vos, Annet Z, Huls, Gerwin, de Wolf, Joost Th M, Schuringa, Jan Jacob, Vellenga, Edo
Published in Haematologica (Roma) (01.12.2013)
Published in Haematologica (Roma) (01.12.2013)
Get full text
Journal Article
A single center analysis of nucleophosmin in acute myeloid leukemia: value of combining immunohistochemistry with molecular mutation analysis
Woolthuis, Carolien M, Mulder, André B, Verkaik-Schakel, Rikst Nynke, Rosati, Stefano, Diepstra, Arjan, van den Berg, Eva, Schuringa, Jan Jacob, Vellenga, Edo, Kluin, Philip M, Huls, Gerwin
Published in Haematologica (Roma) (01.10.2013)
Published in Haematologica (Roma) (01.10.2013)
Get full text
Journal Article
Paradoxical down-regulation of p16 mRNA with advancing age in acute myeloid leukemia
de Jonge, Hendrik J M, Woolthuis, Carolien M, de Bont, Eveline S J M, Huls, Gerwin
Published in Aging (Albany, NY.) (23.10.2009)
Published in Aging (Albany, NY.) (23.10.2009)
Get full text
Journal Article
AML at older age: age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance
de Jonge, Hendrik J.M., de Bont, Eveline S.J.M., Valk, Peter J.M., Schuringa, Jan Jacob, Kies, Marcel, Woolthuis, Carolien M., Delwel, Ruud, Veeger, Nic J.G.M., Vellenga, Edo, Löwenberg, Bob, Huls, Gerwin
Published in Blood (01.10.2009)
Published in Blood (01.10.2009)
Get full text
Journal Article
Loss of quiescence and impaired function of CD34+/CD38low cells one year following autologous stem cell transplantation
Woolthuis, Carolien M., Brouwers-Vos, Annet Z., Huls, Gerwin, de Wolf, Joost Th. M., Schuringa, Jan Jacob, Vellenga, Edo
Published in Haematologica (Roma) (01.12.2013)
Published in Haematologica (Roma) (01.12.2013)
Get full text
Journal Article
Aging Impairs Long-Term Hematopoietic Regeneration after Autologous Stem Cell Transplantation
Woolthuis, Carolien M, Mariani, Niccoló, Verkaik-Schakel, Rikst Nynke, Brouwers-Vos, Annet Z, Schuringa, Jan Jacob, Vellenga, Edo, de Wolf, Joost T.M, Huls, Gerwin
Published in Biology of blood and marrow transplantation (01.06.2014)
Published in Biology of blood and marrow transplantation (01.06.2014)
Get full text
Journal Article
Dietary methionine starvation impairs acute myeloid leukemia progression
Cunningham, Alan, Erdem, Ayşegül, Alshamleh, Islam, Geugien, Marjan, Pruis, Maurien, Pereira-Martins, Diego Antonio, van den Heuvel, Fiona A. J., Wierenga, Albertus T. J., ten Berge, Hilde, Dennebos, Robin, van den Boom, Vincent, Hogeling, Shanna M., Weinhäuser, Isabel, Knops, Ruth, de Blaauw, Pim, Heiner-Fokkema, M. Rebecca, Woolthuis, Carolien, Günther, Ulrich L., Rego, Eduardo M., Martens, Joost H. A., Jansen, Joop H., Schwalbe, Harald, Huls, Gerwin, Schuringa, Jan Jacob
Published in Blood (10.11.2022)
Published in Blood (10.11.2022)
Get full text
Journal Article
Mir-99 Regulates Normal and Leukemic Stem Cell Function
Khalaj, Mona, Woolthuis, Carolien, Hu, Wenhuo, Durham, Benjamin Heath, Park, Christopher Y.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
Mtor-Independent Translation in Early Hematopoietic Development
Spevak, Christina, Elias, Harold, Kannan, Lavanya, Martin, Gaelle, Selvaraj, Shanmugapriya, Eng, William, Ernlund, Amanda, Rajasekhar, Vinagolu, Woolthuis, Carolien, Schneider, Robert, Park, Christopher Y.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
Get full text
Journal Article
Abstract PR06: Developmentally regulated mTOR degradation in normal and malignant hematopoiesis
Spevak, Christina C., Elias, Harold K., Kannan, Lavanya, Martin, Gaelle, Selvaraj, Shanmugapriya, Eng, William S., Ernlund, Amanda, Rajasekhar, Vinagolu K., Woolthuis, Carolien M., Schneider, Robert J., Park, Christopher Y.
Published in Molecular cancer research (01.10.2020)
Published in Molecular cancer research (01.10.2020)
Get full text
Journal Article
Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells
Elias, Harold K., Spevak, Christina, Kannan, Lavanya, Ali, Mohamed A.E., Martin, Gaelle H, Selvaraj, Shanmugapriya, Eng, William S, Zhao, Guangjie, Ernlund, Amanda, Rajasekhar, Vinagolu, Woolthuis, Carolien M, Schneider, Robert J, Park, Christopher Y.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
Get full text
Journal Article