Post-translational modifications of Hsp90 and translating the chaperone code
Backe, Sarah J., Sager, Rebecca A., Woodford, Mark R., Makedon, Alan M., Mollapour, Mehdi
Published in The Journal of biological chemistry (07.08.2020)
Published in The Journal of biological chemistry (07.08.2020)
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Journal Article
Epichaperomics reveals dysfunctional chaperone protein networks
Woodford, Mark R., Bourboulia, Dimitra, Mollapour, Mehdi
Published in Nature communications (22.08.2023)
Published in Nature communications (22.08.2023)
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Journal Article
Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis
Baker-Williams, Alexander J., Hashmi, Fiza, Budzyński, Marek A., Woodford, Mark R., Gleicher, Stephanie, Himanen, Samu V., Makedon, Alan M., Friedman, Derek, Cortes, Stephanie, Namek, Sara, Stetler-Stevenson, William G., Bratslavsky, Gennady, Bah, Alaji, Mollapour, Mehdi, Sistonen, Lea, Bourboulia, Dimitra
Published in Cell reports (Cambridge) (13.08.2019)
Published in Cell reports (Cambridge) (13.08.2019)
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Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors
Woodford, Mark R., Truman, Andrew W., Dunn, Diana M., Jensen, Sandra M., Cotran, Richard, Bullard, Renee, Abouelleil, Mourad, Beebe, Kristin, Wolfgeher, Donald, Wierzbicki, Sara, Post, Dawn E., Caza, Tiffany, Tsutsumi, Shinji, Panaretou, Barry, Kron, Stephen J., Trepel, Jane B., Landas, Steve, Prodromou, Chrisostomos, Shapiro, Oleg, Stetler-Stevenson, William G., Bourboulia, Dimitra, Neckers, Len, Bratslavsky, Gennady, Mollapour, Mehdi
Published in Cell reports (Cambridge) (02.02.2016)
Published in Cell reports (Cambridge) (02.02.2016)
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Journal Article
The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect
Woodford, Mark R., Baker-Williams, Alexander J., Sager, Rebecca A., Backe, Sarah J., Blanden, Adam R., Hashmi, Fiza, Kancherla, Priyanka, Gori, Alessandro, Loiselle, David R., Castelli, Matteo, Serapian, Stefano A., Colombo, Giorgio, Haystead, Timothy A., Jensen, Sandra M., Stetler-Stevenson, William G., Loh, Stewart N., Schmidt, Laura S., Linehan, W. Marston, Bah, Alaji, Bourboulia, Dimitra, Bratslavsky, Gennady, Mollapour, Mehdi
Published in Nature structural & molecular biology (01.08.2021)
Published in Nature structural & molecular biology (01.08.2021)
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Journal Article
PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling
Backe, Sarah J., Votra, SarahBeth D., Stokes, Matthew P., Sebestyén, Endre, Castelli, Matteo, Torielli, Luca, Colombo, Giorgio, Woodford, Mark R., Mollapour, Mehdi, Bourboulia, Dimitra
Published in Cell reports (Cambridge) (27.06.2023)
Published in Cell reports (Cambridge) (27.06.2023)
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Journal Article
TRAP1 Chaperones the Metabolic Switch in Cancer
Wengert, Laura A., Backe, Sarah J., Bourboulia, Dimitra, Mollapour, Mehdi, Woodford, Mark R.
Published in Biomolecules (Basel, Switzerland) (04.06.2022)
Published in Biomolecules (Basel, Switzerland) (04.06.2022)
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Journal Article
Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
Backe, Sarah J., Sager, Rebecca A., Heritz, Jennifer A., Wengert, Laura A., Meluni, Katherine A., Aran-Guiu, Xavier, Panaretou, Barry, Woodford, Mark R., Prodromou, Chrisostomos, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (25.07.2023)
Published in Cell reports (Cambridge) (25.07.2023)
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Journal Article
Asymmetric Hsp90 N Domain SUMOylation Recruits Aha1 and ATP-Competitive Inhibitors
Mollapour, Mehdi, Bourboulia, Dimitra, Beebe, Kristin, Woodford, Mark R., Polier, Sigrun, Hoang, Anthony, Chelluri, Raju, Li, Yu, Guo, Ailan, Lee, Min-Jung, Fotooh-Abadi, Elham, Khan, Sahar, Prince, Thomas, Miyajima, Naoto, Yoshida, Soichiro, Tsutsumi, Shinji, Xu, Wanping, Panaretou, Barry, Stetler-Stevenson, William G., Bratslavsky, Gennady, Trepel, Jane B., Prodromou, Chrisostomos, Neckers, Len
Published in Molecular cell (23.01.2014)
Published in Molecular cell (23.01.2014)
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The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
Woodford, Mark R., Dunn, Diana M., Blanden, Adam R., Capriotti, Dante, Loiselle, David, Prodromou, Chrisostomos, Panaretou, Barry, Hughes, Philip F., Smith, Aaron, Ackerman, Wendi, Haystead, Timothy A., Loh, Stewart N., Bourboulia, Dimitra, Schmidt, Laura S., Marston Linehan, W., Bratslavsky, Gennady, Mollapour, Mehdi
Published in Nature communications (29.06.2016)
Published in Nature communications (29.06.2016)
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Journal Article
Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90
Sager, Rebecca A., Woodford, Mark R., Backe, Sarah J., Makedon, Alan M., Baker-Williams, Alexander J., DiGregorio, Bryanna T., Loiselle, David R., Haystead, Timothy A., Zachara, Natasha E., Prodromou, Chrisostomos, Bourboulia, Dimitra, Schmidt, Laura S., Linehan, W. Marston, Bratslavsky, Gennady, Mollapour, Mehdi
Published in Cell reports (Cambridge) (29.01.2019)
Published in Cell reports (Cambridge) (29.01.2019)
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Journal Article
Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
Backe, Sarah J., Sager, Rebecca A., Heritz, Jennifer A., Wengert, Laura A., Meluni, Katherine A., Aran-Guiu, Xavier, Panaretou, Barry, Woodford, Mark R., Prodromou, Chrisostomos, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (23.01.2024)
Published in Cell reports (Cambridge) (23.01.2024)
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Journal Article
Targeting Hsp90 in Non-Cancerous Maladies
Woodford, Mark R, Dunn, Diana M, Ciciarelli, Joseph G, Beebe, Kristin, Neckers, Len, Mollapour, Mehdi
Published in Current topics in medicinal chemistry (01.10.2016)
Published in Current topics in medicinal chemistry (01.10.2016)
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Journal Article
c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells
Dunn, Diana M., Woodford, Mark R., Truman, Andrew W., Jensen, Sandra M., Schulman, Jacqualyn, Caza, Tiffany, Remillard, Taylor C., Loiselle, David, Wolfgeher, Donald, Blagg, Brian S.J., Franco, Lucas, Haystead, Timothy A., Daturpalli, Soumya, Mayer, Matthias P., Trepel, Jane B., Morgan, Rhodri M.L., Prodromou, Chrisostomos, Kron, Stephen J., Panaretou, Barry, Stetler-Stevenson, William G., Landas, Steve K., Neckers, Len, Bratslavsky, Gennady, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (11.08.2015)
Published in Cell reports (Cambridge) (11.08.2015)
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Journal Article
Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer
Dushukyan, Natela, Dunn, Diana M., Sager, Rebecca A., Woodford, Mark R., Loiselle, David R., Daneshvar, Michael, Baker-Williams, Alexander J., Chisholm, John D., Truman, Andrew W., Vaughan, Cara K., Haystead, Timothy A., Bratslavsky, Gennady, Bourboulia, Dimitra, Mollapour, Mehdi
Published in Cell reports (Cambridge) (14.11.2017)
Published in Cell reports (Cambridge) (14.11.2017)
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Journal Article
Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90–Client Interactions
Paladino, Antonella, Woodford, Mark R., Backe, Sarah J., Sager, Rebecca A., Kancherla, Priyanka, Daneshvar, Michael A., Chen, Victor Z., Bourboulia, Dimitra, Ahanin, Elham F., Prodromou, Chrisostomos, Bergamaschi, Greta, Strada, Alessandro, Cretich, Marina, Gori, Alessandro, Veronesi, Marina, Bandiera, Tiziano, Vanna, Renzo, Bratslavsky, Gennady, Serapian, Stefano A., Mollapour, Mehdi, Colombo, Giorgio
Published in Chemistry : a European journal (03.08.2020)
Published in Chemistry : a European journal (03.08.2020)
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Journal Article
Targeting extracellular Hsp90: A unique frontier against cancer
Sager, Rebecca A., Khan, Farzana, Toneatto, Lorenzo, Votra, SarahBeth D., Backe, Sarah J., Woodford, Mark R., Mollapour, Mehdi, Bourboulia, Dimitra
Published in Frontiers in molecular biosciences (17.08.2022)
Published in Frontiers in molecular biosciences (17.08.2022)
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Valproic Acid Alters Angiogenic and Trophic Gene Expression in Human Prostate Cancer Models
Chelluri, Raju, Caza, Tiffany, Woodford, Mark R, Reeder, Jay E, Bratslavsky, Gennady, Byler, Timothy
Published in Anticancer research (01.10.2016)
Published in Anticancer research (01.10.2016)
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