Advances in oligonucleotide drug delivery
Roberts, Thomas C., Langer, Robert, Wood, Matthew J. A.
Published in Nature reviews. Drug discovery (01.10.2020)
Published in Nature reviews. Drug discovery (01.10.2020)
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Journal Article
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Wood, Matthew J A, Alvarez-Erviti, Lydia, Seow, Yiqi, Yin, HaiFang, Betts, Corinne, Lakhal, Samira
Published in Nature biotechnology (01.04.2011)
Published in Nature biotechnology (01.04.2011)
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Journal Article
DNA Cage Delivery to Mammalian Cells
Walsh, Anthony S, Yin, HaiFang, Erben, Christoph M, Wood, Matthew J. A, Turberfield, Andrew J
Published in ACS nano (26.07.2011)
Published in ACS nano (26.07.2011)
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Journal Article
Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study
Cirak, Sebahattin, MD, Arechavala-Gomeza, Virginia, PhD, Guglieri, Michela, MD, Feng, Lucy, PhD, Torelli, Silvia, PhD, Anthony, Karen, PhD, Abbs, Stephen, PhD, Garralda, Maria Elena, Prof, Bourke, John, MD, Wells, Dominic J, Prof, Dickson, George, Prof, Wood, Matthew JA, MD PhD, Wilton, Steve D, Prof, Straub, Volker, Prof, Kole, Ryszard, Prof, Shrewsbury, Stephen B, MD, Sewry, Caroline, Prof, Morgan, Jennifer E, PhD, Bushby, Kate, Prof, Muntoni, Francesco, Prof
Published in The Lancet (British edition) (13.08.2011)
Published in The Lancet (British edition) (13.08.2011)
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Journal Article
Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons
Heman-Ackah, Sabrina M, Manzano, Raquel, Hoozemans, Jeroen J M, Scheper, Wiep, Flynn, Rowan, Haerty, Wilfried, Cowley, Sally A, Bassett, Andrew R, Wood, Matthew J A
Published in Human molecular genetics (15.11.2017)
Published in Human molecular genetics (15.11.2017)
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Journal Article
A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA
de Jong, Olivier G., Murphy, Daniel E., Mäger, Imre, Willms, Eduard, Garcia-Guerra, Antonio, Gitz-Francois, Jerney J., Lefferts, Juliet, Gupta, Dhanu, Steenbeek, Sander C., van Rheenen, Jacco, El Andaloussi, Samir, Schiffelers, Raymond M., Wood, Matthew J. A., Vader, Pieter
Published in Nature communications (28.02.2020)
Published in Nature communications (28.02.2020)
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Journal Article
GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain
Dar, Ghulam Hassan, Mendes, Cláudia C., Kuan, Wei-Li, Speciale, Alfina A., Conceição, Mariana, Görgens, André, Uliyakina, Inna, Lobo, Miguel J., Lim, Wooi F., EL Andaloussi, Samir, Mäger, Imre, Roberts, Thomas C., Barker, Roger A., Goberdhan, Deborah C. I., Wilson, Clive, Wood, Matthew J. A.
Published in Nature communications (18.11.2021)
Published in Nature communications (18.11.2021)
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Journal Article
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
Wiklander, Oscar P. B., Nordin, Joel Z., O'Loughlin, Aisling, Gustafsson, Ylva, Corso, Giulia, Mäger, Imre, Vader, Pieter, Lee, Yi, Sork, Helena, Seow, Yiqi, Heldring, Nina, Alvarez-Erviti, Lydia, Smith, CI Edvard, Le Blanc, Katarina, Macchiarini, Paolo, Jungebluth, Philipp, Wood, Matthew J. A., Andaloussi, Samir EL
Published in Journal of extracellular vesicles (01.01.2015)
Published in Journal of extracellular vesicles (01.01.2015)
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Journal Article
An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides
Baker, Ysobel R., Thorpe, Cameron, Chen, Jinfeng, Poller, Laura M., Cox, Lina, Kumar, Pawan, Lim, Wooi F., Lie, Lillian, McClorey, Graham, Epple, Sven, Singleton, Daniel, McDonough, Michael A., Hardwick, Jack S., Christensen, Kirsten E., Wood, Matthew J. A., Hall, James P., El-Sagheer, Afaf H., Brown, Tom
Published in Nature communications (12.07.2022)
Published in Nature communications (12.07.2022)
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Journal Article
A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice
Yin, HaiFang, Moulton, Hong M., Betts, Corinne, Seow, Yiqi, Boutilier, Jordan, Iverson, Patrick L., Wood, Matthew J.A.
Published in Human molecular genetics (15.11.2009)
Published in Human molecular genetics (15.11.2009)
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Journal Article
FKRP-dependent glycosylation of fibronectin regulates muscle pathology in muscular dystrophy
Wood, A. J., Lin, C. H., Li, M., Nishtala, K., Alaei, S., Rossello, F., Sonntag, C., Hersey, L., Miles, L. B., Krisp, C., Dudczig, S., Fulcher, A. J., Gibertini, S., Conroy, P. J., Siegel, A., Mora, M., Jusuf, P., Packer, N. H., Currie, P. D.
Published in Nature communications (19.05.2021)
Published in Nature communications (19.05.2021)
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Journal Article
Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function
Yin, HaiFang, Moulton, Hong M., Seow, Yiqi, Boyd, Corinne, Boutilier, Jordan, Iverson, Patrick, Wood, Matthew J.A.
Published in Human Molecular Genetics (15.12.2008)
Published in Human Molecular Genetics (15.12.2008)
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Web Resource
Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy
LEE, Yi, ANDALOUSSI, Samir El, WOOD, Matthew J. A
Published in Human molecular genetics (15.10.2012)
Published in Human molecular genetics (15.10.2012)
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Journal Article
Molecular and electrophysiological features of spinocerebellar ataxia type seven in induced pluripotent stem cells
Burman, Richard J, Watson, Lauren M, Smith, Danielle C, Raimondo, Joseph V, Ballo, Robea, Scholefield, Janine, Cowley, Sally A, Wood, Matthew J A, Kidson, Susan H, Greenberg, Leslie J
Published in PloS one (24.02.2021)
Published in PloS one (24.02.2021)
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Journal Article
RNA-targeted splice-correction therapy for neuromuscular disease
Wood, Matthew J. A., Gait, Michael J., Yin, Haifang
Published in Brain (London, England : 1878) (01.04.2010)
Published in Brain (London, England : 1878) (01.04.2010)
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