Highly Potent First Examples of Dual Aromatase−Steroid Sulfatase Inhibitors based on a Biphenyl Template
Woo, L. W. Lawrence, Jackson, Toby, Putey, Aurélien, Cozier, Gyles, Leonard, Philip, Acharya, K. Ravi, Chander, Surinder K, Purohit, Atul, Reed, Michael J, Potter, Barry V. L
Published in Journal of medicinal chemistry (11.03.2010)
Published in Journal of medicinal chemistry (11.03.2010)
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Journal Article
Aromatase and Dual Aromatase-Steroid Sulfatase Inhibitors from the Letrozole and Vorozole Templates
Wood, Paul M., Woo, L. W. Lawrence, Thomas, Mark P., Mahon, Mary F., Purohit, Atul, Potter, Barry V. L.
Published in ChemMedChem (01.08.2011)
Published in ChemMedChem (01.08.2011)
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Journal Article
Structure-Activity Relationship for the First-in-Class Clinical Steroid Sulfatase Inhibitor Irosustat (STX64, BN83495)
Woo, L. W. Lawrence, Ganeshapillai, Dharshini, Thomas, Mark P., Sutcliffe, Oliver B., Malini, Bindu, Mahon, Mary F., Purohit, Atul, Potter, Barry V. L.
Published in ChemMedChem (04.11.2011)
Published in ChemMedChem (04.11.2011)
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Journal Article
C‑3- and C‑4-Substituted Bicyclic Coumarin Sulfamates as Potent Steroid Sulfatase Inhibitors
Ganeshapillai, Dharshini, Woo, L. W. Lawrence, Thomas, Mark P, Purohit, Atul, Potter, Barry V. L
Published in ACS omega (30.09.2018)
Published in ACS omega (30.09.2018)
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The Development of Steroid Sulfatase Inhibitors for Hormone-Dependent Cancer Therapy
Day, Joanna M., Purohit, Atul, Tutill, Helena J., Foster, Paul A., Woo, L. W. Lawrence, Potter, Barry V. L., Reed, Michael J.
Published in Annals of the New York Academy of Sciences (01.02.2009)
Published in Annals of the New York Academy of Sciences (01.02.2009)
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In vivo Efficacy of STX213, A Second-Generation Steroid Sulfatase Inhibitor, for Hormone-Dependent Breast Cancer Therapy
FOSTER, Paul A, NEWMAN, Simon P, CHANDER, Surinder K, STENGEL, Chloe, JHALLI, Roma, WOO, Lawrence L. W, POTTER, Barry V. L, REED, Michael J, PUROHIT, Atul
Published in Clinical cancer research (15.09.2006)
Published in Clinical cancer research (15.09.2006)
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Efficacy of three potent steroid sulfatase inhibitors: pre-clinical investigations for their use in the treatment of hormone-dependent breast cancer
Foster, Paul A., Chander, Surinder K., Parsons, Michael F. C., Newman, Simon P., Woo, L. W. Lawrence, Potter, Barry V. L., Reed, Michael J., Purohit, Atul
Published in Breast cancer research and treatment (01.09.2008)
Published in Breast cancer research and treatment (01.09.2008)
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Bicyclic Derivatives of the Potent Dual Aromatase-Steroid Sulfatase Inhibitor 2-Bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenylsulfamate: Synthesis, SAR, Crystal Structure, and in vitro and in vivo Activities
Wood, Paul M., Woo, L. W. Lawrence, Labrosse, Jean-Robert, Thomas, Mark P., Mahon, Mary F., Chander, Surinder K., Purohit, Atul, Reed, Michael J., Potter, Barry V. L.
Published in ChemMedChem (03.09.2010)
Published in ChemMedChem (03.09.2010)
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Determination of the absolute configuration of aromatase and dual aromatase-sulfatase inhibitors by vibrational and electronic circular dichroism spectra analysis
Abbate, Sergio, Longhi, Giovanna, Castiglioni, Ettore, Lebon, France, Wood, Paul M., Woo, Lawrence W. L., Potter, Barry V. L.
Published in Chirality (New York, N.Y.) (01.10.2009)
Published in Chirality (New York, N.Y.) (01.10.2009)
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Synthesis of Aromatase Inhibitors and Dual Aromatase Steroid Sulfatase Inhibitors by Linking an Arylsulfamate Motif to 4-(4H-1,2,4-triazol-4-ylamino)benzonitrile: SAR, Crystal Structures, in vitro and in vivo Activities
Bubert, Christian, Woo, L. W. Lawrence, Sutcliffe, Oliver B., Mahon, Mary F., Chander, Surinder K., Purohit, Atul, Reed, Michael J., Potter, Barry V. L.
Published in ChemMedChem (17.11.2008)
Published in ChemMedChem (17.11.2008)
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Journal Article
Development of steroid sulfatase inhibitors
Woo, L.W. Lawrence, Purohit, Atul, Potter, Barry V.L.
Published in Molecular and cellular endocrinology (04.07.2011)
Published in Molecular and cellular endocrinology (04.07.2011)
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Journal Article
Steroid sulfatase: A pivotal player in estrogen synthesis and metabolism
Purohit, Atul, Woo, L.W. Lawrence, Potter, Barry V.L.
Published in Molecular and cellular endocrinology (04.07.2011)
Published in Molecular and cellular endocrinology (04.07.2011)
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Journal Article
Phase I Study of STX 64 (667 Coumate) in Breast Cancer Patients: The First Study of a Steroid Sulfatase Inhibitor
STANWAY, Susannah J, PUROHIT, Atul, ELLIOTT, Moira, POTTER, Barry V. L, REED, Michael J, COOMBES, R. Charles, WOO, L. W. Lawrence, SUFI, Saulat, VIGUSHIN, David, WARD, Rebecca, WILSON, Richard H, STANCZYK, Frank Z, DOBBS, Nicola, KULINSKAYA, Elena
Published in Clinical cancer research (01.03.2006)
Published in Clinical cancer research (01.03.2006)
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Journal Article
Chiral Aromatase and Dual Aromatase−Steroid Sulfatase Inhibitors from the Letrozole Template: Synthesis, Absolute Configuration, and In Vitro Activity
Wood, Paul M, Woo, L. W. Lawrence, Labrosse, Jean-Robert, Trusselle, Melanie N, Abbate, Sergio, Longhi, Giovanna, Castiglioni, Ettore, Lebon, France, Purohit, Atul, Reed, Michael J, Potter, Barry V. L
Published in Journal of medicinal chemistry (24.07.2008)
Published in Journal of medicinal chemistry (24.07.2008)
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Journal Article
Dual Aromatase−Steroid Sulfatase Inhibitors
Woo, L. W. Lawrence, Bubert, Christian, Sutcliffe, Oliver B, Smith, Andrew, Chander, Surinder K, Mahon, Mary F, Purohit, Atul, Reed, Michael J, Potter, Barry V. L
Published in Journal of medicinal chemistry (26.07.2007)
Published in Journal of medicinal chemistry (26.07.2007)
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Journal Article
Synthesis and Structure-Activity Relationship Studies of Derivatives of the Dual Aromatase-Sulfatase Inhibitor 4-{[(4-Cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate
Woo, L. W. Lawrence, Wood, Paul M., Bubert, Christian, Thomas, Mark P., Purohit, Atul, Potter, Barry V. L.
Published in ChemMedChem (01.05.2013)
Published in ChemMedChem (01.05.2013)
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