Biased β2‐adrenoceptor signalling in heart failure: pathophysiology and drug discovery
Woo, Anthony Yiu‐Ho, Song, Ying, Xiao, Rui‐Ping, Zhu, Weizhong
Published in British journal of pharmacology (01.12.2015)
Published in British journal of pharmacology (01.12.2015)
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Journal Article
GRK2/β‐arrestin mediates arginine vasopressin‐induced cardiac fibroblast proliferation
Chen, Yunxuan, Xu, Feifei, Zhang, Lingling, Wang, Xiaojun, Wang, Yifan, Woo, Anthony Yiu‐Ho, Zhu, Weizhong
Published in Clinical and experimental pharmacology & physiology (01.02.2017)
Published in Clinical and experimental pharmacology & physiology (01.02.2017)
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Journal Article
Comparative molecular field analysis of fenoterol derivatives: A platform towards highly selective and effective β2-adrenergic receptor agonists
JOZWIAK, Krzysztof, YIU-HO WOO, Anthony, TANGA, Mary J, TOLL, Lawrence, JIMENEZ, Lucita, KOZOCAS, Joseph A, PLAZINSKA, Anita, XIAO, Rui-Ping, WAINER, Irving W
Published in Bioorganic & medicinal chemistry (01.01.2010)
Published in Bioorganic & medicinal chemistry (01.01.2010)
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Journal Article
Tyrosine 308 Is Necessary for Ligand-directed Gs Protein-biased Signaling of β2-Adrenoceptor
Woo, Anthony Yiu-Ho, Jozwiak, Krzysztof, Toll, Lawrence, Tanga, Mary J., Kozocas, Joseph A., Jimenez, Lucita, Huang, Ying, Song, Ying, Plazinska, Anita, Pajak, Karolina, Paul, Rajib K., Bernier, Michel, Wainer, Irving W., Xiao, Rui-Ping
Published in The Journal of biological chemistry (11.07.2014)
Published in The Journal of biological chemistry (11.07.2014)
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Journal Article
Discovery of β-arrestin-biased β2-adrenoceptor agonists from 2-amino-2-phenylethanol derivatives
Woo, Anthony Yiu-Ho, Ge, Xin-yue, Pan, Li, Xing, Gang, Mo, Yong-mei, Xing, Rui-juan, Li, Xiao-ran, Zhang, Yu-yang, Wainer, Irving W., Cheng, Mao-sheng, Xiao, Rui-ping
Published in Acta pharmacologica Sinica (01.08.2019)
Published in Acta pharmacologica Sinica (01.08.2019)
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Journal Article
ADRB2 polymorphism Arg16Gly modifies the natural outcome of heart failure and dictates therapeutic response to β-blockers in patients with heart failure
Huang, Jin, Li, Chenze, Song, Ying, Fan, Xiaohan, You, Ling, Tan, Lun, Xiao, Lei, Li, Qing, Ruan, Guoran, Hu, Senlin, Cui, Wei, Li, Zongzhe, Ni, Li, Chen, Chen, Woo, Anthony Yiu-Ho, Xiao, Rui-Ping, Wang, Dao Wen
Published in Cell discovery (23.10.2018)
Published in Cell discovery (23.10.2018)
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Journal Article
Effect of fenoterol stereochemistry on the β2 adrenergic receptor system: Ligand-directed chiral recognition
Jozwiak, Krzysztof, Plazinska, Anita, Toll, Lawrence, Jimenez, Lucita, Woo, Anthony Yiu-Ho, Xiao, Rui-Ping, Wainer, Irving W.
Published in Chirality (New York, N.Y.) (2011)
Published in Chirality (New York, N.Y.) (2011)
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Journal Article
Recent Advances in β2‑Agonists for Treatment of Chronic Respiratory Diseases and Heart Failure
Xing, Gang, Woo, Anthony Yiu-Ho, Pan, Li, Lin, Bin, Cheng, Mao-Sheng
Published in Journal of medicinal chemistry (24.12.2020)
Published in Journal of medicinal chemistry (24.12.2020)
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Journal Article
8-Hydroxyquinolin-2(1H)-one analogues as potential β2-agonists: Design, synthesis and activity study
Xing, Gang, Zhi, Zhengxing, Yi, Ce, Zou, Jitian, Jing, Xuefeng, Yiu-Ho Woo, Anthony, Lin, Bin, Pan, Li, Zhang, Yuyang, Cheng, Maosheng
Published in European journal of medicinal chemistry (15.11.2021)
Published in European journal of medicinal chemistry (15.11.2021)
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Journal Article
Heterodimerization With 5-HT2BR Is Indispensable for β2AR-Mediated Cardioprotection
Song, Ying, Xu, Chanjuan, Liu, Jianfeng, Li, Yulong, Wang, Huan, Shan, Dan, Wainer, Irving W, Hu, Xinli, Zhang, Yan, Woo, Anthony Yiu-Ho, Xiao, Rui-Ping
Published in Circulation research (22.01.2021)
Published in Circulation research (22.01.2021)
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Journal Article
Design, synthesis and biological evaluation of 8-(2-amino-1-hydroxyethyl)-6-hydroxy-1,4-benzoxazine-3(4H)-one derivatives as potent β2-adrenoceptor agonists
Yi, Ce, Xing, Gang, Wang, Siqi, Li, Xiaoran, Liu, Yichuang, Li, Jinyan, Lin, Bin, Woo, Anthony Yiu-Ho, Zhang, Yuyang, Pan, Li, Cheng, Maosheng
Published in Bioorganic & medicinal chemistry (01.01.2020)
Published in Bioorganic & medicinal chemistry (01.01.2020)
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Journal Article
Discovery of a Highly Selective β2‑Adrenoceptor Agonist with a 2‑Amino-2-phenylethanol Scaffold as an Oral Antiasthmatic Agent
Xing, Gang, Li, Dahong, Woo, Anthony Yiu-Ho, Zhi, Zhengxing, Ji, Lei, Xing, Ruijuan, Lv, Hailiang, He, Bin, An, Hui, Zhao, Haiyan, Lin, Bin, Pan, Li, Cheng, Maosheng
Published in Journal of medicinal chemistry (14.04.2022)
Published in Journal of medicinal chemistry (14.04.2022)
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Journal Article
Biased Agonism at the Angiotensin Receptor: Blocker and Calcium Sensitizer at the Same Time
Woo, Anthony Yiu-Ho, Komuro, Issei, Xiao, Rui-Ping
Published in Circulation (New York, N.Y.) (14.03.2017)
Published in Circulation (New York, N.Y.) (14.03.2017)
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Journal Article
Synthesis and biological evaluation of β2-adrenoceptor agonists bearing the 2-amino-2-phenylethanol scaffold
Ge, Xinyue, Woo, Anthony Yiu-Ho, Xing, Gang, Lu, Yali, Mo, Yongmei, Zhao, Ying, Lan, Yi, Li, Jinyan, Yan, Haining, Pan, Li, Zhang, Yuyang, Lin, Bin, Cheng, Maosheng
Published in European journal of medicinal chemistry (25.05.2018)
Published in European journal of medicinal chemistry (25.05.2018)
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Journal Article
Vasopressin V1A receptor mediates cell proliferation through GRK2-EGFR-ERK1/2 pathway in A7r5 cells
Zhang, Lingling, Wang, Xiaojun, Cao, Hong, Chen, Yunxuan, Chen, Xianfan, Zhao, Xi, Xu, Feifei, Wang, Yifan, Woo, Anthony Yiu-Ho, Zhu, Weizhong
Published in European journal of pharmacology (05.12.2016)
Published in European journal of pharmacology (05.12.2016)
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Journal Article
Stereochemistry of an Agonist Determines Coupling Preference of β 2 -Adrenoceptor to Different G Proteins in Cardiomyocytes
Woo, Anthony Yiu-Ho, Wang, Tian-Bing, Zeng, Xiaokun, Zhu, Weizhong, Abernethy, Darrell R., Wainer, Irving W., Xiao, Rui-Ping
Published in Molecular pharmacology (01.01.2009)
Published in Molecular pharmacology (01.01.2009)
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Journal Article
Synthesis, biological evaluation and molecular modeling of 2-amino-2-phenylethanol derivatives as novel β2-adrenoceptor agonists
Ge, Xinyue, Mo, Yongmei, Xing, Gang, Ji, Lei, Zhao, Haiyan, Chen, Jianfang, He, Bin, Chen, Xuyao, Xing, Ruijuan, Li, Xiaoqiang, Zhao, Ying, Li, Jinyan, Yan, Haining, Woo, Anthony Yiu-Ho, Zhang, Yuyang, Lin, Bin, Pan, Li, Cheng, Maosheng
Published in Bioorganic chemistry (01.09.2018)
Published in Bioorganic chemistry (01.09.2018)
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Journal Article