Two‐metal ion mechanism of RNA cleavage by HIV RNase H and mechanism‐based design of selective HIV RNase H inhibitors
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Published in Nucleic acids research (01.12.2003)
Published in Nucleic acids research (01.12.2003)
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Activity of the isolated HIV RNase H domain and specific inhibition by N-hydroxyimides
Hang, Julie Qi, Rajendran, Surendran, Yang, Yanli, Li, Yu, Wong Kai In, Philippe, Overton, Hilary, Parkes, Kevin E.B., Cammack, Nick, Martin, Joseph A., Klumpp, Klaus
Published in Biochemical and biophysical research communications (30.04.2004)
Published in Biochemical and biophysical research communications (30.04.2004)
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Nucleoside Analogues as Highly Potent and Selective Inhibitors of Herpes Simplex Virus Thymidine Kinase
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Published in Bioorganic & medicinal chemistry letters (09.07.2001)
Published in Bioorganic & medicinal chemistry letters (09.07.2001)
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SAR, Pharmacokinetics, Safety, and Efficacy of Glucokinase Activating 2-(4-Sulfonylphenyl)-N-thiazol-2-ylacetamides: Discovery of PSN-GK1
Bertram, Lisa S, Black, Daniel, Briner, Paul H, Chatfield, Rosemary, Cooke, Andrew, Fyfe, Matthew C. T, Murray, P. John, Naud, Frédéric, Nawano, Masao, Procter, Martin J, Rakipovski, Günaj, Rasamison, Chrystelle M, Reynet, Christine, Schofield, Karen L, Shah, Vilas K, Spindler, Felix, Taylor, Amanda, Turton, Roy, Williams, Geoffrey M, Wong-Kai-In, Philippe, Yasuda, Kosuke
Published in Journal of medicinal chemistry (24.07.2008)
Published in Journal of medicinal chemistry (24.07.2008)
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Design and synthesis of potent carboxylic acid DGAT1 inhibitors with high cell permeability
Bali, Ustav, Barba, Oscar, Dawson, Graham, Gattrell, William T., Horswill, James G., Pan, David A., Procter, Martin J., Rasamison, Chrystelle M., Sambrook Smith, Colin P., Taylor-Warne, Amanda, Wong-Kai-In, Philippe
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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ARYL UREA DERIVATIVE
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Year of Publication 26.07.2012
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Year of Publication 26.07.2012
Patent
ARYL UREA DERIVATIVES FOR TREATING OBESITY
WONG-KAI-IN, PHILIPPE, SWAIN, SIMON ANDREW, FYFE, MATTHEW COLIN THOR, PROCTER, MARTIN JAMES, JEEVARATNAM, REVATHY PERPETUA, BLOXHAM, JASON, SCHOFIELD, KAREN LESLEY, HORSWILL, JAMES, KEILY, JOHN, SHAABAN, SALAM
Year of Publication 23.05.2007
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Year of Publication 23.05.2007
Patent
ARYL UREA DERIVATIVES FOR TREATING OBESITY
FYFE, MATTHEW, COLIN, THOR, JEEVARATNAM, REVATHY, PERPETUA, WONG-KAI-IN, PHILIPPE, PROCTER, MARTIN, JAMES, SWAIN, SIMON, ANDREW, BLOXHAM, JASON, SCHOFIELD, KAREN, LESLEY, HORSWILL, JAMES, KEILY, JOHN, SHAABAN, SALAM
Year of Publication 21.12.2006
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Year of Publication 21.12.2006
Patent