Quantitative genome-wide genetic interaction screens reveal global epistatic relationships of protein complexes in Escherichia coli
Babu, Mohan, Arnold, Roland, Bundalovic-Torma, Cedoljub, Gagarinova, Alla, Wong, Keith S, Kumar, Ashwani, Stewart, Geordie, Samanfar, Bahram, Aoki, Hiroyuki, Wagih, Omar, Vlasblom, James, Phanse, Sadhna, Lad, Krunal, Yeou Hsiung Yu, Angela, Graham, Christopher, Jin, Ke, Brown, Eric, Golshani, Ashkan, Kim, Philip, Moreno-Hagelsieb, Gabriel, Greenblatt, Jack, Houry, Walid A, Parkinson, John, Emili, Andrew
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
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Journal Article
The Role of ClpP Protease in Bacterial Pathogenesis and Human Diseases
Bhandari, Vaibhav, Wong, Keith S, Zhou, Jin Lin, Mabanglo, Mark F, Batey, Robert A, Houry, Walid A
Published in ACS chemical biology (15.06.2018)
Published in ACS chemical biology (15.06.2018)
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Journal Article
Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases
Lin, Funing, Mabanglo, Mark F., Zhou, Jin Lin, Binepal, Gursonika, Barghash, Marim M., Wong, Keith S., Gray-Owen, Scott D., Batey, Robert A., Houry, Walid A.
Published in Journal of medicinal chemistry (12.09.2024)
Published in Journal of medicinal chemistry (12.09.2024)
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Journal Article
Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death
Wong, Keith S., Mabanglo, Mark F., Seraphim, Thiago V., Mollica, Antonio, Mao, Yu-Qian, Rizzolo, Kamran, Leung, Elisa, Moutaoufik, Mohamed T., Hoell, Larissa, Phanse, Sadhna, Goodreid, Jordan, Barbosa, Leandro R.S., Ramos, Carlos H.I., Babu, Mohan, Mennella, Vito, Batey, Robert A., Schimmer, Aaron D., Houry, Walid A.
Published in Cell chemical biology (16.08.2018)
Published in Cell chemical biology (16.08.2018)
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Journal Article
Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome
Mabanglo, Mark F., Wong, Keith S., Barghash, Marim M., Leung, Elisa, Chuang, Stephanie H.W., Ardalan, Afshan, Majaesic, Emily M., Wong, Cassandra J., Zhang, Shen, Lang, Henk, Karanewsky, Donald S., Iwanowicz, Andrew A., Graves, Lee M., Iwanowicz, Edwin J., Gingras, Anne-Claude, Houry, Walid A.
Published in Structure (London) (02.02.2023)
Published in Structure (London) (02.02.2023)
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Journal Article
Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial Activity
Goodreid, Jordan D, Janetzko, John, Santa Maria, John P, Wong, Keith S, Leung, Elisa, Eger, Bryan T, Bryson, Steve, Pai, Emil F, Gray-Owen, Scott D, Walker, Suzanne, Houry, Walid A, Batey, Robert A
Published in Journal of medicinal chemistry (28.01.2016)
Published in Journal of medicinal chemistry (28.01.2016)
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Journal Article
Development of Antibiotics That Dysregulate the Neisserial ClpP Protease
Binepal, Gursonika, Mabanglo, Mark F, Goodreid, Jordan D, Leung, Elisa, Barghash, Marim M, Wong, Keith S, Lin, Funing, Cossette, Michele, Bansagi, Jazmin, Song, Boxi, Balasco Serrão, Vitor Hugo, Pai, Emil F, Batey, Robert A, Gray-Owen, Scott D, Houry, Walid A
Published in ACS infectious diseases (11.12.2020)
Published in ACS infectious diseases (11.12.2020)
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Journal Article
Potent ClpP agonists with anticancer properties bind the protease with improved structural complementarity and alter the mitochondrial N-terminome
Mabanglo, Mark F., Wong, Keith S., Barghash, Marim M., Leung, Elisa, Chuang, Stephanie H. W., Ardalan, Afshan, Majaesic, Emily M., Wong, Cassandra J., Zhang, Shen, Lang, Henk, Karanewsky, Donald S., Iwanowicz, Andrew A., Graves, Lee M., Iwanowicz, Edwin J., Gingras, Anne-Claude, Houry, Walid A.
Published in Structure (London) (15.12.2022)
Published in Structure (London) (15.12.2022)
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Journal Article
Abstract 3843: Potent human ClpP protease agonists with anticancer properties bind the enzyme with improved structural complementarity and alter the mitochondrial N-terminome
Mabanglo, Mark F., Wong, Keith S., Barghash, Marim M., Graves, Lee M., Iwanowicz, Edwin J., Houry, Walid A.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli: e1004120
Babu, Mohan, Arnold, Roland, Bundalovic-Torma, Cedoljub, Gagarinova, Alla, Wong, Keith S, Kumar, Ashwani, Stewart, Geordie, Samanfar, Bahram, Aoki, Hiroyuki, Wagih, Omar, Vlasblom, James, Phanse, Sadhna, Lad, Krunal, Yu, Angela YeouHsiung, Graham, Christopher, Jin, Ke, Brown, Eric, Golshani, Ashkan, Kim, Philip, Moreno-Hagelsieb, Gabriel, Greenblatt, Jack, Houry, Walid A, Parkinson, John, Emili, Andrew
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
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Journal Article
METHODS FOR TREATING CANCER WITH ACYLDEPSIPEPTIDE ANALOGS
Wong, Keith S, Batey, Robert A, Goodreid, Jordan D, Mabanglo, Mark F, Houry, Walid A
Year of Publication 10.06.2021
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Year of Publication 10.06.2021
Patent
METHODS FOR TREATING CANCER WITH ACYLDEPSIPEPTIDE ANALOGS
MABANGLO, MARK F, BATEY, ROBERT A, HOURY, WALID A, WONG, KEITH S, GOODREID, JORDAN D
Year of Publication 05.12.2019
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Year of Publication 05.12.2019
Patent