MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis
Chan, Kui Ming, Wong, Hoi Leong Xavier, Jin, Guoxiang, Liu, Baohua, Cao, Renhai, Cao, Yihai, Lehti, Kaisa, Tryggvason, Karl, Zhou, Zhongjun
Published in Developmental cell (12.06.2012)
Published in Developmental cell (12.06.2012)
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PMI-controlled mannose metabolism and glycosylation determines tissue tolerance and virus fitness
Liang, Ronghui, Ye, Zi-Wei, Qin, Zhenzhi, Xie, Yubin, Yang, Xiaomeng, Sun, Haoran, Du, Qiaohui, Luo, Peng, Tang, Kaiming, Hu, Bodan, Cao, Jianli, Wong, Xavier Hoi-Leong, Ling, Guang-Sheng, Chu, Hin, Shen, Jiangang, Yin, Feifei, Jin, Dong-Yan, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung, Yuan, Shuofeng
Published in Nature communications (08.03.2024)
Published in Nature communications (08.03.2024)
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Journal Article
Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling
Wong, Hoi Leong Xavier, Qin, Hong-Yan, Tsang, Siu Wai, Zuo, Xiao, Che, Sijia, Chow, Chi Fung Willis, Li, Xi, Xiao, Hai-Tao, Zhao, Ling, Huang, Tao, Lin, Cheng Yuan, Kwan, Hiu Yee, Yang, Tao, Longo, Frank M, Lyu, Aiping, Bian, Zhao-Xiang
Published in Nature communications (15.04.2019)
Published in Nature communications (15.04.2019)
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Journal Article
Enterochromaffin cell hyperplasia in the gut: Factors, mechanism and therapeutic clues
Qin, Hong-yan, Xavier Wong, Hoi Leong, Zang, Kai-hong, Li, Xun, Bian, Zhao-xiang
Published in Life sciences (1973) (15.12.2019)
Published in Life sciences (1973) (15.12.2019)
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Journal Article
Toll-like receptor 4 is a master regulator for colorectal cancer growth under high-fat diet by programming cancer metabolism
Hu, Xianjing, Fatima, Sarwat, Chen, Minting, Xu, Keyang, Huang, Chunhua, Gong, Rui-Hong, Su, Tao, Wong, Hoi Leong Xavier, Bian, Zhaoxiang, Kwan, Hiu Yee
Published in Cell death & disease (12.08.2021)
Published in Cell death & disease (12.08.2021)
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Journal Article
Dihydroartemisinin is potential therapeutics for treating late-stage CRC by targeting the elevated c-Myc level
Hu, Xianjing, Fatima, Sarwat, Chen, Minting, Huang, Tao, Chen, Yuen Wa, Gong, Ruihong, Wong, Hoi Leong Xavier, Yu, Rongmin, Song, Liyan, Kwan, Hiu Yee, Bian, Zhaoxiang
Published in Cell death & disease (05.11.2021)
Published in Cell death & disease (05.11.2021)
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Journal Article
Palmitic acid is an intracellular signaling molecule involved in disease development
Fatima, Sarwat, Hu, Xianjing, Gong, Rui-Hong, Huang, Chunhua, Chen, Minting, Wong, Hoi Leong Xavier, Bian, Zhaoxiang, Kwan, Hiu Yee
Published in Cellular and molecular life sciences : CMLS (01.07.2019)
Published in Cellular and molecular life sciences : CMLS (01.07.2019)
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Journal Article
Gut-Microbial Metabolites, Probiotics and Their Roles in Type 2 Diabetes
Zhai, Lixiang, Wu, Jiayan, Lam, Yan Y, Kwan, Hiu Yee, Bian, Zhao-Xiang, Wong, Hoi Leong Xavier
Published in International journal of molecular sciences (27.11.2021)
Published in International journal of molecular sciences (27.11.2021)
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Journal Article
Gut microbiota-derived tryptamine and phenethylamine impair insulin sensitivity in metabolic syndrome and irritable bowel syndrome
Zhai, Lixiang, Xiao, Haitao, Lin, Chengyuan, Wong, Hoi Leong Xavier, Lam, Yan Y, Gong, Mengxue, Wu, Guojun, Ning, Ziwan, Huang, Chunhua, Zhang, Yijing, Yang, Chao, Luo, Jingyuan, Zhang, Lu, Zhao, Ling, Zhang, Chenhong, Lau, Johnson Yiu-Nam, Lu, Aiping, Lau, Lok-Ting, Jia, Wei, Zhao, Liping, Bian, Zhao-Xiang
Published in Nature communications (17.08.2023)
Published in Nature communications (17.08.2023)
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Journal Article
Regulation of age-associated insulin resistance by MT1-MMP-mediated cleavage of insulin receptor
Guo, Xuanming, Asthana, Pallavi, Gurung, Susma, Zhang, Shuo, Wong, Sheung Kin Ken, Fallah, Samane, Chow, Chi Fung Willis, Che, Sijia, Zhai, Lixiang, Wang, Zening, Ge, Xin, Jiang, Zhixin, Wu, Jiayan, Zhang, Yijing, Wu, Xiaoyu, Xu, Keyang, Lin, Cheng Yuan, Kwan, Hiu Yee, Lyu, Aiping, Zhou, Zhongjun, Bian, Zhao-Xiang, Wong, Hoi Leong Xavier
Published in Nature communications (29.06.2022)
Published in Nature communications (29.06.2022)
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Journal Article
Saturated long-chain fatty acid-producing bacteria contribute to enhanced colonic motility in rats
Zhao, Ling, Huang, Yufen, Lu, Lin, Yang, Wei, Huang, Tao, Lin, Zesi, Lin, Chengyuan, Kwan, Hiuyee, Wong, Hoi Leong Xavier, Chen, Yang, Sun, Silong, Xie, Xuefeng, Fang, Xiaodong, Yang, Huanming, Wang, Jian, Zhu, Lixin, Bian, Zhaoxiang
Published in Microbiome (14.06.2018)
Published in Microbiome (14.06.2018)
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Journal Article
Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2
Guo, Xuanming, Cao, Jianli, Cai, Jian-Piao, Wu, Jiayan, Huang, Jiangang, Asthana, Pallavi, Wong, Sheung Kin Ken, Ye, Zi-Wei, Gurung, Susma, Zhang, Yijing, Wang, Sheng, Wang, Zening, Ge, Xin, Kwan, Hiu Yee, Lyu, Aiping, Chan, Kui Ming, Wong, Nathalie, Huang, Jiandong, Zhou, Zhongjun, Bian, Zhao-Xiang, Yuan, Shuofeng, Wong, Hoi Leong Xavier
Published in Nature communications (23.12.2022)
Published in Nature communications (23.12.2022)
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Journal Article
High-fat diet feeding and palmitic acid increase CRC growth in β2AR-dependent manner
Fatima, Sarwat, Hu, Xianjing, Huang, Chunhua, Zhang, Weixiong, Cai, Jing, Huang, Min, Gong, Rui-Hong, Chen, Minting, Ho, Alan H M, Su, Tao, Wong, Hoi Leong Xavier, Bian, Zhaoxiang, Kwan, Hiu Yee
Published in Cell death & disease (26.09.2019)
Published in Cell death & disease (26.09.2019)
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Journal Article
Artesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis
Guo, Xuanming, Asthana, Pallavi, Zhai, Lixiang, Cheng, Ka Wing, Gurung, Susma, Huang, Jiangang, Wu, Jiayan, Zhang, Yijing, Mahato, Arun Kumar, Saarma, Mart, Ustav, Mart, Kwan, Hiu Yee, Lyu, Aiping, Chan, Kui Ming, Xu, Pingyi, Bian, Zhao-Xiang, Wong, Hoi Leong Xavier
Published in Nature communications (03.02.2024)
Published in Nature communications (03.02.2024)
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Journal Article
Combination of artesunate and WNT974 induces KRAS protein degradation by upregulating E3 ligase ANACP2 and β-TrCP in the ubiquitin-proteasome pathway
Gong, Rui-Hong, Chen, Minting, Huang, Chunhua, Wong, Hoi Leong Xavier, Kwan, Hiu Yee, Bian, Zhaoxiang
Published in Cell communication and signaling (19.03.2022)
Published in Cell communication and signaling (19.03.2022)
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Journal Article
IDDF2022-ABS-0035 Pathogenetic role of GUT microbiota shunting of dietary phenylalanine to phenethylamine in diarrhea-predominant irritable bowel syndrome
Zhai, Lixiang, Huang, Chunhua, Ning, Ziwan, Zhang, Yijing, Zhuang, Min, Yang, Wei, Wang, Xiaolei, Wang, Jingjing, Zhang, Eric Lu, Xiao, Haitao, Zhao, Ling, Lam, Yan Y, Willis Chow, Chi-Fung, Huang, Jiandong, Yuan, Shuofeng, Chan, Kui-Ming, Yuan, Chun-Su, Lau, Johnson Yiu-Nam, Xavier Wong, Hoi-Leong, Bian, Zhao-Xiang
Published in Gut (02.09.2022)
Published in Gut (02.09.2022)
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Baicalein is a novel TLR4‐targeting therapeutics agent that inhibits TLR4/HIF‐1α/VEGF signaling pathway in colorectal cancer
Chen, Minting, Zhong, Keying, Tan, Jincheng, Meng, Mingjing, Liu, Chok Mei, Chen, Baisen, Huang, Chunhua, Wong, Hoi Leong Xavier, Bian, Zhaoxiang, Su, Tao, Kwan, Hiu Yee
Published in Clinical and translational medicine (01.11.2021)
Published in Clinical and translational medicine (01.11.2021)
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Journal Article
Berberine Suppresses Colonic Inflammation in Dextran Sulfate Sodium-Induced Murine Colitis Through Inhibition of Cytosolic Phospholipase A2 Activity
Zhai, Lixiang, Huang, Tao, Xiao, Hai-Tao, Wu, Pei-Gen, Lin, Cheng-Yuan, Ning, Zi-Wan, Zhao, Ling, Kwan, Hiu Yee Anna, Hu, Xian-Jing, Wong, Hoi Leong Xavier, Li, Xian-Qian, Bian, Zhao-Xiang
Published in Frontiers in pharmacology (19.11.2020)
Published in Frontiers in pharmacology (19.11.2020)
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Journal Article
Signal transducer and activator of transcription-3 drives the high-fat diet-associated prostate cancer growth
Kwan, Hiu Yee, Liu, Bin, Huang, Chunhua, Fatima, Sarwat, Su, Tao, Zhao, Xiaoshan, Ho, Alan H M, Han, Quanbin, Hu, Xianjing, Gong, Rui-Hong, Chen, Minting, Wong, Hoi Leong Xavier, Bian, Zhaoxiang
Published in Cell death & disease (02.09.2019)
Published in Cell death & disease (02.09.2019)
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