Basic Mechanisms Responsible for Osteolytic and Osteoblastic Bone Metastases
GUISE, Theresa A, MOHAMMAD, Khalid S, CHIRGWIN, John M, CLINES, Gregory, STEBBINS, Elizabeth G, WONG, Darren H, HIGGINS, Linda S, VESSELLA, Robert, COREY, Eva, PADALECKI, Susan, SUVA, Larry
Published in Clinical cancer research (15.10.2006)
Published in Clinical cancer research (15.10.2006)
Get full text
Journal Article
Conference Proceeding
Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone
Mohammad, Khalid S, Chen, Carol G, Balooch, Guive, Stebbins, Elizabeth, McKenna, C Ryan, Davis, Holly, Niewolna, Maria, Peng, Xiang Hong, Nguyen, Daniel H N, Ionova-Martin, Sophi S, Bracey, John W, Hogue, William R, Wong, Darren H, Ritchie, Robert O, Suva, Larry J, Derynck, Rik, Guise, Theresa A, Alliston, Tamara
Published in PloS one (16.04.2009)
Published in PloS one (16.04.2009)
Get full text
Journal Article
Knockdown of β-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo
Dudek, Henryk, Wong, Darren H, Arvan, Rokhand, Shah, Anee, Wortham, Kathleen, Ying, Bo, Diwanji, Rohan, Zhou, Wei, Holmes, Benjamin, Yang, Hailin, Cyr, Wendy A, Zhou, Yi, Shah, Aalok, Farkiwala, Ruchir, Lee, Michael, Li, Yiting, Rettig, Garrett R, Collingwood, Michael A, Basu, Sujit K, Behlke, Mark A, Brown, Bob D
Published in Molecular therapy (01.01.2014)
Published in Molecular therapy (01.01.2014)
Get full text
Journal Article
SD-208, a novel transforming growth factor β receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo
UHL, Martin, AULWURM, Steffen, MURPHY, Alison, WONG, Darren H, WICK, Wolfgang, HIGGINS, Linda S, WELLER, Michael, WISCHHUSEN, Jörg, WEILER, Markus, JING YING MA, ALMIREZ, Ramona, MANGADU, Ruban, LIU, Yu-Wang, PLATTEN, Michael, HERRLINGER, Ulrich
Published in Cancer research (Chicago, Ill.) (01.11.2004)
Published in Cancer research (Chicago, Ill.) (01.11.2004)
Get full text
Journal Article
Temozolomide analogs with improved brain/plasma ratios – Exploring the possibility of enhancing the therapeutic index of temozolomide
Rai, Roopa, Banerjee, Monali, Wong, Darren H., McCullagh, Emma, Gupta, Ashu, Tripathi, Shailendra, Riquelme, Eduardo, Jangir, Ramnivas, Yadav, Shyamraj, Raja, Mohd, Melkani, Pankaj, Dixit, Vikas, Patil, Umesh, Shrivastava, Ritesh, Middya, Sandip, Olivares, Felipe, Guerrero, Javier, Surya, Arjun, Pham, Son M., Bernales, Sebastián, Protter, Andrew A., Hung, David T., Chakravarty, Sarvajit
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
Get full text
Journal Article
Inhibition of transforming growth factor beta signaling reduces pancreatic adenocarcinoma growth and invasiveness
Gaspar, Nicholas J, Li, Lingyun, Kapoun, Ann M, Medicherla, Satyanarayana, Reddy, Mamatha, Li, Georgia, O'Young, Gilbert, Quon, Diana, Henson, Margaret, Damm, Deborah L, Muiru, Gladys T, Murphy, Alison, Higgins, Linda S, Chakravarty, Sarvajit, Wong, Darren H
Published in Molecular pharmacology (01.07.2007)
Published in Molecular pharmacology (01.07.2007)
Get full text
Journal Article
Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model
Tran, Thomas-Toan, Uhl, Martin, Ma, Jing Ying, Janssen, Lisa, Sriram, Venkataraman, Aulwurm, Steffen, Kerr, Irene, Lam, Andrew, Webb, Heather K, Kapoun, Ann M, Kizer, Darin E, McEnroe, Glenn, Hart, Barry, Axon, Jonathan, Murphy, Alison, Chakravarty, Sarvajit, Dugar, Sundeep, Protter, Andrew A, Higgins, Linda S, Wick, Wolfgang, Weller, Michael, Wong, Darren H
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2007)
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2007)
Get full text
Journal Article
Antitumor Activity of TGF-β Inhibitor is Dependent on the Microenvironment
MEDICHERLA, Satyanarayana, LINGYUN LI, WONG, Darren H, HIGGINS, Linda S, JING YING MA, KAPOUN, Ann M, GASPAR, Nicholas J, LIU, Yu-Wang, MANGADU, Ruban, O'YOUNG, Gilbert, PROTTER, Andrew A, SCHREINER, George F
Published in Anticancer research (01.11.2007)
Get full text
Published in Anticancer research (01.11.2007)
Journal Article
Biochemical Studies of Zmpste24-deficient Mice
Leung, G K, Schmidt, W K, Bergo, M O, Gavino, B, Wong, D H, Tam, A, Ashby, M N, Michaelis, S, Young, S G
Published in The Journal of biological chemistry (03.08.2001)
Published in The Journal of biological chemistry (03.08.2001)
Get full text
Journal Article
Studies with Recombinant Saccharomyces cerevisiae CaaX Prenyl Protease Rce1p
Dolence, Julia M, Steward, Lance E, Dolence, E. Kurt, Wong, Darren H, Poulter, C. Dale
Published in Biochemistry (Easton) (11.04.2000)
Published in Biochemistry (Easton) (11.04.2000)
Get full text
Journal Article
Peptidic 1-cyanopyrrolidines: synthesis and SAR of a series of potent, selective cathepsin inhibitors
Rydzewski, Robert M, Bryant, Clifford, Oballa, Renata, Wesolowski, Gregg, Rodan, Sevgi B, Bass, Kathryn E, Wong, Darren H
Published in Bioorganic & medicinal chemistry (01.10.2002)
Published in Bioorganic & medicinal chemistry (01.10.2002)
Get full text
Journal Article
Knockdown of [beta]-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo
Dudek, Henryk, Wong, Darren H, Arvan, Rokhand, Shah, Anee, Wortham, Kathleen, Ying, Bo, Diwanji, Rohan, Zhou, Wei, Holmes, Benjamin, Yang, Hailin, Cyr, Wendy A, Zhou, Yi, Shah, Aalok, Farkiwala, Ruchir, Lee, Michael, Li, Yiting, Rettig, Garrett R, Collingwood, Michael A, Basu, Sujit K, Behlke, Mark A, Brown, Bob D
Published in Molecular therapy (01.01.2014)
Published in Molecular therapy (01.01.2014)
Get full text
Journal Article
Pharmacologic Inhibition of the TGF-[beta] Type I Receptor Kinase Has Anabolic and Anti-Catabolic Effects on Bone
Mohammad, Khalid S, Chen, Carol G, Balooch, Guive, Stebbins, Elizabeth, McKenna, C. Ryan, Davis, Holly, Niewolna, Maria, Peng, Xiang Hong, Nguyen, Daniel H. N, Ionova-Martin, Sophi S, Bracey, John W, Hogue, William R, Wong, Darren H, Ritchie, Robert O, Suva, Larry J, Derynck, Rik, Guise, Theresa A, Alliston, Tamara
Published in PloS one (16.04.2009)
Published in PloS one (16.04.2009)
Get full text
Journal Article
Inhibition of Transforming Growth Factor β Signaling Reduces Pancreatic Adenocarcinoma Growth and Invasiveness
Nicholas J. Gaspar, Lingyun Li, Ann M. Kapoun, Satyanarayana Medicherla, Mamatha Reddy, Georgia Li, Gilbert O'Young, Diana Quon, Margaret Henson, Deborah L. Damm, Gladys T. Muiru, Alison Murphy, Linda S. Higgins, Sarvajit Chakravarty, Darren H. Wong
Published in Molecular pharmacology (01.07.2007)
Published in Molecular pharmacology (01.07.2007)
Get full text
Journal Article