RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2
Chen, Mengnuo, Wei, Lai, Law, Cheuk‐Ting, Tsang, Felice Ho‐Ching, Shen, Jialing, Cheng, Carol Lai‐Hung, Tsang, Long‐Hin, Ho, Daniel Wai‐Hung, Chiu, David Kung‐Chun, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin, Wong, Chun‐Ming
Published in Hepatology (Baltimore, Md.) (01.06.2018)
Published in Hepatology (Baltimore, Md.) (01.06.2018)
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Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC
Wei, Lai, Lee, Derek, Law, Cheuk-Ting, Zhang, Misty Shuo, Shen, Jialing, Chin, Don Wai-Ching, Zhang, Allen, Tsang, Felice Ho-Ching, Wong, Ceci Lok-Sze, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui, Wong, Chun-Ming
Published in Nature communications (15.10.2019)
Published in Nature communications (15.10.2019)
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Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
Chiu, David Kung-Chun, Tse, Aki Pui-Wah, Xu, Iris Ming-Jing, Di Cui, Jane, Lai, Robin Kit-Ho, Li, Lynna Lan, Koh, Hui-Yu, Tsang, Felice Ho-Ching, Wei, Larry Lai, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Nature communications (11.09.2017)
Published in Nature communications (11.09.2017)
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Hypoxia induces myeloid‐derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C‐C motif) ligand 26
Chiu, David Kung‐Chun, Xu, Iris Ming‐Jing, Lai, Robin Kit‐Ho, Tse, Aki Pui‐Wah, Wei, Larry Lai, Koh, Hui‐Yu, Li, Lynna Lan, Lee, Derek, Lo, Regina Cheuk‐Lam, Wong, Chun‐Ming, Ng, Irene Oi‐Lin, Wong, Carmen Chak‐Lui
Published in Hepatology (Baltimore, Md.) (01.09.2016)
Published in Hepatology (Baltimore, Md.) (01.09.2016)
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Aberrant Super‐Enhancer Landscape in Human Hepatocellular Carcinoma
Tsang, Felice Ho‐Ching, Law, Cheuk‐Ting, Tang, Tsz‐Ching Chloe, Cheng, Carol Lai‐Hung, Chin, Don Wai‐Ching, Tam, Wing‐Sum Vincy, Wei, Lai, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin, Wong, Chun‐Ming
Published in Hepatology (Baltimore, Md.) (01.06.2019)
Published in Hepatology (Baltimore, Md.) (01.06.2019)
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Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma
Lee, Derek, Xu, Iris Ming‐Jing, Chiu, David Kung‐Chun, Leibold, Josef, Tse, Aki Pui‐Wah, Bao, Macus Hao‐Ran, Yuen, Vincent Wai‐Hin, Chan, Cerise Yuen‐Ki, Lai, Robin Kit‐Ho, Chin, Don Wai‐Ching, Chan, Daniel For‐Fan, Cheung, Tan‐To, Chok, Siu‐Ho, Wong, Chun‐Ming, Lowe, Scott W., Ng, Irene Oi‐Lin, Wong, Carmen Chak‐Lui
Published in Hepatology (Baltimore, Md.) (01.04.2019)
Published in Hepatology (Baltimore, Md.) (01.04.2019)
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Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer
Zhang, Misty Shuo, Cui, Jane Di, Lee, Derek, Yuen, Vincent Wai-Hin, Chiu, David Kung-Chun, Goh, Chi Ching, Cheu, Jacinth Wing-Sum, Tse, Aki Pui-Wah, Bao, Macus Hao-Ran, Wong, Bowie Po Yee, Chen, Carrie Yiling, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Nature communications (17.02.2022)
Published in Nature communications (17.02.2022)
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Decoding the Roles of Long Noncoding RNAs in Hepatocellular Carcinoma
Wong, Lok-Sze, Wong, Chun-Ming
Published in International journal of molecular sciences (19.03.2021)
Published in International journal of molecular sciences (19.03.2021)
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Journal Article
Up‐regulation of histone methyltransferase SETDB1 by multiple mechanisms in hepatocellular carcinoma promotes cancer metastasis
Wong, Chun‐Ming, Wei, Lai, Law, Cheuk‐Ting, Ho, Daniel Wai‐Hung, Tsang, Felice Ho‐Ching, Au, Sandy Leung‐Kuen, Sze, Karen Man‐Fong, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.02.2016)
Published in Hepatology (Baltimore, Md.) (01.02.2016)
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RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2
Wang, Xia, Wang, Jin, Tsui, Yu-Man, Shi, Chaoran, Wang, Ying, Zhang, Xin, Yan, Qian, Chen, Miao, Jiang, Chen, Yuan, Yun-Fei, Wong, Chun-Ming, Liu, Ming, Feng, Zeng-Yu, Chen, Honglin, Ng, Irene Oi Lin, Jiang, Lingxi, Guan, Xin-Yuan
Published in Nature communications (09.03.2021)
Published in Nature communications (09.03.2021)
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Lysyl oxidase‐like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma
Wong, Carmen Chak‐Lui, Tse, Aki Pui‐Wah, Huang, Yan‐Ping, Zhu, Yan‐Ting, Chiu, David Kung‐Chun, Lai, Robin Kit‐Ho, Au, Sandy Leung‐Kuen, Kai, Alan Ka‐Lun, Lee, Joyce Man‐Fong, Wei, Larry Lai, Tsang, Felice Ho‐Ching, Lo, Regina Cheuk‐Lam, Shi, Jue, Zheng, Yong‐Ping, Wong, Chun‐Ming, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.11.2014)
Published in Hepatology (Baltimore, Md.) (01.11.2014)
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HELLS Regulates Chromatin Remodeling and Epigenetic Silencing of Multiple Tumor Suppressor Genes in Human Hepatocellular Carcinoma
Law, Cheuk‐Ting, Wei, Lai, Tsang, Felice Ho‐Ching, Chan, Cerise Yuen‐Ki, Xu, Iris Ming‐Jing, Lai, Robin Kit‐Ho, Ho, Daniel Wai‐Hung, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin, Wong, Chun‐Ming
Published in Hepatology (Baltimore, Md.) (01.05.2019)
Published in Hepatology (Baltimore, Md.) (01.05.2019)
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Transketolase counteracts oxidative stress to drive cancer development
Xu, Iris Ming-Jing, Lai, Robin Kit-Ho, Lin, Shu-Hai, Tse, Aki Pui-Wah, Chiu, David Kung-Chun, Koh, Hui-Yu, Law, Cheuk-Ting, Wong, Chun-Ming, Cai, Zongwei, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2016)
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Journal Article
Histone methyltransferase G9a promotes liver cancer development by epigenetic silencing of tumor suppressor gene RARRES3
Wei, Lai, Chiu, David Kung-Chun, Tsang, Felice Ho-Ching, Law, Dicky Cheuk-Ting, Cheng, Carol Lai-Hung, Au, Sandy Leung-Kuen, Lee, Joyce Man-Fong, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin, Wong, Chun-Ming
Published in Journal of hepatology (01.10.2017)
Published in Journal of hepatology (01.10.2017)
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Journal Article
Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway
Kung-Chun Chiu, David, Pui-Wah Tse, Aki, Law, Cheuk-Ting, Ming-Jing Xu, Iris, Lee, Derek, Chen, Mengnuo, Kit-Ho Lai, Robin, Wai-Hin Yuen, Vincent, Wing-Sum Cheu, Jacinth, Wai-Hung Ho, Daniel, Wong, Chun-Ming, Zhang, Huafeng, Oi-Lin Ng, Irene, Chak-Lui Wong, Carmen
Published in Cell death & disease (09.12.2019)
Published in Cell death & disease (09.12.2019)
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Journal Article
Down‐regulation of TIMP2 by HIF‐1α/miR‐210/HIF‐3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma
Kai, Alan Ka‐Lun, Chan, Lo Kong, Lo, Regina Cheuk‐Lam, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Wong, Jack Chun‐Ming, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.08.2016)
Published in Hepatology (Baltimore, Md.) (01.08.2016)
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Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
Wong, Carmen Chak-Lui, Gilkes, Daniele M., Zhang, Huafeng, Chen, Jasper, Wei, Hong, Chaturvedi, Pallavi, Fraley, Stephanie I., Wong, Chun-Ming, Khoo, Ui-Soon, Ng, Irene Oi-Lin, Wirtz, Denis, Semenza, Gregg L.
Published in Proceedings of the National Academy of Sciences - PNAS (27.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (27.09.2011)
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Journal Article
Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis
Au, Sandy Leung-Kuen, Wong, Carmen Chak-Lui, Lee, Joyce Man-Fong, Fan, Dorothy Ngo-Yin, Tsang, Felice Hoching, Ng, Irene Oi-Lin, Wong, Chun-Ming
Published in Hepatology (Baltimore, Md.) (01.08.2012)
Published in Hepatology (Baltimore, Md.) (01.08.2012)
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