Loading…
Loading…
RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2
Chen, Mengnuo, Wei, Lai, Law, Cheuk‐Ting, Tsang, Felice Ho‐Ching, Shen, Jialing, Cheng, Carol Lai‐Hung, Tsang, Long‐Hin, Ho, Daniel Wai‐Hung, Chiu, David Kung‐Chun, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin, Wong, Chun‐Ming
Published in Hepatology (Baltimore, Md.) (01.06.2018)
Published in Hepatology (Baltimore, Md.) (01.06.2018)
Get full text
Journal Article
Loading…
Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC
Wei, Lai, Lee, Derek, Law, Cheuk-Ting, Zhang, Misty Shuo, Shen, Jialing, Chin, Don Wai-Ching, Zhang, Allen, Tsang, Felice Ho-Ching, Wong, Ceci Lok-Sze, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui, Wong, Chun-Ming
Published in Nature communications (15.10.2019)
Published in Nature communications (15.10.2019)
Get full text
Journal Article
Loading…
Loading…
Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
Chiu, David Kung-Chun, Tse, Aki Pui-Wah, Xu, Iris Ming-Jing, Di Cui, Jane, Lai, Robin Kit-Ho, Li, Lynna Lan, Koh, Hui-Yu, Tsang, Felice Ho-Ching, Wei, Larry Lai, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Nature communications (11.09.2017)
Published in Nature communications (11.09.2017)
Get full text
Journal Article
Loading…
Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer
Zhang, Misty Shuo, Cui, Jane Di, Lee, Derek, Yuen, Vincent Wai-Hin, Chiu, David Kung-Chun, Goh, Chi Ching, Cheu, Jacinth Wing-Sum, Tse, Aki Pui-Wah, Bao, Macus Hao-Ran, Wong, Bowie Po Yee, Chen, Carrie Yiling, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Nature communications (17.02.2022)
Published in Nature communications (17.02.2022)
Get full text
Journal Article
Loading…
Hypoxia induces myeloid‐derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C‐C motif) ligand 26
Chiu, David Kung‐Chun, Xu, Iris Ming‐Jing, Lai, Robin Kit‐Ho, Tse, Aki Pui‐Wah, Wei, Larry Lai, Koh, Hui‐Yu, Li, Lynna Lan, Lee, Derek, Lo, Regina Cheuk‐Lam, Wong, Chun‐Ming, Ng, Irene Oi‐Lin, Wong, Carmen Chak‐Lui
Published in Hepatology (Baltimore, Md.) (01.09.2016)
Published in Hepatology (Baltimore, Md.) (01.09.2016)
Get full text
Journal Article
Loading…
Aberrant Super‐Enhancer Landscape in Human Hepatocellular Carcinoma
Tsang, Felice Ho‐Ching, Law, Cheuk‐Ting, Tang, Tsz‐Ching Chloe, Cheng, Carol Lai‐Hung, Chin, Don Wai‐Ching, Tam, Wing‐Sum Vincy, Wei, Lai, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin, Wong, Chun‐Ming
Published in Hepatology (Baltimore, Md.) (01.06.2019)
Published in Hepatology (Baltimore, Md.) (01.06.2019)
Get full text
Journal Article
Loading…
Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma
Lee, Derek, Xu, Iris Ming‐Jing, Chiu, David Kung‐Chun, Leibold, Josef, Tse, Aki Pui‐Wah, Bao, Macus Hao‐Ran, Yuen, Vincent Wai‐Hin, Chan, Cerise Yuen‐Ki, Lai, Robin Kit‐Ho, Chin, Don Wai‐Ching, Chan, Daniel For‐Fan, Cheung, Tan‐To, Chok, Siu‐Ho, Wong, Chun‐Ming, Lowe, Scott W., Ng, Irene Oi‐Lin, Wong, Carmen Chak‐Lui
Published in Hepatology (Baltimore, Md.) (01.04.2019)
Published in Hepatology (Baltimore, Md.) (01.04.2019)
Get full text
Journal Article
Loading…
RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2
Wang, Xia, Wang, Jin, Tsui, Yu-Man, Shi, Chaoran, Wang, Ying, Zhang, Xin, Yan, Qian, Chen, Miao, Jiang, Chen, Yuan, Yun-Fei, Wong, Chun-Ming, Liu, Ming, Feng, Zeng-yu, Chen, Honglin, Ng, Irene Oi Lin, Jiang, Lingxi, Guan, Xin-Yuan
Published in Nature communications (09.03.2021)
Published in Nature communications (09.03.2021)
Get full text
Journal Article
Loading…
Up‐regulation of histone methyltransferase SETDB1 by multiple mechanisms in hepatocellular carcinoma promotes cancer metastasis
Wong, Chun‐Ming, Wei, Lai, Law, Cheuk‐Ting, Ho, Daniel Wai‐Hung, Tsang, Felice Ho‐Ching, Au, Sandy Leung‐Kuen, Sze, Karen Man‐Fong, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.02.2016)
Published in Hepatology (Baltimore, Md.) (01.02.2016)
Get full text
Journal Article
Loading…
Lysyl oxidase‐like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma
Wong, Carmen Chak‐Lui, Tse, Aki Pui‐Wah, Huang, Yan‐Ping, Zhu, Yan‐Ting, Chiu, David Kung‐Chun, Lai, Robin Kit‐Ho, Au, Sandy Leung‐Kuen, Kai, Alan Ka‐Lun, Lee, Joyce Man‐Fong, Wei, Larry Lai, Tsang, Felice Ho‐Ching, Lo, Regina Cheuk‐Lam, Shi, Jue, Zheng, Yong‐Ping, Wong, Chun‐Ming, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.11.2014)
Published in Hepatology (Baltimore, Md.) (01.11.2014)
Get full text
Journal Article
Loading…
HELLS Regulates Chromatin Remodeling and Epigenetic Silencing of Multiple Tumor Suppressor Genes in Human Hepatocellular Carcinoma
Law, Cheuk‐Ting, Wei, Lai, Tsang, Felice Ho‐Ching, Chan, Cerise Yuen‐Ki, Xu, Iris Ming‐Jing, Lai, Robin Kit‐Ho, Ho, Daniel Wai‐Hung, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin, Wong, Chun‐Ming
Published in Hepatology (Baltimore, Md.) (01.05.2019)
Published in Hepatology (Baltimore, Md.) (01.05.2019)
Get full text
Journal Article
Loading…
Transketolase counteracts oxidative stress to drive cancer development
Xu, Iris Ming-Jing, Lai, Robin Kit-Ho, Lin, Shu-Hai, Tse, Aki Pui-Wah, Chiu, David Kung-Chun, Koh, Hui-Yu, Law, Cheuk-Ting, Wong, Chun-Ming, Cai, Zongwei, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2016)
Get full text
Journal Article
Loading…
Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway
Kung-Chun Chiu, David, Pui-Wah Tse, Aki, Law, Cheuk-Ting, Ming-Jing Xu, Iris, Lee, Derek, Chen, Mengnuo, Kit-Ho Lai, Robin, Wai-Hin Yuen, Vincent, Wing-Sum Cheu, Jacinth, Wai-Hung Ho, Daniel, Wong, Chun-Ming, Zhang, Huafeng, Ng, Irene Oi-Lin, Chak-Lui Wong, Carmen
Published in Cell death & disease (09.12.2019)
Published in Cell death & disease (09.12.2019)
Get full text
Journal Article
Loading…
Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis
Au, Sandy Leung-Kuen, Wong, Carmen Chak-Lui, Lee, Joyce Man-Fong, Fan, Dorothy Ngo-Yin, Tsang, Felice Hoching, Ng, Irene Oi-Lin, Wong, Chun-Ming
Published in Hepatology (Baltimore, Md.) (01.08.2012)
Published in Hepatology (Baltimore, Md.) (01.08.2012)
Get full text
Journal Article
Loading…
Histone methyltransferase G9a promotes liver cancer development by epigenetic silencing of tumor suppressor gene RARRES3
Wei, Lai, Chiu, David Kung-Chun, Tsang, Felice Ho-Ching, Law, Cheuk-Ting, Cheng, Carol Lai-Hung, Au, Sandy Leung-Kuen, Lee, Joyce Man-Fong, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin, Wong, Chun-Ming
Published in Journal of hepatology (01.10.2017)
Published in Journal of hepatology (01.10.2017)
Get full text
Journal Article
Loading…
Down‐regulation of TIMP2 by HIF‐1α/miR‐210/HIF‐3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma
Kai, Alan Ka‐Lun, Chan, Lo Kong, Lo, Regina Cheuk‐Lam, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Wong, Jack Chun‐Ming, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.08.2016)
Published in Hepatology (Baltimore, Md.) (01.08.2016)
Get full text
Journal Article
Loading…
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
Wong, Carmen Chak-Lui, Gilkes, Daniele M., Zhang, Huafeng, Chen, Jasper, Wei, Hong, Chaturvedi, Pallavi, Fraley, Stephanie I., Wong, Chun-Ming, Khoo, Ui-Soon, Ng, Irene Oi-Lin, Wirtz, Denis, Semenza, Gregg L.
Published in Proceedings of the National Academy of Sciences - PNAS (27.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (27.09.2011)
Get full text
Journal Article
Loading…
MicroRNA‐125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2
Liang, Linhui, Wong, Chun‐Ming, Ying, Qiao, Fan, Dorothy Ngo‐Yin, Huang, Shenglin, Ding, Jie, Yao, Jian, Yan, Mingxia, Li, Jinjun, Yao, Ming, Ng, Irene Oi‐Lin, He, Xianghuo
Published in Hepatology (Baltimore, Md.) (01.11.2010)
Published in Hepatology (Baltimore, Md.) (01.11.2010)
Get full text
Journal Article