Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis
Thelen, Melanie, Damme, Markus, Daμμe, Markus, Schweizer, Michaela, Hagel, Christian, Wong, Andrew M S, Cooper, Jonathan D, Braulke, Thomas, Galliciotti, Giovanna
Published in PloS one (20.04.2012)
Published in PloS one (20.04.2012)
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Intravenous administration of AAV2/9 to the fetal and neonatal mouse leads to differential targeting of CNS cell types and extensive transduction of the nervous system
Rahim, Ahad A, Wong, Andrew M S, Hoefer, Klemens, Buckley, Suzanne M K, Mattar, Citra N, Cheng, Seng H, Chan, Jerry K Y, Cooper, Jonathan D, Waddington, Simon N
Published in The FASEB journal (01.10.2011)
Published in The FASEB journal (01.10.2011)
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Fetal gene therapy for neurodegenerative disease of infants
Massaro, Giulia, Mattar, Citra N Z, Wong, Andrew M S, Sirka, Ernestas, Buckley, Suzanne M K, Herbert, Bronwen R, Karlsson, Stefan, Perocheau, Dany P, Burke, Derek, Heales, Simon, Richard-Londt, Angela, Brandner, Sebastian, Huebecker, Mylene, Priestman, David A, Platt, Frances M, Mills, Kevin, Biswas, Arijit, Cooper, Jonathan D, Chan, Jerry K Y, Cheng, Seng H, Waddington, Simon N, Rahim, Ahad A
Published in Nature medicine (01.09.2018)
Published in Nature medicine (01.09.2018)
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An anti-neuroinflammatory that targets dysregulated glia enhances the efficacy of CNS-directed gene therapy in murine infantile neuronal ceroid lipofuscinosis
Macauley, Shannon L, Wong, Andrew M S, Shyng, Charles, Augner, David P, Dearborn, Joshua T, Pearse, Yewande, Roberts, Marie S, Fowler, Stephen C, Cooper, Jonathan D, Watterson, D Martin, Sands, Mark S
Published in The Journal of neuroscience (24.09.2014)
Published in The Journal of neuroscience (24.09.2014)
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Non-invasive molecular imaging of inflammatory macrophages in allograft rejection
O’Neill, Alexander S. G., Terry, Samantha Y. A., Brown, Kathryn, Meader, Lucy, Wong, Andrew M. S., Cooper, Jonathan D., Crocker, Paul R., Wong, Wilson, Mullen, Gregory E. D.
Published in EJNMMI research (01.12.2015)
Published in EJNMMI research (01.12.2015)
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Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late‐gestation nonhuman primates
Mattar, Citra N., Wong, Andrew M. S., Hoefer, Klemens, Alonso‐Ferrero, Maria E., Buckley, Suzanne M. K., Howe, Steven J., Cooper, Jonathan D., Waddington, Simon N., Chan, Jerry K. Y., Rahim, Ahad A.
Published in The FASEB journal (01.09.2015)
Published in The FASEB journal (01.09.2015)
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DHHC5 Interacts with PDZ Domain 3 of Post-synaptic Density-95 (PSD-95) Protein and Plays a Role in Learning and Memory
Li, Yi, Hu, Jie, Höfer, Klemens, Wong, Andrew M.S., Cooper, Jonathan D., Birnbaum, Shari G., Hammer, Robert E., Hofmann, Sandra L.
Published in The Journal of biological chemistry (23.04.2010)
Published in The Journal of biological chemistry (23.04.2010)
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Intravenous high-dose enzyme replacement therapy with recombinant palmitoyl–protein thioesterase reduces visceral lysosomal storage and modestly prolongs survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis
Hu, Jie, Lu, Jui-Yun, Wong, Andrew M.S., Hynan, Linda S., Birnbaum, Shari G., Yilmaz, Denis S., Streit, Barbara M., Lenartowicz, Ewelina M., Thompson, Thomas C.M., Cooper, Jonathan D., Hofmann, Sandra L.
Published in Molecular genetics and metabolism (01.09.2012)
Published in Molecular genetics and metabolism (01.09.2012)
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Behavioral deficits, early gliosis, dysmyelination and synaptic dysfunction in a mouse model of mucolipidosis IV
Grishchuk, Yulia, Sri, Sarmi, Rudinskiy, Nikita, Ma, Weiyuan, Stember, Katherine G, Cottle, Matthew W, Sapp, Ellen, Difiglia, Marian, Muzikansky, Alona, Betensky, Rebecca A, Wong, Andrew M S, Bacskai, Brian J, Hyman, Bradley T, Kelleher, 3rd, Raymond J, Cooper, Jonathan D, Slaugenhaupt, Susan A
Published in Acta neuropathologica communications (09.09.2014)
Published in Acta neuropathologica communications (09.09.2014)
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Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo
Llavero Hurtado, Maica, Fuller, Heidi R, Wong, Andrew M S, Eaton, Samantha L, Gillingwater, Thomas H, Pennetta, Giuseppa, Cooper, Jonathan D, Wishart, Thomas M
Published in Scientific reports (29.09.2017)
Published in Scientific reports (29.09.2017)
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A novel, long-lived, and highly engraftable immunodeficient mouse model of mucopolysaccharidosis type I
Mendez, Daniel C, Stover, Alexander E, Rangel, Anthony D, Brick, David J, Nethercott, Hubert E, Torres, Marissa A, Khalid, Omar, Wong, Andrew Ms, Cooper, Jonathan D, Jester, James V, Monuki, Edwin S, McGuire, Cian, Le, Steven Q, Kan, Shih-Hsin, Dickson, Patricia I, Schwartz, Philip H
Published in Molecular therapy. Methods & clinical development (01.01.2015)
Published in Molecular therapy. Methods & clinical development (01.01.2015)
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Nonclinical evaluation of CNS-administered TPP1 enzyme replacement in canine CLN2 neuronal ceroid lipofuscinosis
Vuillemenot, Brian R., Kennedy, Derek, Cooper, Jonathan D., Wong, Andrew M.S., Sri, Sarmi, Doeleman, Thom, Katz, Martin L., Coates, Joan R., Johnson, Gayle C., Reed, Randall P., Adams, Eric L., Butt, Mark T., Musson, Donald G., Henshaw, Joshua, Keve, Steve, Cahayag, Rhea, Tsuruda, Laurie S., O'Neill, Charles A.
Published in Molecular genetics and metabolism (01.02.2015)
Published in Molecular genetics and metabolism (01.02.2015)
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Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors
Karda, Rajvinder, Rahim, Ahad A, Wong, Andrew M S, Suff, Natalie, Diaz, Juan Antinao, Perocheau, Dany P, Tijani, Maha, Ng, Joanne, Baruteau, Julien, Martin, Nuria Palomar, Hughes, Michael, Delhove, Juliette M K M, Counsell, John R, Cooper, Jonathan D, Henckaerts, Els, Mckay, Tristan R, Buckley, Suzanne M K, Waddington, Simon N
Published in Scientific reports (07.02.2020)
Published in Scientific reports (07.02.2020)
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Immunosuppression alters disease severity in juvenile Batten disease mice
Seehafer, Sabrina S, Ramirez-Montealegre, Denia, Wong, Andrew MS, Chan, Chun-Hung, Castaneda, Julian, Horak, Michael, Ahmadi, Sarah M, Lim, Ming J, Cooper, Jonathan D, Pearce, David A
Published in Journal of neuroimmunology (01.01.2011)
Published in Journal of neuroimmunology (01.01.2011)
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In utero gene transfer to the mouse nervous system
Rahim, Ahad A, Wong, Andrew M S, Buckley, Suzanne M K, Chan, Jerry K Y, David, Anna L, Cooper, Jonathan D, Coutelle, Charles, Peebles, Donald M, Waddington, Simon N
Published in Biochemical Society transactions (01.12.2010)
Published in Biochemical Society transactions (01.12.2010)
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Partial correction of the CNS lysosomal storage defect in a mouse model of juvenile neuronal ceroid lipofuscinosis by neonatal CNS administration of an adeno-associated virus serotype rh.10 vector expressing the human CLN3 gene
Sondhi, Dolan, Scott, Emma C, Chen, Alvin, Hackett, Neil R, Wong, Andrew M S, Kubiak, Agnieszka, Nelvagal, Hemanth R, Pearse, Yewande, Cotman, Susan L, Cooper, Jonathan D, Crystal, Ronald G
Published in Human gene therapy (01.03.2014)
Published in Human gene therapy (01.03.2014)
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The effect of biceps reattachment site
Schmidt, Christopher C., MD, Weir, David M., MS, Wong, Andrew S., MD, Howard, Michael, MD, Miller, Mark Carl, PhD
Published in Journal of shoulder and elbow surgery (01.12.2010)
Published in Journal of shoulder and elbow surgery (01.12.2010)
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