Intermittent Versus Continuous PEG-Asparaginase to Reduce Asparaginase-Associated Toxicities: A NOPHO ALL2008 Randomized Study
Albertsen, Birgitte Klug, Grell, Kathrine, Abrahamsson, Jonas, Lund, Bendik, Vettenranta, Kim, Jónsson, Ólafur G, Frandsen, Thomas L, Wolthers, Benjamin O, Heyman, Mats, Schmiegelow, Kjeld
Published in Journal of clinical oncology (01.07.2019)
Published in Journal of clinical oncology (01.07.2019)
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Relapse risk following truncation of pegylated asparaginase in childhood acute lymphoblastic leukemia
Gottschalk Højfeldt, Sofie, Grell, Kathrine, Abrahamsson, Jonas, Lund, Bendik, Vettenranta, Kim, Jónsson, Ólafur G., Frandsen, Thomas L., Wolthers, Benjamin O., Marquart, Hanne Vibeke, Vaitkeviciene, Goda, Lepik, Kristi, Heyman, Mats, Schmiegelow, Kjeld, Albertsen, Birgitte Klug
Published in Blood (29.04.2021)
Published in Blood (29.04.2021)
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Trypsin-encoding PRSS1-PRSS2 variations influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report
Wolthers, Benjamin O, Frandsen, Thomas L, Patel, Chirag J, Abaji, Rachid, Attarbaschi, Andishe, Barzilai, Shlomit, Colombini, Antonella, Escherich, Gabriele, Grosjean, Marie, Krajinovic, Maja, Larsen, Eric, Liang, Der-Cherng, Möricke, Anja, Rasmussen, Kirsten K, Samarasinghe, Sujith, Silverman, Lewis B, van der Sluis, Inge M, Stanulla, Martin, Tulstrup, Morten, Yadav, Rachita, Yang, Wenjian, Zapotocka, Ester, Gupta, Ramneek, Schmiegelow, Kjeld
Published in Haematologica (Roma) (01.03.2019)
Published in Haematologica (Roma) (01.03.2019)
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Validation of distinct type 2 diabetes clusters and their association with diabetes complications in the DEVOTE, LEADER and SUSTAIN‐6 cardiovascular outcomes trials
Kahkoska, Anna R., Geybels, Milan S., Klein, Klara R., Kreiner, Frederik F., Marx, Nikolaus, Nauck, Michael A., Pratley, Richard E., Wolthers, Benjamin O., Buse, John B.
Published in Diabetes, obesity & metabolism (01.09.2020)
Published in Diabetes, obesity & metabolism (01.09.2020)
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Journal Article
Asparaginase-associated pancreatitis in childhood acute lymphoblastic leukaemia: an observational Ponte di Legno Toxicity Working Group study
Wolthers, Benjamin O, Frandsen, Thomas L, Baruchel, André, Attarbaschi, Andishe, Barzilai, Shlomit, Colombini, Antonella, Escherich, Gabriele, Grell, Kathrine, Inaba, Hiroto, Kovacs, Gábor, Liang, Der-Cherng, Mateos, Marion, Mondelaers, Veerle, Möricke, Anja, Ociepa, Tomasz, Samarasinghe, Sujith, Silverman, Lewis B, van der Sluis, Inge M, Stanulla, Martin, Vrooman, Lynda M, Yano, Michihiro, Zapotocka, Ester, Schmiegelow, Kjeld
Published in The lancet oncology (01.09.2017)
Published in The lancet oncology (01.09.2017)
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Genetic predisposition to PEG‐asparaginase hypersensitivity in children treated according to NOPHO ALL2008
Højfeldt, Sofie G., Wolthers, Benjamin O., Tulstrup, Morten, Abrahamsson, Jonas, Gupta, Ramneek, Harila‐Saari, Arja, Heyman, Mats, Henriksen, Louise T., Jónsson, Òlafur G., Lähteenmäki, Päivi M., Lund, Bendik, Pruunsild, Kaie, Vaitkeviciene, Goda, Schmiegelow, Kjeld, Albertsen, Birgitte K.
Published in British journal of haematology (01.02.2019)
Published in British journal of haematology (01.02.2019)
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Journal Article
Pancreatitis-associated protein as an early marker of asparaginase-associated pancreatitis
Lukes, Julius, Wolthers, Benjamin O., Altaf Raja, Raheel, Uhrinova, Karolina, Skvarova Kramarzova, Karolina, Hermanova, Ivana, Simcikova, Marketa, Kicko, Peter, Zaliova, Marketa, Sramkova, Lucie, Stary, Jan, Trka, Jan, Schmiegelow, Kjeld, Starkova, Julia
Published in Leukemia & lymphoma (06.12.2021)
Published in Leukemia & lymphoma (06.12.2021)
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Can Machine Learning Models Predict Asparaginase-associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia
Nielsen, Rikke L, Wolthers, Benjamin O, Helenius, Marianne, Albertsen, Birgitte K, Clemmensen, Line, Nielsen, Kasper, Kanerva, Jukka, Niinimäki, Riitta, Frandsen, Thomas L, Attarbaschi, Andishe, Barzilai, Shlomit, Colombini, Antonella, Escherich, Gabriele, Aytan-Aktug, Derya, Liu, Hsi-Che, Möricke, Anja, Samarasinghe, Sujith, van der Sluis, Inge M, Stanulla, Martin, Tulstrup, Morten, Yadav, Rachita, Zapotocka, Ester, Schmiegelow, Kjeld, Gupta, Ramneek
Published in Journal of pediatric hematology/oncology (01.04.2022)
Published in Journal of pediatric hematology/oncology (01.04.2022)
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Impact of acute lymphoblastic leukemia induction therapy: findings from metabolomics on non-fasted plasma samples from a biorepository
Saito, Toshie, Wei, Yue, Wen, Li, Srinivasan, Chaitanya, Wolthers, Benjamin O., Tsai, Cheng-Yu, Harris, Marian H., Stevenson, Kristen, Byersdorfer, Craig, Oparaji, Judy-April, Fernandez, Christian, Mukherjee, Amitava, Abu-El-Haija, Maisam, Agnihotri, Sameer, Schmiegelow, Kjeld, Showalter, Megan R., Fogle, Paul W., McCulloch, Scott, Contrepois, Kevin, Silverman, Lewis B., Ding, Ying, Husain, Sohail Z.
Published in Metabolomics (01.07.2021)
Published in Metabolomics (01.07.2021)
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Asparaginase enzyme activity levels and toxicity in childhood acute lymphoblastic leukemia: a NOPHO ALL2008 study
Lynggaard, Line Stensig, Rank, Cecilie Utke, Hansen, Stefan Nygaard, Gottschalk Højfeldt, Sofie, Henriksen, Louise Tram, Jarvis, Kirsten Brunsvig, Ranta, Susanna, Niinimäki, Riitta, Harila-Saari, Arja, Wolthers, Benjamin O, Frandsen, Thomas L., Heyman, Mats, Schmiegelow, Kjeld, Albertsen, Birgitte Klug
Published in Blood advances (11.01.2022)
Published in Blood advances (11.01.2022)
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Genome-Wide Association Meta-Analysis of Single-Nucleotide Polymorphisms and Symptomatic Venous Thromboembolism during Therapy for Acute Lymphoblastic Leukemia and Lymphoma in Caucasian Children
Mateos, Marion K, Tulstrup, Morten, Quinn, Michael Cj, Tuckuviene, Ruta, Marshall, Glenn M, Gupta, Ramneek, Mayoh, Chelsea, Wolthers, Benjamin O, Barbaro, Pasquale M, Ruud, Ellen, Sutton, Rosemary, Huttunen, Pasi, Revesz, Tamas, Trakymiene, Sonata S, Barbaric, Draga, Tedgård, Ulf, Giles, Jodie E, Alvaro, Frank, Jonsson, Olafur G, Mechinaud, Françoise, Saks, Kadri, Catchpoole, Daniel, Kotecha, Rishi S, Dalla-Pozza, Luciano, Chenevix-Trench, Georgia, Trahair, Toby N, MacGregor, Stuart, Schmiegelow, Kjeld
Published in Cancers (19.05.2020)
Published in Cancers (19.05.2020)
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Asparaginase-Associated Pancreatitis in Acute Lymphoblastic Leukemia: Results From the NOPHO ALL2008 Treatment of Patients 1-45 Years of Age
Rank, Cecilie U, Wolthers, Benjamin O, Grell, Kathrine, Albertsen, Birgitte K, Frandsen, Thomas L, Overgaard, Ulrik M, Toft, Nina, Nielsen, Ove J, Wehner, Peder S, Harila-Saari, Arja, Heyman, Mats M, Malmros, Johan, Abrahamsson, Jonas, Norén-Nyström, Ulrika, Tomaszewska-Toporska, Beata, Lund, Bendik, Jarvis, Kirsten B, Quist-Paulsen, Petter, Vaitkevičienė, Goda E, Griškevičius, Laimonas, Taskinen, Mervi, Wartiovaara-Kautto, Ulla, Lepik, Kristi, Punab, Mari, Jónsson, Ólafur G, Schmiegelow, Kjeld
Published in Journal of clinical oncology (2020)
Published in Journal of clinical oncology (2020)
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Journal Article
Genetic predisposition to PEG ‐asparaginase hypersensitivity in children treated according to NOPHO ALL 2008
Højfeldt, Sofie G., Wolthers, Benjamin O., Tulstrup, Morten, Abrahamsson, Jonas, Gupta, Ramneek, Harila‐Saari, Arja, Heyman, Mats, Henriksen, Louise T., Jónsson, Òlafur G., Lähteenmäki, Päivi M., Lund, Bendik, Pruunsild, Kaie, Vaitkeviciene, Goda, Schmiegelow, Kjeld, Albertsen, Birgitte K.
Published in British journal of haematology (01.02.2019)
Published in British journal of haematology (01.02.2019)
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521 - Zuma-25: A Phase 2 Study of Brexucabtagene Autoleucel (KTE-X19) Chimeric Antigen Receptor T-Cell Therapy in Adult Patients with Relapsed/Refractory Rare B-Cell Malignancies
Eichhorst, Barbara, Dunleavy, Kieron, Tiacci, Enrico, Buske, Christian, Jain, Nitin, Castillo, Jorge J., Rossi, Davide, Woolven, Kate, Masouleh, Behzad Kharabi, Peng, Weimin, Schuberth, Petra C., Domper, Neus, Wolthers, Benjamin O., Palomba, M. Lia
Published in Transplantation and cellular therapy (01.02.2023)
Published in Transplantation and cellular therapy (01.02.2023)
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Journal Article
Zuma-25: A Phase 2 Study of Brexucabtagene Autoleucel (KTE-X19) Chimeric Antigen Receptor T-Cell Therapy in Adult Patients with Relapsed/Refractory Rare B-Cell Malignancies
Eichhorst, Barbara, Dunleavy, Kieron, Tiacci, Enrico, Buske, Christian, Jain, Nitin, Castillo, Jorge J., Rossi, Davide, Woolven, Kate, Masouleh, Behzad Kharabi, Peng, Weimin, Schuberth, Petra C., Domper, Neus, Wolthers, Benjamin O., Palomba, M. Lia
Published in Transplantation and cellular therapy (01.02.2023)
Published in Transplantation and cellular therapy (01.02.2023)
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