Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA₁c levels in human pancreatic islets
Yang, B. T, Dayeh, T. A, Kirkpatrick, C. L, Taneera, J, Kumar, R, Groop, L, Wollheim, C. B, Nitert, M. D, Ling, C
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Published in Diabetologia (01.02.2011)
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Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress
Xu, S, Nam, S M, Kim, J-H, Das, R, Choi, S-K, Nguyen, T T, Quan, X, Choi, S J, Chung, C H, Lee, E Y, Lee, I-K, Wiederkehr, A, Wollheim, C B, Cha, S-K, Park, K-S
Published in Cell death & disease (19.11.2015)
Published in Cell death & disease (19.11.2015)
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A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets
Marchetti, P., Lupi, R., Bugliani, M., Kirkpatrick, C. L., Sebastiani, G., Grieco, F. A., Del Guerra, S., D’Aleo, V., Piro, S., Marselli, L., Boggi, U., Filipponi, F., Tinti, L., Salvini, L., Wollheim, C. B., Purrello, F., Dotta, F.
Published in Diabetologia (01.12.2012)
Published in Diabetologia (01.12.2012)
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Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes
Axelsson, A. S., Mahdi, T., Nenonen, H. A., Singh, T., Hänzelmann, S., Wendt, A., Bagge, A., Reinbothe, T. M., Millstein, J., Yang, X., Zhang, B., Gusmao, E. G., Shu, L., Szabat, M., Tang, Y., Wang, J., Salö, S., Eliasson, L., Artner, I., Fex, M., Johnson, J. D., Wollheim, C. B., Derry, J.M.J., Mecham, B., Spégel, P., Mulder, H., Costa, I.G., Zhang, E., Rosengren, A. H.
Published in Nature communications (06.06.2017)
Published in Nature communications (06.06.2017)
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Increased uptake of oxLDL does not exert lipotoxic effects in insulin-secreting cells
Ma, Z, Ketelhuth, D F J, Wirström, T, Ohki, T, Forteza, M J, Wang, H, Grill, V, Wollheim, C B, Björklund, A
Published in Journal of molecular endocrinology (01.05.2019)
Published in Journal of molecular endocrinology (01.05.2019)
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A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets
MARCHETTI, P, LUPI, R, BOGGI, U, FILIPPONI, F, TINTI, L, SALVINI, L, WOLLHEIM, C. B, PURRELLO, F, DOTTA, F, BUGLIANI, M, KIRKPATRICK, C. L, SEBASTIANI, G, GRIECO, F. A, DEL GUERRA, S, D'ALEO, V, PIRO, S, MARSELLI, L
Published in Diabetologia (01.12.2012)
Published in Diabetologia (01.12.2012)
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Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes
Shcherbina, L., Edlund, A., Esguerra, J.L.S., Abels, M., Zhou, Y., Ottosson-Laakso, E., Wollheim, C.B., Hansson, O., Eliasson, L., Wierup, N.
Published in Molecular and cellular endocrinology (15.05.2017)
Published in Molecular and cellular endocrinology (15.05.2017)
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Amiloride derivatives induce apoptosis by depleting ER Ca2+ stores in vascular endothelial cells
Park, KS, Poburko, D, Wollheim, CB, Demaurex, N
Published in British journal of pharmacology (01.04.2009)
Published in British journal of pharmacology (01.04.2009)
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Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species
PRODUIT-ZENGAFFINEN, N, DAVIS -LAMELOISE, N, PERRETEN, H, BECARD, D, GJINOVCI, A, KELLER, P. A, WOLLHEIM, C. B, HERRERA, P, MUZZIN, P, ASSIMACOPOULOS-JEANNET, F
Published in Diabetologia (01.01.2007)
Published in Diabetologia (01.01.2007)
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Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells
WANG, H, IEZZI, M, THEANDER, S, ANTINOZZI, P. A, GAUTHIER, B. R, HALBAN, P. A, WOLLHEIM, C. B
Published in Diabetologia (01.04.2005)
Published in Diabetologia (01.04.2005)
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Reduced insulin secretion and content in VEGF-a deficient mouse pancreatic islets
Jabs, N, Franklin, I, Brenner, M B, Gromada, J, Ferrara, N, Wollheim, C B, Lammert, E
Published in Experimental and clinical endocrinology & diabetes (01.09.2008)
Published in Experimental and clinical endocrinology & diabetes (01.09.2008)
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Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells
Park, K S, Poburko, D, Wollheim, C B, Demaurex, N
Published in British journal of pharmacology (01.04.2009)
Published in British journal of pharmacology (01.04.2009)
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The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells
BRUN, T, DUHAMEL, D. L, HU HE, K. H, WOLLHEIM, C. B, GAUTHIER, B. R
Published in Oncogene (21.06.2007)
Published in Oncogene (21.06.2007)
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Hepatocyte Nuclear Factor 4α Regulates the Expression of Pancreatic β-Cell Genes Implicated in Glucose Metabolism and Nutrient-induced Insulin Secretion
Wang, Haiyan, Maechler, Pierre, Antinozzi, Peter A., Hagenfeldt, Kerstin A., Wollheim, Claes B.
Published in The Journal of biological chemistry (17.11.2000)
Published in The Journal of biological chemistry (17.11.2000)
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