Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia
Layton, Mark E., Kern, Jeffrey C., Hartingh, Timothy J., Shipe, William D., Raheem, Izzat, Kandebo, Monika, Hayes, Robert P., Huszar, Sarah, Eddins, Donnie, Ma, Bennett, Fuerst, Joy, Wollenberg, Gordon K., Li, Jing, Fritzen, Jeff, McGaughey, Georgia B., Uslaner, Jason M., Smith, Sean M., Coleman, Paul J., Cox, Christopher D.
Published in Journal of medicinal chemistry (26.01.2023)
Published in Journal of medicinal chemistry (26.01.2023)
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Invention of MK-8262, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor Backup to Anacetrapib with Best-in-Class Properties
Vachal, Petr, Duffy, Joseph L, Campeau, Louis-Charles, Amin, Rupesh P, Mitra, Kaushik, Murphy, Beth Ann, Shao, Pengcheng P, Sinclair, Peter J, Ye, Feng, Katipally, Revathi, Lu, Zhijian, Ondeyka, Debra, Chen, Yi-Heng, Zhao, Kake, Sun, Wanying, Tyagarajan, Sriram, Bao, Jianming, Wang, Sheng-Ping, Cote, Josee, Lipardi, Concetta, Metzger, Daniel, Leung, Dennis, Hartmann, Georgy, Wollenberg, Gordon K, Liu, Jian, Tan, Lushi, Xu, Yingju, Chen, Qinghao, Liu, Guiquan, Blaustein, Robert O, Johns, Douglas G
Published in Journal of medicinal chemistry (23.09.2021)
Published in Journal of medicinal chemistry (23.09.2021)
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Journal Article
Role of chronic toxicology studies in revealing new toxicities
Galijatovic-Idrizbegovic, Alema, Miller, Judith E., Cornell, Wendy D., Butler, James A., Wollenberg, Gordon K., Sistare, Frank D., DeGeorge, Joseph J.
Published in Regulatory toxicology and pharmacology (01.12.2016)
Published in Regulatory toxicology and pharmacology (01.12.2016)
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Journal Article
Recombinant Rat and Mouse Growth Hormones: Risk Assessment of Carcinogenic Potential in 2-Year Bioassays in Rats and Mice
Farris, Georgia M., Miller, Glen K., Wollenberg, Gordon K., Molon-Noblot, Sylvain, Chan, Christine, Prahalada, Srinivasa
Published in Toxicological sciences (01.06.2007)
Published in Toxicological sciences (01.06.2007)
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Journal Article
Differential local and systemic regulation of the murine chemokines KC and MIP2
Call, D R, Nemzek, J A, Ebong, S J, Bolgos, G R, Newcomb, D E, Wollenberg, G K, Remick, D G
Published in Shock (Augusta, Ga.) (01.04.2001)
Published in Shock (Augusta, Ga.) (01.04.2001)
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Tumor necrosis factor α is not required for WY14,643-induced cell proliferation
Lawrence, Jeffrey W., Wollenberg, Gordon K., DeLuca, John G.
Published in Carcinogenesis (New York) (01.03.2001)
Published in Carcinogenesis (New York) (01.03.2001)
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Journal Article
Effects of LRRK2 Inhibitors in Nonhuman Primates
Miller, Glen K, Kuruvilla, Sabu, Jacob, Binod, LaFranco-Scheuch, Lisa, Bakthavatchalu, Vasudevan, Flor, Jason, Flor, Kristin, Ziegler, Julie, Reichard, Christine, Manfre, Phil, Firner, Suzanne, McNutt, Tara, Quay, Diane, Bellum, Sairam, Doto, Greg, Ciaccio, Paul J, Pearson, Kara, Valentine, Jack, Fuller, Pete, Fell, Matt, Tsuchiya, Takayuki, Williamson, Toni, Wollenberg, Gordon
Published in Toxicologic pathology (01.07.2023)
Published in Toxicologic pathology (01.07.2023)
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Journal Article
Early-Onset albuminuria and Associated Renal Pathology in Leucine-Rich Repeat Kinase 2 Knockout Rats
Gu, Yi-Zhong, Vlasakova, Katerina, Miller, Glen, Gatto, Nicholas T, Ciaccio, Paul J, Kuruvilla, Sabu, Besteman, Elizabeth G, Smith, Roger, Reynolds, Spencer J, Amin, Rupesh P, Glaab, Warren E, Wollenberg, Gordon, Lebron, Jose, Sistare, Frank D
Published in Toxicologic pathology (01.01.2023)
Published in Toxicologic pathology (01.01.2023)
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Journal Article
Lead Optimization to Advance Protease-Activated Receptor‑1 Antagonists in Early Discovery
Mandal, Mihirbaran, Madeira, Maria, Amin, Rupesh P, Buevich, Alexei V, Cheng, Alan, Labroli, Marc, Liu, Xiaoxiang, Acton, John, Pio, Barbara, Basso, Andrea, Chobanian, Harry, Dong, Grace, Dropinski, Jamie, Guo, Yan, Guo, Zhuyan, Kurowski, Stan, Korfmacher, Walter, Lee, Sandra, Meng, Dongfang, Ondeyka, Debra, Yang, Zhiqiang, Zhang, Rumin, Wei, Huijun, Wu, Zhicai, Zhang, Fengqi, Wollenberg, Gordon, Biftu, Tesfaye, Greenlee, William J, Chintala, Madhu, Maletic, Milana, Zhu, Zhaoning
Published in Journal of medicinal chemistry (14.04.2022)
Published in Journal of medicinal chemistry (14.04.2022)
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Cardiac drug-drug interaction between HCV-NS5B pronucleotide inhibitors and amiodarone is determined by their specific diastereochemistry
Lagrutta, Armando, Regan, Christopher P, Zeng, Haoyu, Imredy, John P, Koeplinger, Kenneth, Morissette, Pierre, Liu, Liping, Wollenberg, Gordon, Brynczka, Christopher, Lebrón, José, DeGeorge, Joseph, Sannajust, Frederick
Published in Scientific reports (22.03.2017)
Published in Scientific reports (22.03.2017)
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Journal Article
Peliosis hepatis in a dog infected with Bartonella henselae
Kitchell, B E, Fan, T M, Kordick, D, Breitschwerdt, E B, Wollenberg, G, Lichtensteiger, C A
Published in Journal of the American Veterinary Medical Association (15.02.2000)
Published in Journal of the American Veterinary Medical Association (15.02.2000)
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Journal Article
Prolonged Sublethal Exposure to the Protein Phosphatase Inhibitor Microcystin-LR Results in Multiple Dose-Dependent Hepatotoxic Effects
Solter, Philip F., Wollenberg, Gordon K., Huang, Xuan, Chu, Fun S., Runnegar, Maria T.
Published in Toxicological sciences (01.07.1998)
Published in Toxicological sciences (01.07.1998)
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Journal Article
Exogenous interleukin-10 fails to decrease the mortality or morbidity of sepsis
Remick, D G, Garg, S J, Newcomb, D E, Wollenberg, G, Huie, T K, Bolgos, G L
Published in Critical care medicine (01.05.1998)
Published in Critical care medicine (01.05.1998)
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Journal Article
Human tumor necrosis factor receptor (p55) and interleukin 10 gene transfer in the mouse reduces mortality to lethal endotoxemia and also attenuates local inflammatory responses
Rogy, M A, Auffenberg, T, Espat, N J, Philip, R, Remick, D, Wollenberg, G K, Copeland, 3rd, E M, Moldawer, L L
Published in The Journal of experimental medicine (01.06.1995)
Published in The Journal of experimental medicine (01.06.1995)
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Journal Article
Binding of tumor necrosis factor alpha to activated forms of human plasma alpha2 macroglobulin
WOLLENBERG, G. K, LAMARRE, J, ROSENDAL, S, GONIAS, S. L, HAYES, M. A
Published in The American journal of pathology (01.02.1991)
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Published in The American journal of pathology (01.02.1991)
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