Tofacitinib, an oral Janus kinase inhibitor, for the treatment of chronic plaque psoriasis: results from two randomized, placebo-controlled, phase III trials
Papp, K.A., Menter, M.A., Abe, M., Elewski, B., Feldman, S.R., Gottlieb, A.B., Langley, R., Luger, T., Thaci, D., Buonanno, M., Gupta, P., Proulx, J., Lan, S., Wolk, R.
Published in British journal of dermatology (1951) (01.10.2015)
Published in British journal of dermatology (1951) (01.10.2015)
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Efficacy and safety of tofacitinib, an oral Janus kinase inhibitor, in the treatment of psoriasis: a Phase 2b randomized placebo-controlled dose-ranging study
Papp, K.A., Menter, A., Strober, B., Langley, R.G., Buonanno, M., Wolk, R., Gupta, P., Krishnaswami, S., Tan, H., Harness, J.A.
Published in British journal of dermatology (1951) (01.09.2012)
Published in British journal of dermatology (1951) (01.09.2012)
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Tofacitinib withdrawal and retreatment in moderate-to-severe chronic plaque psoriasis: a randomized controlled trial
Bissonnette, R., Iversen, L., Sofen, H., Griffiths, C.E.M., Foley, P., Romiti, R., Bachinsky, M., Rottinghaus, S.T., Tan, H., Proulx, J., Valdez, H., Gupta, P., Mallbris, L., Wolk, R.
Published in British journal of dermatology (1951) (01.05.2015)
Published in British journal of dermatology (1951) (01.05.2015)
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Journal Article
Effect of tofacitinib, a Janus kinase inhibitor, on haematological parameters during 12 weeks of psoriasis treatment
Strober, B., Buonanno, M., Clark, J.D., Kawabata, T., Tan, H., Wolk, R., Valdez, H., Langley, R.G., Harness, J., Menter, A., Papp, K.
Published in British journal of dermatology (1951) (01.11.2013)
Published in British journal of dermatology (1951) (01.11.2013)
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Journal Article
Benefit–risk profile of tofacitinib in patients with moderate‐to‐severe chronic plaque psoriasis: pooled analysis across six clinical trials
Strober, B.E., Gottlieb, A.B., Kerkhof, P.C.M., Puig, L., Bachelez, H., Chouela, E., Imafuku, S., Thaçi, D., Tan, H., Valdez, H., Gupta, P., Kaur, M., Frajzyngier, V., Wolk, R.
Published in British journal of dermatology (1951) (01.01.2019)
Published in British journal of dermatology (1951) (01.01.2019)
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Journal Article
Quantitative Evaluations of Time‐Course and Treatment Effects of Systemic Agents for Psoriasis: A Model‐Based Meta‐Analysis
Checchio, T, Ahadieh, S, Gupta, P, Mandema, J, Puig, L, Wolk, R, Valdez, H, Tan, H, Krishnaswami, S, Tallman, A, Kaur, M, Ito, K
Published in Clinical pharmacology and therapeutics (01.12.2017)
Published in Clinical pharmacology and therapeutics (01.12.2017)
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Association between serum interleukin‐17A and clinical response to tofacitinib and etanercept in moderate to severe psoriasis
Fitz, L., Zhang, W., Soderstrom, C., Fraser, S., Lee, J., Quazi, A., Wolk, R., Mebus, C. A., Valdez, H., Berstein, G.
Published in Clinical and experimental dermatology (01.10.2018)
Published in Clinical and experimental dermatology (01.10.2018)
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Journal Article
Tofacitinib benefit‐risk profile in chronic plaque psoriasis
Strober, B.E., Gottlieb, A.B., Kerkhof, P.C.M., Puig, L., Bachelez, H., Chouela, E., Imafuku, S., Thaçi, D., Tan, H., Valdez, H., Gupta, P., Kaur, M., Frajzyngier, V., Wolk, R.
Published in British journal of dermatology (1951) (01.01.2019)
Published in British journal of dermatology (1951) (01.01.2019)
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Journal Article
THU0299 An integrated analysis of changes in lipid levels and incidence of cardiovascular events following tofacitinib treatment in patients with psoriatic arthritis across phase 3 and long-term extension studies
Gladman, D.D., Charles-Schoeman, C., McInnes, I.B., Veale, D.J., Thiers, B., Graham, D., Wang, C., Jones, T.V., Wolk, R., DeMasi, R.
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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Association between plasma adiponectin levels and unstable coronary syndromes
Wolk, Robert, Berger, Peter, Lennon, Ryan J., Brilakis, Emmanouil S., Davison, Diane E., Somers, Virend K.
Published in European heart journal (01.02.2007)
Published in European heart journal (01.02.2007)
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Journal Article
THU0187 Safety of Tofacitinib, An Oral Janus Kinase Inhibitor: Integrated Data Analysis from The Global Chronic Plaque Psoriasis Clinical Trials
Langley, R.G.B., Cohen, A.D., Foley, P., Griffiths, C.E.M., Lebwohl, M., Leonardi, C., Winthrop, K., Proulx, J., Rottinghaus, S.T., Wolk, R., Thompson, J.R., Tatulych, S., Mallbris, L., Swanson, R.
Published in Annals of the rheumatic diseases (01.06.2016)
Published in Annals of the rheumatic diseases (01.06.2016)
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Journal Article
Evaluating Dosage Optimality for Tofacitinib, an Oral Janus Kinase Inhibitor, in Plaque Psoriasis, and the Influence of Body Weight
Hutmacher, MM, Papp, K, Krishnaswami, S, Ito, K, Tan, H, Wolk, R, Valdez, H, Mebus, C, Rottinghaus, ST, Gupta, P
Published in CPT: pharmacometrics and systems pharmacology (01.05.2017)
Published in CPT: pharmacometrics and systems pharmacology (01.05.2017)
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Journal Article
Extrasystolic beats affect transmural electrical dispersion during programmed electrical stimulation
Wolk, R., Stec, S., Kulakowski, P.
Published in European journal of clinical investigation (01.04.2001)
Published in European journal of clinical investigation (01.04.2001)
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Journal Article
Leptin receptor and functional effects of leptin in human endothelial progenitor cells
Wolk, Robert, Deb, Arjun, Caplice, Noel M., Somers, Virend K.
Published in Atherosclerosis (01.11.2005)
Published in Atherosclerosis (01.11.2005)
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Journal Article
托法替布在慢性斑块型银屑病中的获益风险特征
Strober, B.E., Gottlieb, A.B., Kerkhof, P.C.M., Puig, L., Bachelez, H., Chouela, E., Imafuku, S., Thaçi, D., Tan, H., Valdez, H., Gupta, P., Kaur, M., Frajzyngier, V., Wolk, R.
Published in British journal of dermatology (1951) (01.01.2019)
Published in British journal of dermatology (1951) (01.01.2019)
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Journal Article
Dose Response and Pharmacokinetics of Tofacitinib (CP‐690,550), an Oral Janus Kinase Inhibitor, in the Treatment of Chronic Plaque Psoriasis
Tan, H, Gupta, P, Harness, J, Wolk, R, Chapel, S, Menter, A, Strober, B, Langley, RG, Krishnaswami, S, Papp, KA
Published in CPT: pharmacometrics and systems pharmacology (01.05.2013)
Published in CPT: pharmacometrics and systems pharmacology (01.05.2013)
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Journal Article
Functional, structural, and dynamic basis of electrical heterogeneity in healthy and diseased cardiac muscle: implications for arrhythmogenesis and anti-arrhythmic drug therapy
Wolk, Robert, Cobbe, Stuart M., Hicks, Martin N., Kane, Kathleen A.
Published in Pharmacology & therapeutics (Oxford) (01.11.1999)
Published in Pharmacology & therapeutics (Oxford) (01.11.1999)
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