Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance
Quanz, Maria, Bender, Eckhard, Kopitz, Charlotte, Grünewald, Sylvia, Schlicker, Andreas, Schwede, Wolfgang, Eheim, Ashley, Toschi, Luisella, Neuhaus, Roland, Richter, Carmen, Toedling, Joern, Merz, Claudia, Lesche, Ralf, Kamburov, Atanas, Siebeneicher, Holger, Bauser, Marcus, Hägebarth, Andrea
Published in Molecular cancer therapeutics (01.11.2018)
Published in Molecular cancer therapeutics (01.11.2018)
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Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies
Möller, Carsten, Bone, Wilhelm, Cleve, Arwed, Klar, Ulrich, Rotgeri, Andrea, Rottmann, Antje, Schultze‐Mosgau, Marcus‐Hillert, Wagenfeld, Andrea, Schwede, Wolfgang
Published in ChemMedChem (06.11.2018)
Published in ChemMedChem (06.11.2018)
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Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179
Mowat, Jeffrey, Ehrmann, Alexander H. M, Christian, Sven, Sperl, Carolyn, Menz, Stephan, Günther, Judith, Hillig, Roman C, Bauser, Marcus, Schwede, Wolfgang
Published in ACS medicinal chemistry letters (10.03.2022)
Published in ACS medicinal chemistry letters (10.03.2022)
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Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development
Klar, Ulrich, Buchmann, Bernd, Schwede, Wolfgang, Skuballa, Werner, Hoffmann, Jens, Lichtner, Rosemarie B.
Published in Angewandte Chemie International Edition (04.12.2006)
Published in Angewandte Chemie International Edition (04.12.2006)
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Synthesis and Biological Activity of a Novel, Highly Potent Progesterone Receptor Antagonist
Fuhrmann, Ulrike, Hess-Stumpp, Holger, Cleve, Arwed, Neef, Günter, Schwede, Wolfgang, Hoffmann, Jens, Fritzemeier, Karl-Heinrich, Chwalisz, Kristof
Published in Journal of medicinal chemistry (28.12.2000)
Published in Journal of medicinal chemistry (28.12.2000)
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Abstract 3248: Identification and optimization of a highly active, cross reactive Complex-1 inhibitor
Mowat, Jeffrey, Christian, Sven, Sperl, Carolyn, Ehrmann, Alexander, Menz, Stephan, Guenther, Judith, Hillig, Roman, Bauser, Marcus, Haegebarth, Andrea, Schwede, Wolfgang
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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7α,15α-Ethano bridged steroids. Synthesis and progesterone receptor interaction
Egner, Ursula, Fritzemeier, Karl-Heinrich, Halfbrodt, Wolfgang, Heinrich, Nikolaus, Kuhnke, Joachim, Müller-Fahrnow, Anke, Neef, Günter, Schöllkopf, Klaus, Schwede, Wolfgang
Published in Tetrahedron (01.09.1999)
Published in Tetrahedron (01.09.1999)
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Abstract 1126: Differential effects of metformin and phenformin vs. other complex 1 inhibitors in vitro and in vivo
Algire, Carolyn, Ehrmann, Alexander, Christian, Sven, Neuhaus, Roland, Menz, Stephan, Schwede, Wolfgang, Haerter, Michael, Haegebarth, Andrea
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Front Cover: Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies (ChemMedChem 21/2018)
Möller, Carsten, Bone, Wilhelm, Cleve, Arwed, Klar, Ulrich, Rotgeri, Andrea, Rottmann, Antje, Schultze‐Mosgau, Marcus‐Hillert, Wagenfeld, Andrea, Schwede, Wolfgang
Published in ChemMedChem (06.11.2018)
Published in ChemMedChem (06.11.2018)
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Abstract 223: Comparison of human-specific versus cross-reactive Complex I inhibitor for in vivo tumor efficacy
Christian, Sven, Algire, Carolyn, Schwede, Wolfgang, Mowat, Jeffrey S., Ehrmann, Alexander, Menz, Stephan, Bauser, Marcus, Haegebarth, Andrea
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 4989: 3D spheroid screen yields SCD1 pathway inhibitors for the treatment of cancer
Gruenewald, Sylvia, Sperl, Carolyn, Steigemann, Patrick, Walter, Alexander, Zacharias, Sylvia, Eberspaecher, Uwe, Neuhaus, Roland, Zorn, Ludwig, Schwede, Wolfgang, Thede, Kai, Christian, Sven
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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BAY 1002670: a novel, highly potent and selective progesterone receptor modulator for gynaecological therapies
Wagenfeld, Andrea, Bone, Wilhelm, Schwede, Wolfgang, Fritsch, Martin, Fischer, Oliver M., Moeller, Carsten
Published in Human reproduction (Oxford) (01.08.2013)
Published in Human reproduction (Oxford) (01.08.2013)
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Abstract 317: 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions
Wenzel, Carsten, Christian, Sven, Algire, Carolyn, Schwede, Wolfgang, Neuhaus, Roland, Guenther, Judith, Liu, Ningshu, Raese, Sebastian, Parczyk, Karsten, Prechtl, Stefan, Steigemann, Patrick
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract 2682: Small molecule targeting the lipoic acid post-translational modification impacts proliferation of colorectal and PIK3CA-mutant cell lines
Doherty, Laura, Sangpo, Tenzin, Tsvetkov, Peter, Davis, John, Dianati, Navid, Schwede, Wolfgang, Zimmermann, Katja, Evans, Laura, Amatucci, Aldo, Seidel, Henrik, Kamburov, Atanas, Akcay, Gizem, Golub, Todd, Eheim, Ashley, Burkhardt, Nils, Eis, Knut, Christian, Sven, Rees, Matt, Roth, Jennifer
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone
HOFFMANN, Jens, VILALE, Ilio, PANARETAKIS, Theocharis, SIEMEISTER, Gerhard, LAGE, Hermann, NANTY, Lisa, HAMMER, Stefanie, MITTELSTAEDT, Kevin, WINSEL, Sebastian, ESCHENBRENNER, Julia, CASTEDO, Maria, DEMARCHE, Carine, BUCHMANN, Bernd, KLAR, Ulrich, KROEMER, Guido, GALLUZZI, Lorenzo, SCHWEDE, Wolfgang, SENOVILLA, Laura, SKUBALLA, Werner, VIVET, Sonia, LICHTNER, Rosemarie B, VICENCIO, José M
Published in Cancer research (Chicago, Ill.) (01.07.2008)
Published in Cancer research (Chicago, Ill.) (01.07.2008)
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Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system
Afhüppe, Wiebke, Sommer, Anette, Müller, Jörg, Schwede, Wolfgang, Fuhrmann, Ulrike, Möller, Carsten
Published in The Journal of steroid biochemistry and molecular biology (2009)
Published in The Journal of steroid biochemistry and molecular biology (2009)
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