Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets
Cox, Robert M., Wolf, Josef D., Lieber, Carolin M., Sourimant, Julien, Lin, Michelle J., Babusis, Darius, DuPont, Venice, Chan, Julie, Barrett, Kim T., Lye, Diane, Kalla, Rao, Chun, Kwon, Mackman, Richard L., Ye, Chengjin, Cihlar, Tomas, Martinez-Sobrido, Luis, Greninger, Alexander L., Bilello, John P., Plemper, Richard K.
Published in Nature communications (05.11.2021)
Published in Nature communications (05.11.2021)
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SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model
Lieber, Carolin M., Cox, Robert M., Sourimant, Julien, Wolf, Josef D., Juergens, Kate, Phung, Quynh, Saindane, Manohar T., Smith, Meghan K., Sticher, Zachary M., Kalykhalov, Alexander A., Natchus, Michael G., Painter, George R., Sakamoto, Kaori, Greninger, Alexander L., Plemper, Richard K.
Published in Nature communications (29.07.2022)
Published in Nature communications (29.07.2022)
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Comparing molnupiravir and nirmatrelvir/ritonavir efficacy and the effects on SARS-CoV-2 transmission in animal models
Cox, Robert M., Lieber, Carolin M., Wolf, Josef D., Karimi, Amirhossein, Lieberman, Nicole A. P., Sticher, Zachary M., Roychoudhury, Pavitra, Andrews, Meghan K., Krueger, Rebecca E., Natchus, Michael G., Painter, George R., Kolykhalov, Alexander A., Greninger, Alexander L., Plemper, Richard K.
Published in Nature communications (07.08.2023)
Published in Nature communications (07.08.2023)
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Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets
Cox, Robert M., Wolf, Josef D., Lieberman, Nicole A., Lieber, Carolin M., Kang, Hae-Ji, Sticher, Zachary M., Yoon, Jeong-Joong, Andrews, Meghan K., Govindarajan, Mugunthan, Krueger, Rebecca E., Sobolik, Elizabeth B., Natchus, Michael G., Gewirtz, Andrew T., deSwart, Rik L., Kolykhalov, Alexander A., Hekmatyar, Khan, Sakamoto, Kaori, Greninger, Alexander L., Plemper, Richard K.
Published in Nature communications (08.02.2024)
Published in Nature communications (08.02.2024)
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The small molecule inhibitor of SARS-CoV-2 3CLpro EDP-235 prevents viral replication and transmission in vivo
Rhodin, Michael H. J., Reyes, Archie C., Balakrishnan, Anand, Bisht, Nalini, Kelly, Nicole M., Gibbons, Joyce Sweeney, Lloyd, Jonathan, Vaine, Michael, Cressey, Tessa, Crepeau, Miranda, Shen, Ruichao, Manalo, Nathan, Castillo, Jonathan, Levene, Rachel E., Leonard, Daniel, Zang, Tianzhu, Jiang, Lijuan, Daniels, Kellye, Cox, Robert M., Lieber, Carolin M., Wolf, Josef D., Plemper, Richard K., Leist, Sarah R., Scobey, Trevor, Baric, Ralph S., Wang, Guoqiang, Goodwin, Bryan, Or, Yat Sun
Published in Nature communications (01.08.2024)
Published in Nature communications (01.08.2024)
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Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding
Wittwer, Kevin, Anderson, Danielle E., Pfeffermann, Kristin, Cox, Robert M., Wolf, Josef D., Santibanez, Sabine, Mankertz, Annette, Plesker, Roland, Sticher, Zachary M., Kolkykhalov, Alexander A., Natchus, Michael G., Pfaller, Christian K., Plemper, Richard K., von Messling, Veronika
Published in Nature communications (02.09.2021)
Published in Nature communications (02.09.2021)
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Teaching transferable skills in teamwork, accountability, goal setting, writing, and problem-solving in a non-major microbiology lab: the unknown bacteria experiment redefined
McKee, Felicia, Wolf, Josef D, Simon, Samantha, Floyd, Jeanetta H
Published in Journal of microbiology & biology education (01.12.2023)
Published in Journal of microbiology & biology education (01.12.2023)
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4'-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication
Sourimant, Julien, Lieber, Carolin M, Aggarwal, Megha, Cox, Robert M, Wolf, Josef D, Yoon, Jeong-Joong, Toots, Mart, Ye, Chengin, Sticher, Zachary, Kolykhalov, Alexander A, Martinez-Sobrido, Luis, Bluemling, Gregory R, Natchus, Michael G, Painter, George R, Plemper, Richard K
Published in Science (American Association for the Advancement of Science) (14.01.2022)
Published in Science (American Association for the Advancement of Science) (14.01.2022)
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SARS-CoV-2 variant of concern type and biological sex affect efficacy of molnupiravir in dwarf hamster model of severe COVID-19
Lieber, Carolin M, Cox, Robert M, Sourimant, Julien, Wolf, Josef D, Juergens, Kate, Phung, Quynh, Saindane, Manohar T, Natchus, Michael G, Painter, George R, Sakamoto, Kaori, Greninger, Alexander L, Plemper, Richard K
Published in bioRxiv (07.02.2022)
Published in bioRxiv (07.02.2022)
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4'-Fluorouridine is a broad-spectrum orally efficacious antiviral blocking respiratory syncytial virus and SARS-CoV-2 replication
Sourimant, Julien, Lieber, Carolin M, Aggarwal, Megha, Cox, Robert M, Wolf, Josef D, Yoon, Jeong-Joong, Toots, Mart, Ye, Chengin, Sticher, Zachary, Kolykhalov, Alexander A, Martinez-Sobrido, Luis, Bluemling, Gregory R, Natchus, Michael G, Painter, George R, Plemper, Richard K
Published in bioRxiv (20.05.2021)
Published in bioRxiv (20.05.2021)
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