METLIN: A Technology Platform for Identifying Knowns and Unknowns
Guijas, Carlos, Montenegro-Burke, J. Rafael, Domingo-Almenara, Xavier, Palermo, Amelia, Warth, Benedikt, Hermann, Gerrit, Koellensperger, Gunda, Huan, Tao, Uritboonthai, Winnie, Aisporna, Aries E, Wolan, Dennis W, Spilker, Mary E, Benton, H. Paul, Siuzdak, Gary
Published in Analytical chemistry (Washington) (06.03.2018)
Published in Analytical chemistry (Washington) (06.03.2018)
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SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
Zheng, Qinheng, Woehl, Jordan L., Kitamura, Seiya, Santos-Martins, Diogo, Smedley, Christopher J., Li, Gencheng, Forli, Stefano, Moses, John E., Wolan, Dennis W., Sharpless, K. Barry
Published in Proceedings of the National Academy of Sciences - PNAS (17.09.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (17.09.2019)
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Journal Article
Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic
Chin, Emily N, Yu, Chenguang, Vartabedian, Vincent F, Jia, Ying, Kumar, Manoj, Gamo, Ana M, Vernier, William, Ali, Sabrina H, Kissai, Mildred, Lazar, Daniel C, Nguyen, Nhan, Pereira, Laura E, Benish, Brent, Woods, Ashley K, Joseph, Sean B, Chu, Alan, Johnson, Kristen A, Sander, Philipp N, Martínez-Peña, Francisco, Hampton, Eric N, Young, Travis S, Wolan, Dennis W, Chatterjee, Arnab K, Schultz, Peter G, Petrassi, H Michael, Teijaro, John R, Lairson, Luke L
Published in Science (American Association for the Advancement of Science) (21.08.2020)
Published in Science (American Association for the Advancement of Science) (21.08.2020)
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Journal Article
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
Smedley, Christopher J., Li, Gencheng, Barrow, Andrew S., Gialelis, Timothy L., Giel, Marie‐Claire, Ottonello, Alessandra, Cheng, Yunfei, Kitamura, Seiya, Wolan, Dennis W., Sharpless, K. Barry, Moses, John E.
Published in Angewandte Chemie International Edition (20.07.2020)
Published in Angewandte Chemie International Edition (20.07.2020)
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Journal Article
Small-Molecule Activators of a Proenzyme
Wolan, Dennis W, Zorn, Julie A, Gray, Daniel C, Wells, James A
Published in Science (American Association for the Advancement of Science) (06.11.2009)
Published in Science (American Association for the Advancement of Science) (06.11.2009)
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Journal Article
Discovery of small-molecule enzyme activators by activity-based protein profiling
Kok, Bernard P, Ghimire, Srijana, Kim, Woojoo, Chatterjee, Shreyosree, Johns, Tyler, Kitamura, Seiya, Eberhardt, Jerome, Ogasawara, Daisuke, Xu, Janice, Sukiasyan, Ara, Kim, Sean M, Godio, Cristina, Bittencourt, Julia M, Cameron, Michael, Galmozzi, Andrea, Forli, Stefano, Wolan, Dennis W, Cravatt, Benjamin F, Boger, Dale L, Saez, Enrique
Published in Nature chemical biology (01.09.2020)
Published in Nature chemical biology (01.09.2020)
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Journal Article
Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions
Yoon, Michael C, Solania, Angelo, Jiang, Zhenze, Christy, Mitchell P, Podvin, Sonia, Mosier, Charles, Lietz, Christopher B, Ito, Gen, Gerwick, William H, Wolan, Dennis W, Hook, Gregory, O’Donoghue, Anthony J, Hook, Vivian
Published in ACS chemical biology (17.09.2021)
Published in ACS chemical biology (17.09.2021)
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Journal Article
Turning a protein kinase on or off from a single allosteric site via disulfide trapping
Sadowsky, Jack D, Burlingame, Mark A, Wolan, Dennis W, McClendon, Christopher L, Jacobson, Matthew P, Wells, James A
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2011)
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Journal Article
Expanding the Use of Spectral Libraries in Proteomics
Deutsch, Eric W, Perez-Riverol, Yasset, Chalkley, Robert J, Wilhelm, Mathias, Tate, Stephen, Sachsenberg, Timo, Walzer, Mathias, Käll, Lukas, Delanghe, Bernard, Böcker, Sebastian, Schymanski, Emma L, Wilmes, Paul, Dorfer, Viktoria, Kuster, Bernhard, Volders, Pieter-Jan, Jehmlich, Nico, Vissers, Johannes P. C, Wolan, Dennis W, Wang, Ana Y, Mendoza, Luis, Shofstahl, Jim, Dowsey, Andrew W, Griss, Johannes, Salek, Reza M, Neumann, Steffen, Binz, Pierre-Alain, Lam, Henry, Vizcaíno, Juan Antonio, Bandeira, Nuno, Röst, Hannes
Published in Journal of proteome research (07.12.2018)
Published in Journal of proteome research (07.12.2018)
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Journal Article
Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria
Bess, Elizabeth N, Bisanz, Jordan E, Yarza, Fauna, Bustion, Annamarie, Rich, Barry E, Li, Xingnan, Kitamura, Seiya, Waligurski, Emily, Ang, Qi Yan, Alba, Diana L, Spanogiannopoulos, Peter, Nayfach, Stephen, Koliwad, Suneil K, Wolan, Dennis W, Franke, Adrian A, Turnbaugh, Peter J
Published in Nature microbiology (01.01.2020)
Published in Nature microbiology (01.01.2020)
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Journal Article
The Development of the Bengamides as New Antibiotics against Drug-Resistant Bacteria
Porras-Alcalá, Cristina, Moya-Utrera, Federico, García-Castro, Miguel, Sánchez-Ruiz, Antonio, López-Romero, Juan Manuel, Pino-González, María Soledad, Díaz-Morilla, Amelia, Kitamura, Seiya, Wolan, Dennis W., Prados, José, Melguizo, Consolación, Cheng-Sánchez, Iván, Sarabia, Francisco
Published in Marine drugs (31.05.2022)
Published in Marine drugs (31.05.2022)
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Journal Article
Peripheral neuronal activation shapes the microbiome and alters gut physiology
Griffiths, Jessica A., Yoo, Bryan B., Thuy-Boun, Peter, Cantu, Victor J., Weldon, Kelly C., Challis, Collin, Sweredoski, Michael J., Chan, Ken Y., Thron, Taren M., Sharon, Gil, Moradian, Annie, Humphrey, Gregory, Zhu, Qiyun, Shaffer, Justin P., Wolan, Dennis W., Dorrestein, Pieter C., Knight, Rob, Gradinaru, Viviana, Mazmanian, Sarkis K.
Published in Cell reports (Cambridge) (23.04.2024)
Published in Cell reports (Cambridge) (23.04.2024)
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Journal Article
Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia
Garnar-Wortzel, Leopold, Bishop, Timothy R, Kitamura, Seiya, Milosevich, Natalia, Asiaban, Joshua N, Zhang, Xiaoyu, Zheng, Qinheng, Chen, Emily, Ramos, Anissa R, Ackerman, Christopher J, Hampton, Eric N, Chatterjee, Arnab K, Young, Travis S, Hull, Mitchell V, Sharpless, K. Barry, Cravatt, Benjamin F, Wolan, Dennis W, Erb, Michael A
Published in ACS central science (26.05.2021)
Published in ACS central science (26.05.2021)
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Journal Article
Mitochondrial Permeability Transition Causes Mitochondrial Reactive Oxygen Species- and Caspase 3-Dependent Atrophy of Single Adult Mouse Skeletal Muscle Fibers
Skinner, Sarah K, Solania, Angelo, Wolan, Dennis W, Cohen, Michael S, Ryan, Terence E, Hepple, Russell T
Published in Cells (Basel, Switzerland) (29.09.2021)
Published in Cells (Basel, Switzerland) (29.09.2021)
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Journal Article
Selective Inhibition of Initiator versus Executioner Caspases Using Small Peptides Containing Unnatural Amino Acids
Vickers, Chris J, González-Páez, Gonzalo E, Litwin, Kevin M, Umotoy, Jeffrey C, Coutsias, Evangelos A, Wolan, Dennis W
Published in ACS chemical biology (17.10.2014)
Published in ACS chemical biology (17.10.2014)
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Journal Article
Synthetic Elaboration of Native DNA by RASS (SENDR)
Flood, Dillon T, Knouse, Kyle W, Vantourout, Julien C, Kitamura, Seiya, Sanchez, Brittany B, Sturgell, Emily J, Chen, Jason S, Wolan, Dennis W, Baran, Phil S, Dawson, Philip E
Published in ACS central science (28.10.2020)
Published in ACS central science (28.10.2020)
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Journal Article
Proteome-wide covalent ligand discovery in native biological systems
Backus, Keriann M, Correia, Bruno E, Lum, Kenneth M, Forli, Stefano, Horning, Benjamin D, González-Páez, Gonzalo E, Chatterjee, Sandip, Lanning, Bryan R, Teijaro, John R, Olson, Arthur J, Wolan, Dennis W, Cravatt, Benjamin F
Published in Nature (London) (23.06.2016)
Published in Nature (London) (23.06.2016)
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