The ceramide kinase inhibitor NVP‐231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death
Pastukhov, Oleksandr, Schwalm, Stephanie, Zangemeister‐Wittke, Uwe, Fabbro, Doriano, Bornancin, Frederic, Japtok, Lukasz, Kleuser, Burkhard, Pfeilschifter, Josef, Huwiler, Andrea
Published in British journal of pharmacology (01.12.2014)
Published in British journal of pharmacology (01.12.2014)
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Loss of sphingosine kinase‐1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin‐induced DNA damage
Huwiler, Andrea, Kotelevets, Nataliya, Xin, Cuiyan, Pastukhov, Oleksandr, Pfeilschifter, Josef, Zangemeister‐Wittke, Uwe
Published in British journal of pharmacology (01.01.2011)
Published in British journal of pharmacology (01.01.2011)
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Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt
Schwalm, Stephanie, Erhardt, Martin, Römer, Isolde, Pfeilschifter, Josef, Zangemeister-Wittke, Uwe, Huwiler, Andrea
Published in International journal of molecular sciences (19.02.2020)
Published in International journal of molecular sciences (19.02.2020)
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DARPins Recognizing the Tumor-Associated Antigen EpCAM Selected by Phage and Ribosome Display and Engineered for Multivalency
Stefan, Nikolas, Martin-Killias, Patricia, Wyss-Stoeckle, Sascha, Honegger, Annemarie, Zangemeister-Wittke, Uwe, Plückthun, Andreas
Published in Journal of molecular biology (04.11.2011)
Published in Journal of molecular biology (04.11.2011)
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Journal Article
Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation
Belyanskaya, Larisa L., Hopkins‐Donaldson, Sally, Kurtz, Stefanie, Simões‐Wüst, Ana Paula, Yousefi, Shida, Simon, Hans‐Uwe, Stahel, Rolf, Zangemeister‐Wittke, Uwe
Published in International journal of cancer (10.12.2005)
Published in International journal of cancer (10.12.2005)
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Journal Article
Facile Double-Functionalization of Designed Ankyrin Repeat Proteins using Click and Thiol Chemistries
Simon, Manuel, Zangemeister-Wittke, Uwe, Plückthun, Andreas
Published in Bioconjugate chemistry (15.02.2012)
Published in Bioconjugate chemistry (15.02.2012)
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Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation
Filipenko, Iuliia, Schwalm, Stephanie, Reali, Luca, Pfeilschifter, Josef, Fabbro, Doriano, Huwiler, Andrea, Zangemeister-Wittke, Uwe
Published in Biochimica et biophysica acta (01.11.2016)
Published in Biochimica et biophysica acta (01.11.2016)
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Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells
Blanchard, Olivier, Stepanovska, Bisera, Starck, Manuel, Erhardt, Martin, Römer, Isolde, Meyer Zu Heringdorf, Dagmar, Pfeilschifter, Josef, Zangemeister-Wittke, Uwe, Huwiler, Andrea
Published in International journal of molecular sciences (17.05.2018)
Published in International journal of molecular sciences (17.05.2018)
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Induction of apoptosis and enhancement of chemosensitivity in human prostate cancer LNCaP cells using bispecific antisense oligonucleotide targeting Bcl‐2 and Bcl‐xL genes
YAMANAKA, KAZUKI, ROCCHI, PALMA, MIYAKE, HIDEAKI, FAZLI, LADAN, SO, ALAN, ZANGEMEISTER‐WITTKE, UWE, GLEAVE, MARTIN E.
Published in BJU international (01.06.2006)
Published in BJU international (01.06.2006)
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Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer
Graumann, Rebecca, Di Capua, Gabriella A, Oyarzún, Juan E, Vásquez, Marcos A, Liao, Christine, Brañes, Jorge A, Roa, Iván, Casanello, Paola, Corvalán, Alejandro H, Owen, Gareth I, Delgado, Iris, Zangemeister-Wittke, Uwe, Ziegler, Annemarie
Published in PloS one (04.05.2017)
Published in PloS one (04.05.2017)
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High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes
Heine, Markus, Freund, Barbara, Nielsen, Peter, Jung, Caroline, Reimer, Rudolph, Hohenberg, Heinrich, Zangemeister-Wittke, Uwe, Wester, Hans-Juergen, Lüers, Georg H, Schumacher, Udo
Published in PloS one (08.05.2012)
Published in PloS one (08.05.2012)
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AKT/mTOR Pathway Activation and BCL-2 Family Proteins Modulate the Sensitivity of Human Small Cell Lung Cancer Cells to RAD001
MARINOV, Marin, ZIOGAS, Algirdas, ARCARO, Alexandre, PARDO, Olivier E, TAN, Liwen Terence, DHILLON, Tony, MAURI, Francesco A, LANE, Heidi A, LEMOINE, Nicholas R, ZANGEMEISTER-WITTKE, Uwe, SECKL, Michael J
Published in Clinical cancer research (15.02.2009)
Published in Clinical cancer research (15.02.2009)
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Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl‐2 and Bcl‐xL antisense treatment
Hopkins‐Donaldson, Sally, Cathomas, Richard, Simões‐Wüst, A. Paula, Kurtz, Stefanie, Belyanskya, Larisa, Stahel, Rolf A., Zangemeister‐Wittke, Uwe
Published in International journal of cancer (20.08.2003)
Published in International journal of cancer (20.08.2003)
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