Search Results - "Witting, PK" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy

by Dong, Lan-Feng, Jameson, Victoria J.A., Tilly, David, Prochazka, Lubomir, Rohlena, Jakub, Valis, Karel, Truksa, Jaroslav, Zobalova, Renata, Mahdavian, Elahe, Kluckova, Katarina, Stantic, Marina, Stursa, Jan, Freeman, Ruth, Witting, Paul K., Norberg, Erik, Goodwin, Jacob, Salvatore, Brian A., Novotna, Jana, Turanek, Jaroslav, Ledvina, Miroslav, Hozak, Pavel, Zhivotovsky, Boris, Coster, Mark J., Ralph, Stephen J., Smith, Robin A.J., Neuzil, Jiri
Published in Free radical biology & medicine (01.06.2011)

Get full text

Journal Article

Antioxidants protect from atherosclerosis by a heme oxygenase-1 pathway that is independent of free radical scavenging

Antioxidants protect from atherosclerosis by a heme oxygenase-1 pathway that is independent of free radical scavenging

by Wu, Ben J, Kathir, Krishna, Witting, Paul K, Beck, Konstanze, Choy, Katherine, Li, Cheng, Croft, Kevin D, Mori, Trevor A, Tanous, David, Adams, Mark R, Lau, Antony K, Stocker, Roland
Published in The Journal of experimental medicine (17.04.2006)

Get full text

Journal Article

The Peroxidase Activity of a Hemin−DNA Oligonucleotide Complex: Free Radical Damage to Specific Guanine Bases of the DNA

The Peroxidase Activity of a Hemin−DNA Oligonucleotide Complex: Free Radical Damage to Specific Guanine Bases of the DNA

by Travascio, Paola, Witting, Paul K, Mauk, A. Grant, Sen, Dipankar
Published in Journal of the American Chemical Society (21.02.2001)

Get full text

Journal Article

Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1

Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1

by Deng, Yi-Mo, Wu, Ben J, Witting, Paul K, Stocker, Roland
Published in Circulation (New York, N.Y.) (28.09.2004)

Get full text

Journal Article

Mitochondria Play a Central Role in Apoptosis Induced by α-Tocopheryl Succinate, an Agent with Antineoplastic Activity: Comparison with Receptor-Mediated Pro-Apoptotic Signaling

Mitochondria Play a Central Role in Apoptosis Induced by α-Tocopheryl Succinate, an Agent with Antineoplastic Activity: Comparison with Receptor-Mediated Pro-Apoptotic Signaling

by Weber, Tobias, Dalen, Helge, Andera, Ladislav, Nègre-Salvayre, Anne, Augé, Nathalie, Sticha, Martin, Lloret, Ana, Terman, Alexei, Witting, Paul K, Higuchi, Masahiro, Plasilova, Magdalena, Zivny, Jan, Gellert, Nina, Weber, Christian, Neuzil, Jiri
Published in Biochemistry (Easton) (15.04.2003)

Get full text

Journal Article

α‐Tocopheryl succinate selectively induces apoptosis in neuroblastoma cells: potential therapy of malignancies of the nervous system?

α‐Tocopheryl succinate selectively induces apoptosis in neuroblastoma cells: potential therapy of malignancies of the nervous system?

by Swettenham, Emma, Witting, Paul K., Salvatore, Brian A., Neuzil, Jiri
Published in Journal of neurochemistry (01.09.2005)

Get full text

Journal Article

Protective effect of a synthetic anti‐oxidant on neuronal cell apoptosis resulting from experimental hypoxia re‐oxygenation injury

Protective effect of a synthetic anti‐oxidant on neuronal cell apoptosis resulting from experimental hypoxia re‐oxygenation injury

by Rayner, Ben S., Duong, T. T. Hong, Myers, Simon J., Witting, Paul K.
Published in Journal of neurochemistry (01.04.2006)

Get full text

Journal Article

Oxidation of high density lipoproteins. II. Evidence for direct reduction of lipid hydroperoxides by methionine residues of apolipoproteins AI and AII

Oxidation of high density lipoproteins. II. Evidence for direct reduction of lipid hydroperoxides by methionine residues of apolipoproteins AI and AII

by Garner, B, Waldeck, A.R, Witting, P.K, Rye, K.A, Stocker, R
Published in The Journal of biological chemistry (13.03.1998)

Get full text

Journal Article

Oxidants and antioxidants in atherosclerosis

Oxidants and antioxidants in atherosclerosis

by Mashima, R, Witting, P K, Stocker, R
Published in Current opinion in lipidology (01.08.2001)

Get more information

Journal Article

Vitamin E analogs trigger apoptosis in HER2/erbB2-overexpressing breast cancer cells by signaling via the mitochondrial pathway

Vitamin E analogs trigger apoptosis in HER2/erbB2-overexpressing breast cancer cells by signaling via the mitochondrial pathway

by Wang, Xiu-Fang, Witting, Paul K., Salvatore, Brian A., Neuzil, Jiri
Published in Biochemical and biophysical research communications (14.01.2005)

Get full text

Journal Article

Corrigendum to: "Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy" [Free Radic Biol Med. 50 (2011) 1546-1555]

Corrigendum to: "Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy" [Free Radic Biol Med. 50 (2011) 1546-1555]

by Dong, Lan-Feng, Jameson, Victoria J A, Tilly, David, Prochazka, Lubomir, Rohlena, Jakub, Valis, Karel, Truksa, Jaroslav, Zobalova, Renata, Mahdavian, Elahe, Kluckova, Katarina, Stantic, Marina, Stursa, Jan, Freeman, Ruth, Witting, Paul K, Norberg, Erik, Goodwin, Jacob, Salvatore, Brian A, Novotna, Jana, Turanek, Jaroslav, Ledvina, Miroslav, Hozak, Pavel, Zhivotovsky, Boris, Coster, Mark J, Ralph, Stephen J, Smith, Robin A J, Neuzil, Jiri
Published in Free radical biology & medicine (01.12.2013)

Get full text

Journal Article

Reaction of human myoglobin and H2O2. Electron transfer between tyrosine 103 phenoxyl radical and cysteine 110 yields a protein-thiyl radical

Reaction of human myoglobin and H2O2. Electron transfer between tyrosine 103 phenoxyl radical and cysteine 110 yields a protein-thiyl radical

by Witting, P K, Mauk, A G
Published in The Journal of biological chemistry (11.05.2001)

Get full text

Journal Article

Site-Specific Antiatherogenic Effect of Probucol in Apolipoprotein E–Deficient Mice

Site-Specific Antiatherogenic Effect of Probucol in Apolipoprotein E–Deficient Mice

by Witting, Paul K, Pettersson, Knut, Letters, Jacinta, Stocker, Roland
Published in Arteriosclerosis, thrombosis, and vascular biology (01.08.2000)

Get full text

Journal Article

Probucol protects against hypochlorite-induced endothelial dysfunction: identification of a novel pathway of probucol oxidation to a biologically active intermediate

Probucol protects against hypochlorite-induced endothelial dysfunction: identification of a novel pathway of probucol oxidation to a biologically active intermediate

by Witting, Paul K, Wu, Ben J, Raftery, Mark, Southwell-Keely, Peter, Stocker, Roland
Published in The Journal of biological chemistry (22.04.2005)

Get full text

Journal Article

Oxidation of high density lipoproteins. I. Formation of methionine sulfoxide in apolipoproteins AI and AII is an early event that accompanies lipid peroxidation and can be enhanced by alpha-tocopherol

Oxidation of high density lipoproteins. I. Formation of methionine sulfoxide in apolipoproteins AI and AII is an early event that accompanies lipid peroxidation and can be enhanced by alpha-tocopherol

by Garner, B, Witting, P K, Waldeck, A R, Christison, J K, Raftery, M, Stocker, R
Published in The Journal of biological chemistry (13.03.1998)

Get full text

Journal Article

Role of Tyrosine-103 in Myoglobin Peroxidase Activity: Kinetic and Steady-State Studies on the Reaction of Wild-Type and Variant Recombinant Human Myoglobins with H2O2

Role of Tyrosine-103 in Myoglobin Peroxidase Activity: Kinetic and Steady-State Studies on the Reaction of Wild-Type and Variant Recombinant Human Myoglobins with H2O2

by Witting, Paul K, Mauk, A. Grant, Lay, Peter A
Published in Biochemistry (Easton) (24.09.2002)

Get full text

Journal Article

Human S-Nitroso Oxymyoglobin Is a Store of Vasoactive Nitric Oxide

Human S-Nitroso Oxymyoglobin Is a Store of Vasoactive Nitric Oxide

by Rayner, Benjamin S., Wu, Ben-Jing, Raftery, Mark, Stocker, Roland, Witting, Paul K.
Published in The Journal of biological chemistry (18.03.2005)

Get full text

Journal Article

Reaction of human myoglobin and H2O2. Involvement of a thiyl radical produced at cysteine 110

Reaction of human myoglobin and H2O2. Involvement of a thiyl radical produced at cysteine 110

by Witting, P K, Douglas, D J, Mauk, A G
Published in The Journal of biological chemistry (07.07.2000)

Get full text

Journal Article

Reaction of human myoglobin and nitric oxide. Heme iron or protein sulfhydryl (s) nitrosation dependence on the absence or presence of oxygen

Reaction of human myoglobin and nitric oxide. Heme iron or protein sulfhydryl (s) nitrosation dependence on the absence or presence of oxygen

by Witting, P K, Douglas, D J, Mauk, A G
Published in The Journal of biological chemistry (09.02.2001)

Get full text

Journal Article

A DNA Oligonucleotide−Hemin Complex Cleaves t-Butyl Hydroperoxide through a Homolytic Mechanism

A DNA Oligonucleotide−Hemin Complex Cleaves t-Butyl Hydroperoxide through a Homolytic Mechanism

by Witting, Paul K, Travascio, Paula, Sen, Dipankar, Mauk, A. Grant
Published in Inorganic chemistry (10.09.2001)

Get full text

Journal Article