Monocyte response to SARS-CoV-2 protein ORF8 is associated with severe COVID-19 infection in patients with chronic lymphocytic leukemia
Ruan, Gordon J, Wu, Xiaosheng, Gwin, Kimberly A, Manske, Michelle K, Abeykoon, Jithma P, Bhardwaj, Vaishali, Witter, Taylor L, Schellenberg, Matthew J, Rabe, Kari G, Kay, Neil E, Parikh, Sameer A, Witzig, Thomas E
Published in Haematologica (Roma) (01.09.2024)
Published in Haematologica (Roma) (01.09.2024)
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Journal Article
Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in patients with severe COVID-19
Wu, Xiaosheng, Manske, Michelle K., Ruan, Gordon J., Witter, Taylor L., Nowakowski, Kevin E., Abeykoon, Jithma P., Tang, Xinyi, Yu, Yue, Gwin, Kimberly A., Wu, Annie, Taupin, Vanessa, Bhardwaj, Vaishali, Paludo, Jonas, Dasari, Surendra, Dong, Haidong, Ansell, Stephen M., Badley, Andrew D., Schellenberg, Matthew J., Witzig, Thomas E.
Published in iScience (16.06.2023)
Published in iScience (16.06.2023)
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Journal Article
High‐efficiency recombinant protein purification using mCherry and YFP nanobody affinity matrices
Cong, Anh T. Q., Witter, Taylor L., Schellenberg, Matthew J.
Published in Protein science (01.09.2022)
Published in Protein science (01.09.2022)
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Journal Article
Persistent indurated plaques involving the forehead and vulva
Witter, Taylor L., Jing, Frank Z., Aghazadeh Mohandesi, Nessa
Published in International journal of dermatology (01.11.2024)
Published in International journal of dermatology (01.11.2024)
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Journal Article
Structure study reveals active and inactive conformations of protein kinase C B1
Cong, Anh T.Q., Witter, Taylor L., Elizabeth, Bruinsma S., Jayaraman, Swaathi, Dugan, Maria, Hawse, John R., Goetz, Matthew P., Schellenberg, Matthew J.
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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An Ex Vivo Monocyte Stimulation Test Predicts Severity of COVID-19 Infection in Patients with Chronic Lymphocytic Leukemia (CLL)
Ruan, Gordon, Wu, Xiaosheng, Gwin, Kimberly, Manske, Michelle K., Abeykoon, Jithma P., Witter, Taylor L., Schellenberg, Matthew J., Rabe, Kari G, Achenbach, Sara J., Kay, Neil E., Parikh, Sameer A., Witzig, Thomas E.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Secreted Sars-Cov-2 Encoded ORF8 Protein Stimulates Pro-Inflammatory Cytokines and Predicts Severe Clinical Outcome
Manske, Michelle K., Wu, Xiaosheng, Ruan, Gordon, Witter, Taylor L., Gwin, Kimberly, Nowakowski, Kevin E., Abeykoon, Jithma P., Tang, Xinyi, Yu, Yue, Paludo, Jonas, Dasari, Surendra, Ansell, Stephen M., Badley, Andrew D., Schellenberg, Matthew J., Witzig, Thomas E.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
The SARS-CoV-2 encoded ORF8 protein Stimulates Human Monocytes to Produce Pro-Inflammatory Cytokines
Ruan, Gordon J, Wu, Xiaosheng, Manske, Michelle K., Nowakowski, Kevin E., Abeykoon, Jithma P., Tang, Xingyi, Yu, Yue, Witter, Taylor L., Taupin, Vanessa, Paludo, Jonas, Ansell, Stephen M, Badley, Andrew D., Schellenberg, Matthew J., Witzig, Thomas E.
Published in The Journal of immunology (1950) (01.05.2022)
Published in The Journal of immunology (1950) (01.05.2022)
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Abstract P2-24-03: Z-Endoxifen Allosterically Inhibits PKCβI and its Paradoxical Membrane Translocation
Bhattacharya, Sayantani Sarkar, Witter, Taylor L., Cong, Anh T., Bruinsma, Elizabeth S., Jayaraman, Swaathi, Goetz, Matthew P., Hawse, John, Schellenberg, Matthew
Published in Cancer research (Chicago, Ill.) (01.03.2023)
Published in Cancer research (Chicago, Ill.) (01.03.2023)
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Abstract LB051: Protein kinase C beta 1 (PKCβ1) is allosterically inhibited and paradoxically translocated to the membrane by z-endoxifen
Bhattacharya, Sayantani Sarkar, Huynh, Huy V., Farmakes, Jasmin K., Witter, Taylor L., Bruinsma, Elizabeth S., Jayaraman, Swaathi, Cong, Anh T., Hawse, John R., Goetz, Matthew P., Schellenberg, Matthew J.
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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Journal Article
Secreted ORF8 is a pathogenic cause of severe Covid-19 and potentially targetable with select NLRP3 inhibitors
Wu, Xiaosheng, Manske, Michelle K, Ruan, Gordon, Witter, Taylor L, Nowakowski, Kevin E, Abeykoon, Jithma P, Tang, Xinyi, Yu, Yue, Gwin, Kimberly A, Wu, Annie, Taupin, Vanessa, Bhardwaj, Vaishali, Paludo, Jonas, Dasari, Surendra, Dong, Haidong, Ansell, Stephen M, Badley, Andrew D, Schellenberg, Matthew, Witzig, Thomas E
Published in bioRxiv (22.08.2022)
Published in bioRxiv (22.08.2022)
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