Randomized Phase II Trial of Erlotinib With and Without Entinostat in Patients With Advanced Non–Small-Cell Lung Cancer Who Progressed on Prior Chemotherapy
WITTA, Samir E, JOTTE, Robert M, KONDURI, Katrik, NEUBAUER, Marcus A, SPIRA, Alexander I, RUXER, Robert L, VARELLA-GARCIA, Marileila, BUNN, Paul A, HIRSCH, Fred R
Published in Journal of clinical oncology (20.06.2012)
Published in Journal of clinical oncology (20.06.2012)
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Insulin-like Growth Factor Receptor 1 (IGF1R) Gene Copy Number Is Associated With Survival in Operable Non–Small-Cell Lung Cancer: A Comparison Between IGF1R Fluorescent In Situ Hybridization, Protein Expression, and mRNA Expression
DZIADZIUSZKO, Rafal, MERRICK, Daniel T, VARELLA-GARCIA, Marileila, HIRSCH, Fred R, WITTA, Samir E, MENDOZA, Adelita D, SZOSTAKIEWICZ, Barbara, SZYMANOWSKA, Amelia, RZYMAN, Witold, DZIADZIUSZKO, Katarzyna, JASSEM, Jacek, BUNN, Paul A
Published in Journal of clinical oncology (01.05.2010)
Published in Journal of clinical oncology (01.05.2010)
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Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines
Witta, Samir E, Gemmill, Robert M, Hirsch, Fred R, Coldren, Christopher D, Hedman, Karla, Ravdel, Larisa, Helfrich, Barbara, Dziadziuszko, Rafal, Chan, Daniel C, Sugita, Michio, Chan, Zeng, Baron, Anna, Franklin, Wilbur, Drabkin, Harry A, Girard, Luc, Gazdar, Adi F, Minna, John D, Bunn, Jr, Paul A
Published in Cancer research (Chicago, Ill.) (15.01.2006)
Published in Cancer research (Chicago, Ill.) (15.01.2006)
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Journal Article
Baseline Gene Expression Predicts Sensitivity to Gefitinib in Non–Small Cell Lung Cancer Cell Lines
Coldren, Christopher D, Helfrich, Barbara A, Witta, Samir E, Sugita, Michio, Lapadat, Razvan, Zeng, Chan, Barón, Anna, Franklin, Wilbur A, Hirsch, Fred R, Geraci, Mark W, Bunn, Jr, Paul A
Published in Molecular cancer research (01.08.2006)
Published in Molecular cancer research (01.08.2006)
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Epidermal Growth Factor Receptor Messenger RNA Expression, Gene Dosage, and Gefitinib Sensitivity in Non–Small Cell Lung Cancer
DZIADZIUSZKO, Rafal, WITTA, Samir E, VARELLA-GARCIA, Marileila, DANENBERG, Kathleen D, HIRSCH, Fred R, CAPPUZZO, Federico, PARK, Seongjin, TANAKA, Koji, DANENBERG, Peter V, BARON, Anna E, CRINO, Lucio, FRANKLIN, Wilbur A, BUNN, Paul A
Published in Clinical cancer research (15.05.2006)
Published in Clinical cancer research (15.05.2006)
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A Phase I and Pharmacokinetic Study of Exisulind and Docetaxel in Patients with Advanced Solid Tumors
WITTA, Samir E, GUSTAFSON, Daniel L, LONG, Michael E, GIBBS, Amy, KELLY, Karen, BUNN, Paul A, CHAN, Daniel C, PALLANSCH, Patrick, ECKHARDT, S. Gail, PIERSON, A. Scott, MENTER, Alexander, HOLDEN, Scott N, BASCHE, Michele, PERSKY, Martha, O'BRYANT, Cindy L, CHAN ZENG, BARON, Anna
Published in Clinical cancer research (01.11.2004)
Published in Clinical cancer research (01.11.2004)
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Biological markers for non-small cell lung cancer patient selection for epidermal growth factor receptor tyrosine kinase inhibitor therapy
BUNN, Paul A, DZIADZIUSZKO, Rafal, VARELLA-GARCIA, Marileila, FRANKLIN, Wilbur A, WITTA, Samir E, KELLY, Karen, HIRSCH, Fred R
Published in Clinical cancer research (15.06.2006)
Published in Clinical cancer research (15.06.2006)
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Journal Article
Somatic cell cloned transgenic bovine neurons for transplantation in parkinsonian rats
Zawada, W M, Cibelli, J B, Choi, P K, Clarkson, E D, Golueke, P J, Witta, S E, Bell, K P, Kane, J, Ponce de Leon, F A, Jerry, D J, Robl, J M, Freed, C R, Stice, S L
Published in Nature medicine (01.05.1998)
Published in Nature medicine (01.05.1998)
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Improvement of Neurological Deficits in 6-hydroxydopamine-Lesioned Rats after Transplantation with Allogeneic Simian Virus 40 Large Tumor Antigen Gene-Induced Immortalized Dopamine Cells
Clarkson, Edward D., La Rosa, Francisco G., Edwards-Prasad, Judith, Weiland, David A., Witta, Samir E., Freed, Curt R., Prasad, Kedar N.
Published in Proceedings of the National Academy of Sciences - PNAS (03.02.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (03.02.1998)
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HISTONE DEACETYLASE INHIBITORS SENSITIZE CANCER CELLS TO EPIDERMAL GROWTH FACTOR INHIBITORS
WITTA SAMIR E, BUNN PAUL A. JR, GEMMILL ROBERT M, CHAN DANIEL, DRABKIN HARRY A
Year of Publication 23.01.2015
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Year of Publication 23.01.2015
Patent
ErbB-3 expression is associated with E-cadherin and their coexpression restores response to gefitinib in non-small-cell lung cancer (NSCLC)
Witta, S. E., Dziadziuszko, R., Yoshida, K., Hedman, K., Varella-Garcia, M., Bunn, P. A., Hirsch, F. R.
Published in Annals of oncology (01.04.2009)
Published in Annals of oncology (01.04.2009)
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A phase Ib study of CUDC-101, a multitargeted inhibitor of EGFR, HER2, and HDAC, in patients with advanced head and neck, gastric, breast, liver, and non-small cell lung cancer
Fu, Siqing, Nemunaitis, John J., Bessudo, Alberto, Bauman, Julie E., Hamid, Omid, Witta, Samir E., Dy, Grace K., Lai, Cheng, Laliberte, Robert, Voi, Maurizio
Published in Journal of clinical oncology (20.05.2012)
Published in Journal of clinical oncology (20.05.2012)
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Journal Article
Effects of entinostat onresistance to cetuximab and EGFR TKIs in non-small cell lung cancer
Witta, Samir E., Chan, Dan, Girard, Luc, Zheng, Di, Franekova, Veronica, Peyton, Michael, Zhang, Zhi-Yong, Kline, Zoe, Minna, John D., Bunn, Paul A., Hirsch, Fred R.
Published in Journal of clinical oncology (20.05.2012)
Published in Journal of clinical oncology (20.05.2012)
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Abstract 5439: Characterization of the class 1 histone deacetylase inhibitor entinostat in EGFRi acquired resistance models and in combination with cetuximab in NSCLC
Chan, Daniel C., Witta, Samir E., Zheng, Di, Franekova, Veronika, Sui, Xiaomei, Ordentlich, Peter, Bunn, Paul A., Hirsch, Fred R.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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PD2-3-6: ERBB3 expression correlates with vorinostat and gefitinib activity and its co-expression with E-cadherin restores response to gefitinib in NSCLC
Witta, Samir E., Hirsch, Fred R., Lapadat, Razvan, Dziadziuszko, Rafal, Bunn, Paul A.
Published in Journal of thoracic oncology (01.08.2007)
Published in Journal of thoracic oncology (01.08.2007)
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XlPOU 2 , a noggin-inducible gene, has direct neuralizing activity
Witta, Samir E., Agarwal, Veena R., Sato, Sheryl M.
Published in Development (Cambridge) (01.03.1995)
Published in Development (Cambridge) (01.03.1995)
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