Loss of NKG2D in murine NK cells leads to increased perforin production upon long‐term stimulation with IL‐2
Prinz, Daniela, Klein, Klara, List, Julia, Knab, Vanessa M., Menzl, Ingeborg, Leidenfrost, Nicoletta, Heller, Gerwin, Polić, Bojan, Putz, Eva Maria, Witalisz‐Siepracka, Agnieszka, Sexl, Veronika, Gotthardt, Dagmar
Published in European journal of immunology (01.06.2020)
Published in European journal of immunology (01.06.2020)
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Journal Article
Triple-negative breast cancer cells rely on kinase-independent functions of CDK8 to evade NK-cell-mediated tumor surveillance
Knab, Vanessa Maria, Gotthardt, Dagmar, Klein, Klara, Grausenburger, Reinhard, Heller, Gerwin, Menzl, Ingeborg, Prinz, Daniela, Trifinopoulos, Jana, List, Julia, Fux, Daniela, Witalisz-Siepracka, Agnieszka, Sexl, Veronika
Published in Cell death & disease (23.10.2021)
Published in Cell death & disease (23.10.2021)
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Journal Article
PB1783: UNRAVELING THE TUMOR SUPPRESSIVE ROLE OF STAT3B IN ACUTE MYELOID LEUKEMIA
Edtmayer, Sophie, Witalisz‐Siepracka, Agnieszka, Zdársky, Bernhard, Weiss, Stefanie, Fiedler, Kerstin, Eder, Thomas, Poli, Valeria, Grebien, Florian, Stoiber, Dagmar
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Journal Article
PB1805: BREAKING A PARADIGM: LOSS OF STAT3 INCREASES INVASION IN MLL‐AF9‐DRIVEN ACUTE MYELOID LEUKEMIA
Zdársky, Bernhard, Edtmayer, Sophie, Boigenzahn, Stefanie, Witalisz‐Siepracka, Agnieszka, Fiedler, Kerstin, Weiss, Stefanie, Stoiber‐Sakaguchi, Dagmar
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Journal Article
The Multifaceted Role of STAT3 in NK-Cell Tumor Surveillance
Witalisz-Siepracka, Agnieszka, Klein, Klara, Zdársky, Bernhard, Stoiber, Dagmar
Published in Frontiers in immunology (05.07.2022)
Published in Frontiers in immunology (05.07.2022)
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Journal Article
CDK8-Novel Therapeutic Opportunities
Menzl, Ingeborg, Witalisz-Siepracka, Agnieszka, Sexl, Veronika
Published in Pharmaceuticals (Basel, Switzerland) (19.06.2019)
Published in Pharmaceuticals (Basel, Switzerland) (19.06.2019)
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Journal Article
STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion
Gotthardt, Dagmar, Putz, Eva M, Grundschober, Eva, Prchal-Murphy, Michaela, Straka, Elisabeth, Kudweis, Petra, Heller, Gerwin, Bago-Horvath, Zsuzsanna, Witalisz-Siepracka, Agnieszka, Cumaraswamy, Abbarna A, Gunning, Patrick T, Strobl, Birgit, Müller, Mathias, Moriggl, Richard, Stockmann, Christian, Sexl, Veronika
Published in Cancer discovery (01.04.2016)
Published in Cancer discovery (01.04.2016)
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Journal Article
Loss of JAK1 Drives Innate Immune Deficiency
Witalisz-Siepracka, Agnieszka, Klein, Klara, Prinz, Daniela, Leidenfrost, Nicoletta, Schabbauer, Gernot, Dohnal, Alexander, Sexl, Veronika
Published in Frontiers in immunology (08.01.2019)
Published in Frontiers in immunology (08.01.2019)
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Journal Article
Human signal transducer and activator of transcription 5b (STAT5b) mutation causes dysregulated human natural killer cell maturation and impaired lytic function
Vargas-Hernández, Alexander, Witalisz-Siepracka, Agnieszka, Prchal-Murphy, Michaela, Klein, Klara, Mahapatra, Sanjana, Al-Herz, Waleed, Mace, Emily M., Carisey, Alexandre F., Orange, Jordan S., Sexl, Veronika, Forbes, Lisa R.
Published in Journal of allergy and clinical immunology (01.01.2020)
Published in Journal of allergy and clinical immunology (01.01.2020)
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Journal Article
Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses
Trifinopoulos, Jana, List, Julia, Klampfl, Thorsten, Klein, Klara, Prchal-Murphy, Michaela, Witalisz-Siepracka, Agnieszka, Bellutti, Florian, Fava, Luca L, Heller, Gerwin, Stummer, Sarah, Testori, Patricia, Den Boer, Monique L, Boer, Judith M, Marinovic, Sonja, Hoermann, Gregor, Walter, Wencke, Villunger, Andreas, Sicinski, Piotr, Sexl, Veronika, Gotthardt, Dagmar
Published in Haematologica (Roma) (10.10.2024)
Published in Haematologica (Roma) (10.10.2024)
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Journal Article
T Cell-Intrinsic CDK6 Is Dispensable for Anti-Viral and Anti-Tumor Responses In Vivo
Klein, Klara, Witalisz-Siepracka, Agnieszka, Gotthardt, Dagmar, Agerer, Benedikt, Locker, Felix, Grausenburger, Reinhard, Knab, Vanessa Maria, Bergthaler, Andreas, Sexl, Veronika
Published in Frontiers in immunology (24.06.2021)
Published in Frontiers in immunology (24.06.2021)
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Journal Article
The Ups and Downs of STAT Inhibition in Acute Myeloid Leukemia
Moser, Bernhard, Edtmayer, Sophie, Witalisz-Siepracka, Agnieszka, Stoiber, Dagmar
Published in Biomedicines (19.08.2021)
Published in Biomedicines (19.08.2021)
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Journal Article
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia
Edtmayer, Sophie, Witalisz-Siepracka, Agnieszka, Zdársky, Bernhard, Heindl, Kerstin, Weiss, Stefanie, Eder, Thomas, Dutta, Sayantanee, Graichen, Uwe, Klee, Sascha, Sharif, Omar, Wieser, Rotraud, Győrffy, Balázs, Poli, Valeria, Casanova, Emilio, Sill, Heinz, Grebien, Florian, Stoiber, Dagmar
Published in Cell death & disease (28.05.2024)
Published in Cell death & disease (28.05.2024)
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Journal Article
STAT3 in acute myeloid leukemia facilitates natural killer cell-mediated surveillance
Witalisz-Siepracka, Agnieszka, Denk, Clio-Melina, Zdársky, Bernhard, Hofmann, Lorenz, Edtmayer, Sophie, Harm, Theresa, Weiss, Stefanie, Heindl, Kerstin, Hessenberger, Manuel, Summer, Sabrina, Dutta, Sayantanee, Casanova, Emilio, Obermair, Gerald J, Győrffy, Balázs, Putz, Eva Maria, Sill, Heinz, Stoiber, Dagmar
Published in Frontiers in immunology (05.07.2024)
Published in Frontiers in immunology (05.07.2024)
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Journal Article
STAT5BN642H drives transformation of NKT cells: a novel mouse model for CD56+ T-LGL leukemia
Klein, Klara, Witalisz-Siepracka, Agnieszka, Maurer, Barbara, Prinz, Daniela, Heller, Gerwin, Leidenfrost, Nicoletta, Prchal-Murphy, Michaela, Suske, Tobias, Moriggl, Richard, Sexl, Veronika
Published in Leukemia (01.09.2019)
Published in Leukemia (01.09.2019)
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Journal Article
STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity
Meissl, Katrin, Simonović, Natalija, Amenitsch, Lena, Witalisz-Siepracka, Agnieszka, Klein, Klara, Lassnig, Caroline, Puga, Ana, Vogl, Claus, Poelzl, Andrea, Bosmann, Markus, Dohnal, Alexander, Sexl, Veronika, Müller, Mathias, Strobl, Birgit
Published in Frontiers in immunology (11.09.2020)
Published in Frontiers in immunology (11.09.2020)
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Journal Article
NK Cell-Specific CDK8 Deletion Enhances Antitumor Responses
Witalisz-Siepracka, Agnieszka, Gotthardt, Dagmar, Prchal-Murphy, Michaela, Didara, Zrinka, Menzl, Ingeborg, Prinz, Daniela, Edlinger, Leo, Putz, Eva Maria, Sexl, Veronika
Published in Cancer immunology research (01.04.2018)
Published in Cancer immunology research (01.04.2018)
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Journal Article
In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity
Prchal-Murphy, Michaela, Witalisz-Siepracka, Agnieszka, Bednarik, Karoline T, Putz, Eva Maria, Gotthardt, Dagmar, Meissl, Katrin, Sexl, Veronika, Müller, Mathias, Strobl, Birgit
Published in Oncoimmunology (02.11.2015)
Published in Oncoimmunology (02.11.2015)
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Journal Article
Tyrosine kinase 2 – Surveillant of tumours and bona fide oncogene
Leitner, Nicole R., Witalisz-Siepracka, Agnieszka, Strobl, Birgit, Müller, Mathias
Published in Cytokine (Philadelphia, Pa.) (01.01.2017)
Published in Cytokine (Philadelphia, Pa.) (01.01.2017)
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Journal Article