Mechanisms of resistance to selective RET tyrosine kinase inhibitors in RET fusion-positive non-small-cell lung cancer
Lin, J.J., Liu, S.V., McCoach, C.E., Zhu, V.W., Tan, A.C., Yoda, S., Peterson, J., Do, A., Prutisto-Chang, K., Dagogo-Jack, I., Sequist, L.V., Wirth, L.J., Lennerz, J.K., Hata, A.N., Mino-Kenudson, M., Nardi, V., Ou, S.-H.I., Tan, D.S.-W., Gainor, J.F.
Published in Annals of oncology (01.12.2020)
Published in Annals of oncology (01.12.2020)
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2862 The influence of time to objective response on lenvatinib clinical outcomes in the phase 3 SELECT trial
Newbold, K, Sherman, S, Wirth, L.J, Habra, M.A, Rietschel, P, Song, J, Schlumberger, M, Gianoukakis, A
Published in European journal of cancer (1990) (01.09.2015)
Published in European journal of cancer (1990) (01.09.2015)
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Swallowing Function After Proton Beam Therapy for Nasopharyngeal Cancer: A Prospective Study
Goldsmith, T, Holman, A.S, Parambi, R.J, Weyman, E, Busse, P.M, Viscosi, E, Wirth, L.J, Clark, J.R, Rothenberg, S.M, Chan, A.W
Published in International journal of radiation oncology, biology, physics (01.11.2012)
Published in International journal of radiation oncology, biology, physics (01.11.2012)
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Factors Associated With Prolonged Gastrostomy Tube Usage in Patients With Oropharyngeal Cancer Treated With Chemoradiation
Jang, J.W, Parambi, R.J, Goldsmith, T.A, Holman, A.S, Wirth, L.J, Clark, J.R, Busse, P.M, Chan, A.W
Published in International journal of radiation oncology, biology, physics (01.11.2012)
Published in International journal of radiation oncology, biology, physics (01.11.2012)
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Effect of age on the efficacy and safety of lenvatinib for the treatment of 131i-refractory differentiated thyroid cancer in the phase 3 select study
Brose, M, Schlumberger, M, Tahara, M, Wirth, L.J, Robinson, B, Elisei, R, Newbold, K, Kiyota, N, Hoff, A.O, Dutcus, C.E, Heras, B.D.L, Zhu, J, Sherman, S.I, Taylor, M
Published in Journal of geriatric oncology (01.10.2014)
Published in Journal of geriatric oncology (01.10.2014)
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1293P Mechanisms of resistance to selpercatinib in RET activated NSCLC and MTC from the LIBRETTO-001 trial
Solomon, B.J., Drilon, A.E., Wirth, L.J., Szpurka, A., Rao, X., Massey, A.C., Barker, S., Wright, J., Won, H., Cabanillas, M.E.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
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2229P Updated safety and efficacy of selpercatinib in patients (pts) with RET-activated thyroid cancer: Data from LIBRETTO-001
Wirth, L.J., Subbiah, V., Worden, F.P., Solomon, B.J., Robinson, B., Hadoux, J., Tomasini, P., Weiler, D., Deschler-Baier, B., Tan, D.S.W., Lin, Y., Bayt, T., Maeda, P., Drilon, A., Cassier, P.
Published in Annals of oncology (01.10.2023)
Published in Annals of oncology (01.10.2023)
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903P AL101 therapy in patients with recurrent/metastatic (R/M) adenoid cystic carcinoma (ACC): Final ACCURACY trial results and meta-analysis of clinical outcomes
Ferrarotto, R., Bobbili, P., Bowles, D.W., Even, C., Gordon, G., Gutierrez, A., Metcalf, R., Muzaffar, J., Nguyen, C., Oliva, M., Perez, C.A., Rodriguez, C., Sendhil, S.R., Winquist, E., Wirth, L.J., Xia, B., Yovell, J., Ho, A.L.
Published in Annals of oncology (01.10.2023)
Published in Annals of oncology (01.10.2023)
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LBA3 Randomized phase III study of selpercatinib versus cabozantinib or vandetanib in advanced, kinase inhibitor-naïve, RET-mutant medullary thyroid cancer
Hadoux, J., Elisei, R., Brose, M.S., Hoff, A., Robinson, B., Gao, M., Jarzab, B., Isaev, P., Kopeckova, K., Wadsley, J., Führer, D., Keam, B., Sherman, E.J., Tahara, M., Hu, M.I., Lin, Y., Maeda, P., Wirth, L.J., Capdevila Castillon, J.
Published in Annals of oncology (01.10.2023)
Published in Annals of oncology (01.10.2023)
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1656P Durable efficacy of selpercatinib in patients (pts) with medullary thyroid cancer (MTC): Update of the LIBRETTO-001 trial
Kroiss, M., Sherman, E.J., Wirth, L.J., Cabanillas, M.E., Robinson, B., Subbiah, V., Drilon, A.E., Godbert, Y., Fasnacht, N., Soldatenkova, V., Xia, M.S., Duann, C-W., Wright, J., Weiler-Bisig, D., Shah, M.
Published in Annals of oncology (01.09.2022)
Published in Annals of oncology (01.09.2022)
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ACCURACY a phase (P) II trial of AL101, a pan-Notch inhibitor, in recurrent/metastatic (R/M) adenoid cystic carcinoma (ACC) patients (pts) with Notch activating mutations (Notch act mut): Preliminary safety and efficacy data
Ferrarotto, R., Ho, A., Wirth, L.J., Muzaffar, J., Rodriguez, C., Dekel, E., Walker, R.M., Nadri-Shay, C., Vergara-Silva, A.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Impact of lung metastasis on overall survival (OS) in the phase III SELECT study with lenvatinib (LEN) in patients (pts) with radioiodine refractory differentiated thyroid cancer (RR-DTC)
Tahara, M., Kiyota, N., Hoff, A.O., Badiu, C., Owonikoko, T.K., Dutcus, C.E., Suzuki, T., Ren, M., Misir, S., Wirth, L.J.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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1862PD - Impact of lung metastasis on overall survival (OS) in the phase III SELECT study with lenvatinib (LEN) in patients (pts) with radioiodine refractory differentiated thyroid cancer (RR-DTC)
Tahara, M., Kiyota, N., Hoff, A.O., Badiu, C., Owonikoko, T.K., Dutcus, C.E., Suzuki, T., Ren, M., Misir, S., Wirth, L.J.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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1148P - ACCURACY a phase (P) II trial of AL101, a pan-Notch inhibitor, in recurrent/metastatic (R/M) adenoid cystic carcinoma (ACC) patients (pts) with Notch activating mutations (Notch act mut): Preliminary safety and efficacy data
Ferrarotto, R., Ho, A., Wirth, L.J., Muzaffar, J., Rodriguez, C., Dekel, E., Walker, R.M., Nadri-Shay, C., Vergara-Silva, A.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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1292P Exploratory patient-reported outcomes (PROs) among patients with RET-fusion non-small cell lung cancer (NSCLC) in LIBRETTO-001: A phase I/II trial of selpercatinib
Minchom, A.R., Tan, D.S.W., Massarelli, E., Subbiah, V., Boni, V., Robinson, B., Wirth, L.J., Hess, L.M., Huang, X., Kherani, J.F., Olek, E., McCoach, C.
Published in Annals of oncology (01.09.2020)
Published in Annals of oncology (01.09.2020)
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919MO ACCURACY a phase II trial of AL101, a selective gamma secretase inhibitor, in subjects with recurrent/metastatic (R/M) adenoid cystic carcinoma (ACC) harboring Notch activating mutations (Notchmut)
Ferrarotto, R., Wirth, L.J., Muzaffar, J., Rodriguez, C.P., Xia, B., Perez, C.A., Bowles, D.W., Winquist, E., Hotte, S.J., Metcalf, R., Even, C., Gordon, G.B., Gordon, G., Ho, A.
Published in Annals of oncology (01.09.2020)
Published in Annals of oncology (01.09.2020)
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1922P Exploratory patient-reported outcomes among patients with RET-mutant medullary thyroid cancer in LIBRETTO-001: A phase I/II trial of selpercatinib (LOXO-292)
Wirth, L.J., Robinson, B., Boni, V., Tan, D.S.W., McCoach, C., Massarelli, E., Hess, L.M., Huang, X., Kherani, J.F., Olek, E., Subbiah, V.
Published in Annals of oncology (01.09.2020)
Published in Annals of oncology (01.09.2020)
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1917P Pembrolizumab salvage add-on therapy in patients with radioiodine-refractory (RAIR), progressive differentiated thyroid cancer (DTC) progressing on lenvatinib: Results of a multicenter phase II International Thyroid Oncology Group Trial
Haugen, B., French, J.D., Worden, F., Konda, B., Sherman, E.J., Dadu, R., Gianoukakis, A.G., Mccue, S., Foster, N., Bowles, D.W., Wirth, L.J.
Published in Annals of oncology (01.09.2020)
Published in Annals of oncology (01.09.2020)
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904P ACCURACY: A phase II trial of AL101, a selective gamma secretase inhibitor, in subjects with recurrent/metastatic (R/M) adenoid cystic carcinoma (ACC) harboring Notch activating mutations (Notchmut): Results of 6-mg cohort
Ho, A.L., Bowles, D.W., Even, C., Hao, D., Kang, H., Metcalf, R., Muzaffar, J., Oliva, M., Perez, C.A., Popovtzer, A., Rodriguez, C.P., Stemmer, S.M., Van Herpen, C.M., Winquist, E., Wirth, L.J., Worden, F.P., Xia, B., Gordon, G., Gordon, G.B., Ferrarotto, R.
Published in Annals of oncology (01.09.2021)
Published in Annals of oncology (01.09.2021)
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1654P Updated ARROW data: Pralsetinib in patients (pts) with advanced or metastatic RET-altered thyroid cancer (TC)
Hu, M.I., Subbiah, V., Mansfield, A.S., Taylor, M., Schuler, M.H.H., Zhu, V., Hadoux, J., Curigliano, G., Wirth, L.J., Garralda, E., Adkins, D.R., Godbert, Y., Ahn, M-J., Cassier, P.A., Cho, B.C., Lin, C-C., Barata, T., Zalutskaya, A., Scalori, A., Brose, M.S.
Published in Annals of oncology (01.09.2022)
Published in Annals of oncology (01.09.2022)
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