Improving prescribing: a feasibility study of pharmacogenetic testing with clinical decision support in primary healthcare in Singapore
Smith, Helen, Dawes, Martin, Katzov-Eckert, Hagit, Burrell, Sarah, Xin Hui, Sam, Winther, Michael D
Published in Family practice (23.11.2022)
Published in Family practice (23.11.2022)
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Prevalence and characteristics of adverse drug reactions at admission to hospital: a prospective observational study
Chan, Sze Ling, Ang, Xiaohui, Sani, Levana L., Ng, Hong Yen, Winther, Michael D., Liu, Jian Jun, Brunham, Liam R., Chan, Alexandre
Published in British journal of clinical pharmacology (01.12.2016)
Published in British journal of clinical pharmacology (01.12.2016)
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Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: a randomized controlled trial
Syn, Nicholas L, Wong, Andrea Li-Ann, Lee, Soo-Chin, Teoh, Hock-Luen, Yip, James Wei Luen, Seet, Raymond Cs, Yeo, Wee Tiong, Kristanto, William, Bee, Ping-Chong, Poon, L M, Marban, Patrick, Wu, Tuck Seng, Winther, Michael D, Brunham, Liam R, Soong, Richie, Tai, Bee-Choo, Goh, Boon-Cher
Published in BMC medicine (10.07.2018)
Published in BMC medicine (10.07.2018)
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Economic burden of adverse drug reactions and potential for pharmacogenomic testing in Singaporean adults
Chan, Sze Ling, Ng, Hong Yen, Sung, Cynthia, Chan, Alexandre, Winther, Michael D, Brunham, Liam R, Wee, Hwee-Lin
Published in The pharmacogenomics journal (01.08.2019)
Published in The pharmacogenomics journal (01.08.2019)
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Journal Article
Southeast Asian Pharmacogenomics Research Network (SEAPharm): Current Status and Perspectives
Chumnumwat, Supatat, Lu, Zen Huat, Sukasem, Chonlaphat, Winther, Michael David, Capule, Francis R, Abdul Hamid, Asma A Apos Tiyah, Bhandari, Bibek, Chaikledkaew, Usa, Chanhom, Noppadol, Chantarangsu, Soranun, Charoenyingwattana, Angkana, Hang, Tong Thi, Hlaing, Tin Maung, Htun, Kyaw Soe, Jittikoon, Jiraphun, Le, Ly, Mahasirimongkol, Surakameth, Mohamed Noor, Dzul Azri, Shrestha, Jesus, Suwannoi, Lakkana, Tragulpiankit, Pramote, Turongkaravee, Saowalak, Wattanapokayakit, Sukanya, Xangsayarath, Phonepadith, Yuliwulandari, Rika, Zain, Shamsul Mohd, Chantratita, Wasun
Published in Public health genomics (2019)
Published in Public health genomics (2019)
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Journal Article
In search of a genetic explanation for LDLc variability in an FH family: common SNPs and a rare mutation in MTTP explain only part of LDL variability in an FH family[S]
Winther, Michael, Shpitzen, Shoshi, Yaacov, Or, Landau, Jakob, Oren, Limor, Foroozan-Rosenberg, Linda, Lev Cohain, Naama, Schurr, Daniel, Meiner, Vardiela, Szalat, Auryan, Carmi, Shai, Hayden, Michael R., Leitersdorf, Eran, Durst, Ronen
Published in Journal of lipid research (01.10.2019)
Published in Journal of lipid research (01.10.2019)
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Journal Article
Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands
Meingassner, Josef G., Aschauer, Heinrich, Winiski, Anthony P., Dales, Natalie, Yowe, David, Winther, Michael D., Zhang, Zaihui, Stütz, Anton, Billich, Andreas
Published in Journal of investigative dermatology (01.08.2013)
Published in Journal of investigative dermatology (01.08.2013)
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Journal Article
Discovery of XEN445: A potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice
Sun, Shaoyi, Dean, Richard, Jia, Qi, Zenova, Alla, Zhong, Jing, Grayson, Celene, Xie, Clark, Lindgren, Andrea, Samra, Pritpaul, Sojo, Luis, van Heek, Margaret, Lin, Linus, Percival, David, Fu, Jian-min, Winther, Michael D., Zhang, Zaihui
Published in Bioorganic & medicinal chemistry (15.12.2013)
Published in Bioorganic & medicinal chemistry (15.12.2013)
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Journal Article
Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases
Sun, Shaoyi, Zhang, Zaihui, Kodumuru, Vishnumurthy, Pokrovskaia, Natalia, Fonarev, Julia, Jia, Qi, Leung, Po-Yee, Tran, Jennifer, Ratkay, Leslie G., McLaren, David G., Radomski, Chris, Chowdhury, Sultan, Fu, Jianmin, Hubbard, Brian, Winther, Michael D., Dales, Natalie A.
Published in Bioorganic & medicinal chemistry letters (15.01.2014)
Published in Bioorganic & medicinal chemistry letters (15.01.2014)
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Journal Article
Discovery of Piperazin-1-ylpyridazine-Based Potent and Selective Stearoyl-CoA Desaturase‑1 Inhibitors for the Treatment of Obesity and Metabolic Syndrome
Zhang, Zaihui, Sun, Shaoyi, Kodumuru, Vishnumurthy, Hou, Duanjie, Liu, Shifeng, Chakka, Nagasree, Sviridov, Serguei, Chowdhury, Sultan, McLaren, David G, Ratkay, Leslie G, Khakh, Kuldip, Cheng, Xing, Gschwend, Heinz W, Kamboj, Rajender, Fu, Jianmin, Winther, Michael D
Published in Journal of medicinal chemistry (24.01.2013)
Published in Journal of medicinal chemistry (24.01.2013)
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Journal Article
Discovery of thiazolylpyridinone SCD1 inhibitors with preferential liver distribution and reduced mechanism-based adverse effects
Sun, Shaoyi, Zhang, Zaihui, Raina, Vandna, Pokrovskaia, Natalia, Hou, Duanjie, Namdari, Rostam, Khakh, Kuldip, Ratkay, Leslie G., McLaren, David G., Mork, Monica, Fu, Jianmin, Ferreira, Suzie, Hubbard, Brian, Winther, Michael D., Dales, Natalie
Published in Bioorganic & medicinal chemistry letters (15.01.2014)
Published in Bioorganic & medicinal chemistry letters (15.01.2014)
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Journal Article
Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans[S]
Singaraja, Roshni R., Tietjen, Ian, Hovingh, G. Kees, Franchini, Patrick L., Radomski, Chris, Wong, Kenny, vanHeek, Margaret, Stylianou, Ioannis M., Lin, Linus, Wang, Liangsu, Mitnaul, Lyndon, Hubbard, Brian, Winther, Michael, Mattice, Maryanne, Legendre, Annick, Sherrington, Robin, Kastelein, John J., Akinsanya, Karen, Plump, Andrew, Hayden, Michael R.
Published in Journal of lipid research (01.08.2014)
Published in Journal of lipid research (01.08.2014)
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Journal Article
Discovery of triazolone derivatives as novel, potent stearoyl-CoA desaturase-1 (SCD1) inhibitors
Sun, Shaoyi, Zhang, Zaihui, Pokrovskaia, Natalia, Chowdhury, Sultan, Jia, Qi, Chang, Elaine, Khakh, Kuldip, Kwan, Rainbow, McLaren, David G., Radomski, Chris C., Ratkay, Leslie G., Fu, Jianmin, Dales, Natalie A., Winther, Michael D.
Published in Bioorganic & medicinal chemistry (01.02.2015)
Published in Bioorganic & medicinal chemistry (01.02.2015)
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The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans
Singaraja, Roshni R, Sivapalaratnam, Suthesh, Hovingh, Kees, Dubé, Marie-Pierre, Castro-Perez, José, Collins, Heidi L, Adelman, Steven J, Riwanto, Meliana, Manz, Jasmin, Hubbard, Brian, Tietjen, Ian, Wong, Kenny, Mitnaul, Lyndon J, van Heek, Margaret, Lin, Linus, Roddy, Thomas A, McEwen, Jason, Dallinge-Thie, Geesje, van Vark-van der Zee, Leonie, Verwoert, Germaine, Winther, Michael, van Duijn, Cornelia, Hofman, Albert, Trip, Mieke D, Marais, A David, Asztalos, Bela, Landmesser, Ulf, Sijbrands, Eric, Kastelein, John J, Hayden, Michael R
Published in Circulation. Cardiovascular genetics (01.02.2013)
Published in Circulation. Cardiovascular genetics (01.02.2013)
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Use of bioanalyzer electropherograms for quality control and target evaluation in microarray expression profiling studies of ocular tissues
Harrington, Christina A., Winther, Michael, Garred, Michelle M.
Published in Journal of ocular biology, diseases, and informatics (12.12.2009)
Published in Journal of ocular biology, diseases, and informatics (12.12.2009)
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