Selective RET kinase inhibition for patients with RET-altered cancers
Subbiah, V., Velcheti, V., Tuch, B.B., Ebata, K., Busaidy, N.L., Cabanillas, M.E., Wirth, L.J., Stock, S., Smith, S., Lauriault, V., Corsi-Travali, S., Henry, D., Burkard, M., Hamor, R., Bouhana, K., Winski, S., Wallace, R.D., Hartley, D., Rhodes, S., Reddy, M., Brandhuber, B.J., Andrews, S., Rothenberg, S.M., Drilon, A.
Published in Annals of oncology (01.08.2018)
Published in Annals of oncology (01.08.2018)
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391 LOXO-101, a pan TRK inhibitor, for the treatment of TRK-driven cancers
Winski, S, Baer, B, Hartley, D, Rhodes, S, Wallace, R, Smith, S, Nanda, N, Kunkle, L, Lee, P, Bouhana, K
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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The development of LOXO-195, a second generation TRK kinase inhibitor that overcomes acquired resistance to 1st generation inhibitors observed in patients with TRK-fusion cancers
Blake, J, Kolakowski, G.R, Tuch, B, Ebata, K, Brandhuber, B, Winski, S, Bouhana, K, Nanda, N, Wu, W.I, Parker, A, Hamor, R, Larsen, P.D, Sullivan, F, DeWolf, W, Neitzel, N, Wollenberg, L, Andrews, S, Rothenberg, S.M
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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The development of a potent, KDR/VEGFR2-sparing RET kinase inhibitor for treating patients with RET-dependent cancers
Brandhuber, B, Haas, J, Tuch, B, Ebata, K, Bouhana, K, McFaddin, E, Williams, L, Winski, S, Brown, E, Burkhard, M, Nanda, N, Hamor, R, Sullivan, F, Hanson, L, Morales, T, Vigers, G, Wallace, R.D, Blake, J, Andrews, S, Rothenberg, S.M
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent
WINSKI, S. L, HARGREAVES, R. H. J, BUTLER, J, ROSS, D
Published in Clinical cancer research (01.12.1998)
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Published in Clinical cancer research (01.12.1998)
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Characterization of a Mechanism-Based Inhibitor of NAD(P)H:Quinone Oxidoreductase 1 by Biochemical, X-ray Crystallographic, and Mass Spectrometric Approaches
Winski, Shannon L, Faig, Margarita, Bianchet, Mario A, Siegel, David, Swann, Elizabeth, Fung, Kim, Duncan, Mark W, Moody, Christopher J, Amzel, L. Mario, Ross, David
Published in Biochemistry (Easton) (18.12.2001)
Published in Biochemistry (Easton) (18.12.2001)
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Rapid Polyubiquitination and Proteasomal Degradation of a Mutant Form of NAD(P)H:Quinone Oxidoreductase 1
Siegel, D, Anwar, A, Winski, S L, Kepa, J K, Zolman, K L, Ross, D
Published in Molecular pharmacology (01.02.2001)
Published in Molecular pharmacology (01.02.2001)
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Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones
WINSKI, Shannon L, SWANN, Elizabeth, HARGREAVES, Robert H. J, DEHN, Donna L, BUTLER, John, MOODY, Christopher J, ROSS, David
Published in Biochemical pharmacology (15.06.2001)
Published in Biochemical pharmacology (15.06.2001)
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162 MEK162 (ARRY-162), a novel MEK 1/2 inhibitor, inhibits tumor growth regardless of KRas/Raf pathway mutations
Winski, S, Anderson, D, Bouhana, K, Impastato, R, Woessner, R, Zuzack, J, Tunquist, B, Garrus, J, Pheneger, T, Lee, P
Published in European journal of cancer supplements (2010)
Published in European journal of cancer supplements (2010)
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Pre-clinical In Vitro and In Vivo Characterization of a Novel EGFR Sparing ErbB2 Inhibitor with Activity Against Oncogenic ErbB2 Mutations
Chicarelli, M.J., Bouhana, K., Cable, L., Crow, M., Fell, B., Fischer, J., Fulton, J., Guarnieri, A., Jalluri, R., Robinson, J., Sullivan, F., Winski, S., Zhou, Y.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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In Vivo Pre-clinical characterization of a Novel Series of FGFR2 Selective Inhibitors with Potency Against Clinically Relevant Mutations
Fischer, J., Bouhana, K., Chicarelli, M.J., Dahlke, J., Fell, B., Fulton, J., Guarnieri, A., Haygood, L., Jalluri, R., Johnson, A., McLean, B., Max, M., Rieger, R., Robinson, J., Rodriguez, M., Sullivan, F., Wang, Y., Winski, S., Zhou, Y.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Differential Involvement of Caspases in Hydroquinone-Induced Apoptosis in Human Leukemic HL-60 and Jurkat Cells
Inayat-Hussain, Salmaan H., Winski, Shannon L., Ross, David
Published in Toxicology and applied pharmacology (01.09.2001)
Published in Toxicology and applied pharmacology (01.09.2001)
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Conference Proceeding
Genotype-phenotype relationships in studies of a polymorphism in NAD(P)H:quinone oxidoreductase 1
Siegel, D, McGuinness, S M, Winski, S L, Ross, D
Published in Pharmacogenetics (London) (01.02.1999)
Published in Pharmacogenetics (London) (01.02.1999)
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441 - The development of a potent, KDR/VEGFR2-sparing RET kinase inhibitor for treating patients with RET-dependent cancers
Brandhuber, B., Haas, J., Tuch, B., Ebata, K., Bouhana, K., McFaddin, E., Williams, L., Winski, S., Brown, E., Burkhard, M., Nanda, N., Hamor, R., Sullivan, F., Hanson, L., Morales, T., Vigers, G., Wallace, R.D., Blake, J., Andrews, S., Rothenberg, S.M.
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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Journal Article
442 - The development of LOXO-195, a second generation TRK kinase inhibitor that overcomes acquired resistance to 1st generation inhibitors observed in patients with TRK-fusion cancers
Blake, J., Kolakowski, G.R., Tuch, B., Ebata, K., Brandhuber, B., Winski, S., Bouhana, K., Nanda, N., Wu, W.I., Parker, A., Hamor, R., Larsen, P.D., Sullivan, F., DeWolf, W., Neitzel, N., Wollenberg, L., Andrews, S., Rothenberg, S.M.
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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Journal Article