Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation
WINKLER, I. G, PETTIT, A. R, LEVESQUE, J.-P, RAGGATT, L. J, JACOBSEN, R. N, FORRISTAL, C. E, BARBIER, V, NOWLAN, B, CISTERNE, A, BENDALL, L. J, SIMS, N. A
Published in Leukemia (01.07.2012)
Published in Leukemia (01.07.2012)
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Mobilization of bone marrow-derived progenitors
Lévesque, J-P, Winkler, I G, Larsen, S R, Rasko, J E J
Published in Handbook of experimental pharmacology (2007)
Published in Handbook of experimental pharmacology (2007)
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HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α
Forristal, C E, Nowlan, B, Jacobsen, R N, Barbier, V, Walkinshaw, G, Walkley, C R, Winkler, I G, Levesque, J P
Published in Leukemia (01.06.2015)
Published in Leukemia (01.06.2015)
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Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML
Forristal, C E, Brown, A L, Helwani, F M, Winkler, I G, Nowlan, B, Barbier, V, Powell, R J, Engler, G A, Diakiw, S M, Zannettino, A C W, Martin, S, Pattabiraman, D, D'Andrea, R J, Lewis, I D, Levesque, J P
Published in Leukemia (01.10.2015)
Published in Leukemia (01.10.2015)
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B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2
Winkler, Ingrid G, Bendall, Linda J, Forristal, Catherine E, Helwani, Falak, Nowlan, Bianca, Barbier, Valerie, Shen, Yi, Cisterne, Adam, Sedger, Lisa M, Levesque, Jean-Pierre
Published in Haematologica (Roma) (01.03.2013)
Published in Haematologica (Roma) (01.03.2013)
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Detection and Molecular Characterisation of Feline Foamy Virus Serotypes in Naturally Infected Cats
Winkler, I.G., Flügel, R.M., Löchelt, M., Flower, R.L.P.
Published in Virology (New York, N.Y.) (01.08.1998)
Published in Virology (New York, N.Y.) (01.08.1998)
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Construction of Infectious Feline Foamy Virus Genomes: Cat Antisera Do Not Cross-Neutralize Feline Foamy Virus Chimera with Serotype-Specific Env Sequences
Zemba, Motomi, Alke, Alexandra, Bodem, Jochen, Winkler, Ingrid G., Flower, Robert L.P., Pfrepper, K.-I., Delius, Hajo, Flügel, Rolf M., Löchelt, Martin
Published in Virology (New York, N.Y.) (05.01.2000)
Published in Virology (New York, N.Y.) (05.01.2000)
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HIF-1[alpha] is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1[alpha]
Forristal, C.E, Nowlan, B, Jacobsen, R.N, Barbier, V, Walkinshaw, G, Walkley, C.R, Winkler, I.G, Levesque, J.P
Published in Leukemia (01.06.2015)
Published in Leukemia (01.06.2015)
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Journal Article
Hypoxia inducible factor (HIF)-2[alpha] accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML
ristal, C E, Brown, A L, Helwani, F M, Winkler, I G, Nowlan, B, Barbier, V, Powell, R J, Engler, G A, Diakiw, S M, Zannettino, A C W, Martin, S, Pattabiraman, D, D'andrea, R J, Lewis, I D, Levesque, J P
Published in Leukemia (01.10.2015)
Published in Leukemia (01.10.2015)
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Journal Article
OsteoMacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization
Pettit, A R, Sims, NA, Winkler, I G, Alexander, KA, Helwani, F, Raggatt, LJ, Levesque, J P
Published in Bone (New York, N.Y.) (01.05.2009)
Published in Bone (New York, N.Y.) (01.05.2009)
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Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment
Lévesque, Jean-Pierre, Hendy, Jean, Takamatsu, Yasushi, Williams, Brenda, Winkler, Ingrid G, Simmons, Paul J
Published in Experimental hematology (01.05.2002)
Published in Experimental hematology (01.05.2002)
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Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells
Lévesque, Jean-Pierre, Hendy, Jean, Winkler, Ingrid G, Takamatsu, Yasushi, Simmons, Paul J
Published in Experimental hematology (01.02.2003)
Published in Experimental hematology (01.02.2003)
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Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization
Winkler, Ingrid G, Hendy, Jean, Coughlin, Paul, Horvath, Anita, Lévesque, Jean-Pierre
Published in The Journal of experimental medicine (04.04.2005)
Published in The Journal of experimental medicine (04.04.2005)
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