In-vitro and in-vivo assessment of nirmatrelvir penetration into CSF, central nervous system cells, tissues, and peripheral blood mononuclear cells
Avedissian, Sean N., Malik, Johid R., Podany, Anthony T., Neely, Michael, Rhodes, Nathaniel J., Scarsi, Kimberly K., Scheetz, Marc H., Duryee, Michael J., Modebelu, Ukamaka O., Mykris, Timothy M., Winchester, Lee C., Byrareddy, Siddappa N., Fletcher, Courtney V.
Published in Scientific reports (10.05.2024)
Published in Scientific reports (10.05.2024)
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Journal Article
CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection
Harwood, Olivia E, Matschke, Lea M, Moriarty, Ryan V, Balgeman, Alexis J, Weaver, Abigail J, Ellis-Connell, Amy L, Weiler, Andrea M, Winchester, Lee C, Fletcher, Courtney V, Friedrich, Thomas C, Keele, Brandon F, O'Connor, David H, Lang, Jessica D, Reynolds, Matthew R, O'Connor, Shelby L
Published in PLoS pathogens (01.09.2023)
Published in PLoS pathogens (01.09.2023)
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Journal Article
An Efficient Humanized Mouse Model for Oral Anti-Retroviral Administration
Virdi, Amber K, Ho, Sang, Seaton, Melanie S, Olali, Arnold Z, Narasipura, Srinivas D, Barbian, Hannah J, Olivares, Leannie J, Gonzalez, Hemil, Winchester, Lee C, Podany, Anthony T, Ross, Ryan D, Al-Harthi, Lena, Wallace, Jennillee
Published in Cells (Basel, Switzerland) (28.03.2023)
Published in Cells (Basel, Switzerland) (28.03.2023)
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Journal Article
Cross-validation of a high-performance liquid chromatography nevirapine plasma assay in a resource-limited setting in Zimbabwe
Makita-Chingombe, Faithful, Podany, Anthony T, Mykris, Timothy, Muzambi, Farai, Browne, Richard W, Ocque, Andrew J, DiFrancesco, Robin, Winchester, Lee C, Fletcher, Courtney V, Mudzviti, Tinashe, Maponga, Charles C, Morse, Gene D
Published in African journal of laboratory medicine (2021)
Published in African journal of laboratory medicine (2021)
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Journal Article
The Lymphoid Tissue Pharmacokinetics of Tenofovir Disoproxil Fumarate and Tenofovir Alafenamide in HIV-Infected Persons
Fletcher, Courtney V, Podany, Anthony T, Thorkelson, Ann, Winchester, Lee C, Mykris, Timothy, Anderson, Jodi, Jorstad, Siri, Baker, Jason V, Schacker, Timothy W
Published in Clinical pharmacology and therapeutics (01.11.2020)
Published in Clinical pharmacology and therapeutics (01.11.2020)
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Journal Article
Alterations in P-Glycoprotein Expression and Function Between Macrophage Subsets
Cory, Theodore J., He, Hui, Winchester, Lee C., Kumar, Santosh, Fletcher, Courtney V.
Published in Pharmaceutical research (01.11.2016)
Published in Pharmaceutical research (01.11.2016)
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Journal Article
Hepatocytic transcriptional signatures predict comparative drug interaction potential of rifamycin antibiotics
Dyavar, Shetty Ravi, Mykris, Timothy M., Winchester, Lee C., Scarsi, Kimberly K., Fletcher, Courtney V., Podany, Anthony T.
Published in Scientific reports (28.07.2020)
Published in Scientific reports (28.07.2020)
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Journal Article
Quantification of nine antiretroviral drugs in cerebrospinal fluid: An approach to overcome sample collection tube adsorption
Mykris, Timothy M., Weinhold, Jonathan, Winchester, Lee C., Scarsi, Kimberly K., Fletcher, Courtney V., Podany, Anthony T., Avedissian, Sean N.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.07.2023)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.07.2023)
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Journal Article
Assessing the lymphoid tissue bioavailability of antiretrovirals in human primary lymphoid endothelial cells and in mice
Dyavar, Shetty Ravi, Gautam, Nagsen, Podany, Anthony T, Winchester, Lee C, Weinhold, Jonathan A, Mykris, Timothy M, Campbell, Kayla M, Alnouti, Yazen, Fletcher, Courtney V
Published in Journal of antimicrobial chemotherapy (01.10.2019)
Published in Journal of antimicrobial chemotherapy (01.10.2019)
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Journal Article
Intramuscular and subcutaneous administration of antiretroviral drugs, compared with oral, enhances delivery to lymphoid tissues in BALB/c mice
Dyavar, Shetty Ravi, Kumar, Sushil, Gautam, Nagsen, Podany, Anthony T, Winchester, Lee C, Weinhold, Jonathan A, Mykris, Timothy M, Nallasamy, Palanisamy, Alnouti, Yazen, Fletcher, Courtney V
Published in Journal of antimicrobial chemotherapy (01.10.2021)
Published in Journal of antimicrobial chemotherapy (01.10.2021)
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Journal Article
Adipocytes impair efficacy of antiretroviral therapy
Couturier, Jacob, Winchester, Lee C., Suliburk, James W., Wilkerson, Gregory K., Podany, Anthony T., Agarwal, Neeti, Xuan Chua, Corrine Ying, Nehete, Pramod N., Nehete, Bharti P., Grattoni, Alessandro, Sastry, K. Jagannadha, Fletcher, Courtney V., Lake, Jordan E., Balasubramanyam, Ashok, Lewis, Dorothy E.
Published in Antiviral research (01.06.2018)
Published in Antiviral research (01.06.2018)
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Journal Article
Comparison of etonogestrel bioanalytical assay results in plasma and serum within and across laboratories
Sunagawa, Shawnalyn W., Winchester, Lee C., Wichman, Christopher S., Avedissian, Sean N., Erikson, David W., Kernan, Molly, Marzinke, Mark A., Mykris, Timothy M., Nandakumar, Renu, Nolin, Thomas D., Podany, Anthony T., West, Raymond E., Chen, Beatrice A., Chappell, Catherine A., Scarsi, Kimberly K.
Published in Contraception (Stoneham) (01.10.2024)
Published in Contraception (Stoneham) (01.10.2024)
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Journal Article
Normalization of cell associated antiretroviral drug concentrations with a novel RPP30 droplet digital PCR assay
Dyavar, Shetty Ravi, Ye, Zhen, Byrareddy, Siddappa N., Scarsi, Kimberly K., Winchester, Lee C., Weinhold, Jonathan A., Fletcher, Courtney V., Podany, Anthony T.
Published in Scientific reports (26.02.2018)
Published in Scientific reports (26.02.2018)
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Journal Article
Development, validation and utilization of a highly sensitive LC-MS/MS method for quantification of levonorgestrel released from a subdermal implant in human plasma
Cirrincione, Lauren R., Penchala, Sujan Dilly, Scarsi, Kimberly K., Podany, Anthony T., Winchester, Lee C., Back, David J., Khoo, Saye H., Fletcher, Courtney V., Siccardi, Marco, Else, Laura J.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.05.2018)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.05.2018)
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Journal Article
Quantification of Cell-Associated Atazanavir, Darunavir, Lopinavir, Ritonavir, and Efavirenz Concentrations in Human Mononuclear Cell Extracts
PODANY, Anthony T, WINCHESTER, Lee C, ROBBINS, Brian L, FLETCHER, Courtney V
Published in Antimicrobial agents and chemotherapy (01.05.2014)
Published in Antimicrobial agents and chemotherapy (01.05.2014)
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Journal Article
Impact of efavirenz pharmacokinetics and pharmacogenomics on neuropsychological performance in older HIV-infected patients
Sandkovsky, Uriel, Podany, Anthony T, Fletcher, Courtney V, Owen, Andrew, Felton-Coleman, Angela, Winchester, Lee C, Robertson, Kevin, Swindells, Susan
Published in Journal of antimicrobial chemotherapy (01.01.2017)
Published in Journal of antimicrobial chemotherapy (01.01.2017)
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Journal Article
Determination of the rifamycin antibiotics rifabutin, rifampin, rifapentine and their major metabolites in human plasma via simultaneous extraction coupled with LC/MS/MS
Winchester, Lee C., Podany, Anthony T., Baldwin, Joshua S., Robbins, Brian L., Fletcher, Courtney V.
Published in Journal of pharmaceutical and biomedical analysis (01.02.2015)
Published in Journal of pharmaceutical and biomedical analysis (01.02.2015)
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Journal Article
The anti-HIV drug abacavir stimulates β-catenin activity in osteoblast lineage cells
Olali, Arnold Z, Wallace, Jennillee, Gonzalez, Hemil, Carpenter, Kelsey A, Patel, Niyati, Winchester, Lee C, Podany, Anthony T, Venkatesh, Ishwarya, Narasipura, Srinivas D, Al-Harthi, Lena, Ross, Ryan D
Published in JBMR plus (01.05.2024)
Published in JBMR plus (01.05.2024)
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Journal Article
Enhancing antiretroviral drug penetration into lymph nodes through intramuscular and subcutaneous routes of administration in BALB/c mice
Dyavar, Shetty Ravi, Kumar, Sushil, Gautam, Nagsen, Podany, Anthony T., Winchester, Lee C., Weinhold, Jonathan A., Mykris, Timothy M., Campbell, Kayla M., Nallasamy, Palanisamy, Alnouti, Yazen, Fletcher, Courtney V.
Published in Journal of Virus Eradication (01.12.2019)
Published in Journal of Virus Eradication (01.12.2019)
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Journal Article