Kidney-on-a-Chip Technology for Drug-Induced Nephrotoxicity Screening
Wilmer, Martijn J, Ng, Chee Ping, Lanz, Henriëtte L, Vulto, Paul, Suter-Dick, Laura, Masereeuw, Rosalinde
Published in Trends in biotechnology (Regular ed.) (01.02.2016)
Published in Trends in biotechnology (Regular ed.) (01.02.2016)
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Journal Article
Flow stimulates drug transport in a human kidney proximal tubule-on-a-chip independent of primary cilia
Vriend, Jelle, Peters, Janny G.P., Nieskens, Tom T.G., Škovroňová, Renata, Blaimschein, Nina, Schmidts, Miriam, Roepman, Ronald, Schirris, Tom J.J., Russel, Frans G.M., Masereeuw, Rosalinde, Wilmer, Martijn J.
Published in Biochimica et biophysica acta. General subjects (01.01.2020)
Published in Biochimica et biophysica acta. General subjects (01.01.2020)
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Journal Article
The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development
Keuper-Navis, Marit, Walles, Markus, Poller, Birk, Myszczyszyn, Adam, van der Made, Thomas K., Donkers, Joanne, Eslami Amirabadi, Hossein, Wilmer, Martijn J., Aan, Saskia, Spee, Bart, Masereeuw, Rosalinde, van de Steeg, Evita
Published in Pharmacological research (01.09.2023)
Published in Pharmacological research (01.09.2023)
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Journal Article
The pathogenesis of cystinosis: mechanisms beyond cystine accumulation
Wilmer, Martijn J, Emma, Francesco, Levtchenko, Elena N
Published in American journal of physiology. Renal physiology (01.11.2010)
Published in American journal of physiology. Renal physiology (01.11.2010)
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Journal Article
Optimized metabolomic approach to identify uremic solutes in plasma of stage 3-4 chronic kidney disease patients
Mutsaers, Henricus A M, Engelke, Udo F H, Wilmer, Martijn J G, Wetzels, Jack F M, Wevers, Ron A, van den Heuvel, Lambertus P, Hoenderop, Joost G, Masereeuw, Rosalinde
Published in PloS one (02.08.2013)
Published in PloS one (02.08.2013)
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Journal Article
Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients
Gorvin, Caroline M., Wilmer, Martijn J., Piret, Sian E., Harding, Brian, van den Heuvel, Lambertus P., Wrong, Oliver, Jat, Parmjit S., Lippiat, Jonathan D., Levtchenko, Elena N., Thakker, Rajesh V.
Published in Proceedings of the National Academy of Sciences - PNAS (23.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (23.04.2013)
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Journal Article
Organic anion transporters 1 and 3 influence cellular energy metabolism in renal proximal tubule cells
Vriend, Jelle, Hoogstraten, Charlotte A., Venrooij, Kevin R., van den Berge, Bartholomeus T., Govers, Larissa P., van Rooij, Arno, Huigen, Marleen C.D.G., Schirris, Tom J.J., Russel, Frans G.M., Masereeuw, Rosalinde, Wilmer, Martijn J.
Published in Biological chemistry (25.09.2019)
Published in Biological chemistry (25.09.2019)
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Journal Article
Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application
Mihajlovic, Milos, van den Heuvel, Lambertus P, Hoenderop, Joost G, Jansen, Jitske, Wilmer, Martijn J, Westheim, Annemarie J F, Allebes, Wil A, Stamatialis, Dimitrios, Hilbrands, Luuk B, Masereeuw, Rosalinde
Published in Scientific reports (02.08.2017)
Published in Scientific reports (02.08.2017)
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Journal Article
Therapy with 2′-O-Me Phosphorothioate Antisense Oligonucleotides Causes Reversible Proteinuria by Inhibiting Renal Protein Reabsorption
Janssen, Manoe J., Nieskens, Tom T.G., Steevels, Tessa A.M., Caetano-Pinto, Pedro, den Braanker, Dirk, Mulder, Melissa, Ponstein, Yolanda, Jones, Shaun, Masereeuw, Rosalinde, den Besten, Cathaline, Wilmer, Martijn J.
Published in Molecular therapy. Nucleic acids (06.12.2019)
Published in Molecular therapy. Nucleic acids (06.12.2019)
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Journal Article
Proximal tubular efflux transporters involved in renal excretion of p-cresyl sulfate and p-cresyl glucuronide: Implications for chronic kidney disease pathophysiology
Mutsaers, Henricus A.M., Caetano-Pinto, Pedro, Seegers, Andries E.M., Dankers, Anita C.A., van den Broek, Petra H.H., Wetzels, Jack F.M., van den Brand, Jan A.J.G., van den Heuvel, Lambertus P., Hoenderop, Joost G., Wilmer, Martijn J.G., Masereeuw, Rosalinde
Published in Toxicology in vitro (01.10.2015)
Published in Toxicology in vitro (01.10.2015)
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Journal Article
Mesenchymal stem cell-conditioned medium accelerates regeneration of human renal proximal tubule epithelial cells after gentamicin toxicity
Moghadasali, Reza, Mutsaers, Henricus A.M., Azarnia, Mahnaz, Aghdami, Nasser, Baharvand, Hossein, Torensma, Ruurd, Wilmer, Martijn J.G., Masereeuw, Rosalinde
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.07.2013)
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.07.2013)
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Journal Article
Identification and subcellular localization of a new cystinosin isoform
Taranta, Anna, Petrini, Stefania, Palma, Alessia, Mannucci, Liliana, Wilmer, Martijn J, De Luca, Veronica, Diomedi-Camassei, Francesca, Corallini, Serena, Bellomo, Francesco, van den Heuvel, Lambert P, Levtchenko, Elena N, Emma, Francesco
Published in American journal of physiology. Renal physiology (01.05.2008)
Published in American journal of physiology. Renal physiology (01.05.2008)
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Journal Article
Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies
Vormann, Marianne K., Vriend, Jelle, Lanz, Henriëtte L., Gijzen, Linda, van den Heuvel, Angelique, Hutter, Simon, Joore, Jos, Trietsch, Sebastiaan J., Stuut, Christiaan, Nieskens, Tom T.G., Peters, Janny G.P., Ramp, Daniela, Caj, Michaela, Russel, Frans G.M., Jacobsen, Björn, Roth, Adrian, Lu, Shuyan, Polli, Joseph W., Naidoo, Anita A., Vulto, Paul, Masereeuw, Rosalinde, Wilmer, Martijn J., Suter-Dick, Laura
Published in Journal of pharmaceutical sciences (01.04.2021)
Published in Journal of pharmaceutical sciences (01.04.2021)
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Journal Article
Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip
Vriend, Jelle, Nieskens, Tom T. G., Vormann, Marianne K., van den Berge, Bartholomeus T., van den Heuvel, Angelique, Russel, Frans G. M., Suter-Dick, Laura, Lanz, Henriëtte L., Vulto, Paul, Masereeuw, Rosalinde, Wilmer, Martijn J.
Published in The AAPS journal (01.09.2018)
Published in The AAPS journal (01.09.2018)
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Journal Article
A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity
Nieskens, Tom T. G., Peters, Janny G. P., Schreurs, Marieke J., Smits, Niels, Woestenenk, Rob, Jansen, Katja, van der Made, Thom K., Röring, Melanie, Hilgendorf, Constanze, Wilmer, Martijn J, Masereeuw, Rosalinde
Published in The AAPS journal (01.03.2016)
Published in The AAPS journal (01.03.2016)
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Journal Article
Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity
Nieskens, Tom T G, Peters, Janny G P, Dabaghie, Dina, Korte, Daphne, Jansen, Katja, Van Asbeck, Alexander H, Tavraz, Neslihan N, Friedrich, Thomas, Russel, Frans G M, Masereeuw, Rosalinde, Wilmer, Martijn J
Published in Drug metabolism and disposition (01.05.2018)
Published in Drug metabolism and disposition (01.05.2018)
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Journal Article
A novel multi-parametric high content screening assay in ciPTEC-OAT1 to predict drug-induced nephrotoxicity during drug discovery
Sjögren, Anna-Karin, Breitholtz, Katarina, Ahlberg, Ernst, Milton, Lucas, Forsgard, Malin, Persson, Mikael, Stahl, Simone H., Wilmer, Martijn J., Hornberg, Jorrit J.
Published in Archives of toxicology (01.10.2018)
Published in Archives of toxicology (01.10.2018)
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Journal Article
FXYD2 and Na,K-ATPase Expression in Isolated Human Proximal Tubular Cells: Disturbed Upregulation on Renal Hypomagnesemia
Cairo, Edinio R, Swarts, Herman G. P, Wilmer, Martijn J. G, Willems, Peter H. G. M, Levtchenko, Elena N, De Pont, Jan Joep H. H. M, Koenderink, Jan B
Published in The Journal of membrane biology (01.10.2009)
Published in The Journal of membrane biology (01.10.2009)
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