NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma
Jones, Martin R, Williamson, Laura M, Topham, James T, Lee, Michael K C, Goytain, Angela, Ho, Julie, Denroche, Robert E, Jang, GunHo, Pleasance, Erin, Shen, Yaoquing, Karasinska, Joanna M, McGhie, John P, Gill, Sharlene, Lim, Howard J, Moore, Malcolm J, Wong, Hui-Li, Ng, Tony, Yip, Stephen, Zhang, Wei, Sadeghi, Sara, Reisle, Carolyn, Mungall, Andrew J, Mungall, Karen L, Moore, Richard A, Ma, Yussanne, Knox, Jennifer J, Gallinger, Steven, Laskin, Janessa, Marra, Marco A, Schaeffer, David F, Jones, Steven J M, Renouf, Daniel J
Published in Clinical cancer research (01.08.2019)
Published in Clinical cancer research (01.08.2019)
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Diagnostic and Therapeutic Implications of a FUS::TFCP2 Fusion and ALK Activation in a Metastatic Rhabdomyosarcoma
Csizmok, Veronika, Grisdale, Cameron J., Williamson, Laura M., Lim, Howard J., Lee, Lawrence, Renouf, Daniel J., Jones, Steven J. M., Marra, Marco A., Laskin, Janessa, Smrke, Alannah
Published in Genes chromosomes & cancer (01.09.2024)
Published in Genes chromosomes & cancer (01.09.2024)
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Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma
Topham, James T., Tsang, Erica S., Karasinska, Joanna M., Metcalfe, Andrew, Ali, Hassan, Kalloger, Steve E., Csizmok, Veronika, Williamson, Laura M., Titmuss, Emma, Nielsen, Karina, Negri, Gian Luca, Spencer Miko, Sandra E., Jang, Gun Ho, Denroche, Robert E., Wong, Hui-li, O’Kane, Grainne M., Moore, Richard A., Mungall, Andrew J., Loree, Jonathan M., Notta, Faiyaz, Wilson, Julie M., Bathe, Oliver F., Tang, Patricia A., Goodwin, Rachel, Morin, Gregg B., Knox, Jennifer J., Gallinger, Steven, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.
Published in Nature communications (08.10.2022)
Published in Nature communications (08.10.2022)
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Subtype-Discordant Pancreatic Ductal Adenocarcinoma Tumors Show Intermediate Clinical and Molecular Characteristics
Topham, James T, Karasinska, Joanna M, Lee, Michael K C, Csizmok, Veronika, Williamson, Laura M, Jang, Gun Ho, Denroche, Robert E, Tsang, Erica S, Kalloger, Steve E, Wong, Hui-Li, O'Kane, Grainne M, Moore, Richard A, Mungall, Andrew J, Notta, Faiyaz, Loree, Jonathan M, Wilson, Julie M, Bathe, Oliver, Tang, Patricia A, Goodwin, Rachel, Knox, Jennifer J, Gallinger, Steven, Laskin, Janessa, Marra, Marco A, Jones, Steven J M, Renouf, Daniel J, Schaeffer, David F
Published in Clinical cancer research (01.01.2021)
Published in Clinical cancer research (01.01.2021)
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Whole genome and transcriptome integrated analyses guide clinical care of pediatric poor prognosis cancers
Deyell, Rebecca J., Shen, Yaoqing, Titmuss, Emma, Dixon, Katherine, Williamson, Laura M., Pleasance, Erin, Nelson, Jessica M. T., Abbasi, Sanna, Krzywinski, Martin, Armstrong, Linlea, Bonakdar, Melika, Ch’ng, Carolyn, Chuah, Eric, Dunham, Chris, Fok, Alexandra, Jones, Martin, Lee, Anna F., Ma, Yussanne, Moore, Richard A., Mungall, Andrew J., Mungall, Karen L., Rogers, Paul C., Schrader, Kasmintan A., Virani, Alice, Wee, Kathleen, Young, Sean S., Zhao, Yongjun, Jones, Steven J. M., Laskin, Janessa, Marra, Marco A., Rassekh, Shahrad R.
Published in Nature communications (16.05.2024)
Published in Nature communications (16.05.2024)
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A platform for oncogenomic reporting and interpretation
Reisle, Caralyn, Williamson, Laura M., Pleasance, Erin, Davies, Anna, Pellegrini, Brayden, Bleile, Dustin W., Mungall, Karen L., Chuah, Eric, Jones, Martin R., Ma, Yussanne, Lewis, Eleanor, Beckie, Isaac, Pham, David, Matiello Pletz, Raphael, Muhammadzadeh, Amir, Pierce, Brandon M., Li, Jacky, Stevenson, Ross, Wong, Hansen, Bailey, Lance, Reisle, Abbey, Douglas, Matthew, Bonakdar, Melika, Nelson, Jessica M. T., Grisdale, Cameron J., Krzywinski, Martin, Fisic, Ana, Mitchell, Teresa, Renouf, Daniel J., Yip, Stephen, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M.
Published in Nature communications (09.02.2022)
Published in Nature communications (09.02.2022)
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Exploration of Germline Correlates and Risk of Immune-Related Adverse Events in Advanced Cancer Patients Treated with Immune Checkpoint Inhibitors
Titmuss, Emma, Yu, Irene S, Pleasance, Erin D, Williamson, Laura M, Mungall, Karen, Mungall, Andrew J, Renouf, Daniel J, Moore, Richard, Jones, Steven J M, Marra, Marco A, Laskin, Janessa J, Savage, Kerry J
Published in Current oncology (Toronto) (01.04.2024)
Published in Current oncology (Toronto) (01.04.2024)
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TMBur: a distributable tumor mutation burden approach for whole genome sequencing
Titmuss, Emma, Corbett, Richard D, Davidson, Scott, Abbasi, Sanna, Williamson, Laura M, Pleasance, Erin D, Shlien, Adam, Renouf, Daniel J, Jones, Steven J. M, Laskin, Janessa, Marra, Marco A
Published in BMC medical genomics (07.09.2022)
Published in BMC medical genomics (07.09.2022)
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Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration
Tsang, Erica S., Csizmok, Veronika, Williamson, Laura M., Pleasance, Erin, Topham, James T., Karasinska, Joanna M., Titmuss, Emma, Schrader, Intan, Yip, Stephen, Tessier-Cloutier, Basile, Mungall, Karen, Ng, Tony, Sun, Sophie, Lim, Howard J., Loree, Jonathan M., Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.
Published in NPJ precision oncology (24.03.2023)
Published in NPJ precision oncology (24.03.2023)
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Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury
Williamson, Laura M., Rive, Craig M., Di Francesco, Daniela, Titmuss, Emma, Chun, Hye-Jung E., Brown, Scott D., Milne, Katy, Pleasance, Erin, Lee, Anna F., Yip, Stephen, Rosenbaum, Daniel G., Hasselblatt, Martin, Johann, Pascal D., Kool, Marcel, Harvey, Melissa, Dix, David, Renouf, Daniel J., Holt, Robert A., Nelson, Brad H., Hirst, Martin, Jones, Steven J. M., Laskin, Janessa, Rassekh, Shahrad R., Deyell, Rebecca J., Marra, Marco A.
Published in NPJ precision oncology (20.12.2021)
Published in NPJ precision oncology (20.12.2021)
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Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers
Romero, Joan Miguel, Titmuss, Emma, Wang, Yifan, Vafiadis, James, Pacis, Alain, Jang, Gun Ho, Zhang, Amy, Golesworthy, Bryn, Lenko, Tatiana, Williamson, Laura M., Grünwald, Barbara, O’Kane, Grainne M., Jones, Steven J. M., Marra, Marco. A., Wilson, Julie M., Gallinger, Steven, Laskin, Janessa, Zogopoulos, George
Published in NPJ precision oncology (09.08.2023)
Published in NPJ precision oncology (09.08.2023)
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Chemical Genetics of Zipper-interacting Protein Kinase Reveal Myosin Light Chain as a Bona Fide Substrate in Permeabilized Arterial Smooth Muscle
Moffat, Lori D., Brown, Shannon B.A., Grassie, Michael E., Ulke-Lemée, Annegret, Williamson, Laura M., Walsh, Michael P., MacDonald, Justin A.
Published in The Journal of biological chemistry (21.10.2011)
Published in The Journal of biological chemistry (21.10.2011)
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Genomic characterization of a well-differentiated grade 3 pancreatic neuroendocrine tumor
Williamson, Laura M, Steel, Michael, Grewal, Jasleen K, Thibodeau, My Lihn, Zhao, Eric Y, Loree, Jonathan M, Yang, Kevin C, Gorski, Sharon M, Mungall, Andrew J, Mungall, Karen L, Moore, Richard A, Marra, Marco A, Laskin, Janessa, Renouf, Daniel J, Schaeffer, David F, Jones, Steven J M
Published in Cold Spring Harbor molecular case studies (01.06.2019)
Published in Cold Spring Harbor molecular case studies (01.06.2019)
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Altered Gene Expression along the Glycolysis-Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic Cancer
Karasinska, Joanna M, Topham, James T, Kalloger, Steve E, Jang, Gun Ho, Denroche, Robert E, Culibrk, Luka, Williamson, Laura M, Wong, Hui-Li, Lee, Michael K C, O'Kane, Grainne M, Moore, Richard A, Mungall, Andrew J, Moore, Malcolm J, Warren, Cassia, Metcalfe, Andrew, Notta, Faiyaz, Knox, Jennifer J, Gallinger, Steven, Laskin, Janessa, Marra, Marco A, Jones, Steven J M, Renouf, Daniel J, Schaeffer, David F
Published in Clinical cancer research (01.01.2020)
Published in Clinical cancer research (01.01.2020)
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Genome and Transcriptome Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors
Pender, Alexandra, Titmuss, Emma, Pleasance, Erin D, Fan, Kevin Y, Pearson, Hillary, Brown, Scott D, Grisdale, Cameron J, Topham, James T, Shen, Yaoqing, Bonakdar, Melika, Taylor, Gregory A, Williamson, Laura M, Mungall, Karen L, Chuah, Eric, Mungall, Andrew J, Moore, Richard A, Lavoie, Jean-Michel, Yip, Stephen, Lim, Howard, Renouf, Daniel J, Sun, Sophie, Holt, Robert A, Jones, Steven J M, Marra, Marco A, Laskin, Janessa
Published in Clinical cancer research (01.01.2021)
Published in Clinical cancer research (01.01.2021)
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Redox-Dependent Metastability of the Nitrogenase P‑Cluster
Rutledge, Hannah L, Rittle, Jonathan, Williamson, Laura M, Xu, Wanqing A, Gagnon, Derek M, Tezcan, F. Akif
Published in Journal of the American Chemical Society (26.06.2019)
Published in Journal of the American Chemical Society (26.06.2019)
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Enhancing clinical genomic accuracy with panelGC: a novel metric and tool for quantifying and monitoring GC biases in hybridization capture panel sequencing
Cheng, Xuanjin, Goktas, Murathan T, Williamson, Laura M, Krzywinski, Martin, Mulder, David T, Swanson, Lucas, Slind, Jill, Sihvonen, Jelena, Chow, Cynthia R, Carr, Amy, Bosdet, Ian, Tucker, Tracy, Young, Sean, Moore, Richard, Mungall, Karen L, Yip, Stephen, Jones, Steven J M
Published in Briefings in bioinformatics (25.07.2024)
Published in Briefings in bioinformatics (25.07.2024)
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Uncovering Clinically Relevant Gene Fusions with Integrated Genomic and Transcriptomic Profiling of Metastatic Cancers
Tsang, Erica S, Grisdale, Cameron J, Pleasance, Erin, Topham, James T, Mungall, Karen, Reisle, Caralyn, Choo, Caleb, Carreira, Marcus, Bowlby, Reanne, Karasinska, Joanna M, MacMillan, Daniel, Williamson, Laura M, Chuah, Eric, Moore, Richard A, Mungall, Andrew J, Zhao, Yongjun, Tessier-Cloutier, Basile, Ng, Tony, Sun, Sophie, Lim, Howard J, Schaeffer, David F, Renouf, Daniel J, Yip, Stephen, Laskin, Janessa, Marra, Marco A, Jones, Steven J M, Loree, Jonathan M
Published in Clinical cancer research (15.01.2021)
Published in Clinical cancer research (15.01.2021)
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