Polymer-Fullerene Bulk-Heterojunction Solar Cells
Brabec, Christoph J., Gowrisanker, Srinivas, Halls, Jonathan J. M., Laird, Darin, Jia, Shijun, Williams, Shawn P.
Published in Advanced materials (Weinheim) (08.09.2010)
Published in Advanced materials (Weinheim) (08.09.2010)
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Classification of crystallization outcomes using deep convolutional neural networks
Bruno, Andrew E, Charbonneau, Patrick, Newman, Janet, Snell, Edward H, So, David R, Vanhoucke, Vincent, Watkins, Christopher J, Williams, Shawn, Wilson, Julie
Published in PloS one (20.06.2018)
Published in PloS one (20.06.2018)
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A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site
Hardwicke, Mary Ann, Rendina, Alan R, Williams, Shawn P, Moore, Michael L, Wang, Liping, Krueger, Julie A, Plant, Ramona N, Totoritis, Rachel D, Zhang, Guofeng, Briand, Jacques, Burkhart, William A, Brown, Kristin K, Parrish, Cynthia A
Published in Nature chemical biology (01.09.2014)
Published in Nature chemical biology (01.09.2014)
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Design of N‑Benzoxaborole Benzofuran GSK8175Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor
Chong, Pek Y, Shotwell, J. Brad, Miller, John, Price, Daniel J, Maynard, Andy, Voitenleitner, Christian, Mathis, Amanda, Williams, Shawn, Pouliot, Jeffrey J, Creech, Katrina, Wang, Feng, Fang, Jing, Zhang, Huichang, Tai, Vincent W.-F, Turner, Elizabeth, Kahler, Kirsten M, Crosby, Renae, Peat, Andrew J
Published in Journal of medicinal chemistry (11.04.2019)
Published in Journal of medicinal chemistry (11.04.2019)
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Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement
Barton, Linda S., Callahan, James F., Cantizani, Juan, Concha, Nestor O., Cotillo Torrejon, Ignacio, Goodwin, Nicole C., Joshi-Pangu, Amruta, Kiesow, Terry J., McAtee, Jeff J., Mellinger, Mark, Nixon, Christopher J., Padrón-Barthe, Laura, Patterson, Jaclyn R., Pearson, Neil D., Pouliot, Jeffrey J., Rendina, Alan R., Buitrago Santanilla, Alexander, Schneck, Jessica L., Sanz, Olalla, Thalji, Reema K., Ward, Paris, Williams, Shawn P., King, Bryan W.
Published in Bioorganic & medicinal chemistry (15.02.2024)
Published in Bioorganic & medicinal chemistry (15.02.2024)
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Journal Article
An orally available, brain-penetrant CAMKK2 inhibitor reduces food intake in rodent model
Price, Daniel J., Drewry, David H., Schaller, Lee T., Thompson, Brian D., Reid, Paul R., Maloney, Patrick R., Liang, Xi, Banker, Periette, Buckholz, Richard G., Selley, Paula K., McDonald, Octerloney B., Smith, Jeffery L., Shearer, Todd W., Cox, Richard F., Williams, Shawn P., Reid, Robert A., Tacconi, Stefano, Faggioni, Federico, Piubelli, Chiara, Sartori, Ilaria, Tessari, Michela, Wang, Tony Y.
Published in Bioorganic & medicinal chemistry letters (01.06.2018)
Published in Bioorganic & medicinal chemistry letters (01.06.2018)
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Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction
Ramanjulu, Joshi M, Williams, Shawn P, Lakdawala, Ami S, DeMartino, Michael P, Lan, Yunfeng, Marquis, Robert W
Published in ACS medicinal chemistry letters (09.09.2021)
Published in ACS medicinal chemistry letters (09.09.2021)
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Small Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2)
Whitby, Richard J, Stec, Jozef, Blind, Raymond D, Dixon, Sally, Leesnitzer, Lisa M, Orband-Miller, Lisa A, Williams, Shawn P, Willson, Timothy M, Xu, Robert, Zuercher, William J, Cai, Fang, Ingraham, Holly A
Published in Journal of medicinal chemistry (14.04.2011)
Published in Journal of medicinal chemistry (14.04.2011)
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A Structural and in Vitro Characterization of Asoprisnil: A Selective Progesterone Receptor Modulator
Madauss, Kevin P, Grygielko, Eugene T, Deng, Su-Jun, Sulpizio, Anthony C, Stanley, Thomas B, Wu, Charlene, Short, Steve A, Thompson, Scott K, Stewart, Eugene L, Laping, Nicholas J, Williams, Shawn P, Bray, Jeffrey D
Published in Molecular endocrinology (Baltimore, Md.) (01.05.2007)
Published in Molecular endocrinology (Baltimore, Md.) (01.05.2007)
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Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064
Akwabi-Ameyaw, Adwoa, Bass, Jonathan Y., Caldwell, Richard D., Caravella, Justin A., Chen, Lihong, Creech, Katrina L., Deaton, David N., Jones, Stacey A., Kaldor, Istvan, Liu, Yaping, Madauss, Kevin P., Marr, Harry B., McFadyen, Robert B., Miller, Aaron B., III, Frank Navas, Parks, Derek J., Spearing, Paul K., Todd, Dan, Williams, Shawn P., Wisely, G. Bruce
Published in Bioorganic & medicinal chemistry (01.08.2008)
Published in Bioorganic & medicinal chemistry (01.08.2008)
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Journal Article
The Human Nuclear Xenobiotic Receptor PXR: Structural Determinants of Directed Promiscuity
Watkins, Ryan E., Wisely, G. Bruce, Moore, Linda B., Collins, Jon L., Lambert, Millard H., Williams, Shawn P., Willson, Timothy M., Kliewer, Steven A., Redinbo, Matthew R.
Published in Science (American Association for the Advancement of Science) (22.06.2001)
Published in Science (American Association for the Advancement of Science) (22.06.2001)
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Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction
Phelan, Caroline A, Gampe, Robert T, Lambert, Millard H, Parks, Derek J, Montana, Valerie, Bynum, Jane, Broderick, Timothy M, Hu, Xiao, Williams, Shawn P, Nolte, Robert T, Lazar, Mitchell A
Published in Nature structural & molecular biology (01.07.2010)
Published in Nature structural & molecular biology (01.07.2010)
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Journal Article
The Drosophila Nuclear Receptor E75 Contains Heme and Is Gas Responsive
Reinking, Jeff, Lam, Mandy M.S., Pardee, Keith, Sampson, Heidi M., Liu, Suya, Yang, Ping, Williams, Shawn, White, Wendy, Lajoie, Gilles, Edwards, Aled, Krause, Henry M.
Published in Cell (29.07.2005)
Published in Cell (29.07.2005)
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Structural Analyses Reveal Phosphatidyl Inositols as Ligands for the NR5 Orphan Receptors SF-1 and LRH- 1
Krylova, Irina N., Sablin, Elena P., Moore, Jamie, Xu, Robert X., Waitt, Gregory M., MacKay, J. Andrew, Juzumiene, Dalia, Bynum, Jane M., Madauss, Kevin, Montana, Valerie, Lebedeva, Lioudmila, Suzawa, Miyuki, Williams, Jon D., Williams, Shawn P., Guy, Rodney K., Thornton, Joseph W., Fletterick, Robert J., Willson, Timothy M., Ingraham, Holly A.
Published in Cell (11.02.2005)
Published in Cell (11.02.2005)
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Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor
Biggadike, Keith, Bledsoe, Randy K, Coe, Diane M, Cooper, Tony W.J, House, David, Iannone, Marie A, Macdonald, Simon J.F, Madauss, Kevin P, McLay, Iain M, Shipley, Tracy J, Taylor, Simon J, Tran, Thuy B, Uings, Iain J, Weller, Victoria, Williams, Shawn P
Published in Proceedings of the National Academy of Sciences - PNAS (27.10.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (27.10.2009)
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Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene
Bass, Jonathan Y., Caravella, Justin A., Chen, Lihong, Creech, Katrina L., Deaton, David N., Madauss, Kevin P., Marr, Harry B., McFadyen, Robert B., Miller, Aaron B., Mills, Wendy Y., Navas, Frank, Parks, Derek J., Smalley, Terrence L., Spearing, Paul K., Todd, Dan, Williams, Shawn P., Wisely, G. Bruce
Published in Bioorganic & medicinal chemistry letters (15.02.2011)
Published in Bioorganic & medicinal chemistry letters (15.02.2011)
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