Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals
Quirós, Pedro M, Prado, Miguel A, Zamboni, Nicola, D'Amico, Davide, Williams, Robert W, Finley, Daniel, Gygi, Steven P, Auwerx, Johan
Published in The Journal of cell biology (03.07.2017)
Published in The Journal of cell biology (03.07.2017)
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Journal Article
Ethanol-Induced Behavioral Sensitization Alters the Synaptic Transcriptome and Exon Utilization in DBA/2J Mice
O'Brien, Megan A, Weston, Rory M, Sheth, Nihar U, Bradley, Steven, Bigbee, John, Pandey, Ashutosh, Williams, Robert W, Wolstenholme, Jennifer T, Miles, Michael F
Published in Frontiers in genetics (24.09.2018)
Published in Frontiers in genetics (24.09.2018)
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Journal Article
PONDR-FIT: A meta-predictor of intrinsically disordered amino acids
Xue, Bin, Dunbrack, Roland L., Williams, Robert W., Dunker, A. Keith, Uversky, Vladimir N.
Published in Biochimica et biophysica acta (01.04.2010)
Published in Biochimica et biophysica acta (01.04.2010)
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Journal Article
Systems Genetics of Metabolism: The Use of the BXD Murine Reference Panel for Multiscalar Integration of Traits
Andreux, Pénélope A., Williams, Evan G., Koutnikova, Hana, Houtkooper, Riekelt H., Champy, Marie-France, Henry, Hugues, Schoonjans, Kristina, Williams, Robert W., Auwerx, Johan
Published in Cell (14.09.2012)
Published in Cell (14.09.2012)
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Journal Article
Functionally enigmatic genes: a case study of the brain ignorome
Pandey, Ashutosh K, Lu, Lu, Wang, Xusheng, Homayouni, Ramin, Williams, Robert W
Published in PloS one (11.02.2014)
Published in PloS one (11.02.2014)
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Journal Article
Reduced oxidative capacity in macrophages results in systemic insulin resistance
Jung, Saet-Byel, Choi, Min Jeong, Ryu, Dongryeol, Yi, Hyon-Seung, Lee, Seong Eun, Chang, Joon Young, Chung, Hyo Kyun, Kim, Yong Kyung, Kang, Seul Gi, Lee, Ju Hee, Kim, Koon Soon, Kim, Hyun Jin, Kim, Cuk-Seong, Lee, Chul-Ho, Williams, Robert W., Kim, Hail, Lee, Heung Kyu, Auwerx, Johan, Shong, Minho
Published in Nature communications (19.04.2018)
Published in Nature communications (19.04.2018)
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Journal Article
Metabolic Stress Modulates Alzheimer’s β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons
Wang, Ruishan, Li, Jing Jing, Diao, Shiyong, Kwak, Young-Don, Liu, Li, Zhi, Lianteng, Büeler, Hansruedi, Bhat, Narayan R., Williams, Robert W., Park, Edwards A., Liao, Francesca-Fang
Published in Cell metabolism (07.05.2013)
Published in Cell metabolism (07.05.2013)
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Journal Article
Reproducibility and replicability of rodent phenotyping in preclinical studies
Kafkafi, Neri, Agassi, Joseph, Chesler, Elissa J., Crabbe, John C., Crusio, Wim E., Eilam, David, Gerlai, Robert, Golani, Ilan, Gomez-Marin, Alex, Heller, Ruth, Iraqi, Fuad, Jaljuli, Iman, Karp, Natasha A., Morgan, Hugh, Nicholson, George, Pfaff, Donald W., Richter, S. Helene, Stark, Philip B., Stiedl, Oliver, Stodden, Victoria, Tarantino, Lisa M., Tucci, Valter, Valdar, William, Williams, Robert W., Würbel, Hanno, Benjamini, Yoav
Published in Neuroscience and biobehavioral reviews (01.04.2018)
Published in Neuroscience and biobehavioral reviews (01.04.2018)
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Journal Article
Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose
Senko, Anna N, Overall, Rupert W, Silhavy, Jan, Mlejnek, Petr, Malínská, Hana, Hüttl, Martina, Marková, Irena, Fabel, Klaus S, Lu, Lu, Stuchlik, Ales, Williams, Robert W, Pravenec, Michal, Kempermann, Gerd
Published in PLoS genetics (04.04.2022)
Published in PLoS genetics (04.04.2022)
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Journal Article
Variability and heritability of mouse brain structure: Microscopic MRI atlases and connectomes for diverse strains
Wang, Nian, Anderson, Robert J., Ashbrook, David G., Gopalakrishnan, Vivek, Park, Youngser, Priebe, Carey E., Qi, Yi, Laoprasert, Rick, Vogelstein, Joshua T., Williams, Robert W., Johnson, G. Allan
Published in NeuroImage (Orlando, Fla.) (15.11.2020)
Published in NeuroImage (Orlando, Fla.) (15.11.2020)
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Journal Article
Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits
McKnite, Autumn M, Perez-Munoz, Maria Elisa, Lu, Lu, Williams, Evan G, Brewer, Simon, Andreux, Pénélope A, Bastiaansen, John W M, Wang, Xusheng, Kachman, Stephen D, Auwerx, Johan, Williams, Robert W, Benson, Andrew K, Peterson, Daniel A, Ciobanu, Daniel C
Published in PloS one (18.06.2012)
Published in PloS one (18.06.2012)
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Journal Article
Genetic Variation in the Social Environment Contributes to Health and Disease
Baud, Amelie, Mulligan, Megan K, Casale, Francesco Paolo, Ingels, Jesse F, Bohl, Casey J, Callebert, Jacques, Launay, Jean-Marie, Krohn, Jon, Legarra, Andres, Williams, Robert W, Stegle, Oliver
Published in PLoS genetics (01.01.2017)
Published in PLoS genetics (01.01.2017)
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Journal Article
Genetic loci and metabolic states associated with murine epigenetic aging
Mozhui, Khyobeni, Lu, Ake T, Li, Caesar Z, Haghani, Amin, Sandoval-Sierra, Jose Vladimir, Wu, Yibo, Williams, Robert W, Horvath, Steve
Published in eLife (07.04.2022)
Published in eLife (07.04.2022)
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Journal Article
Joint mouse–human phenome-wide association to test gene function and disease risk
Wang, Xusheng, Pandey, Ashutosh K., Mulligan, Megan K., Williams, Evan G., Mozhui, Khyobeni, Li, Zhengsheng, Jovaisaite, Virginija, Quarles, L. Darryl, Xiao, Zhousheng, Huang, Jinsong, Capra, John A., Chen, Zugen, Taylor, William L., Bastarache, Lisa, Niu, Xinnan, Pollard, Katherine S., Ciobanu, Daniel C., Reznik, Alexander O., Tishkov, Artem V., Zhulin, Igor B., Peng, Junmin, Nelson, Stanley F., Denny, Joshua C., Auwerx, Johan, Lu, Lu, Williams, Robert W.
Published in Nature communications (02.02.2016)
Published in Nature communications (02.02.2016)
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Journal Article
Identifying gene function and module connections by the integration of multispecies expression compendia
Li, Hao, Rukina, Daria, David, Fabrice P A, Li, Terytty Yang, Oh, Chang-Myung, Gao, Arwen W, Katsyuba, Elena, Bou Sleiman, Maroun, Komljenovic, Andrea, Huang, Qingyao, Williams, Robert W, Robinson-Rechavi, Marc, Schoonjans, Kristina, Morgenthaler, Stephan, Auwerx, Johan
Published in Genome research (01.12.2019)
Published in Genome research (01.12.2019)
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Journal Article
Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge
Elam, Marshall B, Majumdar, Gipsy, Mozhui, Khyobeni, Gerling, Ivan C, Vera, Santiago R, Fish-Trotter, Hannah, Williams, Robert W, Childress, Richard D, Raghow, Rajendra
Published in PloS one (03.08.2017)
Published in PloS one (03.08.2017)
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Journal Article
Bayesian association scan reveals loci associated with human lifespan and linked biomarkers
McDaid, Aaron F., Joshi, Peter K., Porcu, Eleonora, Komljenovic, Andrea, Li, Hao, Sorrentino, Vincenzo, Litovchenko, Maria, Bevers, Roel P. J., Rüeger, Sina, Reymond, Alexandre, Bochud, Murielle, Deplancke, Bart, Williams, Robert W., Robinson-Rechavi, Marc, Paccaud, Fred, Rousson, Valentin, Auwerx, Johan, Wilson, James F., Kutalik, Zoltán
Published in Nature communications (27.07.2017)
Published in Nature communications (27.07.2017)
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Journal Article
Identification of cyclin D1 as a major modulator of 3-nitropropionic acid-induced striatal neurodegeneration
Dietrich, Paula, Alli, Shanta, Mulligan, Megan K., Cox, Rachel, Ashbrook, David G., Williams, Robert W., Dragatsis, Ioannis
Published in Neurobiology of disease (01.01.2022)
Published in Neurobiology of disease (01.01.2022)
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Journal Article