Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research
Moullan, Norman, Mouchiroud, Laurent, Wang, Xu, Ryu, Dongryeol, Williams, Evan G., Mottis, Adrienne, Jovaisaite, Virginija, Frochaux, Michael V., Quiros, Pedro M., Deplancke, Bart, Houtkooper, Riekelt H., Auwerx, Johan
Published in Cell reports (Cambridge) (17.03.2015)
Published in Cell reports (Cambridge) (17.03.2015)
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Journal Article
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
Ryu, Dongryeol, Mouchiroud, Laurent, Andreux, Pénélope A, Katsyuba, Elena, Moullan, Norman, Nicolet-dit-Félix, Amandine A, Williams, Evan G, Jha, Pooja, Lo Sasso, Giuseppe, Huzard, Damien, Aebischer, Patrick, Sandi, Carmen, Rinsch, Chris, Auwerx, Johan
Published in Nature medicine (01.08.2016)
Published in Nature medicine (01.08.2016)
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Journal Article
Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population
Wu, Yibo, Williams, Evan G, Dubuis, Sébastien, Mottis, Adrienne, Jovaisaite, Virginija, Houten, Sander M, Argmann, Carmen A, Faridi, Pouya, Wolski, Witold, Kutalik, Zoltán, Zamboni, Nicola, Auwerx, Johan, Aebersold, Ruedi
Published in Cell (11.09.2014)
Published in Cell (11.09.2014)
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Journal Article
Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity
Merkwirth, Carsten, Jovaisaite, Virginija, Durieux, Jenni, Matilainen, Olli, Jordan, Sabine D., Quiros, Pedro M., Steffen, Kristan K., Williams, Evan G., Mouchiroud, Laurent, Tronnes, Sarah U., Murillo, Virginia, Wolff, Suzanne C., Shaw, Reuben J., Auwerx, Johan, Dillin, Andrew
Published in Cell (19.05.2016)
Published in Cell (19.05.2016)
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Journal Article
NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function
Yamamoto, Hiroyasu, Williams, Evan G., Mouchiroud, Laurent, Cantó, Carles, Fan, Weiwei, Downes, Michael, Héligon, Christophe, Barish, Grant D., Desvergne, Béatrice, Evans, Ronald M., Schoonjans, Kristina, Auwerx, Johan
Published in Cell (11.11.2011)
Published in Cell (11.11.2011)
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Journal Article
Systems Genetics of Metabolism: The Use of the BXD Murine Reference Panel for Multiscalar Integration of Traits
Andreux, Pénélope A., Williams, Evan G., Koutnikova, Hana, Houtkooper, Riekelt H., Champy, Marie-France, Henry, Hugues, Schoonjans, Kristina, Williams, Robert W., Auwerx, Johan
Published in Cell (14.09.2012)
Published in Cell (14.09.2012)
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Journal Article
Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle
Pirinen, Eija, Cantó, Carles, Jo, Young Suk, Morato, Laia, Zhang, Hongbo, Menzies, Keir J., Williams, Evan G., Mouchiroud, Laurent, Moullan, Norman, Hagberg, Carolina, Li, Wei, Timmers, Silvie, Imhof, Ralph, Verbeek, Jef, Pujol, Aurora, van Loon, Barbara, Viscomi, Carlo, Zeviani, Massimo, Schrauwen, Patrick, Sauve, Anthony A., Schoonjans, Kristina, Auwerx, Johan
Published in Cell metabolism (03.06.2014)
Published in Cell metabolism (03.06.2014)
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Journal Article
Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells
Liu, Yansheng, Borel, Christelle, Li, Li, Müller, Torsten, Williams, Evan G., Germain, Pierre-Luc, Buljan, Marija, Sajic, Tatjana, Boersema, Paul J., Shao, Wenguang, Faini, Marco, Testa, Giuseppe, Beyer, Andreas, Antonarakis, Stylianos E., Aebersold, Ruedi
Published in Nature communications (31.10.2017)
Published in Nature communications (31.10.2017)
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Journal Article
A Conserved Mito-Cytosolic Translational Balance Links Two Longevity Pathways
Molenaars, Marte, Janssens, Georges E., Williams, Evan G., Jongejan, Aldo, Lan, Jiayi, Rabot, Sylvie, Joly, Fatima, Moerland, Perry D., Schomakers, Bauke V., Lezzerini, Marco, Liu, Yasmine J., McCormick, Mark A., Kennedy, Brian K., van Weeghel, Michel, van Kampen, Antoine H.C., Aebersold, Ruedi, MacInnes, Alyson W., Houtkooper, Riekelt H.
Published in Cell metabolism (03.03.2020)
Published in Cell metabolism (03.03.2020)
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Journal Article
Regulation of Steatohepatitis and PPARγ Signaling by Distinct AP-1 Dimers
Hasenfuss, Sebastian C., Bakiri, Latifa, Thomsen, Martin K., Williams, Evan G., Auwerx, Johan, Wagner, Erwin F.
Published in Cell metabolism (07.01.2014)
Published in Cell metabolism (07.01.2014)
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Journal Article
Diagnostics and correction of batch effects in large‐scale proteomic studies: a tutorial
Čuklina, Jelena, Lee, Chloe H, Williams, Evan G, Sajic, Tatjana, Collins, Ben C, Rodríguez Martínez, María, Sharma, Varun S, Wendt, Fabian, Goetze, Sandra, Keele, Gregory R, Wollscheid, Bernd, Aebersold, Ruedi, Pedrioli, Patrick G A
Published in Molecular systems biology (01.08.2021)
Published in Molecular systems biology (01.08.2021)
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Journal Article
Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits
McKnite, Autumn M, Perez-Munoz, Maria Elisa, Lu, Lu, Williams, Evan G, Brewer, Simon, Andreux, Pénélope A, Bastiaansen, John W M, Wang, Xusheng, Kachman, Stephen D, Auwerx, Johan, Williams, Robert W, Benson, Andrew K, Peterson, Daniel A, Ciobanu, Daniel C
Published in PloS one (18.06.2012)
Published in PloS one (18.06.2012)
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Journal Article
Joint mouse–human phenome-wide association to test gene function and disease risk
Wang, Xusheng, Pandey, Ashutosh K., Mulligan, Megan K., Williams, Evan G., Mozhui, Khyobeni, Li, Zhengsheng, Jovaisaite, Virginija, Quarles, L. Darryl, Xiao, Zhousheng, Huang, Jinsong, Capra, John A., Chen, Zugen, Taylor, William L., Bastarache, Lisa, Niu, Xinnan, Pollard, Katherine S., Ciobanu, Daniel C., Reznik, Alexander O., Tishkov, Artem V., Zhulin, Igor B., Peng, Junmin, Nelson, Stanley F., Denny, Joshua C., Auwerx, Johan, Lu, Lu, Williams, Robert W.
Published in Nature communications (02.02.2016)
Published in Nature communications (02.02.2016)
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Journal Article
Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans
van de Weijer, Tineke, Phielix, Esther, Bilet, Lena, Williams, Evan G, Ropelle, Eduardo R, Bierwagen, Alessandra, Livingstone, Roshan, Nowotny, Peter, Sparks, Lauren M, Paglialunga, Sabina, Szendroedi, Julia, Havekes, Bas, Moullan, Norman, Pirinen, Eija, Hwang, Jong-Hee, Schrauwen-Hinderling, Vera B, Hesselink, Matthijs K C, Auwerx, Johan, Roden, Michael, Schrauwen, Patrick
Published in Diabetes (New York, N.Y.) (01.04.2015)
Published in Diabetes (New York, N.Y.) (01.04.2015)
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Journal Article
Diet modulates cecum bacterial diversity and physiological phenotypes across the BXD mouse genetic reference population
Perez-Munoz, Maria Elisa, McKnite, Autumn M, Williams, Evan G, Auwerx, Johan, Williams, Robert W, Peterson, Daniel A, Ciobanu, Daniel C
Published in PloS one (21.10.2019)
Published in PloS one (21.10.2019)
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Journal Article
Similarities and Differences of Blood N-Glycoproteins in Five Solid Carcinomas at Localized Clinical Stage Analyzed by SWATH-MS
Sajic, Tatjana, Liu, Yansheng, Arvaniti, Eirini, Surinova, Silvia, Williams, Evan G., Schiess, Ralph, Hüttenhain, Ruth, Sethi, Atul, Pan, Sheng, Brentnall, Teresa A., Chen, Ru, Blattmann, Peter, Friedrich, Betty, Niméus, Emma, Malander, Susanne, Omlin, Aurelius, Gillessen, Silke, Claassen, Manfred, Aebersold, Ruedi
Published in Cell reports (Cambridge) (29.05.2018)
Published in Cell reports (Cambridge) (29.05.2018)
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Journal Article
Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI
van der Kolk, Birgitta W., Saari, Sina, Lovric, Alen, Arif, Muhammad, Alvarez, Marcus, Ko, Arthur, Miao, Zong, Sahebekhtiari, Navid, Muniandy, Maheswary, Heinonen, Sini, Oghabian, Ali, Jokinen, Riikka, Jukarainen, Sakari, Hakkarainen, Antti, Lundbom, Jesper, Kuula, Juho, Groop, Per-Henrik, Tukiainen, Taru, Lundbom, Nina, Rissanen, Aila, Kaprio, Jaakko, Williams, Evan G., Zamboni, Nicola, Mardinoglu, Adil, Pajukanta, Päivi, Pietiläinen, Kirsi H.
Published in Cell reports. Medicine (20.04.2021)
Published in Cell reports. Medicine (20.04.2021)
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