Enzyme-Mediated Site-Specific Bioconjugation of Metal Complexes to Proteins: Sortase-Mediated Coupling of Copper-64 to a Single-Chain Antibody
Paterson, Brett M., Alt, Karen, Jeffery, Charmaine M., Price, Roger I., Jagdale, Shweta, Rigby, Sheena, Williams, Charlotte C., Peter, Karlheinz, Hagemeyer, Christoph E., Donnelly, Paul S.
Published in Angewandte Chemie International Edition (10.06.2014)
Published in Angewandte Chemie International Edition (10.06.2014)
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Journal Article
Cofactor and Process Engineering for Nicotinamide Recycling and Retention in Intensified Biocatalysis
Rocha, Raquel A, North, Andrea J, Speight, Robert E, Williams, Charlotte C, Scott, Colin
Published in Catalysts (01.11.2022)
Published in Catalysts (01.11.2022)
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Journal Article
An Evaluation of Optimal PEGylation Strategies for Maximizing the Lymphatic Exposure and Antiviral Activity of Interferon after Subcutaneous Administration
Chan, Linda J, Feeney, Orlagh M, Leong, Nathania J, McLeod, Victoria M, Porter, Christopher J.H, Williams, Charlotte C, Kaminskas, Lisa M
Published in Biomacromolecules (11.09.2017)
Published in Biomacromolecules (11.09.2017)
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Journal Article
Sugar analog synthesis by in vitro biocatalytic cascade: A comparison of alternative enzyme complements for dihydroxyacetone phosphate production as a precursor to rare chiral sugar synthesis
Hartley, Carol J, French, Nigel G, Scoble, Judith A, Williams, Charlotte C, Churches, Quentin I, Frazer, Andrew R, Taylor, Matthew C, Coia, Greg, Simpson, Gregory, Turner, Nicholas J, Scott, Colin
Published in PloS one (07.11.2017)
Published in PloS one (07.11.2017)
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Journal Article
Engineering of an anti-epidermal growth factor receptor antibody to single chain format and labeling by sortase A-mediated protein ligation
Madej, Mariusz P., Coia, Gregory, Williams, Charlotte C., Caine, Joanne M., Pearce, Lesley A., Attwood, Rebecca, Bartone, Nick A., Dolezal, Olan, Nisbet, Rebecca M., Nuttall, Stewart D., Adams, Timothy E.
Published in Biotechnology and bioengineering (01.06.2012)
Published in Biotechnology and bioengineering (01.06.2012)
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Journal Article
Surfactant protein-A nanobody-conjugated liposomes loaded with methylprednisolone increase lung-targeting specificity and therapeutic effect for acute lung injury
Li, Nan, Weng, Dong, Wang, Shan-Mei, Zhang, Yuan, Chen, Shan-Shan, Yin, Zhao-Fang, Zhai, Jiali, Scoble, Judy, Williams, Charlotte C., Chen, Tao, Qiu, Hui, Wu, Qin, Zhao, Meng-Meng, Lu, Li-Qin, Mulet, Xavier, Li, Hui-Ping
Published in Drug delivery (2017)
Published in Drug delivery (2017)
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Journal Article
Determination of the structure of the catabolic N-succinylornithine transaminase (AstC) from Escherichia coli
Newman, Janet, Seabrook, Shane, Surjadi, Regina, Williams, Charlotte C, Lucent, Del, Wilding, Matthew, Scott, Colin, Peat, Thomas S
Published in PloS one (06.03.2013)
Published in PloS one (06.03.2013)
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Journal Article
Kinetic Model for the Heterogeneous Biocatalytic Reactions Using Tethered Cofactors
McDonough, Rowan, Williams, Charlotte C., Hartley, Carol J., French, Nigel, Scott, Colin, Lewis, David A.
Published in Langmuir (02.04.2024)
Published in Langmuir (02.04.2024)
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Journal Article
RAFT Polymer–Antibody Conjugation: Squaramide Ester Chemistry Leads to Conjugates with a Therapeutic Anti-EGFR Antibody with Full Retention of Activity and Increased Tumor Uptake In Vivo
Ardana, Aditya, Ghosh, Saikat, Huda, Pie, Fletcher, Nicholas L., Thurecht, Kristofer J., Williams, Charlotte C.
Published in Molecular pharmaceutics (05.06.2023)
Published in Molecular pharmaceutics (05.06.2023)
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Journal Article
Oral nanotherapeutic formulation of insulin with reduced episodes of hypoglycaemia
Hunt, Nicholas J., Lockwood, Glen P., Heffernan, Scott J., Daymond, Jarryd, Ngu, Meng, Narayanan, Ramesh K., Westwood, Lara J., Mohanty, Biswaranjan, Esser, Lars, Williams, Charlotte C., Kuncic, Zdenka, McCourt, Peter A. G., Le Couteur, David G., Cogger, Victoria C.
Published in Nature nanotechnology (01.04.2024)
Published in Nature nanotechnology (01.04.2024)
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Journal Article
Preparation of Protein–Polymer Conjugates: Copolymerisation by RAFT
Huang, Fei, Scoble, Judith A., Chiefari, John, Williams, Charlotte C.
Published in Australian journal of chemistry (01.01.2020)
Published in Australian journal of chemistry (01.01.2020)
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Journal Article
Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteins
Subasic, Christopher N., Ardana, Aditya, Chan, Linda J., Huang, Fei, Scoble, Judith A., Butcher, Neville J., Meagher, Laurence, Chiefari, John, Kaminskas, Lisa M., Williams, Charlotte C.
Published in International journal of pharmaceutics (25.10.2021)
Published in International journal of pharmaceutics (25.10.2021)
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Journal Article
Enzyme mediated incorporation of zirconium-89 or copper-64 into a fragment antibody for same day imaging of epidermal growth factor receptor
Rudd, Stacey E, Van Zuylekom, Jessica K, Raicevic, Anna, Pearce, Lesley A, Cullinane, Carleen, Williams, Charlotte C, Adams, Timothy E, Hicks, Rodney J, Donnelly, Paul S
Published in Chemical science (Cambridge) (07.07.2021)
Published in Chemical science (Cambridge) (07.07.2021)
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Journal Article
Dual Site-Specific Labeling of an Antibody Fragment through Sortase A and π‑Clamp Conjugation
Lee, Michael D, Tong, Wing Yin, Nebl, Thomas, Pearce, Lesley A, Pham, Tam M, Golbaz-Hagh, Arghavan, Puttick, Simon, Rose, Stephen, Adams, Timothy E, Williams, Charlotte C
Published in Bioconjugate chemistry (16.10.2019)
Published in Bioconjugate chemistry (16.10.2019)
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Journal Article
A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats
Kaminskas, Lisa M., Williams, Charlotte C., Leong, Nathania J., Chan, Linda J., Butcher, Neville J., Feeney, Orlagh M., Porter, Christopher J.H., Tyssen, David, Tachedjian, Gilda, Ascher, David B.
Published in European journal of pharmaceutics and biopharmaceutics (01.04.2019)
Published in European journal of pharmaceutics and biopharmaceutics (01.04.2019)
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Journal Article
Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian Cancer
He, Yaowu, Khan, Tashbib, Kryza, Thomas, Jones, Martina L, Goh, Justin B, Lyons, Nicholas J, Pearce, Lesley A, Lee, Michael D, Gough, Madeline, Rogers, Rebecca, Davies, Claire M, Gilks, C. Blake, Hodgkinson, Thomas, Lourie, Rohan, Barry, Sinead C, Perrin, Lewis C, Williams, Charlotte C, Puttick, Simon, Adams, Timothy E, Munro, Trent P, Hooper, John D, Chetty, Naven
Published in Molecular pharmaceutics (06.09.2021)
Published in Molecular pharmaceutics (06.09.2021)
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Journal Article
A chemiluminescent sandwich ELISA enhancement method using a chromium (III) coordination complex
Welch, Nicholas G., Easton, Christopher D., Scoble, Judith A., Williams, Charlotte C., Pigram, Paul J., Muir, Benjamin W.
Published in Journal of immunological methods (01.11.2016)
Published in Journal of immunological methods (01.11.2016)
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Journal Article
High-Throughput Production of Chromium(III) Complexes for Antibody Immobilization
Welch, Nicholas G, Scoble, Judith A, Easton, Christopher D, Williams, Charlotte C, Bradford, Barry J, Mamedova, Laman K, Pigram, Paul J, Muir, Benjamin W
Published in Analytical chemistry (Washington) (18.10.2016)
Published in Analytical chemistry (Washington) (18.10.2016)
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Journal Article
Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab′ Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity
Chan, Linda J, Ascher, David B, Yadav, Rajbharan, Bulitta, Jürgen B, Williams, Charlotte C, Porter, Christopher J. H, Landersdorfer, Cornelia B, Kaminskas, Lisa M
Published in Molecular pharmaceutics (04.04.2016)
Published in Molecular pharmaceutics (04.04.2016)
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