The inflammatory microenvironment and microbiome in prostate cancer development
Sfanos, Karen S., Yegnasubramanian, Srinivasan, Nelson, William G., De Marzo, Angelo M.
Published in Nature reviews. Urology (01.01.2018)
Published in Nature reviews. Urology (01.01.2018)
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Tracking the clonal origin of lethal prostate cancer
Haffner, Michael C, Mosbruger, Timothy, Esopi, David M, Fedor, Helen, Heaphy, Christopher M, Walker, David A, Adejola, Nkosi, Gürel, Meltem, Hicks, Jessica, Meeker, Alan K, Halushka, Marc K, Simons, Jonathan W, Isaacs, William B, De Marzo, Angelo M, Nelson, William G, Yegnasubramanian, Srinivasan
Published in The Journal of clinical investigation (01.11.2013)
Published in The Journal of clinical investigation (01.11.2013)
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Journal Article
Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer
Bova, G Steven, Liu, Wennuan, Laitinen, Sari, Khan, Sofia, Vihinen, Mauno, Kowalski, Jeanne, Yu, Guoqiang, Chen, Li, Ewing, Charles M, Eisenberger, Mario A, Carducci, Michael A, Nelson, William G, Yegnasubramanian, Srinivasan, Luo, Jun, Wang, Yue, Xu, Jianfeng, Isaacs, William B, Visakorpi, Tapio
Published in Nature medicine (01.05.2009)
Published in Nature medicine (01.05.2009)
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Journal Article
DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases
Aryee, Martin J, Liu, Wennuan, Engelmann, Julia C, Nuhn, Philipp, Gurel, Meltem, Haffner, Michael C, Esopi, David, Irizarry, Rafael A, Getzenberg, Robert H, Nelson, William G, Luo, Jun, Xu, Jianfeng, Isaacs, William B, Bova, G Steven, Yegnasubramanian, Srinivasan
Published in Science translational medicine (23.01.2013)
Published in Science translational medicine (23.01.2013)
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Journal Article
Health inequity drives disease biology to create disparities in prostate cancer outcomes
Nelson, William G, Brawley, Otis W, Isaacs, William B, Platz, Elizabeth A, Yegnasubramanian, Srinivasan, Sfanos, Karen S, Lotan, Tamara L, De Marzo, Angelo M
Published in The Journal of clinical investigation (01.02.2022)
Published in The Journal of clinical investigation (01.02.2022)
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Journal Article
Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma
Orr, Brent A, Haffner, Michael C, Nelson, William G, Yegnasubramanian, Srinivasan, Eberhart, Charles G
Published in PloS one (19.07.2012)
Published in PloS one (19.07.2012)
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Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers
Haffner, Michael C, Chaux, Alcides, Meeker, Alan K, Esopi, David M, Gerber, Jonathan, Pellakuru, Laxmi G, Toubaji, Antoun, Argani, Pedram, Iacobuzio-Donahue, Christine, Nelson, William G, Netto, George J, De Marzo, Angelo M, Yegnasubramanian, Srinivasan
Published in Oncotarget (01.08.2011)
Published in Oncotarget (01.08.2011)
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Journal Article
Epigenetics in Prostate Cancer: Biologic and Clinical Relevance
Jerónimo, Carmen, Bastian, Patrick J, Bjartell, Anders, Carbone, Giuseppina M, Catto, James W.F, Clark, Susan J, Henrique, Rui, Nelson, William G, Shariat, Shahrokh F
Published in European urology (01.10.2011)
Published in European urology (01.10.2011)
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Journal Article
A Prospective Study of Chronic Inflammation in Benign Prostate Tissue and Risk of Prostate Cancer: Linked PCPT and SELECT Cohorts
Platz, Elizabeth A, Kulac, Ibrahim, Barber, John R, Drake, Charles G, Joshu, Corinne E, Nelson, William G, Lucia, M Scott, Klein, Eric A, Lippman, Scott M, Parnes, Howard L, Thompson, Ian M, Goodman, Phyllis J, Tangen, Catherine M, De Marzo, Angelo M
Published in Cancer epidemiology, biomarkers & prevention (01.10.2017)
Published in Cancer epidemiology, biomarkers & prevention (01.10.2017)
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Journal Article
Procainamide Is a Specific Inhibitor of DNA Methyltransferase 1
Lee, Byron H., Yegnasubramanian, Srinivasan, Lin, Xiaohui, Nelson, William G.
Published in The Journal of biological chemistry (09.12.2005)
Published in The Journal of biological chemistry (09.12.2005)
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Journal Article
Epigenetic DNA methylation of antioxidative stress regulator NRF2 in human prostate cancer
Khor, Tin Oo, Fuentes, Francisco, Shu, Limin, Paredes-Gonzalez, Ximena, Yang, Anne Yuqing, Liu, Yue, Smiraglia, Dominic J, Yegnasubramanian, Srinivasan, Nelson, William G, Kong, Ah-Ng Tony
Published in Cancer prevention research (Philadelphia, Pa.) (01.12.2014)
Published in Cancer prevention research (Philadelphia, Pa.) (01.12.2014)
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Journal Article
Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer
Graham, Mindy K., Wang, Rulin, Chikarmane, Roshan, Abel, Bulouere, Vaghasia, Ajay, Gupta, Anuj, Zheng, Qizhi, Hicks, Jessica, Sysa-Shah, Polina, Pan, Xin, Castagna, Nicole, Liu, Jianyong, Meyers, Jennifer, Skaist, Alyza, Zhang, Yan, Rubenstein, Michael, Schuebel, Kornel, Simons, Brian W., Bieberich, Charles J., Nelson, William G., Lupold, Shawn E., DeWeese, Theodore L., De Marzo, Angelo M., Yegnasubramanian, Srinivasan
Published in Nature communications (28.08.2024)
Published in Nature communications (28.08.2024)
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A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes
Shinohara, Debika Biswal, Vaghasia, Ajay M., Yu, Shu-Han, Mak, Tim N., Brüggemann, Holger, Nelson, William G., De Marzo, Angelo M., Yegnasubramanian, Srinivasan, Sfanos, Karen S.
Published in The Prostate (01.06.2013)
Published in The Prostate (01.06.2013)
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Journal Article
DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity
Yegnasubramanian, Srinivasan, Haffner, Michael C, Zhang, Yonggang, Gurel, Bora, Cornish, Toby C, Wu, Zhijin, Irizarry, Rafael A, Morgan, James, Hicks, Jessica, DeWeese, Theodore L, Isaacs, William B, Bova, G Steven, De Marzo, Angelo M, Nelson, William G
Published in Cancer research (Chicago, Ill.) (01.11.2008)
Published in Cancer research (Chicago, Ill.) (01.11.2008)
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Journal Article
GSTP1 positive prostatic adenocarcinomas are more common in Black than White men in the United States
Vidal, Igor, Zheng, Qizhi, Hicks, Jessica L, Chen, Jiayu, Platz, Elizabeth A, Trock, Bruce J, Kulac, Ibrahim, Baena-Del Valle, Javier A, Sfanos, Karen S, Ernst, Sarah, Jones, Tracy, Maynard, Janielle P, Glavaris, Stephanie A, Nelson, William G, Yegnasubramanian, Srinivasan, De Marzo, Angelo M
Published in PloS one (30.06.2021)
Published in PloS one (30.06.2021)
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Journal Article
Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth
Lin, Jianqing, Haffner, Michael C., Zhang, Yonggang, Lee, Byron H., Brennen, W. Nathaniel, Britton, Justin, Kachhap, Sushant K., Shim, Joong Sup, Liu, Jun O., Nelson, William G., Yegnasubramanian, Srinivasan, Carducci, Michael A.
Published in The Prostate (01.03.2011)
Published in The Prostate (01.03.2011)
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Journal Article
A novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment
Platz, Elizabeth A, Yegnasubramanian, Srinivasan, Liu, Jun O, Chong, Curtis R, Shim, Joong Sup, Kenfield, Stacey A, Stampfer, Meir J, Willett, Walter C, Giovannucci, Edward, Nelson, William G
Published in Cancer discovery (01.06.2011)
Published in Cancer discovery (01.06.2011)
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Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations
Gerber, Jonathan M, Gucwa, Jessica L, Esopi, David, Gurel, Meltem, Haffner, Michael C, Vala, Milada, Nelson, William G, Jones, Richard J, Yegnasubramanian, Srinivasan
Published in Oncotarget (01.05.2013)
Published in Oncotarget (01.05.2013)
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Journal Article
MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells
Iwata, Tsuyoshi, Schultz, Denise, Hicks, Jessica, Hubbard, Gretchen K, Mutton, Laura N, Lotan, Tamara L, Bethel, Carlise, Lotz, Matthew T, Yegnasubramanian, Srinivasan, Nelson, William G, Dang, Chi V, Xu, MengMeng, Anele, Uzoma, Koh, Cheryl M, Bieberich, Charles J, De Marzo, Angelo M
Published in PloS one (25.02.2010)
Published in PloS one (25.02.2010)
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