Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells
Chute, John P, Doan, Phuong, Salter, Alice B, Russell, J Lauren, Lento, William E, Daher, Pamela, Meadows, Sarah K, Muramoto, Garrett G, Chi, Jen-Tsan, Chao, Nelson J, Reya, Tannishtha, Himburg, Heather A
Published in Nature medicine (01.04.2010)
Published in Nature medicine (01.04.2010)
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Regulation of myeloid leukaemia by the cell-fate determinant Musashi
Gerrard, Gareth, Lento, William E, Lagoo, Anand, Zimdahl, Bryan, Blum, Jordan, Radich, Jerald P, Kwon, Hyog Young, Congdon, Kendra L, Chuah, Charles, Oehler, Vivian G, Kim, Dong-Wook, Goh, Harriet, Kim, Soo-Hyun, Jordan, Craig T, Zhao, Chen, Foroni, Letizia, Ito, Takahiro, Reya, Tannishtha, Goldman, John
Published in Nature (05.08.2010)
Published in Nature (05.08.2010)
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Journal Article
CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer
Racioppi, Luigi, Nelson, Erik R, Huang, Wei, Mukherjee, Debarati, Lawrence, Scott A, Lento, William, Masci, Anna Maria, Jiao, Yiquin, Park, Sunghee, York, Brian, Liu, Yaping, Baek, Amy E, Drewry, David H, Zuercher, William J, Bertani, Francesca R, Businaro, Luca, Geradts, Joseph, Hall, Allison, Means, Anthony R, Chao, Nelson, Chang, Ching-Yi, McDonnell, Donald P
Published in Nature communications (04.06.2019)
Published in Nature communications (04.06.2019)
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Journal Article
WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum
Pei, Yanxin, Brun, Sonja N, Markant, Shirley L, Lento, William, Gibson, Paul, Taketo, Makoto M, Giovannini, Marco, Gilbertson, Richard J, Wechsler-Reya, Robert J
Published in Development (Cambridge) (15.05.2012)
Published in Development (Cambridge) (15.05.2012)
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Journal Article
Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-Induced Myeloid-Derived Suppressor Cells
Huang, Wei, Liu, Yaping, Luz, Anthony, Berrong, Mark, Meyer, Joel N, Zou, Yujing, Swann, Excel, Sundaramoorthy, Pasupathi, Kang, Yubin, Jauhari, Shekeab, Lento, William, Chao, Nelson, Racioppi, Luigi
Published in Frontiers in immunology (12.10.2021)
Published in Frontiers in immunology (12.10.2021)
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Journal Article
TGFBI Expressed by Bone Marrow Niche Cells and Hematopoietic Stem and Progenitor Cells Regulates Hematopoiesis
Klamer, Sofieke E., Dorland, Yvonne L., Kleijer, Marion, Geerts, Dirk, Lento, William E., van der Schoot, C. Ellen, von Lindern, Marieke, Voermans, Carlijn
Published in Stem cells and development (01.11.2018)
Published in Stem cells and development (01.11.2018)
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Journal Article
G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses
Tarrant, Teresa K., Billard, Matthew J., Timoshchenko, Roman G., McGinnis, Marcus W., Serafin, D. Stephen, Foreman, Oded, Esserman, Denise A., Chao, Nelson J., Lento, William E., Lee, David M., Patel, Dhavalkumar, Siderovski, David P.
Published in Journal of leukocyte biology (01.12.2013)
Published in Journal of leukocyte biology (01.12.2013)
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Journal Article
Calcium/calmodulin-dependent kinase kinase 2 regulates hematopoietic stem and progenitor cell regeneration
Racioppi, Luigi, Lento, William, Huang, Wei, Arvai, Stephanie, Doan, Phuong L, Harris, Jeffrey R, Marcon, Fernando, Nakaya, Helder I, Liu, Yaping, Chao, Nelson
Published in Cell death & disease (05.10.2017)
Published in Cell death & disease (05.10.2017)
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Journal Article
Wnt signaling in normal and malignant hematopoiesis
Lento, William, Congdon, Kendra, Voermans, Carlijn, Kritzik, Marcie, Reya, Tannishtha
Published in Cold Spring Harbor perspectives in biology (01.02.2013)
Published in Cold Spring Harbor perspectives in biology (01.02.2013)
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Journal Article
Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration
Lento, William, Ito, Takahiro, Zhao, Chen, Harris, Jeffrey R, Huang, Wei, Jiang, Chen, Owzar, Kouros, Piryani, Sadhna, Racioppi, Luigi, Chao, Nelson, Reya, Tannishtha
Published in Genes & development (01.05.2014)
Published in Genes & development (01.05.2014)
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Journal Article
Discovery of an Oral, Beyond-Rule-of-Five Mcl‑1 Protein–Protein Interaction Modulator with the Potential of Treating Hematological Malignancies
Romanov-Michailidis, Fedor, Hsiao, Chien-Chi, Urner, Lorenz M., Jerhaoui, Soufyan, Surkyn, Michel, Miller, Bradley, Vos, Ann, Dominguez Blanco, Maria, Bueters, Ruud, Vinken, Petra, Bekkers, Mariette, Walker, David, Pietrak, Beth, Eyckmans, Werner, Dores-Sousa, José Luís, Joo Koo, Seong, Lento, William, Bauser, Marcus, Philippar, Ulrike, Rombouts, Frederik J. R.
Published in Journal of medicinal chemistry (11.05.2023)
Published in Journal of medicinal chemistry (11.05.2023)
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Journal Article
Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL‑1
Demin, Samuël, Peschiulli, Aldo, Velter, Adriana I., Vos, Ann, De Boeck, Benoît, Miller, Bradley, Rombouts, Frederik J. R., Reuillon, Tristan, Lento, William, Blanco, Maria Dominguez, Jouffroy, Matthieu, Steyvers, Helena, Bekkers, Mariette, Altrocchi, Cristina, Pietrak, Beth, Koo, Seong Joo, Szewczuk, Lawrence, Attar, Ricardo, Philippar, Ulrike
Published in ACS medicinal chemistry letters (13.07.2023)
Published in ACS medicinal chemistry letters (13.07.2023)
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Journal Article
Calcium Calmodulin Dependent Kinase Kinase 2 Regulates Hematopoietic Stem Cell Regeneration and Quiescence
Lento, William, Huang, Wei, Doan, Phuong, Chao, Nelson J., Racioppi, Luigi
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
FLT3 Splice Variant (FLT3Va) As a Potential Immunotherapeutic Target in Patients with Acute Myeloid Leukemia (AML)
Adamia, Sophia, Nemeth, Jeffrey, Bhatt, Shruti, Walker, Sarah R, Voeks, Natalie I, Lento, William, Attar, Ricardo M., Galinsky, Ilene, Frank, David A, Wadleigh, Martha, Letai, Anthony, Steensma, David P., Weinstock, David M., DeAngelo, Daniel J., Dorfman, David M., Stone, Richard M., Griffin, James D
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Abstract 2133: In pursuit of MCL-1 inhibitors with improved therapeutic window for the treatment of hematological malignancies: Discovery of JNJ-4355
Rombouts, Frederik J., William, Lento, Velter, Ingrid, Vos, Ann, Peschiulli, Aldo, Tristan, Reuillon, Blanco, Maria Dominguez, Jouffroy, Matthieu, McQueen, Lisa, Steyvers, Helena, Bekkers, Mariette, Altrocchi, Cristina, Pietrak, Beth, Koo, Seong Joo, Szewczuk, Lawrence, Walker, David, Packman, Kathryn, Bueters, Ruud, Vinken, Petra, Johnson, Amy, Attar, Ricardo, Philippar, Ulrike
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Gfer inhibits Jab1-mediated degradation of p27 kip1 to restrict proliferation of hematopoietic stem cells
Teng, Ellen C., Todd, Lance R., Ribar, Thomas J., Lento, William, Dimascio, Leah, Means, Anthony R., Sankar, Uma
Published in Molecular biology of the cell (15.04.2011)
Published in Molecular biology of the cell (15.04.2011)
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Journal Article
P73. Regulation of myeloid leukemia by the cell fate determinant Musashi
Ito, Takahiro, Kwon, Hyog Young, Zimdahl, Bryan, Congdon, Kendra L., Blum, Jordan, Lento, William E., Zhao, Chen, Lagoo, Anand, Gerrard, Gareth, Foroni, Letizia, Goldman, John, Goh, Harriet, Kim, Soo-Hyun, Kim, Dong-Wook, Chuah, Charles, Oehler, Vivian G., Radich, Jerald P., Jordan, Craig T., Reya, Tannishtha
Published in Differentiation (London) (01.11.2010)
Published in Differentiation (London) (01.11.2010)
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Journal Article
Identification of Novel Regulators of Hematopoietic Stem Cell Mobilization
Voermans, Carlijn, Lento, William E., Uqoezwa, Mweia, DiMascio, Leah N., Chhotani, Ali, Rattis, Frederique M., Reya, Tannishtha
Published in Blood (16.11.2005)
Published in Blood (16.11.2005)
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