Endosome positioning coordinates spatially selective GPCR signaling
Willette, Blair K. A., Zhang, Jin-Fan, Zhang, Jin, Tsvetanova, Nikoleta G.
Published in Nature chemical biology (01.02.2024)
Published in Nature chemical biology (01.02.2024)
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A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity
Sanchez-Soto, Marta, Verma, Ravi Kumar, Willette, Blair K A, Gonye, Elizabeth C, Moore, Annah M, Moritz, Amy E, Boateng, Comfort A, Yano, Hideaki, Free, R Benjamin, Shi, Lei, Sibley, David R
Published in Science signaling (04.02.2020)
Published in Science signaling (04.02.2020)
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G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation
Sánchez-Soto, Marta, Boldizsar, Noelia M., Schardien, Kayla A., Madaras, Nora S., Willette, Blair K. A., Inbody, Laura R., Dasaro, Christopher, Moritz, Amy E., Drube, Julia, Haider, Raphael S., Free, R. Benjamin, Hoffman, Carsten, Sibley, David R.
Published in Biomolecules (Basel, Switzerland) (20.10.2023)
Published in Biomolecules (Basel, Switzerland) (20.10.2023)
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Pharmacological Characterization of the Imipridone Anticancer Drug ONC201 Reveals a Negative Allosteric Mechanism of Action at the D2 Dopamine Receptor
Free, R Benjamin, Cuoco, Caroline A, Xie, Bing, Namkung, Yoon, Prabhu, Varun V, Willette, Blair K A, Day, Marilyn M, Sanchez-Soto, Marta, Lane, J Robert, Laporte, Stéphane A, Shi, Lei, Allen, Joshua E, Sibley, David R
Published in Molecular pharmacology (01.10.2021)
Published in Molecular pharmacology (01.10.2021)
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Identification of Positive Allosteric Modulators of the D 1 Dopamine Receptor That Act at Diverse Binding Sites
Luderman, Kathryn D, Conroy, Jennie L, Free, R Benjamin, Southall, Noel, Ferrer, Marc, Sanchez-Soto, Marta, Moritz, Amy E, Willette, Blair K A, Fyfe, Tim J, Jain, Prashi, Titus, Steve, Hazelwood, Lisa A, Aubé, Jeffrey, Lane, J Robert, Frankowski, Kevin J, Sibley, David R
Published in Molecular pharmacology (01.10.2018)
Published in Molecular pharmacology (01.10.2018)
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Journal Article
Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites
Luderman, Kathryn D, Conroy, Jennie L, Free, R Benjamin, Southall, Noel, Ferrer, Marc, Sanchez-Soto, Marta, Moritz, Amy E, Willette, Blair K A, Fyfe, Tim J, Jain, Prashi, Titus, Steve, Hazelwood, Lisa A, Aubé, Jeffrey, Lane, J Robert, Frankowski, Kevin J, Sibley, David R
Published in Molecular pharmacology (01.10.2018)
Published in Molecular pharmacology (01.10.2018)
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Functional diversification of cell signaling by GPCR localization
Klauer, Matthew J., Willette, Blair K.A., Tsvetanova, Nikoleta G.
Published in The Journal of biological chemistry (01.03.2024)
Published in The Journal of biological chemistry (01.03.2024)
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Identification of Structural Elements that Regulate Signaling Bias in D2-like Dopamine Receptors
Sibley, David R., Soto, Marta Sanchez, Willette, Blair K. A., Gonye, Elizabeth C., Moore, Annah M., Moritz, Amy E., Verma, Ravi Kumar, Yano, Hideaki, Shi, Lei, Free, R Benjamin
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
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Identification of residues in the fifth transmembrane-spanning domain of the D2-like dopamine receptors that engender signaling bias
Sanchez-Soto, Marta, Willette, Blair K A, Gonye, Elizabeth C, Moore, Annah M, Chun, Lani S, Moritz, Amy E, Yano, Hideaki, Shi, Lei, Free, R Benjamin, Sibley, David R
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
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G Protein-Coupled Receptor Kinase 2 Selectively Enhances beta-Arrestin Recruitment to the D[sub.2] Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation
Sanchez-Soto, Marta, Boldizsar, Noelia M, Schardien, Kayla A, Madaras, Nora S, Willette, Blair K. A, Inbody, Laura R, Dasaro, Christopher, Moritz, Amy E, Drube, Julia, Haider, Raphael S, Free, R. Benjamin, Hoffman, Carsten, Sibley, David R
Published in Biomolecules (Basel, Switzerland) (01.10.2023)
Published in Biomolecules (Basel, Switzerland) (01.10.2023)
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Acute and chronic interactive treatments of serotonin 5HT2C and dopamine D1 receptor systems for decreasing nicotine self-administration in female rats
Willette, Blair K.A., Nangia, Anica, Howard, Sarah, DiPalma, Devon, McMillan, Collin, Tharwani, Sonum, Evans, Janequia, Wells, Corinne, Slade, Susan, Hall, Brandon J., Rezvani, Amir H., Levin, Edward D.
Published in Pharmacology, biochemistry and behavior (01.11.2019)
Published in Pharmacology, biochemistry and behavior (01.11.2019)
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Journal Article
G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D 2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation
Sánchez-Soto, Marta, Boldizsar, Noelia M, Schardien, Kayla A, Madaras, Nora S, Willette, Blair K A, Inbody, Laura R, Dasaro, Christopher, Moritz, Amy E, Drube, Julia, Haider, Raphael S, Free, R Benjamin, Hoffman, Carsten, Sibley, David R
Published in Biomolecules (Basel, Switzerland) (20.10.2023)
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Published in Biomolecules (Basel, Switzerland) (20.10.2023)
Journal Article
Acute and chronic interactive treatments of serotonin 5HT 2C and dopamine D 1 receptor systems for decreasing nicotine self-administration in female rats
Willette, Blair K A, Nangia, Anica, Howard, Sarah, DiPalma, Devon, McMillan, Collin, Tharwani, Sonum, Evans, Janequia, Wells, Corinne, Slade, Susan, Hall, Brandon J, Rezvani, Amir H, Levin, Edward D
Published in Pharmacology, biochemistry and behavior (01.11.2019)
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Published in Pharmacology, biochemistry and behavior (01.11.2019)
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